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Photobiomodulation

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https://www.readbyqxmd.com/read/28712048/photobiomodulation-therapy-improves-both-inflammatory-and-fibrotic-parameters-in-experimental-model-of-lung-fibrosis-in-mice
#1
Robson Alexandre Brochetti, Mayara Peres Leal, Raíssa Rodrigues, Renata Kelly da Palma, Luis Vicente Franco de Oliveira, Anna Carolina Ratto Tempestini Horliana, Amílcar Sabino Damazo, Ana Paula Ligeiro de Oliveira, Rodolfo Paula Vieira, Adriana Lino-Dos-Santos-Franco
Lung fibrosis (LF) is a chronic and progressive lung disease characterized by pulmonary parenchyma progressive lesion, inflammatory infiltration, and interstitial fibrosis. It is developed by excessive collagen deposition and other cellular matrix components, resulting in severe changes in the alveolar architecture. Considering the absence of effective treatment, the aim of this study was to investigate the effect of photobiomodulation therapy (PBMT) on the development of PF. For this purpose, we used C57BL6 mice subjected to induction of LF by bleomycin administration (1...
July 16, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28708285/various-led-wavelengths-affected-myofiber-development-and-satellite-cell-proliferation-of-chick-embryos-via-the-igf-1-signaling-pathway
#2
Yao Wang, Xinjie Bai, Zixu Wang, Jing Cao, Yulan Dong, Yanjun Dong, Yaoxing Chen
An effect of monochromatic light illumination on muscle mass has been discovered in chickens; however, its effect on the development of embryonic muscle remains unclear. Our previous studies demonstrated that monochromatic green light promoted satellite cell proliferation and muscle growth in post-hatching broilers. In this study, we investigated the effects and mechanisms of monochromatic light exposure on muscle development in late-embryogenesis. Seven hundred and fifty (750) fertile broiler eggs were randomly assigned to blue (B-group), green (G-group), red (R-group), white (W-group) lights or darkness (D-group) throughout the incubation period...
July 14, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28702985/photobiomodulation-with-polarized-light-in-the-treatment-of-cutaneous-and-mucosal-ulcerative-lesions
#3
S E Aragona, F R Grassi, G Nardi, J Lotti, G Mereghetti, E Canavesi, E Equizi, A M Puccio, G Gianazza, T Lotti, I Morisi
In recent decades, regenerative medicine has achieved an important evolution at both a conceptual level and scientific production, which explains the current and future possibilities of therapy and daily clinical practice. The main aim of regenerative medicine is the complex system of repair/regeneration. The current literature on the subject demonstrates the advantage of visible light therapy for skin injuries and diseases with the photobiomodulation in which light at low energy levels modulates intra- and extra-cellular photoreceptors by molecular and cellular processes that can stimulate both anti-inflammatory mechanisms and cell proliferative response...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28702983/photobiomodulation-in-the-treatment-of-chronic-non-responding-wounds
#4
S E Aragona, G Mereghetti, G Gianazza, E Equizi, J Lotti, T Lotti, G V L Colombo
We present a protocol of care and therapeutic approach to skin lesions, called AIMED (Anti Inflammatory Regenerative Medicine), which is based on the circularity of its phases and applied therapeutic methodologies. We used photobiomodulation (PBM) for the examination non-responding skin lesions. PBM is an adjuvant treatment for the stimulation of regenerative cellular processes, reduction of inflammation and pain and biochemical modulation of molecular response. We used PBM for the examination of skin lesions, which were not responding to other therapies...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28681084/photobiomodulation-therapy-action-in-wound-repair-skin-induced-in-aged-rats-old-time-course-of-biomarkers-inflammatory-and-repair
#5
Franciane Barbieri Fiorio, Solange Almeida Dos Santos, Caroline Sobral de Melo Rambo, Camila Guerra Dalbosco, Andrey Jorge Serra, Brunno Lemes de Melo, Ernesto Cesar Pinto Leal-Junior, Paulo de Tarso Camillo de Carvalho
Previous studies have discussed an inverse correlation between age and wound healing, because it relates to the association of aging with a gradual decrease in healing capacity. Treatment with photobiomodulation therapy (PBMT) improves wound healing by inducing increases in mitotic activity, numbers of fibroblasts, collagen synthesis, and neovascularization. Therefore, this study aimed to evaluate the effects of PBMT in cutaneous wound healing in aged rats. A punch biopsy of 8 mm in diameter was performed to produce a skin wound...
