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Photobiomodulation

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https://www.readbyqxmd.com/read/28888911/photobiomodulation-with-670%C3%A2-nm-light-ameliorates-m%C3%A3-ller-cell-mediated-activation-of-microglia-and-macrophages-in-retinal-degeneration
#1
Yen-Zhen Lu, Riccardo Natoli, Michele Madigan, Nilisha Fernando, Kartik Saxena, Riemke Aggio-Bruce, Haihan Jiao, Jan Provis, Krisztina Valter
Müller cells, the supporting cells of the retina, play a key role in responding to retinal stress by releasing chemokines, including CCL2, to recruit microglia and macrophages (MG/MΦ) into the damaged retina. Photobiomodulation (PBM) with 670 nm light has been shown to reduce inflammation in models of retinal degeneration. In this study, we aimed to investigate whether 670 nm light had an effect on Müller cell-initiated inflammation under retinal photo-oxidative damage (PD) in vivo and in vitro. Sprague-Dawley rats were pre-treated with 670 nm light (9J/cm(2)) once daily over 5 days prior to PD...
September 6, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28867926/quantum-dot-light-emitting-devices-for-photomedical-applications
#2
Hao Chen, Juan He, Raymond Lanzafame, Istvan Stadler, Hamid El Hamidi, Hui Liu, Jonathan Celli, Michael R Hamblin, Yingying Huang, Emily Oakley, Gal Shafirstein, Ho-Kyoon Chung, Shin-Tson Wu, Yajie Dong
While OLEDs have struggled to find a niche lighting application that can fully take advantage of their unique form factors as thin, flexible, lightweight and uniformly large-area luminaire, photomedical researchers have been in search of low-cost, effective illumination devices with such form factors that could facilitate widespread clinical applications of photodynamic therapy (PDT) or photobiomodulation (PBM). Although existing OLEDs with either fluorescent or phosphorescent emitters cannot achieve the required high power density at the right wavelength windows for photomedicine, the recently developed ultrabright and efficient deep red quantum dot light emitting devices (QLEDs) can nicely fit into this niche...
March 2017: Journal of the Society for Information Display
https://www.readbyqxmd.com/read/28853245/treatment-of-peripheral-vestibular-dysfunction-using-photobiomodulation
#3
Min Young Lee, Jai-Hwan Hyun, Myung-Whan Suh, Jin-Chul Ahn, Phil-Sang Chung, Jae Yun Jung, Chung Ku Rhee
Gentamicin, which is still used in modern medicine, is a known vestibular toxic agent, and various degrees of balance problems have been observed after exposure to this pharmacologic agent. Photobiomodulation is a candidate therapy for vertigo due to its ability to reach deep inner ear organs such as the cochlea. Previous reports have suggested that photobiomodulation can improve hearing and cochlea function. However, few studies have examined the effect of photobiomodulation on balance dysfunction. We used a rat model to mimic human vestibulopathy resulting from gentamicin treatment and evaluated the effect of photobiomodulation on vestibular toxicity...
August 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28846932/effect-of-in-vivo-low-level-laser-therapy-on-bone-marrow-derived-mesenchymal-stem-cells-in-ovariectomy-induced-osteoporosis-of-rats
#4
Ataroalsadat Mostafavinia, Leila Dehdehi, Seyed Kamran Ghoreishi, Behnam Hajihossainlou, Mohammad Bayat
Postmenopausal osteoporosis (PMOP) is considered by decreased bone strength that escalates the threat of fractures. Positive effects of photobiomodulation (PBM) with pulse wave have been demonstrated in cell culture and animal models. The aim of this study was to assess the in vivo effects of PBM on viability and calcium ion release of ovariectomy induced osteoporosis (OVX) - bone marrow derived mesenchymal stem cells (BMMSCs). MATERIAL AND METHODS: 18 female rats were distributed into the following groups: 1) control healthy, 2) LASER-healthy (890nm, 80Hz, 1...
August 18, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28846931/stimulation-of-morphofunctional-repair-of-the-facial-nerve-with-photobiomodulation-using-the-end-to-side-technique-or-a-new-heterologous-fibrin-sealant
#5
Marcelie Priscila de Oliveira Rosso, Geraldo Marco Rosa Júnior, Daniela Vieira Buchaim, Iris Jasmin Santos German, Karina Torres Pomini, Rafael Gomes de Souza, Mizael Pereira, Idvaldo Aparecido Favaretto Júnior, Cleuber Rodrigo de Souza Bueno, Jéssica Barbosa de Oliveira Gonçalves, Rui Seabra Ferreira Júnior, Benedito Barraviera, Jesus Carlos Andreo, Rogério Leone Buchaim
This research evaluated the influence of Photobiomodulation Therapy (PBMT) on lesions of the facial nerve repaired with the end-to-side technique or coaptation with a new heterologous fibrin sealant. Thirty-two Wistar rats were separated into 5 groups: Control group (CG), where the buccal branch of the facial nerve was collected; Experimental Suture Group (ESG) and Experimental Fibrin Group (EFG), in which the buccal branch was end-to-side sutured to the zygomatic branch on the right side of the face or coaptated with fibrin sealant on the left side; Experimental Suture Laser Group (ESLG) and Experimental Fibrin Laser Group (EFLG), in which the same procedures were performed as the ESG and EFG, associated with PBMT (wavelength of 830nm, energy density 6...
