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Photobiomodulation

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https://www.readbyqxmd.com/read/29349512/photobiomodulation-induces-in-vitro-re-epithelialization-via-nitric-oxide-production
#1
Manuela Rizzi, Mario Migliario, Stelvio Tonello, Vincenzo Rocchetti, Filippo Renò
Photobiomodulation is a widely used tool in regenerative medicine thanks to its ability to modulate a plethora of physiological responses. Wound re-epithelialization is strictly regulated by locally produced chemical mediators, such as nitric oxide (NO), a highly reactive free radical generated by the nitric oxide synthase (NOS) enzymatic family. In this study, it has been hypothesized that a 980-nm low-level laser stimulation could increase NO production in human keratinocytes and that such event might be directly related to the re-epithelialization process...
January 18, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29330655/effectiveness-for-dentin-hypersensitivity-treatment-of-non-carious-cervical-lesions-a-meta-analysis
#2
REVIEW
Vittorio Moraschini, Larissa Salina da Costa, Gustavo Oliveira Dos Santos
OBJECTIVE: The aim of this review is to conduct a systematic review and meta-analysis comparing the effectiveness of in-home or in-office treatments for dentin hypersensitivity. MATERIALS AND METHODS: An electronic search without restriction on dates or languages was performed in four electronic databases until March 2017. In addition, hand-searches in regular journals and in the gray literature were also conducted. To develop the search strategy, clinical questions were formulated using the PICOS method...
January 12, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29327206/brain-photobiomodulation-therapy-a-narrative-review
#3
REVIEW
Farzad Salehpour, Javad Mahmoudi, Farzin Kamari, Saeed Sadigh-Eteghad, Seyed Hossein Rasta, Michael R Hamblin
Brain photobiomodulation (PBM) therapy using red to near-infrared (NIR) light is an innovative treatment for a wide range of neurological and psychological conditions. Red/NIR light is able to stimulate complex IV of the mitochondrial respiratory chain (cytochrome c oxidase) and increase ATP synthesis. Moreover, light absorption by ion channels results in release of Ca2+ and leads to activation of transcription factors and gene expression. Brain PBM therapy enhances the metabolic capacity of neurons and stimulates anti-inflammatory, anti-apoptotic, and antioxidant responses, as well as neurogenesis and synaptogenesis...
January 11, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29310710/photobiomodulation-using-low-level-laser-therapy-lllt-for-patients-with-chronic-traumatic-brain-injury-a-randomized-controlled-trial-study-protocol
#4
Guilherme da Cruz Ribeiro Poiani, Ana Luiza Zaninotto, Ana Maria Costa Carneiro, Renato Amaro Zangaro, Afonso Shiguemi Inoue Salgado, Rodolfo Borges Parreira, Almir Ferreira de Andrade, Manoel Jacobsen Teixeira, Wellingson Silva Paiva
BACKGROUND: Photobiomodulation using low-level laser therapy (LLLT) has been tested as a new technique to optimize recovery of patients with traumatic brain injury (TBI). The aim of this study is to evaluate inhibitory attentional control after 18 sessions of active LLLT and compare with the placebo group (sham LLLT). Our exploratory analysis will evaluate the efficacy of the active LLLT on verbal and visuospatial episodic memory, executive functions (working memory, verbal and visuospatial fluency, attentional processes), and anxiety and depressive symptoms compared to the sham group...
January 8, 2018: Trials
https://www.readbyqxmd.com/read/29307593/transcranial-near-infrared-photobiomodulation-attenuates-memory-impairment-and-hippocampal-oxidative-stress-in-sleep-deprived-mice
#5
Farzad Salehpour, Fereshteh Farajdokht, Marjan Erfani, Saeed Sadigh-Eteghad, Siamak Sandoghchian Shotorbani, Michael R Hamblin, Pouran Karimi, Seyed Hossein Rasta, Javad Mahmoudi
Sleep deprivation (SD) causes oxidative stress in the hippocampus and subsequent memory impairment. In this study, the effect of near-infrared (NIR) photobiomodulation (PBM) on learning and memory impairment induced by acute SD was investigated. The mice were subjected to an acute SD protocol for 72 hr. Simultaneously, NIR PBM using a laser at 810 nm was delivered (once a day for 3 days) transcranially to the head to affect the entire brain of mice. The Barnes maze and the What-Where-Which task were used to assess spatial and episodic-like memories...