July 5, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28674791/effects-of-the-gaalas-diode-laser-780%C3%A2-nm-on-the-periodontal-tissues-during-orthodontic-tooth-movement-in-diabetes-rats-histomorphological-and-immunohistochemical-analysis
#6
Mônica Fernandes Gomes, Maria da Graças Vilela Goulart, Lilian Chrystiane Giannasi, Cybelle Mori Hiraoka, Gabriela de Fátima Santana Melo, Aretha Graziela Vilela de Sousa, Celestino José Prudente Nóbrega, Renato Amaro Zangaro, Miguel Angel Castillo Salgado
The purposes of the present study are to assess the effects of the GaAlAs diode laser on the periodontal tissues and to investigate its action on the alveolar bone remodeling process during orthodontic tooth movement in normoglycemic and diabetic rats. Sixty adult male Wistar rats were divided into four groups of 15 rats: normoglycemic (N), diabetic (D), laser-normoglycemic (LN), and laser-diabetic (LD) rats. Diabetes mellitus was induced by a single intravenous injection of 40 mg/kg monohydrated alloxan. The orthodontically moved tooth underwent a force magnitude of 20 cN...
July 3, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28671718/antinociceptive-effects-of-low-level-laser-therapy-at-3-and-8%C3%A2-j-cm-2-in-a-rat-model-of-postoperative-pain-possible-role-of-endogenous-opioids
#7
Fabio C Pereira, Julia R Parisi, Caio B Maglioni, Gabriel B Machado, Paulino Barragán-Iglesias, Josie R T Silva, Marcelo L Silva
Low-level laser therapy (LLLT) is the direct application of light to stimulate cell responses (photobiomodulation) to promote tissue healing, reduce inflammation, and induce analgesia; the molecular basis for these effects of LLLT remains unclear. The objective of this study was to evaluate the analgesic effect of LLLT in the rat plantar incision model of postoperative pain as well as to investigate some of the possible mechanisms involved in this effect. Wistar rats were submitted to plantar incision and treated with LLLT (830 nm, continuous-mode, 30 mW/cm(2) , 1-12 J/cm(2) )...
July 3, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28664388/effect-of-photobiomodulation-therapy-on-reducing-the-chemo-induced-oral-mucositis-severity-and-on-salivary-levels-of-cxcl8-interleukin-8-nitrite-and-myeloperoxidase-in-patients-undergoing-hematopoietic-stem-cell-transplantation-a-randomized-clinical-trial
#8
Daniella Ribeiro Naves Salvador, Danilo Figueiredo Soave, Nancy Tomoko Sacono, Eduardo Fernandes de Castro, Geisa Badauy Lauria Silva, Larissa Pereira E Silva, Tarcília Aparecida Silva, Marize Campos Valadares, Elismauro Francisco Mendonça, Aline Carvalho Batista
Oral mucositis (OM) is the most common debilitating complication among patients undergoing hematopoietic stem cell transplantation (HSCT). Photobiomodulation therapy (PBM) has shown beneficial effects in the treatment of OM, but few studies have evaluated its biological effects. This study evaluated the effect of PBM on the reduction of OM severity in patients undergoing HSCT and its relation to the modulation of the inflammatory response. Fifty-one patients were randomly assigned to two groups: PBM [submitted to PBM from admission (AD) to D+7] (n = 27) and control (n = 24) [received oral hygiene]...
June 29, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28663851/scattering-and-absorption-control-in-biocompatible-fibers-towards-equalized-photobiomodulation
#9
J George, H Haghshenas, D d'Hemecourt, W Zhu, L Zhang, V Sorger
Transparent tissue scaffolds enable illumination of growing tissue to accelerate cell proliferation and improve other cell functions through photobiomodulation. The biphasic dose response of cells exposed to photobiomodulating light dictates that the illumination be evenly distributed across the scaffold such that the cells are neither under nor over exposed to light. However, equalized illumination has not been sufficiently addressed. Here we analyze and experimentally demonstrate spatially equalizing illumination by three methods, namely: engineered surface scattering, reflection by a gold mirror, and traveling-waves in a ring mesh...
