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Photobiomodulation

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https://www.readbyqxmd.com/read/28091848/a-novel-combination-treatment-to-stimulate-bone-healing-and-regeneration-under-hypoxic-conditions-photobiomodulation-and-melatonin
#1
Jang-Ho Son, Bong-Soo Park, In-Ryoung Kim, Iel-Yong Sung, Yeong-Cheol Cho, Jung-Soo Kim, Yong-Deok Kim
Melatonin has anabolic effects on the bone, even under hypoxia, and laser irradiation has been shown to improve osteoblastic differentiation. The aim of this study was to investigate whether laser irradiation and melatonin would have synergistic effects on osteoblastic differentiation and mineralization under hypoxic conditions. MC3T3-E1 cells were exposed to 1% oxygen tension for the hypoxia condition. The cells were divided into four groups: G1-osteoblast differentiation medium only (as the hypoxic condition), G2-treatment with 50 μM melatonin only, G3-laser irradiation (808 nm, 80 mW, GaAlAs diode) only, and G4-treatment with 50 μM melatonin and laser irradiation (808 nm, 80 mW, GaAlAs diode)...
January 13, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28078845/effect-of-low-energy-light-irradiation-by-light-emitting-diode-on-u937-cells
#2
G Spoto, V De Iuliis, M Petrini, V Flati, J Di Gregorio, D Vitale, M Caruso, V Dadorante, M Ciarmoli, I Robuffo, S Martinotti, E Toniato
Photobiomodulation (PBM) can induce a set of different biological modulators either in vitro or in vivo. Experimental evidence has highlighted the role of light effects on the mechanisms related to inflammation, apoptosis and autophagy. The goal of this project was the evaluation of PBM on U937, an established cell line of histiocytic lymphoma origin. Several aspects of modulation of proinflammatory pathways were analyzed and autophagic and proapoptotic mechanisms related to low laser light exposure of cells were studied...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28075022/the-mechanistic-basis-for-photobiomodulation-therapy-of-neuropathic-pain-by-near-infrared-laser-light
#3
Vanessa Milanesi Holanda, Maria Cristina Chavantes, Xingjia Wu, Juanita J Anders
BACKGROUND AND OBJECTIVE: Various irradiances have been reported to be beneficial for the treatment of neuropathic pain with near infrared light. However, the mechanistic basis for the beneficial outcomes may vary based on the level of irradiance or fluence rate used. Using in vivo and in vitro experimental models, this study determined the mechanistic basis of photobiomodulation therapy (PBMT) for the treatment of neuropathic pain using a high irradiance. STUDY DESIGN/MATERIALS AND METHODS: In vitro experiments: Cultured, rat DRG were randomly assigned to control or laser treatment (LT) groups with different irradiation times (2, 5, 30, 60, or 120 seconds)...
January 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28070154/proposed-mechanisms-of-photobiomodulation-or-low-level-light-therapy
#4
Lucas Freitas de Freitas, Michael R Hamblin
Photobiomodulation (PBM) also known as low-level laser (or light) therapy (LLLT), has been known for almost 50 years but still has not gained widespread acceptance, largely due to uncertainty about the molecular, cellular, and tissular mechanisms of action. However, in recent years, much knowledge has been gained in this area, which will be summarized in this review. One of the most important chromophores is cytochrome c oxidase (unit IV in the mitochondrial respiratory chain), which contains both heme and copper centers and absorbs light into the near-infra-red region...
May 2016: IEEE Journal of Selected Topics in Quantum Electronics
https://www.readbyqxmd.com/read/28063017/the-photobiomodulation-effect-of-higher-fluence-808-nm-laser-therapy-with-a-flat-top-handpiece-on-the-wound-healing-of-the-earthworm-dendrobaena-veneta-a-brief-report
#5
Andrea Amaroli, Sara Ferrando, Reem Hanna, Lorenzo Gallus, Alberico Benedicenti, Sonia Scarfì, Marina Pozzolini, Stefano Benedicenti
No abstract text is available yet for this article.
January 6, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28056213/are-miqe-guidelines-being-adhered-to-in-qpcr-investigations-in-photobiomodulation-experiments
#6
Nicolette N Houreld
No abstract text is available yet for this article.
