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https://www.readbyqxmd.com/read/28809365/type-of-surgical-treatment-and-recurrence-of-oral-leukoplakia-a-retrospective-clinical-study
#1
L Monteiro, C Barbieri, S Warnakulasuriya, M Martins, F Salazar, J-J Pacheco, P Vescovi, M Meleti
BACKGROUND: Oral leukoplakia (OL) is the most typical potentially malignant disorder of the oral mucosa. We aimed to evaluate the clinical outcome of oral leukoplakia treated with several types of lasers and with the use of quantic molecular resonance (QMR) lancet, in terms of recurrence rate. MATERIAL AND METHODS: Eighty-seven previously untreated OL (52 occurring in females and 35 in males, mean age of 59.4 ± 13.9 years) were consecutively submitted to surgical treatment at University Hospital of Parma, Italy, and Hospital de Valongo, Portugal, (1999 to 2012)...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28801884/identification-and-partial-structural-characterization-of-mass-isolated-valsartan-and-its-metabolite-with-messenger-tagging-vibrational-spectroscopy
#2
Olga Gorlova, Sean M Colvin, Antonio Brathwaite, Fabian S Menges, Stephanie M Craig, Scott J Miller, Mark A Johnson
Recent advances in the coupling of vibrational spectroscopy with mass spectrometry create new opportunities for the structural characterization of metabolites with great sensitivity. Previous studies have demonstrated this scheme on 300 K ions using very high power free electron lasers in the fingerprint region of the infrared. Here we extend the scope of this approach to a single investigator scale as well as extend the spectral range to include the OH stretching fundamentals. This is accomplished by detecting the IR absorptions in a linear action regime by photodissociation of weakly bound N2 molecules, which are attached to the target ions in a cryogenically cooled, rf ion trap...
August 11, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28777599/scanning-gate-microscope-for-cold-atomic-gases
#3
Samuel Häusler, Shuta Nakajima, Martin Lebrat, Dominik Husmann, Sebastian Krinner, Tilman Esslinger, Jean-Philippe Brantut
We present a scanning probe microscopy technique for spatially resolving transport in cold atomic gases, in close analogy with scanning gate microscopy in semiconductor physics. The conductance of a quantum point contact connected to two atomic reservoirs is measured in the presence of a tightly focused laser beam acting as a local perturbation that can be precisely positioned in space. By scanning its position and recording the subsequent variations of conductance, we retrieve a high-resolution map of transport through a quantum point contact...
July 21, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28753078/which-is-more-effective-for-pain-relief-during-fractionated-carbon-dioxide-laser-treatment-emla-cream-or-forced-cold-air-anesthesia
#4
Elif Sari, Bulent Bakar
BACKGROUND AND AIM: The aim of this study was to compare the effectiveness of a eutectic mixture of local anesthetic (EMLA) cream and forced cold air anesthesia (FCAA) on pain control during ablative fractionated carbon dioxide (CO2) laser treatment. METHODS: Fifteen volunteers participated in this prospective, controlled, split-face clinical study. EMLA cream was applied 60 minutes before the laser procedure on half of the face, and FCAA was performed on each subunit of the other half of the face...
July 28, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28731766/observing-dissipative-topological-defects-with-coupled-lasers
#5
Vishwa Pal, Chene Tradonsky, Ronen Chriki, Asher A Friesem, Nir Davidson
Topological defects have been observed and studied in a wide range of systems, such as cosmology, spin systems, cold atoms, and optics, as they are quenched across a phase transition into an ordered state. These defects limit the coherence of the system and its ability to approach a fully ordered state, so revealing their origin and control is becoming an increasingly important field of research. We observe dissipative topological defects in a one-dimensional ring of phased-locked lasers, and show how their formation is related to the Kibble-Zurek mechanism and is governed in a universal manner by two competing time scales...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28729391/edward-f-adolph-distinguished-lecture-skin-deep-insights-into-vascular-aging
#6
W Larry Kenney
The skin is an accessible model circulation for studying vascular function and dysfunction across the lifespan. Age-related changes, as well as those associated with disease progression, often appear first in the cutaneous circulation. Further, impaired vascular signaling and attendant endothelial dysfunction -- one of the earliest indicators of cardiovascular pathogenesis -- occurs in a similar fashion across multiple tissue beds throughout the body including the skin. Because microvascular dysfunction is a better predictor of long term outcomes and adverse cardiovascular events than is large vessel disease, understanding age-associated changes in the control of the human cutaneous microcirculation is important...