August 18, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28840431/cdna-microarray-analysis-of-human-keratinocytes-cells-of-patients-submitted-to-chemoradiotherapy-and-oral-photobiomodulation-therapy-pilot-study
#6
Heliton S Antunes, Gabriel Wajnberg, Marcos B Pinho, Natasha Andressa Nogueira Jorge, Joyce Luana Melo de Moraes, Claudio Gustavo Stefanoff, Daniel Herchenhorn, Carlos M M Araújo, Celia Maria Pais Viégas, Mariana P Rampini, Fernando L Dias, Patricia Savio de Araujo-Souza, Fabio Passetti, Carlos G Ferreira
Oral mucositis is an acute toxicity that occurs in patients submitted to chemoradiotherapy to treat head and neck squamous cell carcinoma. In this study, we evaluated differences in gene expression in the keratinocytes of the oral mucosa of patients treated with photobiomodulation therapy and tried to associate the molecular mechanisms with clinical findings. From June 2009 to December 2010, 27 patients were included in a randomized double-blind pilot study. Buccal smears from 13 patients were obtained at days 1 and 10 of chemoradiotherapy, and overall gene expression of samples from both dates were analyzed by complementary DNA (cDNA) microarray...
August 24, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28840382/new-photobiomodulation-protocol-prevents-oral-mucositis-in-hematopoietic-stem-cell-transplantation-recipients-a-retrospective-study
#7
Camila Weissheimer, Marina Curra, Lauro J Gregianin, Liane E Daudt, Vivian P Wagner, Marco Antonio T Martins, Manoela D Martins
Oral mucositis (OM) is an adverse side effect among hematopoietic stem cell transplantation (HSCT) recipients. The objective of this retrospective study was to evaluate the preventive effect of photobiomodulation (PBM) applied three times per week versus seven times per week in patients undergoing HSCT. The risk factors related to the incidence and severity of OM were also assessed. This was a retrospective study that evaluated 99 HSCT recipients who received different PBM protocols. Group I received three sessions per week, and group II received daily treatment...
August 24, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28812164/efficacy-of-fractional-lasers-in-treating-alopecia-a-literature-review
#8
Marina Perper, Adam S Aldahan, Rachel A Fayne, Christopher P Emerson, Keyvan Nouri
Hair loss stemming from different types of alopecia, such as androgenic alopecia and alopecia areata, negatively affects over half the population and, in many circumstances, causes serious psychosocial distress. Current treatment options for alopecia, such as minoxidil, anthralin, and intralesional corticosteroids, vary efficacy and side effect profiles. It is known that low-level laser/light therapies (LLLT), or photobiomodulations, such as the US FDA-cleared HairMax Lasercomb®, He-Ne laser, and excimer laser, are relatively affordable, user-friendly, safe, and effective forms of treatment for hair loss...
August 16, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28801810/effects-of-pbm-in-different-energy-densities-and-irradiance-on-maintaining-cell-viability-and-proliferation-of-pulp-fibroblasts-from-human-primary-teeth
#9
Nádia Carolina Teixeira Marques, Natalino Lourenço Neto, Mariel Tavares Oliveira Prado, Luciana Lourenço Ribeiro Vitor, Rodrigo Cardoso Oliveira, Vivien Thiemy Sakai, Carlos Ferreira Santos, Maria Aparecida Andrade Moreira Machado, Thais Marchini Oliveira
This study aimed to compare the effects of photobiomodulation (PBM) in different energy densities and irradiances on maintaining cell viability, and proliferation of pulp fibroblasts from human primary teeth (HPF) were cultured in DMEM and used between the fourth and eighth passages. Then, HPF were irradiated with the following different energy densities: 1.25 J/cm(2) (a), 2.50 J/cm(2) (b), 3.75 J/cm(2) (c), 5.00 J/cm(2) (d), and 6.25 J/cm(2) (e); but varying either the time of irradiation (groups 1a-1e) or the output power (groups 2a-2e)...