January 5, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28056208/the-effect-of-photobiomodulation-on-the-sea-urchin-paracentrotus-lividus-echinodermata-by-using-higher-fluence-on-fertilization-embryogenesis-and-larval-development-an-in-vitro-study
#7
Andrea Amaroli, Chiara Gambardella, Sara Ferrando, Reem Hanna, Alberico Benedicenti, Lorenzo Gallus, Marco Faimali, Stefano Benedicenti
OBJECTIVE: The aim of this study was to investigate the photobiomodulation (PBM) effect of the 808 nm diode laser irradiation on spermatozoa, eggs, fertilized eggs, embryos, and larvae of Paracentrotus lividus, using two different power settings. BACKGROUND DATA: Studies have shown the possible use of PBM in artificial insemination. These have shown the potential effect of low-power laser irradiation on spermatozoa, while there are few studies on the effect of laser photonic energy on oocytes and almost no reports on the influence of lasers in embryogenesis...
December 30, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28055687/personalizing-photobiomodulation-therapy
#8
E-Liisa Laakso
No abstract text is available yet for this article.
January 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28054262/does-photobiomodulation-therapy-is-better-than-cryotherapy-in-muscle-recovery-after-a-high-intensity-exercise-a-randomized-double-blind-placebo-controlled-clinical-trial
#9
Thiago De Marchi, Vinicius Mazzochi Schmitt, Guilherme Pinheiro Machado, Juliane Souza de Sene, Camila Dallavechia de Col, Olga Tairova, Mirian Salvador, Ernesto Cesar Pinto Leal-Junior
This study aimed to determine the effectiveness of photobiomodulation therapy (PBMT) and cryotherapy, in isolated and combined forms, as muscle recovery techniques after muscle fatigue-inducing protocol. Forty volunteers were randomly divided into five groups: a placebo group (PG); a PBMT group (PBMT); a cryotherapy group (CG); a cryotherapy-PBMT group (CPG); and a PBMT-cryotherapy group (PCG). All subjects performed four sessions at 24-h intervals, during which they submitted to isometric assessment (MVC) and blood collection in the pre-exercise period, and 5 and 60 min post-exercise, while the muscle fatigue induction protocol occurred after the pre-exercise collections...
January 5, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28001759/transcranial-low-level-laser-light-therapy-for-brain-injury
#10
Connor Thunshelle, Michael R Hamblin
BACKGROUND: Low-level laser therapy (LLLT) or photobiomodulation (PBM) is a possible treatment for brain injury, including traumatic brain injury (TBI). METHODS: We review the fundamental mechanisms at the cellular and molecular level and the effects on the brain are discussed. There are several contributing processes that have been proposed to lead to the beneficial effects of PBM in treating TBI such as stimulation of neurogenesis, a decrease in inflammation, and neuroprotection...
December 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28001757/photobiomodulation-triple-treatment-in-peripheral-nerve-injury-nerve-and-muscle-response
#11
Mira M Mandelbaum-Livnat, Mara Almog, Moshe Nissan, Emmanuel Loeb, Yuval Shapira, Shimon Rochkind
BACKGROUND: Muscle preservation or decrease in muscle degeneration and progressive atrophy are major challenges in patients with severe peripheral nerve injury (PNI). Considerable interest exists in the potential therapeutic value of laser phototherapy (photobiomodulation) for restoring denervated muscle atrophy and for enhancing regeneration of severely injured peripheral nerves. As previously published, the laser phototherapy has a protective and immediate effect in PNI. Laser phototherapy in the early stages of muscle atrophy may preserve the denervated muscle by maintaining creatinine kinase (CK) activity and the amount of acetylcholine receptor (AChR)...
December 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28001756/transcranial-red-near-infrared-light-emitting-diode-therapy-to-improve-cognition-in-chronic-traumatic-brain-injury
#12
Margaret A Naeser, Paula I Martin, Michael D Ho, Maxine H Krengel, Yelena Bogdanova, Jeffrey A Knight, Megan K Yee, Ross Zafonte, Judith Frazier, Michael R Hamblin, Bang-Bon Koo
We review the general topic of traumatic brain injury (TBI) and our research utilizing transcranial photobiomodulation (tPBM) to improve cognition in chronic TBI using red/near-infrared (NIR) light-emitting diodes (LEDs) to deliver light to the head. tPBM improves mitochondrial function increasing oxygen consumption, production of adenosine triphosphate (ATP), and improving cellular energy stores. Nitric oxide is released from the cells increasing regional blood flow in the brain. Review of published studies: In our previously published study, 11 chronic TBI patients with closed-head TBI caused by different accidents (motor vehicle accident, sports-related, improvised explosive device blast injury) and exhibiting long-lasting cognitive dysfunction received 18 outpatient treatments (Monday, Wednesday, Friday for 6 weeks) starting at 10 months to 8 years post-TBI...