January 4, 2018: Brain Research
https://www.readbyqxmd.com/read/29280079/photobiomodulation-increases-mitochondrial-citrate-synthase-activity-in-rats-submitted-to-aerobic-training
#6
Wouber Hérickson de Brito Vieira, Cleber Ferraresi, Maria Luiza Barcellos Schwantes, Sérgio Eduardo de Andrade Perez, Vilmar Baldissera, Mikhail Santos Cerqueira, Nivaldo Antonio Parizotto
This study investigated the effects of photobiomodulation by low-laser laser therapy (LLLT) on the activities of citrate synthase (CS) and lactate dehydrogenase (LDH) and the anaerobic threshold (AT) in rats submitted to treadmill exercise. Fifty-four rats were allocated into four groups: rest control (RCG), rest laser (RLG), exercise control (ECG), and exercise laser (ELG). The infrared LLLT was applied daily on the quadriceps, gluteus maximum, soleus, and tibialis anterior muscles. Muscle samples (soleus, tibialis anterior, and cardiac muscles) were removed 48 h after the last exercise session for spectrophotometric analysis of the CS and LDH...
December 26, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29274167/effects-of-photobiomodulation-on-sofat-a-t-cell-derived-cytokine-may-explain-accelerated-orthodontic-tooth-movement
#7
Viviane Jettar, Marcelo Napimoga, Fabiana Freitas, Juliana Clemente-Napimoga, Selly Suzuki, Victor Montalli, Aguinaldo Garcez
Orthodontic tooth movement is based on mechanical forces inducing bone remodeling and several methods have been proposed to increase tooth movement, including photobiomodulation. This study evaluated, in an animal model, the effects of photobiomodulation on SOFAT - a secreted osteoclastogenic factor of activated T cells and RANK-L during tooth movement. The results showed that tooth displacement, RANK-L and SOFAT levels were significantly greater compared to control group. SOFAT may play an important role in bone remodeling during orthodontic movement, possibly increasing the osteoclast cells at the compression area and bone remodeling activity...
December 23, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29247431/infrared-photobiomodulation-pbm-therapy-improves-glucose-metabolism-and-intracellular-insulin-pathway-in-adipose-tissue-of-high-fat-fed-mice
#8
Gabriela Silva, Cleber Ferraresi, Rodrigo Teixeira de Almeida, Mariana Lopes Motta, Thiago Paixão, Vinicius Oliveira Ottone, Ivana Alice Fonseca, Murilo Xavier Oliveira, Etel Rocha-Vieira, Marco Fabrício Dias-Peixoto, Elizabethe Adriana Esteves, Cândido Celso Coimbra, Fabiano Trigueiro Amorim, Flávio de Castro Magalhães
Obesity represents a continuously growing global epidemic and is associated with the development of type 2 diabetes mellitus. The etiology of type 2 diabetes is related to the resistance of insulin-sensitive tissues to its action leading to impaired blood glucose regulation. Photobiomodulation (PBM) therapy might be a non-pharmacological, non-invasive strategy to improve insulin resistance. It has been reported that PBM therapy in combination with physical exercise reduces insulin resistance. Therefore, the aim of this study was to investigate the effects of PBM therapy on insulin resistance in obese mice...
December 15, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29239111/effect-of-670%C3%A2-nm-laser-photobiomodulation-on-vascular-density-and-fibroplasia-in-late-stages-of-tissue-repair
#9
Tila Fortuna, Ana Cristina Gonzalez, Maíra F Sá, Zilton de A Andrade, Sílvia R A Reis, Alena R A P Medrado
This study aimed to investigate the effects of gallium-aluminum-arsenium (GaAlAs) (670 nm) laser therapy on neoangiogenesis and fibroplasia during tissue remodelling. Forty male Wistar rats underwent cutaneous surgery and were divided into 2 experimental groups: the Control and Laser group (9 mW, 670 nm, 0.031 W/cm2 , 4 J/cm2 ). After 14, 21, 28, and 35 days, the animals were euthanised. Descriptive and quantitative analyses were performed in sections stained with haematoxylin-eosin and Sirius Red, respectively...
December 13, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29227581/aging-of-lymphoid-organs-can-photobiomodulation-reverse-age-associated-thymic-involution-via-stimulation-of-extrapineal-melatonin-synthesis-and-bone-marrow-stem-cells
#10
REVIEW
Denis Odinokov, Michael R Hamblin
Thymic atrophy and the subsequent reduction in T cell production are the most noticeable age-related changes affecting lymphoid organs in the immune system. In fact thymic involution has been described as "programmed aging". New therapeutic approaches such as photobiomodulation (PBM) may reduce or reverse these changes. PBM (also known as low-level laser therapy or LLLT) involves the delivery of non-thermal levels of red or near-infrared light that are absorbed by mitochondrial chromophores, in order to prevent tissue death and stimulate healing and regeneration...