August 11, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28798481/red-660%C3%A2-nm-or-near-infrared-810%C3%A2-nm-photobiomodulation-stimulates-while-blue-415%C3%A2-nm-green-540%C3%A2-nm-light-inhibits-proliferation-in-human-adipose-derived-stem-cells
#10
Yuguang Wang, Ying-Ying Huang, Yong Wang, Peijun Lyu, Michael R Hamblin
We previously showed that blue (415 nm) and green (540 nm) wavelengths were more effective in stimulating osteoblast differentiation of human adipose-derived stem cells (hASC), compared to red (660 nm) and near-infrared (NIR, 810 nm). Intracellular calcium was higher after blue/green, and could be inhibited by the ion channel blocker, capsazepine. In the present study we asked what was the effect of these four wavelengths on proliferation of the hASC? When cultured in proliferation medium there was a clear difference between blue/green which inhibited proliferation and red/NIR which stimulated proliferation, all at 3 J/cm(2)...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28795275/effects-of-photobiomodulation-therapy-and-topical-non-steroidal-anti-inflammatory-drug-on-skeletal-muscle-injury-induced-by-contusion-in-rats-part-2-biochemical-aspects
#11
Shaiane Silva Tomazoni, Lúcio Frigo, Tereza Cristina Dos Reis Ferreira, Heliodora Leão Casalechi, Simone Teixeira, Patrícia de Almeida, Marcelo Nicolas Muscara, Rodrigo Labat Marcos, Andrey Jorge Serra, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior
Muscle injuries trigger an inflammatory process, releasing important biochemical markers for tissue regeneration. The use of non-steroidal anti-inflammatory drugs (NSAIDs) is the treatment of choice to promote pain relief due to muscle injury. NSAIDs exhibit several adverse effects and their efficacy is questionable. Photobiomodulation therapy (PBMT) has been demonstrated to effectively modulate inflammation induced from musculoskeletal disorders and may be used as an alternative to NSAIDs. Here, we assessed and compared the effects of different doses of PBMT and topical NSAIDs on biochemical parameters during an acute inflammatory process triggered by a controlled model of contusion-induced musculoskeletal injury in rats...
August 9, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28793884/therapeutic-comparison-between-treatments-for-vulvar-lichen-sclerosus-study-protocol-of-a-randomized-prospective-and-controlled-trial
#12
Renata A Belotto, Maria Cristina Chavantes, João Paulo Tardivo, Roberto Euzébio Dos Santos, Raquel Civolani Marques Fernandes, Anna Carolina Ratto Tempestini Horliana, Christiane Pavani, Daniela Fátima Teixeira da Silva
BACKGROUND: Vulvar lichen sclerosus (VLS) is a lymphocyte-mediated disease of unknown etiology that can cause intense itching as well stenosis, hindering the evacuation and urination. It can also limit the sex life due to severe local pruritus, pain and dyspareunia (pain during sexual intercourse). The standard treatment for this disease is the use of topical corticosteroids to reduce the clinical symptoms and to try to increase disease-free intervals. Photodynamic therapy (PDT), a treatment that associates a light radiation with a photosensitizing agent and photobiomodulation (PBM) are therapies that can promote effective immunomodulatory responses at the application site by means of photophysical and photochemical phenomena from the molecular to the systemic level, which promote their use in chronic dermatoses...
August 10, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28783466/the-history-of-photobiomodulation-endre-mester-1903-1984
#13
Andrew Mester, Adam Mester
No abstract text is available yet for this article.
August 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28783465/photobiomodulation-in-the-prevention-of-tooth-sensitivity-caused-by-in-office-dental-bleaching-a-randomized-placebo-preliminary-study
#14
Andrea Paiva Corsetti Calheiros, Maria Stella Moreira, Flávia Gonçalves, Ana Cecília Correa Aranha, Sandra Ribeiro Cunha, Carolina Steiner-Oliveira, Carlos de Paula Eduardo, Karen Müller Ramalho
OBJECTIVE: Analyze the effect of photobiomodulation in the prevention of tooth sensitivity after in-office dental bleaching. BACKGROUND DATA: Tooth sensitivity is a common clinical consequence of dental bleaching. Therapies for prevention of sensitivity have been investigated in literature. MATERIALS AND METHODS: This study was developed as a randomized, placebo blind clinical trial. Fifty patients were selected (n = 10) and randomly divided into five groups: (1) control, (2) placebo, (3) laser before bleaching, (4) laser after bleaching, and (5) laser before and after bleaching...