March 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28653884/photobiomodulation-of-breast-and-cervical-cancer-stem-cells-using-low-intensity-laser-irradiation
#10
N E Kiro, M R Hamblin, H Abrahamse
Breast and cervical cancers are dangerous threats with regard to the health of women. The two malignancies have reached the highest record in terms of cancer-related deaths among women worldwide. Despite the use of novel strategies with the aim to treat and cure advanced stages of cancer, post-therapeutic relapse believed to be caused by cancer stem cells is one of the challenges encountered during tumor therapy. Therefore, further attention should be paid to cancer stem cells when developing novel anti-tumor therapeutic approaches...
June 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28653257/human-adipose-derived-stem-cell-spheroid-treated-with-photobiomodulation-irradiation-accelerates-tissue-regeneration-in-mouse-model-of-skin-flap-ischemia
#11
In-Su Park, Phil-Sang Chung, Jin Chul Ahn, Anais Leproux
Skin flap grafting is a form of transplantation widely used in plastic surgery. However, ischemia/reperfusion injury is the main factor which reduces the survival rate of flaps following grafting. We investigated whether photobiomodulation (PBM) precondition prior to human adipose-derived stromal cell (hASC) spheroid (PBM-spheroid) transplantation improved skin tissue functional recovery by the stimulation of angiogenesis and tissue regeneration in skin flap of mice. The LED had an emission wavelength peaked at 660 ± 20 nm (6 J/cm(2), 10 mW/cm(2))...
June 27, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28646819/invisalign-with-photobiomodulation-optimizing-tooth-movement-and-treatment-efficacy-with-a-novel-self-assessment-algorithm
#12
Todd E Dickerson
No abstract text is available yet for this article.
March 2017: Journal of Clinical Orthodontics: JCO
https://www.readbyqxmd.com/read/28628423/current-considerations-for-low-level-laser-therapy-photobiomodulation-therapy-in-the-management-of-side-effects-of-chemoradiation-therapy-for-cancer
#13
Kenji Yoshida
No abstract text is available yet for this article.
June 19, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28612300/effects-of-photobiomodulation-therapy-on-bothrops-moojeni-snake-envenomed-gastrocnemius-of-mice-using-enzymatic-biomarkers
#14
Doroty Mesquita Dourado, Rosemary Matias, Marcos Barbosa-Ferreira, Baldomero Antonio Kato da Silva, Jéssica de Araujo Isaias Muller, Willians Fernando Vieira, Maria Alice da Cruz-Höfling
Bothropic venom contains a range of biologically active substances capable of causing severe local and systemic envenoming symptomatology within its victims. The snake anti-venom is effective against systemic effects but has no neutralizing effect against the fast developing local effects. Herein, mice gastrocnemius injected with Bothrops moojeni venom (40 μg/kg) or saline solution were irradiated with HeNe (632.8 nm) and GaAs (904 nm) lasers (daily energy density of 4 J/cm(2); 0.03/0.21 power density; 0...
June 13, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28593105/photobiomodulation-with-near-infrared-light-helmet-in-a-pilot-placebo-controlled-clinical-trial-in-dementia-patients-testing-memory-and-cognition
#15
Marvin H Berman, James P Halper, Trent W Nichols, H Jarrett, Alan Lundy, Jason H Huang
Alzheimer's disease (AD) is a common, chronic expensive debilitating neurodegenerative disease with no current treatments to prevent the physical deterioration of the brain and the consequent cognitive deficits. The current pathophysiology of Alzheimer's disease is the accumulation of neurofibrillary tangles (NFTs) of hyperphosphorylated tau protein and amyloid-beta (Aβ) plaques. Antibody therapy of Tau and Amyloid beta, vaccines and other methods to decrease Tau and or Amyloid have not been successful after considerable pharmaceutical and biotech efforts...
