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Aysegul Batioglu-Karaaltin, Ercüment Ovali, Mehmet V Karaaltin, Murat Yener, Mehmet Yılmaz, Fatma Eyüpoğlu, Yetkin Zeki Yılmaz, Erol Rüştü Bozkurt, Necdet Demir, Esma Konuk, Ergun Süreyya Bozdağ, Özgür Yiğit, Harun Cansiz
Objectives: The purpose of this study is to shorten the decellularization time of trachea by using combination of physical, chemical, and enzymatic techniques. Methods: Approximately 3.5-cm-long tracheal segments from 42 New Zealand rabbits (3.5±0.5 kg) were separated into seven groups according to decellularization protocols. After decellularization, cellular regions, matrix and strength and endurance of the scaffold were followed up. Results: DNA content in all groups was measured under 50 ng/mg and there was no significant difference for the glycosaminoglycan content between group 3 (lyophilization+deoxycholic acid+de-oxyribonuclease method) and control group (P=0...
October 18, 2018: Clinical and Experimental Otorhinolaryngology
Esma Gökçe, Sevban Arslan
PURPOSE: The aim of this study was to investigate possible effects of video and written education on anxiety of patients undergoing coronary angiography. DESIGN: The study design was quasi-experimental. METHODS: This randomized controlled semitrial model included patients who underwent coronary angiography between October 2015 and May 2016 at the Department of Cardiology of a university hospital. The number of subjects determined by power analysis was 90 patients in three groups...
October 10, 2018: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
Melahat M Oguz, Meltem Akcaboy, Asuman Gurkan, Esma Altinel Acoglu, Pelin Zorlu, Serdar Ceylaner, Saliha Senel
No abstract text is available yet for this article.
October 2018: Minerva Pediatrica
Saloua Dimassi, Esma Karkeni, Pascal Laurant, Zouhair Tabka, Jean-François Landrier, Catherine Riva
OBJECTIVE: This study aimed to explore the role of nine microRNAs (miRNAs) in microparticles (MPs) on the efficacy of aerobic exercise in the regulation of inflammation and vascular function in obesity. METHODS: Sedentary women with normal weight (n = 6, BMI < 25 kg/m2 ) and women with obesity (n = 9, BMI > 30 kg/m2 ) were recruited at F. Hached Hospital (Sousse, Tunisia) and enrolled in an 8-week aerobic program. Vascular function was assessed using laser Doppler flowmetry/iontophoresis, circulating MPs by flow cytometry, miRNAs by real-time polymerase chain reaction, and inflammation by ELISA, before and after exercise...
October 2018: Obesity
Orçun Çiftci, Esma Nur Ünal, Zeynep Dellaloğlu, Alp Aydan, Gökçen Aksoy, Makbule Karakaş, Alp Aydınalp, Atilla Sezgin, İbrahim Haldun Müderrisoğlu, Mehmet Haberal
OBJECTIVES: Cardiac transplant is a life-saving procedure for patients with end-stage heart failure. Preoperative pulmonary vascular resistance is indicative of intrinsic pulmonary vascular disease and correlates with posttransplant survival. However, its measurement is costly and time consuming. Therefore, simpler techniques are required. Diastolic transpulmonary gradient reportedly indicates intrinsic pulmonary vascular disease. Here, we investigated the relationship between preoperative diastolic transpulmonary gradient with preoperative pulmonary vascular resistance and 1-year and overall mortality among cardiac transplant patients...
September 25, 2018: Experimental and Clinical Transplantation
Esma Altinel Acoglu, Melahat Melek Oguz, Eyup Sari, Husniye Yucel, Meltem Akcaboy, Pelin Zorlu, Sanliay Sahin, Saliha Senel
OBJECTIVES: Lumbar puncture (LP) is fundamental for diagnosis and treatment; however, some parents do not provide consent for their children to undergo the procedure, which can make diagnosis and determination of the optimal treatment difficult. The present study aimed to describe the level of knowledge and attitudes toward LP of parents whose children were scheduled to undergo the procedure. METHODS: A prospective cross-sectional descriptive study of a convenience sample of parents of 84 children aged 2 months to 17 years scheduled for LP at a single academic children's hospital between 2015 and 2017...
September 21, 2018: Pediatric Emergency Care
Fatma Tuğçe Gürağaç Dereli, Mert Ilhan, Esma Kozan, Esra Küpeli Akkol
Polygonum cognatum Meissn. (Polygonaceae) is a wild edible plant known locally as "solucanotu, madimak" in Turkey and it has been used for various purposes, such as diuretic and antidiabetic, as well to treat oxyuris and worms internally in humans. The present study was carried out to investigate the anthelmintic activity of various extracts were obtained from the aerial parts of P. cognatum in order to justify its traditional usage in Turkish folk medicine. n-Hexane, ethyl acetate and methanol extracts were prepared from the aerial parts of the plant, successively...