August 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28776111/methylene-blue-mediated-photobiomodulation-on-human-osteoblast-cells
#15
Gamze Bölükbaşı Ateş, Ayşe Ak, Bora Garipcan, Murat Gülsoy
Photobiomodulation (PBM) and photodynamic therapy (PDT) are two major methods, which use light in medicine and dentistry. PBM uses low-level laser light to induce cell proliferation and activity. In contrast, PDT use laser light combined with a photosensitizer (PS) to cause cell death. Due to similar, not fully understood mechanisms and biphasic response of light, unexpected and complex outcomes may be observed. In the present study, the effect of 635 nm laser light, with power density 50 mW/cm(2), at three different energy densities (0...
August 4, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28756937/short-pulse-neodymium-yttrium-aluminium-garnet-nd-yag-1064nm-laser-irradiation-photobiomodulates-mitochondria-activity-and-cellular-multiplication-of-paramecium-primaurelia-protozoa
#16
Andrea Amaroli, Alberico Benedicenti, Silvia Ravera, Steven Parker, Wayne Selting, Isabella Panfoli, Stefano Benedicenti
Few studies exist to explore the potential photobiomodulation (PBM) effect of neodymium:yttrium-aluminium garnet (Nd:YAG) laser irradiation using a flat-top handpiece delivery system. In this study, we explored the photobiomodulation effect of that laser, on Paramecium primaurelia. The parameters for the different study groups were: 0.50W, 10Hz, 100msp, 30J/cm(2); 0.75W, 10Hz, 100msp, 45J/cm(2); 1.00W, 10Hz, 100msp, 60J/cm(2); 1.25W, 10Hz, 100msp, 75J/cm(2) and 1.50W, 10Hz, 100msp, 90J/cm(2). Our results suggest that only the parameter 0...
June 19, 2017: European Journal of Protistology
https://www.readbyqxmd.com/read/28752263/photobiomodulation-therapy-by-nir-laser-in-persistent-pain-an-analytical-study-in-the-rat
#17
Laura Micheli, Lorenzo Di Cesare Mannelli, Elena Lucarini, Francesca Cialdai, Leonardo Vignali, Carla Ghelardini, Monica Monici
Over the past three decades, physicians have used laser sources for the management of different pain conditions obtaining controversial results that call for further investigations. In order to evaluate the pain relieving possibilities of photobiomodulation therapy (PBMT), we tested two near infrared (NIR) laser systems, with different power, against various kinds of persistent hyperalgesia animal models. In rats, articular pain was reproduced by the intra-articular injection of sodium monoiodoacetate (MIA) and complete Freund's adjuvant (CFA), while compressive neuropathy was modelled by the chronic constriction injury of the sciatic nerve (CCI)...
July 28, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28748217/mechanisms-and-applications-of-the-anti-inflammatory-effects-of-photobiomodulation
#18
Michael R Hamblin
Photobiomodulation (PBM) also known as low-level level laser therapy is the use of red and near-infrared light to stimulate healing, relieve pain, and reduce inflammation. The primary chromophores have been identified as cytochrome c oxidase in mitochondria, and calcium ion channels (possibly mediated by light absorption by opsins). Secondary effects of photon absorption include increases in ATP, a brief burst of reactive oxygen species, an increase in nitric oxide, and modulation of calcium levels. Tertiary effects include activation of a wide range of transcription factors leading to improved cell survival, increased proliferation and migration, and new protein synthesis...
2017: AIMS Biophysics
https://www.readbyqxmd.com/read/28742438/effect-of-low-level-laser-therapy-on-bone-regeneration-during-osseointegration-and-bone-graft
#19
Randa Zein, Wayne Selting, Stefano Benedicenti
BACKGROUND: The effect of low-level laser therapy (LLLT) on bone regeneration during osseointegration and bone graft is very controversial. Despite many positive reports of in vitro and in vivo studies and more than 50 randomized clinical trials claiming a positive effect of photobiomodulation (PBM), many reports found no significant effect of lasers. OBJECTIVE: The aim of this study was to evaluate studies correlating PBM and bone regeneration and to assesses parameters that produce positive results based on dose and output power used...
July 21, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28725994/evaluation-of-the-effects-of-photobiomodulation-on-vertebras-in-two-rat-models-of-experimental-osteoporosis
#20
Mohammadjavad Fredoni, Mahdi Ghatrehsamani, Mohammad-Amin Abdollahifar, Sahar Bayat, Mohammad Bayat
The aim of this study was to evaluate the effects of photobiomodulation (PBM) on cancellous bone in rat models of ovariectomized induced osteoporosis (OVX-D) and glucocorticoid-induced osteoporosis (GIOP). The experiment comprised of nine groups. A group of healthy rats was used for baseline evaluations. The OVX-D rats were further divided into groups as follows: control rats with osteoporosis, OVX-D rats that received alendronate (1 mg/kg 60 days), OVX-D rats treated with pulsed wave laser (890 nm, 80 Hz, 900 s, 0...
July 19, 2017: Lasers in Medical Science
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