December 11, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29227207/photobiomodulation-how-many-sessions-and-how-often
#11
Jan Tunér
No abstract text is available yet for this article.
December 11, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29216916/low-level-laser-therapy-photobiomodulation-therapy-for-breast-cancer-related-lymphedema-a-systematic-review
#12
G David Baxter, Lizhou Liu, Simone Petrich, Angela Spontelli Gisselman, Cathy Chapple, Juanita J Anders, Steve Tumilty
BACKGROUND: Breast cancer related lymphedema (BCRL) is a prevalent complication secondary to cancer treatments which significantly impacts the physical and psychological health of breast cancer survivors. Previous research shows increasing use of low level laser therapy (LLLT), now commonly referred to as photobiomodulation (PBM) therapy, for BCRL. This systematic review evaluated the effectiveness of LLLT (PBM) in the management of BCRL. METHODS: Clinical trials were searched in PubMed, AMED, Web of Science, and China National Knowledge Infrastructure up to November 2016...
December 7, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29215714/photobiomodulation-of-mesenchymal-stem-cells-encapsulated-in-an-injectable-rhbmp4-loaded-hydrogel-directs-hard-tissue-bioengineering
#13
Ivana Márcia Alves Diniz, Ana Cláudia O Carreira, Carla Renata Sipert, Cindi Mie Uehara, Maria Stella Nunes Moreira, Laila Freire, Cibele Pelissari, Patrícia M Kossugue, Daniele Ribeiro de Araújo, Mari Cleide Sogayar, Márcia Martins Marques
Photobiomodulation (PBM) therapy displays relevant properties for tissue healing and regeneration, which may be of interest for the tissue engineering field. Here, we show that PBM is able to improve cell survival and to interact with recombinant human Bone Morphogenetic Protein 4 (rhBMP4) to direct and accelerate odonto/osteogenic differentiation of dental derived mesenchymal stem cells (MSCs). MSCs were encapsulated in an injectable and thermo-responsive cell carrier (Pluronic® F-127) loaded with rhBMP4 and then photoactivated...
December 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29209866/photobiomodulation-therapy-protects-skeletal-muscle-and-improves-muscular-function-of-mdx-mice-in-a-dose-dependent-manner-through-modulation-of-dystrophin
#14
Gianna Móes Albuquerque-Pontes, Heliodora Leão Casalechi, Shaiane Silva Tomazoni, Andrey Jorge Serra, Cheila de Sousa Bacelar Ferreira, Rodrigo Barbosa de Oliveira Brito, Brunno Lemes de Melo, Adriane Aver Vanin, Kadma Karênina Damasceno Soares Monteiro, Humberto Dellê, Lucio Frigo, Rodrigo Labat Marcos, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior
This study aimed to analyze the protective effects of photobiomodulation therapy (PBMT) with combination of low-level laser therapy (LLLT) and light emitting diode therapy (LEDT) on skeletal muscle tissue to delay dystrophy progression in mdx mice (DMD mdx ). To this aim, mice were randomly divided into five different experimental groups: wild type (WT), placebo-control (DMD mdx ), PBMT with doses of 1 J (DMD mdx ), 3 J (DMD mdx ), and 10 J (DMD mdx ). PBMT was performed employing a cluster probe with 9 diodes (1 x 905nm super-pulsed laser diode; 4 x 875nm infrared LEDs; and 4 x 640nm red LEDs, manufactured by Multi Radiance Medical®, Solon - OH, USA), 3 times a week for 14 weeks...
December 5, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29205705/retinal-pigment-epithelium-in-the-pathogenesis-of-age-related-macular-degeneration-and-photobiomodulation-as-a-potential-therapy
#15
REVIEW
Jack Ao, John Pm Wood, Glyn Chidlow, Mark C Gillies, Robert J Casson
The retinal pigment epithelium (RPE) comprises a monolayer of cells located between the neuroretina and the choriocapillaries. The RPE serves several important functions in the eye: formation of the blood retinal barrier, protection of the retina from oxidative stress, nutrient delivery and waste disposal, ionic homeostasis, phagocytosis of photoreceptor outer segments, synthesis and release of growth factors, reisomerization of all-trans-retinal during the visual cycle, and establishment of ocular immune privilege...