September 17, 2018: Experimental Parasitology
Thomas J Kandl, Oded Sagiv, Jonathan L Curry, Jing Ning, Junsheng Ma, Courtney W Hudgens, John Van Arnam, Jennifer A Wargo, Bita Esmaeli, Michael T Tetzlaff
Ocular adnexal sebaceous carcinoma (OASC) is an aggressive malignancy that frequently recurs locally and metastasizes. Surgical extirpation may produce significant aesthetic morbidity, and effective systemic therapies for locally advanced or metastatic disease are largely ineffective. Immune checkpoint inhibitors have shown efficacy in the management of several solid tumors where tumor cell PD-L1 expression correlates with improved response. To determine whether OASC might be amenable to immune checkpoint blockade, we performed comprehensive immune profiling for CD3, CD8, PD-1, FOXP3, and PD-L1 in 24 patients with primary OASC...
2018: Oncoimmunology
Esma Islamaj, Caroline P Jordaan-Kuip, Koen A Vermeer, Hans G Lemij, Peter W T de Waard
Purpose: The purpose of this study was to quantify any diplopia and motility changes after the implantation of a Baerveldt glaucoma implant (BGI) or after trabeculectomy (TE). Methods: We analyzed 51 patients with a BGI and 52 patients with a TE from a prospective cohort study. To quantify any diplopia, we asked patients about the presence of diplopia at 1 year after surgery. To quantify any ocular motility changes, we measured ductions in eight gaze directions, the patients' ocular alignment and their fusion range before and 1 year after surgery...
September 2018: Translational Vision Science & Technology
Esma Altinel Acoglu, Saliha Senel
No abstract text is available yet for this article.
August 15, 2018: Indian Pediatrics
Elena V Kazakova, Meijun Chen, Esma Jamaspishvili, Zhang Lin, Jingling Yu, Lulu Sun, Hong Qiao
Two recent studies found that RBMS1 gene rs7593730 and BCAR1 gene rs7202877 are related to type 2 diabetes. However, the association of these loci with type 2 diabetes mellitus (T2DM) has not been examined in Chinese. We performed a replication study to investigate the association of the 2 susceptibility loci with T2DM in the Chinese population. We genotyped 1961 Chinese participants (991 with T2DM and 970 controls) for each of the 2 single nucleotide polymorphisms (SNPs) rs7593730 in RBMS1 and rs7202877 near BCAR1 using SNPscan and examined their association with T2DM using logistic regression analysis...
2018: Acta Biochimica Polonica
Esma Cihan, Dale C Hesdorffer, Michael Brandsoy, Ling Li, David R Fowler, Jason K Graham, Elizabeth J Donner, Orrin Devinsky, Daniel Friedman
OBJECTIVE: Both drowning and sudden unexpected death in epilepsy (SUDEP) are diagnoses of exclusion with predominantly nonspecific autopsy findings. We hypothesized that people with epilepsy found dead in water with no clear sign of submersion could be misdiagnosed as SUDEP. METHODS: All reported seizure-related deaths undergoing medicolegal investigation in three medical examiner's offices (New York City, Maryland, San Diego County) over different time periods were reviewed to identify epilepsy-related drownings and SUDEPs...
August 26, 2018: Epilepsia
Ho-Seok Sa, Maria Laura Rubin, Shiqiong Xu, Jing Ning, Michael Tetzlaff, Oded Sagiv, Thomas J Kandl, Bita Esmaeli
BACKGROUND/AIMS: To validate the predictive value of the American Joint Committee on Cancer (AJCC) 8th-edition classification for local recurrence, metastasis and survival in patients with eyelid sebaceous carcinoma. METHODS: We performed a retrospective review of 100 consecutive patients with eyelid sebaceous carcinoma. Eyelid carcinomas were staged according to the AJCC 7th-edition and 8th-edition criteria. Associations between T and N categories and disease-related outcomes including local recurrence, lymph node metastasis, distant metastasis and survival were evaluated...