July 20, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28718950/radiofrequency-ablation-for-the-management-of-thyroid-nodules-a-critical-appraisal-of-the-literature
#7
REVIEW
Roberto Cesareo, Andrea Palermo, Valerio Pasqualini, Roberto Cianni, Gianluigi Gaspa, Silvia Manfrini, Claudio Maurizio Pacella
The majority of benign thyroid nodules are asymptomatic, remain stable in size and do not require treatment. However, a minority of patients with growing nodules may have local symptoms or cosmetic concerns, and thus demand surgical therapy. The timely use of ultrasound-guided, minimally invasive thermal therapies has changed the natural history of benign, enlarging thyroid nodules (TNs). These procedures produce persistent shrinkage of TNs and an improvement of local symptoms. Among the various procedures, percutaneous ethanol injection represents the first-line treatment for thyroid cysts, while in solid cold nodules, laser and radiofrequency ablation (RFA) have proven to be very effective and safe techniques in producing significant volume reduction that remains stable over several years...
July 18, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28712168/justification-for-re-look-cystoscopy-after-posterior-urethral-valve-fulguration
#8
Gul Nawaz, Ijaz Hussain, Shujah Muhammad, Muhammad Imran Jamil, Asad Ur Rehman, Nadeem Iqbal, Saeed Akhter
BACKGROUND: Posterior urethral valve (PUV) is life-threatening congenital anomaly of the urinary tract that results in vesicoureteric reflux, recurrent UTI, voiding dysfunction and renal insufficiency if not treat timely. Endoscopic ablation of posterior urethral valves using cold knife or laser is the current gold standard therapy. Many urologists go for repeat cystoscopy to see residual valve or stricture while others repeat VCUG to measure the posterior to anterior urethral ratio for residual obstruction...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28707949/magnetically-induced-optical-transparency-on-a-forbidden-transition-in-strontium-for-cavity-enhanced-spectroscopy
#9
Matthew N Winchester, Matthew A Norcia, Julia R K Cline, James K Thompson
In this Letter we realize a narrow spectroscopic feature using a technique that we refer to as magnetically induced optical transparency. A cold ensemble of ^{88}Sr atoms interacts with a single mode of a high-finesse optical cavity via the 7.5 kHz linewidth, spin forbidden ^{1}S_{0} to ^{3}P_{1} transition. By applying a magnetic field that shifts two excited state Zeeman levels, we open a transmission window through the cavity where the collective vacuum Rabi splitting due to a single level would create destructive interference for probe transmission...
June 30, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28707920/large-fluctuations-for-spatial-diffusion-of-cold-atoms
#10
Erez Aghion, David A Kessler, Eli Barkai
We use a new approach to study the large fluctuations of a heavy-tailed system, where the standard large-deviations principle does not apply. Large-deviations theory deals with tails of probability distributions and the rare events of random processes, for example, spreading packets of particles. Mathematically, it concerns the exponential falloff of the density of thin-tailed systems. Here we investigate the spatial density P_{t}(x) of laser-cooled atoms, where at intermediate length scales the shape is fat tailed...
June 30, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28707371/individuals-with-sickle-cell-disease-have-a-significantly-greater-vasoconstriction-response-to-thermal-pain-than-controls-and-have-significant-vasoconstriction-in-response-to-anticipation-of-pain
#11
Maha Khaleel, Mammen Puliyel, Payal Shah, John Sunwoo, Roberta M Kato, Patjanaporn Chalacheva, Wanwara Thuptimdang, Jon Detterich, John C Wood, Jennie Tsao, Lonnie Zeltzer, Richard Sposto, Michael C K Khoo, Thomas D Coates
The painful vaso-occlusive crises (VOC) that characterize sickle cell disease (SCD) progress over hours from the asymptomatic steady-state. SCD patients report that VOC can be triggered by stress, cold exposure and pain itself. We anticipated that pain could cause neural-mediated vasoconstriction, decreasing regional blood flow and promoting entrapment of sickle cells in the microvasculature. Therefore, we measured microvascular blood flow in the fingers of both hands using plethysmography and laser-Doppler flowmetry while applying a series of painful thermal stimuli on the right forearm in 23 SCD patients and 25 controls...