December 5, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/29204915/is-photobiomodulation-pbm-effective-for-the-treatment-of-dentin-hypersensitivity-a-systematic-review
#16
Alana Cristina Machado, Ítallo Emídio Lira Viana, Aloisio Melo Farias-Neto, Mariana Minatel Braga, Carlos de Paula Eduardo, Patricia Moreira de Freitas, Ana Cecilia Corrêa Aranha
The present study aims to evaluate the current scientific data regarding the effectiveness of photobiomodulation (PBM) in the treatment of dentin hypersensitivity (DH) as an alternative method for pain control. A systematic review was conducted to assess the effectiveness of PBM as treatment for DH. A complete literature search was performed up to October 2016. Searches were conducted using Boolean operators and MeSH terms. References of all selected full-text articles and related reviews were scanned. A total of 280 articles were identified (241 articles were excluded by the title and abstract)...
December 5, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29199384/low-intensity-led-therapy-658%C3%A2-nm-on-burn-healing-a-series-of-cases
#17
Rauirys Alencar de Oliveira, Luara Lis Barbosa Boson, Seísa Marina Martins Portela, Antônio Luiz Martins Maia Filho, Denyberg de Oliveira Santiago
The objective of this study was to evaluate the effects of LED on burns healing. Five patients with skin burns were submitted to photobiomodulation by LED, GaAsIP diode, (λ 658 nm) with 40 mW, 7 J/cm2 on every other day. Biopsies of burned skin were performed and the healing process was photographed. Patients with bilateral burns were used as self-control, having one limb being irradiated and the contralateral limb irradiated with placebo. The burns treated with LED showed higher epithelization, with keratinocytes and fibroblasts proliferation, increased collagen synthesis, decreased pain, and pruritus...
December 4, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29196833/chondroitin-sulfate-and-glucosamine-sulfate-associated-to-photobiomodulation-prevents-degenerative-morphological-changes-in-an-experimental-model-of-osteoarthritis-in-rats
#18
Marcella Sanches, Lívia Assis, Cyntia Criniti, Danilo Fernandes, Carla Tim, Ana Claudia Muniz Renno
The aim of this study was to compare the effects of combined treatment with chondroitin sulfate and glucosamine sulfate (CS/Gl) and photobiomodulation (PBM) on the degenerative process related to osteoarthritis (OA) in the articular cartilage in rats. Forty male Wistar rats were randomly divided into four groups: OA control group (CG); OA animals submitted to PBM treatment (PBM); OA animals submitted to CS/Gl treatment (CS/Gl); OA submitted to CS/GS associated with PBM treatments (GS/Gl + PBM). The CS/Gl started 48 h after the surgery, and they were performed for 29 consecutive days...
December 1, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29185134/when-is-the-best-moment-to-apply-photobiomodulation-therapy-pbmt-when-associated-to-a-treadmill-endurance-training-program-a-randomized-triple-blinded-placebo-controlled-clinical-trial
#19
Eduardo Foschini Miranda, Shaiane Silva Tomazoni, Paulo Roberto Vicente de Paiva, Henrique Dantas Pinto, Denis Smith, Larissa Aline Santos, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior
Photobiomodulation therapy (PBMT) employing low-level laser therapy (LLLT) and/or light emitting diode therapy (LEDT) has emerged as an electrophysical intervention that could be associated with aerobic training to enhance beneficial effects of aerobic exercise. However, the best moment to perform irradiation with PBMT in aerobic training has not been elucidated. The aim of this study was to assess the effects of PBMT applied before and/or after each training session and to evaluate outcomes of the endurance-training program associated with PBMT...
November 29, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29181643/vibrational-spectroscopy-of-muscular-tissue-intoxicated-by-snake-venom-and-exposed-to-photobiomodulation-therapy
#20
Willians Fernando Vieira, Bruno Kenzo-Kagawa, Maria Helena Mesquita Britto, Helder José Ceragioli, Kumiko Koibuchi Sakane, Vitor Baranauskas, Maria Alice da Cruz-Höfling
The pathogenesis of myonecrosis caused by myotoxins from bothropic venom is associated with local extracellular matrix (ECM) disintegration, hemorrhage, and inflammation. Search for alternative methods associated with serum therapy is mandatory to neutralize the fast development of local damage following snakebites. The experimental use of photobiomodulation therapy (PBMT) in murine models has shown promising results relative to structural and functional recovery from bothropic snakebite-induced myonecrosis...
November 28, 2017: Lasers in Medical Science
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