December 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27989012/photobiomodulation-reduces-drusen-volume-and-improves-visual-acuity-and-contrast-sensitivity-in-dry-age-related-macular-degeneration
#13
Graham F Merry, Marion R Munk, Robert S Dotson, Michael G Walker, Robert G Devenyi
PURPOSE: To evaluate the efficacy of photobiomodulation (PBM) treatment for patients with dry age-related macular degeneration (AMD). METHODS: Assessments on 42 eyes with dry AMD (age related eye disease study (AREDS) 2-4) were conducted. Multiwavelength light emitting diode (LED) light comprising of yellow (590 nm), red (670 nm) and near-infrared (790 nm) bandwidths was applied to subjects' eyes for a treatment course of 3 weeks. Outcome measures were changes in best-corrected visual acuity (BCVA), contrast sensitivity (CS), drusen volume and central drusen thickness...
December 18, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27988865/photobiomodulation-therapy-management-of-mucosal-necrosis-of-the-oropharynx-in-previously-treated-head-and-neck-cancer-patients
#14
Joel B Epstein, Paul Y Song, Allen S Ho, Babak Larian, Arash Asher, Rene-Jean Bensadoun
Necrosis of the oral mucosa following head and neck cancer radiation therapy presents considerable clinical management challenges. We report three cases of symptomatic persisting oral ulcerations where the addition of photobiomodulation therapy resulted in a rapid resolution of the oral lesions and in patient symptoms. These cases suggest that photobiomodulation may represent an adjunct to care of these difficult to manage complications in oncology.
December 17, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27973730/photobiomodulation-or-low-level-laser-therapy
#15
Michael R Hamblin
No abstract text is available yet for this article.
December 2016: Journal of Biophotonics
https://www.readbyqxmd.com/read/27957350/laser-photobiomodulation-for-a-complex-patient-with-severe-hydroxyurea-induced-oral-ulcerations
#16
Marco Cabras, Adriana Cafaro, Alessio Gambino, Roberto Broccoletti, Ercole Romagnoli, Davide Marina, Paolo G Arduino
Patients affected by polycythemia vera (PV), a myeloproliferative neoplasm characterized by an elevated red blood cell mass, are at high risk of vascular and thrombotic complications. Conventional therapeutic options aim at reducing vascular and thrombotic risk; low-dose aspirin and phlebotomy are first-line recommendations, for patients at low risk of thrombotic events, whereas cytoreductive therapy, usually hydroxyurea (HU) or interferon alpha, is recommended for high-risk patients. In the present study, we report the case of a patient with persistent oral ulcerations, possibly related to long-lasting HU treatment, firstly treated with topic and systemic corticosteroids and then more effectively with the addition of low-level laser therapy...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27943458/non-invasive-red-and-near-infrared-wavelength-induced-photobiomodulation-promoting-impaired-cutaneous-wound-healing
#17
REVIEW
Anju Yadav, Asheesh Gupta
The innumerable intricacies associated with chronic wounds have made the development of new painless, non-invasive, biophysical therapeutic interventions as the focus of current biomedical research. Red and near-infrared light-induced photobiomodulation therapy appears to emerge as a promising drug-free approach for promoting wound healing, reduction of inflammation, pain and restoration of function owing to penetration power in conjunction with their ability to positively modulate the biochemical and molecular responses...
December 10, 2016: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/27943450/photobiomodulation-therapy-in-breast-cancer-related-lymphedema-a-randomized-placebo-controlled-trial
#18
Maximilian Andreas Storz, Benjamin Gronwald, Sven Gottschling, Jakob Schöpe, Russalina Mavrova, Sascha Baum
BACKGROUND: The aim of our study was to examine the effects of Photobiomodulation Therapy (PBMT) in the treatment of breast cancer-related lymphedema using a compactly designed treatment regime consisting of eight therapy sessions in combination with a cluster laser device covering a total area size of 78.54 cm² over the axillary. METHODS: 40 patients with unilateral lymphedema were enrolled in this double blind, placebo-controlled trial in order to evaluate effects of PBMT on lymphedema-related pain, quality of life, grip strength and limb volume difference...
December 10, 2016: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/27927605/in-vivo-experimental-model-of-orthotopic-dental-pulp-regeneration-under-the-influence-of-photobiomodulation-therapy
#19
Maria Stella Moreira, Ivana Marcia Diniz, Maria Fernanda Setúbal Destro Rodrigues, Rejane Andrade de Carvalho, Fernanda Campos de Almeida Carrer, Itamara Itagiba Neves, Giulio Gavini, Márcia Martins Marques
No abstract text is available yet for this article.
January 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27925504/laser-photobiomodulation-in-neuroscience-from-bench-to-bedside
#20
Shimon Rochkind
No abstract text is available yet for this article.
December 2016: Photomedicine and Laser Surgery
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