July 13, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28704481/renal-auto-transplantation-promotes-cortical-microvascular-network-remodeling-in-a-preclinical-porcine-model
#12
Souleymane Maïga, Geraldine Allain, Thierry Hauet, Jerome Roumy, Edouard Baulier, Michel Scepi, Manuel Dierick, Luc Van Hoorebeke, Patrick Hannaert, Franck Guy, Frederic Favreau
The vascular network is a major target of ischemia-reperfusion, but has been poorly investigated in renal transplantation. The aim of this study was to characterize the remodeling of the renal vascular network that follows ischemia-reperfusion along with the most highly affected cortex section in a preclinical renal transplantation model. There were two experimental groups. The first was a grafted kidney group consisting of large white pigs for which the left kidney was harvested, cold flushed, preserved for 24 h in the University of Wisconsin's preservation solution, and then auto-transplanted (n = 5); the right kidney was removed to mimic the situation of human kidney transplantation...
2017: PloS One
https://www.readbyqxmd.com/read/28697506/evaluation-of-the-efficacy-and-safety-of-laser-versus-cold-knife-urethrotomy-in-the-management-of-patients-with-urethral-strictures-a-systematic-review-and-meta-analysis-of-randomized-clinical-trials
#13
Lynda Torres Castellanos, María Camila Moreno Bencardino, Alejandra Bravo-Balado, Carlos Andrés García Mayorga, Isis Vargas Manrique, Nicolás Fernández
INTRODUCTION: Urethral strictures generate great morbidity. Two procedures have been described for their management - laser and cold knife techniques - which are still widely used. We aim to assess the safety and efficacy of laser versus cold knife urethrotomy. MATERIALS AND METHODS: We conducted a systematic search of the literature using MEDLINE, EMBASE, LILACS and Cochrane databases and gray literature. Primary outcomes were urethral stricture recurrence, time-to-recurrence and complication rate...
July 12, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28688412/conformation-selective-resonant-photoelectron-imaging-from-dipole-bound-states-of-cold-3-hydroxyphenoxide
#14
Guo-Zhu Zhu, Dao-Ling Huang, Lai-Sheng Wang
We report a photoelectron imaging and photodetachment study of cryogenically cooled 3-hydroxyphenoxide (3HOP) anions, m-HO(C6H4)O(-). In a previous preliminary study, two conformations of the cold 3HOP anions with different dipole bound states were observed [D. L. Huang et al., J. Phys. Chem. Lett. 6, 2153 (2015)]. Five near-threshold vibrational resonances were revealed in the photodetachment spectrum from the dipole-bound excited states of the two conformations. Here, we report a more extensive investigation of the two conformers with observation of thirty above-threshold vibrational resonances in a wide spectral range between 18 850 and 19 920 cm(-1) (∼1000 cm(-1) above the detachment thresholds)...
July 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28684844/distributed-quasi-bragg-beam-splitter-in-crossed-atomic-waveguides
#15
V Guarrera, R Moore, A Bunting, T Vanderbruggen, Y B Ovchinnikov
We perform an experimental and theoretical study of a novel distributed quasi-Bragg splitter for cold atoms propagating in crossed optical waveguides. The atoms are guided by horizontal red-detuned laser beams which cross with an angle of roughly 90°. The lattice formed by the interference between the two waveguides is used as a quasi-Bragg splitter to continuously deflect the atomic flux from one waveguide into the other. In the limit of strong waveguide confinement and depending on the velocity of the cloud, three main regimes are observed corresponding (1) to the absence of reflection, (2) to partial reflection and (3) to full reflection into the second waveguide...