August 21, 2018: British Journal of Ophthalmology
Oded Sagiv, Sudip D Thakar, John T Manning, Thomas J Kandl, Luis E Fayad, Nathan Fowler, Fredrick B Hagemeister, Michelle A Fanale, Chelsea C Pinnix, Felipe Samaniego, Bita Esmaeli
PURPOSE: The authors examined the prevalence of a histologic change of ocular adnexal lymphoma (OAL) grade in patients with a history of lymphoma in nonocular sites. METHODS: In this retrospective study, the authors reviewed the clinical and pathological data of 209 patients with OAL treated by the senior author during 2000 to 2017. RESULTS: Of 209 patients with OAL, 65 (31%) had a history of lymphoma. In 54 of the 65 patients (83%), the original lymphoma and OAL were of the same histologic type...
August 17, 2018: Ophthalmic Plastic and Reconstructive Surgery
Muhammad A Memon, Burcak Karaca, Rasha Aboelhassan, Mohsen Barsoum, Mustafa Erman, Mert Basaran, Alper Sevinc, Djedi Hanene, Cassandra Slader, Virginia Pilipovic, Kerboua Esma, Bouzid Kamel
PURPOSE: Soft tissue sarcomas (STS) are a heterogeneous group of rare mesenchymal neoplasms, accounting for < 1% of all newly diagnosed malignancies. These tumors can occur in almost any anatomic site though they most frequently occur in the extremities. The objective of the study was to describe the epidemiology, treatment paradigm, and real-world outcomes in the clinical management of metastatic STS (mSTS) in the Middle East and North Africa (MEA) region. METHODS: MOON was an observational, multicenter, retrospective patient chart review study which included 200 patients with mSTS in the final analysis...
August 13, 2018: Journal of Cancer Research and Clinical Oncology
Halil Ibrahim Guler, Esma Ceylan, Sabriye Canakci, Ali Osman Belduz
A cryptic plasmid pHIG22 from Thermus scotoductus sp. K6, an isolate from the Alangullu Hot Spring (Aydin, Turkey), was sequenced and characterized. The pHIG22 plasmid is a multicopy, double stranded and 2222 bp circular molecule with 62.78% GC content, which shows a characteristical nucleotide sequence without any homology to other known plasmids. Five open reading frames were predicted based on the nucleotide sequence analysis. The deduced amino acid sequence of all predicted ORFs didn't show any similarity with any known proteins...
December 30, 2018: Gene
Abdul Albilali, Esma Dilli
PURPOSE OF REVIEW: To provide an updated overview of Photophobia with a particular focus on photophobia related to migraine. RECENT FINDINGS: Melanopsin-containing photoreceptors called intrinsically photosensitive retinal ganglion cells (ipRGCs) have been identified in the retina and explain the rational for photophobia in individuals who are blind. Photophobia, a sensory disturbance provoked by light, is a common neurological and ophthalmological symptom. Migraine, a common neurological condition, is pathognomonic of photophobia; however, other primary headache conditions, traumatic brain injury, and impairment of the optic pathway can cause photophobia...
July 30, 2018: Current Neurology and Neuroscience Reports
Sunah Kang, Ji Won Seo, Chan Joo Ahn, Bita Esmaeli, Ho-Seok Sa
AIM: To calculate a regression formula for intraoperative lagophthalmos to determine the amount of correction in levator resection for mild to moderate congenital ptosis. METHODS: This retrospective study included 38 eyelids from 28 consecutive children with congenital ptosis with levator function of 4 mm or better who showed satisfactory surgical outcomes defined as postoperative margin reflex distance-1 (MRD1) ≥3 mm in each eye and difference in MRD1 ≤1 mm between eyes at 6 months after levator resection...
July 26, 2018: British Journal of Ophthalmology
Füsun Erdenen, Hülya Güngel, Esma Altunoğlu, Duygu Şak, Cüneyt Müderrisoğlu, Atakan Koro, Pınar Akça Güler, Muzaffer Ece Hakan Sahin, Gonul Simsek, Hafize Uzun
BACKGROUND: Diabetic retinopathy (DR) is mainly caused by metabolic factors, vascular inflammation, and endothelial dysfunction. We aimed to evaluate the relationship of DR with inflammatory and biochemical alterations in type 2 diabetics. METHODS: A total of 89 diabetic patients with retinopathy [(DR (+) (n = 30)], without retinopathy [(DR (-) (n = 32)], and 27 control subjects were involved in the study. Demographic properties, biochemical values, ophtalmologic evaluation, C-reactive protein (CRP), and pentraxin-3 (PTX-3) levels were recorded...
September 2018: Metabolic Syndrome and related Disorders
Martine J Jager, Niels J Brouwer, Bita Esmaeli
No abstract text is available yet for this article.
August 2018: Ophthalmology
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