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Photobiomodulation

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https://www.readbyqxmd.com/read/29777942/photomodulation-multiple-sessions-as-a-promising-preventive-therapy-for-medication-related-osteonecrosis-of-the-jaws-after-tooth-extraction-in-rats
#1
Cristian Statkievicz, Luan Felipe Toro, João Martins de Mello-Neto, Daniela Pereira de Sá, Cláudio Aparecido Casatti, João Paulo Mardegan Issa, Luciano Tavares Angelo Cintra, Juliano Milanezi de Almeida, Maria José Hitomi Nagata, Valdir Gouveia Garcia, Leticia Helena Theodoro, Edilson Ervolino
The aim of this study was to evaluate the effects of photobiomodulation (PBM) with multiple sessions of low-level laser on the alveolar repair process of rats with major risk factors for medication-related osteonecrosis of the jaws (MRONJ). Senile rats received 0.45 mL of vehicle (VEH and VEH-PBM) or 0.45 mL of 100 μg/kg zoledronate (ZOL and ZOL-PBM) administrated intraperitoneally every two days during seven weeks. After three weeks of initiation of drug treatment the first lower left molar was extracted...
May 9, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29775553/influence-of-photobiomodulation-therapy-on-gingivitis-induced-by-multi-bracket-appliances-a-split-mouth-randomized-controlled-trial
#2
Steffen Stein, Michael Schauseil, Andreas Hellak, Heike Korbmacher-Steiner, Andreas Braun
OBJECTIVE: The objective of this split-mouth trial was to investigate the influence of photobiomodulation therapy (PBMT) on adjuvant treatment of gingivitis induced by multi-bracket appliances, after bracket debonding and professional tooth cleaning. MATERIALS AND METHODS: Thirteen patients (mean age 16.15 years; standard deviation ±2.12 years) who had completed active orthodontic treatment with fixed orthodontic appliances in an orthodontic clinic were included on a randomized basis...
May 18, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29749025/photobiomodulation-induces-antinociception-recovers-structural-aspects-and-regulates-mitochondrial-homeostasis-in-peripheral-nerve-of-diabetic-mice
#3
Victória Regina da Silva de Oliveira, Diego Pulzatto Cury, Laura Basílio Yamashita, Marcos Vinicius Esteca, Ii-Sei Watanabe, Yoko Fee Bergmann, Elaine Flamia Toniolo, Camila Squarzoni Dale
Diabetic Peripheral Neuropathy (DPN) is a nervous disorder caused by diabetes mellitus, affecting about 50% of patients in clinical medicine. Chronic pain is one of the major and most unpleasant symptoms developed by those patients, and conventional available treatments for the neuropathy, including the associated pain, are still unsatisfactory and benefit only a small number of patients. Photobiomodulation (PBM) has been gaining clinical acceptance once it is able to promote early nerve regeneration resulting in significant improvement peripheral nerves disabilities...
May 11, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29744863/photobiomodulation-therapy-and-vitamin-c-on-longevity-of-cell-sheets-of-human-dental-pulp-stem-cells
#4
Ana C F Pedroni, Ivana M A Diniz, Gabriela L Abe, Maria S Moreira, Carla R Sipert, Márcia M Marques
Photobiomodulation therapy (PBMT) can improve processes relevant to tissue regeneration, such as survival, proliferation, migration, and differentiation of cells, including stem cells. Thus, PBMT could be applied as auxiliary therapy for tissue regeneration. Cell sheets (CSs) induced by vitamin C (VC) can generate large amount of cells, which would also be useful for tissue regeneration. VC and PBMT cause opposite effects on cell metabolism (e.g., VC is antioxidative, and PBMT generates reactive oxygen species); however, hDPSC CSs were formed when VC and PBMT+VC were applied...
May 10, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29744752/indocyanine-green-mediated-photobiomodulation-on-human-osteoblast-cells
#5
Gamze Bölükbaşı Ateş, Ayşe Ak, Bora Garipcan, Murat Gülsoy
Photobiomodulation (PBM) and photodynamic therapy (PDT) share similar mechanisms but have opposite aims. Increased levels of reactive oxygen species (ROS) in the target tissue in response to light combined photosensitizer (PS) application may lead to cell proliferation or oxidative damage depending on the ROS amount. The purpose of the present study is to investigate the effect of indocyanine green (ICG)-mediated PBM on osteoblast cells by measuring cell viability, proliferation, alkaline phosphatase (ALP) activity, mineralization, and gene expressions of three phenotypic osteoblast markers...