July 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28652494/optical-atomic-phase-reference-and-timing
#16
L Hollberg, E H Cornell, A Abdelrahmann
Atomic clocks based on laser-cooled atoms have made tremendous advances in both accuracy and stability. However, advanced clocks have not found their way into widespread use because there has been little need for such high performance in real-world/commercial applications. The drive in the commercial world favours smaller, lower-power, more robust compact atomic clocks that function well in real-world non-laboratory environments. Although the high-performance atomic frequency references are useful to test Einstein's special relativity more precisely, there are not compelling scientific arguments to expect a breakdown in special relativity...
August 6, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28646238/-bladder-neck-sclerosis-following-prostate-surgery-which-therapy-when
#17
REVIEW
J J Rassweiler, H Weiss, A Heinze, M Elmussareh, M Fiedler, A S Goezen
Secondary bladder neck sclerosis represents one of the more frequent complications following endoscopic, open, and other forms of minimally invasive prostate surgery. Therapeutic decisions depend on the type of previous intervention (e.g., radical prostatectomy, TURP, HoLEP, radiotherapy, HIFU) and on associated complications (e.g., incontinence, fistula). Primary treatment in most cases represents an endoscopic bilateral incision. No specific advantages of any type of the applied energy (i.e., mono-/bipolar HF current, cold incision, holmium/thulium YAG laser) could be documented...
June 23, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28646176/enhanced-atomic-desorption-of-209-and-210-francium-from-organic-coating
#18
Steinn Agustsson, Giovanni Bianchi, Roberto Calabrese, Lorenzo Corradi, Antonio Dainelli, Alen Khanbekyan, Carmela Marinelli, Emilio Mariotti, Luca Marmugi, Leonardo Ricci, Leonardo Stiaccini, Luca Tomassetti, Andrea Vanella
Controlled atomic desorption from organic Poly-DiMethylSiloxane coating is demonstrated for improving the loading efficiency of (209,210)Fr magneto-optical traps. A three times increase in the cold atoms population is obtained with contact-less pulsed light-induced desorption, applied to different isotopes, either bosonic or fermionic, of Francium. A six times increase of (210)Fr population is obtained with a desorption mechanism based on direct charge transfer from a triboelectric probe to the adatom-organic coating complex...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28643788/terahertz-saturable-absorbers-from-liquid-phase-exfoliation-of-graphite
#19
Vezio Bianchi, Tian Carey, Leonardo Viti, Lianhe Li, Edmund H Linfield, A Giles Davies, Alessandro Tredicucci, Duhee Yoon, Panagiotis G Karagiannidis, Lucia Lombardi, Flavia Tomarchio, Andrea C Ferrari, Felice Torrisi, Miriam S Vitiello
Saturable absorbers (SA) operating at terahertz (THz) frequencies can open new frontiers in the development of passively mode-locked THz micro-sources. Here we report the fabrication of THz SAs by transfer coating and inkjet printing single and few-layer graphene films prepared by liquid phase exfoliation of graphite. Open-aperture z-scan measurements with a 3.5 THz quantum cascade laser show a transparency modulation ∼80%, almost one order of magnitude larger than that reported to date at THz frequencies...
June 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/28640436/two-step-irradiance-schedule-versus-single-dose-cold-compress-for-pain-control-during-5-aminolevulinic-acid-based-photodynamic-therapy-of-condyloma-acuminatum
#20
Xiaonan Shao, Fang Wang, Bin Xu
OBJECTIVE: The purpose of this study was to investigate the effect of two-step irradiance schedule in relieving pain during PDT of CA. METHODS: The study was a prospective, controlled trial of 141 CA patients who were randomly divided into Group A (two-step irradiance schedule) and Group B (single-dose cold compress). The numeric rating scales (NRS) of patients' pain were recorded at 5, 10, 15, and 20 minutes during each PDT. RESULTS: The efficacy of PDT and NRS scores of patients in the two groups were compared...
June 22, 2017: Lasers in Surgery and Medicine
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