2017: Journal of neurology and neuroscience
https://www.readbyqxmd.com/read/28584230/photobiomodulation-of-human-dermal-fibroblasts-in-vitro-decisive-role-of-cell-culture-conditions-and-treatment-protocols-on-experimental-outcome
#16
C Mignon, N E Uzunbajakava, B Raafs, N V Botchkareva, D J Tobin
Photobiomodulation-based (LLLT) therapies show tantalizing promise for treatment of skin diseases. Confidence in this approach is blighted however by lamentable inconsistency in published experimental designs, and so complicates interpretation. Here we interrogate the appropriateness of a range of previously-reported treatment parameters, including light wavelength, irradiance and radiant exposure, as well as cell culture conditions (e.g., serum concentration, cell confluency, medium refreshment, direct/indirect treatment, oxygen concentration, etc...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28580093/photobiomodulation-and-the-brain-a-new-paradigm
#17
Madison Hennessy, Michael R Hamblin
Transcranial photobiomodulation (PBM) also known as low level laser therapy (tLLLT) relies on the use of red/NIR light to stimulate, preserve and regenerate cells and tissues. The mechanism of action involves photon absorption in the mitochondria (cytochrome c oxidase), and ion channels in cells leading to activation of signaling pathways, up-regulation of transcription factors, and increased expression of protective genes. We have studied PBM for treating traumatic brain injury (TBI) in mice using a NIR laser spot delivered to the head...
January 2017: Journal of Optics
https://www.readbyqxmd.com/read/28557664/efficacy-of-laser-photobiomodulation-on-morphological-and-functional-repair-of-the-facial-nerve
#18
Daniela Vieira Buchaim, Jesus Carlos Andreo, Rui Seabra Ferreira Junior, Benedito Barraviera, Antonio de Castro Rodrigues, Mariana de Cássia Macedo, Geraldo Marco Rosa Junior, Andre Luis Shinohara, Iris Jasmin Santos German, Karina Torres Pomini, Rogerio Leone Buchaim
OBJECTIVE: Evaluate the efficacy of low-level laser therapy (LLLT) on qualitative, quantitative, and functional aspects in the facial nerve regeneration process. MATERIALS AND METHODS: Forty-two male Wistar rats were used, randomly divided into a control group (CG; n = 10), in which the facial nerve without lesion was collected, and four experimental groups: (1) suture experimental group (SEG) and (2) fibrin experimental group (FEG), consisting of 16 animals in which the buccal branch of the facial nerve was sectioned on both sides of the face; an end-to-end epineural suture was performed on the right side, and a fibrin sealant was used on the left side for coaptation of the stumps; and (3) laser suture experimental group (LSEG) and (4) laser fibrin experimental group (LFEG), consisting of 16 animals that underwent the same surgical procedures as SEG and FEG with the addition of laser application at three different points along the surgical site (pulsed laser of 830 nm wavelength, optical output power of 30 mW, power density of 0...
May 26, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28552720/remote-tissue-conditioning-an-emerging-approach-for-inducing-body-wide-protection-against-diseases-of-ageing
#19
REVIEW
Boaz Kim, Alice Brandli, John Mitrofanis, Jonathan Stone, Sivaraman Purushothuman, Daniel M Johnstone
We have long accepted that exercise is 'good for us'; that - put more rigorously - moderate exercise is associated with not just aerobic fitness but also reduced morbidity and reduced mortality from cardiovascular disease and even malignancies. Caloric restriction (moderate hunger) and our exposure to dietary phytochemicals are also emerging as stresses which are 'good for us' in the same sense. This review focuses on an important extension of this concept: that stress localized within the body (e.g. in a limb) can induce resilience in tissues throughout the body...
August 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28549319/effect-of-laser-photobiomodulation-on-wound-healing-and-postoperative-pain-following-free-gingival-graft-a-split-mouth-triple-blind-randomized-controlled-clinical-trial
#20
Mohadeseh Heidari, Mojgan Paknejad, Raika Jamali, Hanieh Nokhbatolfoghahaei, Reza Fekrazad, Neda Moslemi
BACKGROUND AND AIM: Free gingival graft (FGG) is one of the most predictable techniques for gingival augmentation. However, patient's discomfort and pain during healing period are significant concerns. The aim of this study was to assess if laser photobiomodulation (PBM) was effective in terms of enhancing wound healing and reducing postoperative pain. METHODS AND MATERIALS: Twelve patients participated in this split-mouth randomized controlled clinical trial. Each patient had a 30-day interval between the two procedures...
July 2017: Journal of Photochemistry and Photobiology. B, Biology
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