May 9, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29742699/effect-of-photobiomodulation-treatment-in-the-sublingual-radial-artery-region-and-along-the-spinal-column-in-individuals-with-multiple-sclerosis-protocol-for-a-randomized-controlled-double-blind-clinical-trial
#6
RANDOMIZED CONTROLLED TRIAL
Tamiris da Silva, Fernanda Cordeiro da Silva, Andréa Oliver Gomes, Ariane Oliveira Viana, Marcela Letícia Leal Gonçalves, Maria Fernanda Setúbal Destro Rodrigues, Anna Carolina Ratto Tempestini Horliana, Daniela de Fátima Teixeira da Silva, Maria Cristina Chavantes, Yara Dadalti Fragoso, Luciana Prats Branco, Lara Jansiski Motta, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Sandra Kalil Bussadori
BACKGROUND: Multiple sclerosis (MS) is an autoimmune disease, for which the forms of treatment are medication and rehabilitation. However, in vitro and in vivo studies have demonstrated that photobiomodulation can be an effective treatment modality for inflammatory diseases, including MS. Photobiomodulation has a broad range of benefits, such as the avoidance of cell and tissue death, the stimulation of healing and injury repair, reductions in pain, edema and inflammation, cell proliferation, and even apoptosis...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29742256/evaluation-of-photobiomodulation-therapy-associated-with-guided-bone-regeneration-in-critical-size-defects-in-vivo-study
#7
Nicole Rosa de Freitas, Luísa Belluco Guerrini, Luis Augusto Esper, Michyele Cristhiane Sbrana, Gisele da Silva Dalben, Simone Soares, Ana Lúcia Pompéia Fraga de Almeida
The repair of bone defects raises the interest of investigators in several health specialties. Grafting techniques with bone substitutes and laser therapies have been investigated to replace autogenous bone and accelerate the bone healing process. Objective To evaluate the effect of photobiomodulation therapy (PBMT) associated with guided bone regeneration (GBR) in critical size defects. Material and Methods The study was conducted on 80 male rats (Rattus norvegicus albinus, Wistar) submitted to surgical creation of a critical size defect on the calvaria, divided into eight study groups: group C (control - only blood clot); group M (collagen membrane); group PBMT (photobiomodulation therapy); group AB (autogenous bone); group AB+PBMT; group AB+M; group PBMT+M; group AB+PBMT+M...
2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29733117/incorporation-of-photobiomodulation-therapy-into-a-therapeutic-exercise-program-for-knee-osteoarthritis-a-placebo-controlled-randomized-clinical-trial
#8
Cid A F de Paula Gomes, Ernesto C P Leal-Junior, Almir V Dibai-Filho, Adriano R de Oliveira, André S Bley, Daniela A Biasotto-Gonzalez, Paulo de Tarso Camillo de Carvalho
OBJECTIVE: To investigate the clinical effects of incorporation of phototherapy in a therapeutic exercise program for individuals with knee osteoarthritis (OA) when compared to a group that received exercise alone and to a group that received exercise + placebo phototherapy. MATERIALS AND METHODS: This is a randomized, blinded and placebo-controlled trial. Thus, sixty male and female individuals aged 40-80 years with knee pain in the previous 6 months participated of the study, with diagnosis of unilateral knee OA based on the criteria established by the American College of Rheumatology and radiographic confirmation and Grades 2 or 3 of the Kellgren-Lawrence Classification...
May 7, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29731669/transcranial-light-emitting-diode-therapy-for-neuropsychological-improvement-after-traumatic-brain-injury-a-new-perspective-for-diffuse-axonal-lesion-management
#9
REVIEW
João Gustavo Rocha Peixoto Dos Santos, Wellingson Silva Paiva, Manoel Jacobsen Teixeira
The cost of traumatic brain injury (TBI) for public health policies is undeniable today. Even patients who suffer from mild TBI may persist with cognitive symptoms weeks after the accident. Most of them show no lesion in computed tomography or conventional magnetic resonance imaging, but microstructural white matter abnormalities (diffuse axonal lesion) can be found in diffusion tensor imaging. Different brain networks work together to form an important part of the cognition process, and they can be affected by TBI...
2018: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29730613/photomodulation-in-the-treatment-of-chronic-pain-in-patients-with-temporomandibular-disorder-protocol-for-cost-effectiveness-analysis
#10
Ana Paula Taboada Sobral, Camila Leal H de Godoy, Kristianne P Santos Fernandes, Sandra Kalil Bussadori, Raquel Agnelli Mesquita Ferrari, Anna Carolina Ratto Tempestini Horliana, Sonia F Monken, Lara J Motta
INTRODUCTION: Epidemiological data show that the signs and symptoms of temporomandibular disorder (TMD) start becoming apparent from 6 years of age, and during adolescence these signs and symptoms are similar to those of adults. The present study aims to estimate the direct costs for treatment of chronic muscle pain with photobiomodulation therapy, occlusal splint and placebo in patients with TMD; to evaluate the effectiveness of photobiomodulation therapy and occlusal splint for treatment of muscle pain in patients with TMD; to analyse the cost-effectiveness of the two proposed treatments for pain; and to describe and compare the results of the analyses of these treatments...
May 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/29728942/evaluation-of-bone-repair-after-application-of-a-norbixin-membrane-scaffold-with-and-without-laser-photobiomodulation-%C3%AE-780-nm
#11
Adrielle Martins Monteiro Alves, Lílian Melo de Miranda Fortaleza, Antonio Luiz Martins Maia Filho, Danniel Cabral Leão Ferreira, Charllyton Luis Sena da Costa, Vicente Galber Freitas Viana, José Zilton Lima Verde Santos, Rauirys Alencar de Oliveira, Gustavo Oliveira de Meira Gusmão, Luís Eduardo Silva Soares
Biocompatible membranes are widely used in medicine to stimulate bone repair. Several studies have demonstrated that laser photobiomodulation (PBM) also stimulates osteoblast proliferation and osteogenesis at the fracture site, leading to a greater deposition of bone mass and accelerating the process of bone consolidation. This work assessed the therapeutic effect of 780-nm laser PBM and a polystyrene membrane coated with norbixin and collagen (PSNC) on bone healing in rats with calvarial bone defect. Histological staining, Raman spectroscopy, and scanning electron microscopy (SEM) were used to evaluate the bone repair process...
May 4, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29727048/multicenter-randomized-double-blind-controlled-trial-to-evaluate-the-efficacy-of-laser-therapy-for-the-treatment-of-severe-oral-mucositis-induced-by-chemotherapy-in-children-lampo-rct
#12
Margherita Gobbo, Federico Verzegnassi, Luca Ronfani, Davide Zanon, Fraia Melchionda, Simone Bagattoni, Alessandra Majorana, Elena Bardellini, Rosamaria Mura, Alessandra Piras, Maria Grazia Petris, Maria Livia Mariuzzi, Angelica Barone, Elisabetta Merigo, Nunzia Decembrino, Marina Consuelo Vitale, Massimo Berger, Patrizia Defabianis, Matteo Biasotto, Giulia Ottaviani, Giulio Andrea Zanazzo
OBJECTIVES: To demonstrate the efficacy of laser photobiomodulation (PBM) compared to that of placebo on severe oral mucositis (OM) in pediatric oncology patients. The primary objective was the reduction of OM grade (World Health Organization [WHO] scale) 7 days after starting PBM. Secondary objectives were reduction of pain, analgesic consumption, and incidence of side effects. METHODS: One hundred and one children with WHO grade > 2 chemotherapy-induced OM were enrolled in eight Italian hospitals...
May 4, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29710411/photobiomodulation-with-red-light-emitting-diodes-accelerates-hepatocytes-proliferation-through-reactive-oxygen-species-extracellular-signal-regulated-kinase-pathway
#13
Rui Feng, Yuji Morine, Tetsuya Ikemoto, Satoru Imura, Syuichi Iwahashi, Yu Saito, Mitsuo Shimada
AIM: Cell-based transplantation is an alternate method of liver transplantation to delay the on-set of end-stage liver diseases. For successful treatment, cells need to be expended in vitro expeditiously. However, autogenetic hepatocytes as the ideal cell source for therapy remain quiescence so proliferation is rare. While photobiomodulation therapy (PBT) has been used to stimulate some kinds of cell proliferation, it is unknown if red light emitting diodes (LED) irradiation can promote primary hepatocyte proliferation...
April 30, 2018: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/29696446/photobiomodulation-effects-on-mrna-levels-from-genomic-and-chromosome-stabilization-genes-in-injured-muscle
#14
Larissa Alexsandra da Silva Neto Trajano, Eduardo Tavares Lima Trajano, Luiz Philippe da Silva Sergio, Adilson Fonseca Teixeira, Andre Luiz Mencalha, Ana Carolina Stumbo, Adenilson de Souza da Fonseca
Muscle injuries are the most prevalent type of injury in sports. A great number of athletes have relapsed in muscle injuries not being treated properly. Photobiomodulation therapy is an inexpensive and safe technique with many benefits in muscle injury treatment. However, little has been explored about the infrared laser effects on DNA and telomeres in muscle injuries. Thus, the aim of this study was to evaluate photobiomodulation effects on mRNA relative levels from genes related to telomere and genomic stabilization in injured muscle...
April 26, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29690927/effects-of-transcranial-led-therapy-on-the-cognitive-rehabilitation-for-diffuse-axonal-injury-due-to-severe-acute-traumatic-brain-injury-study-protocol-for-a-randomized-controlled-trial
#15
João Gustavo Rocha Peixoto Dos Santos, Ana Luiza Costa Zaninotto, Renato Amaro Zângaro, Ana Maria Costa Carneiro, Iuri Santana Neville, Almir Ferreira de Andrade, Manoel Jacobsen Teixeira, Wellingson Silva Paiva
BACKGROUND: Photobiomodulation describes the use of red or near-infrared light to stimulate or regenerate tissue. It was discovered that near-infrared wavelengths (800-900 nm) and red (600 nm) light-emitting diodes (LED) are able to penetrate through the scalp and skull and have the potential to improve the subnormal cellular activity of compromised brain tissue. Different experimental and clinical studies were performed to test LED therapy for traumatic brain injury (TBI) with promising results...
April 24, 2018: Trials
https://www.readbyqxmd.com/read/29688791/correction-gross-and-histologic-evaluation-of-effects-of-photobiomodulation-silver-sulfadiazine-and-a-topical-antimicrobial-product-on-experimentally-induced-full-thickness-skin-wounds-in-green-iguanas-iguana-iguana
#16
https://www.readbyqxmd.com/read/29688627/photobiomodulation-of-a-flowable-matrix-in-a-human-skin-ex-vivo-model-demonstrates-energy-based-enhancement-of-engraftment-integration-and-remodeling
#17
Lia Mara Grosso Neves, Nivaldo Antonio Parizotto, Marcia Regina Cominetti, Ardeshir Bayat
The use of dermal substitutes to treat skin defects such as ulcers has shown promising results, suggesting a potential role for skin substitutes for treating acute and chronic wounds. One of the main drawbacks with the use of dermal substitutes is the length of time from engraftment to graft take, plus the risk of contamination and failure due to this prolonged integration. Therefore, the use of adjuvant energy-based therapeutic modalities to augment and accelerate the rate of biointegration by dermal substitute engraftments is a desirable outcome...
April 24, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29684717/photobiomodulation-mechanisms-in-the-kinetics-of-the-wound-healing-process-in-rats
#18
A N Otterço, A L Andrade, P Brassolatti, K N Z Pinto, H S S Araújo, N A Parizotto
OBJECTIVES: The healing process of cutaneous lesions is considered a complex event divided into distinct and overlapping phases, which responds satisfactorily to photobiomodulation (PBM). PBM is indicated as a therapeutic resource capable of assisting tissue repair. The present study aimed to analyze the kinetics of cutaneous wounds healing process after application of the GaAlAs laser for treating wounds on the dorsum of rats. MATERIALS AND METHODS: This study was approved by the Animal Ethics Committee of UFSCar...
April 8, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29681940/variation-of-energy-in-photobiomodulation-for-the-control-of-radiotherapy-induced-oral-mucositis-a-clinical-study-in-head-and-neck-cancer-patients
#19
Cizelene do Carmo Faleiros Veloso Guedes, Silas Antonio Juvencio de Freitas Filho, Paulo Rogério de Faria, Adriano Mota Loyola, Robinson Sabino-Silva, Sérgio Vitorino Cardoso
Oral mucositis (OM) is a frequent and severe adverse effect of therapy against head and neck cancer. Photobiomodulation with the low-power laser is known to be effective against OM, but the diversity of protocols and the possibility of stimulating residual tumor cells are still obstacles. The present study aimed to compare two doses of laser energy delivered to the oral mucosa of patients under oncologic treatment for head and neck cancer, looking for differences in the control of mucositis, as well as in the frequency of tumoral recurrences...
2018: International Journal of Dentistry
https://www.readbyqxmd.com/read/29665018/differential-response-of-human-dermal-fibroblast-subpopulations-to-visible-and-near-infrared-light-potential-of-photobiomodulation-for-addressing-cutaneous-conditions
#20
Charles Mignon, Natallia E Uzunbajakava, Irene Castellano-Pellicena, Natalia V Botchkareva, Desmond J Tobin
BACKGROUND OBJECTIVES: The past decade has witnessed a rapid expansion of photobiomodulation (PBM), demonstrating encouraging results for the treatment of cutaneous disorders. Confidence in this approach, however, is impaired not only by a lack of understanding of the light-triggered molecular cascades but also by the significant inconsistency in published experimental outcomes, design of the studies and applied optical parameters. This study aimed at characterizing the response of human dermal fibroblast subpopulations to visible and near-infrared (NIR) light in an attempt to identify the optical treatment parameters with high potential to address deficits in aging skin and non-healing chronic wounds...
April 17, 2018: Lasers in Surgery and Medicine
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