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https://www.readbyqxmd.com/read/29913715/repeated-sinomenine-administration-alleviates-chronic-neuropathic-pain-like-behaviours-in-rodents-without-producing-tolerance
#1
Tianle Gao, Tiansheng Shi, Dan-Qiao Wang, Zsuzsanna Wiesenfeld-Hallin, Xiao-Jun Xu
Background and aims We have previously reported that systemic administration of sinomenine produced antinociception in various experimental pain conditions in rodents, particularly in models of neuropathic pain. In the present study we assessed the effects of repeated administration of sinomenine in two rodent models of neuropathic pain in order to study the development of tolerance. Methods The analgesic effect of sinomenine was tested in female Sprague-Dawley rats that exhibited mechanical and cold hypersensitivity following ischaemic injury to the spinal cord and in male C57/BL6 mice that developed mechanical hypersensitivity after ischaemic injury to the sciatic nerve...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913679/assessment-of-small-fibers-using-evoked-potentials
#2
Caspar Skau Madsen, Nanna Brix Finnerup, Ulf Baumgärtner
Background and purpose Conventional neurophysiological techniques do not assess the function of nociceptive pathways and are inadequate to detect abnormalities in patients with small-fiber damage. This overview aims to give an update on the methods and techniques used to assess small fiber (Aδ- and C-fibers) function using evoked potentials in research and clinical settings. Methods Noxious radiant or contact heat allows the recording of heat-evoked brain potentials commonly referred to as laser evoked potentials (LEPs) and contact heat-evoked potentials (CHEPs)...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29911981/haptic-feedback-for-control-and-active-constraints-in-contactless-laser-surgery-concept-implementation-and-evaluation
#3
Emidio Olivieri, Giacinto Barresi, Darwin G Caldwell, Leonardo S Mattos
Haptics has proven to be highly beneficial in surgical robotics, bringing enhanced safety and precision by complementing the surgeon's visual channel. However, most of the research body in this context is dedicated to applications involving traditional "cold steel" surgical instruments. This paper proposes to bring the benefits of haptics to contactless surgeries, and presents a novel method to achieve this. The specific case of robot-assisted laser microsurgery is investigated. Here, a fictitious force feedback is created through stereoscopic visualization and 3D reconstruction, allowing the surgeon to sense the surgical area haptically while controlling a non-contact surgical laser...
April 2018: IEEE Transactions on Haptics
https://www.readbyqxmd.com/read/29889061/early-sign-of-microangiopathy-in-systemic-sclerosis-the-significance-of-cold-stress-test-in-dynamic-laser-doppler-flowmetry
#4
Sebastian Yu, Stephen Chu-Sung Hu, Hsin-Su Yu, Yi-Ying Chin, Yang-Chun Cheng, Chih-Hung Lee
BACKGROUND: Skin physiology measurement is receiving more attention for detecting vasculopathy in systemic sclerosis (SSc). Laser Doppler flowmetry (LDF) is a widely used physiological measurement to assess cutaneous microcirculation. However, findings of LDF may be normal during early stage of microangiopathy in SSc. OBJECTIVE: We hypothesized that cold stress test combined with LDF could detect early-stage microangiopathy in patients with SSc. METHODS: A 67-year-old male came with multiple ulcerations on his fingers for one year...
June 5, 2018: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29888724/antibiofilm-efficacies-of-cold-plasma-and-er-yag-laser-on-staphylococcus-aureus-biofilm-on-titanium-for-nonsurgical-treatment-of-peri-implantitis
#5
M Ulu, T Pekbagriyanik, F Ibis, S Enhos, U K Ercan
Objectives: The aim of the present study was to compare antibiofilm efficacies of the laser in contact and noncontact application modes and cold atmospheric plasma (CAP) on Staphylococcus aureus biofilm grown on sandblasted, large grit, acid-etched (SLA) titanium discs as an in vitro model of biofilm eradication on dental implant materials. Methods: S. aureus biofilm was matured on titanium discs for 7 days then, treated with contact and noncontact Er:YAG laser and CAP...
June 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29886468/-causes-and-management-for-male-urethral-stricture
#6
Caifang Chen, Mingqiang Zeng, Ruizhi Xue, Guilin Wang, Zhiyong Gao, Wuxiong Yuan, Zhengyan Tang
To explore the etiology of male urethral stricture, analyze the therapeutic strategies of urethral stricture, and summarize the complicated cases.
 Methods: The data of 183 patients with urethral stricture were retrospectively analyzed, including etiology, obstruction site, stricture length, therapeutic strategy, and related complications.
 Results: The mean age was 49.7 years, the average course was 64.7 months, and the constituent ratio of 51 to 65 years old patients was 38.8% (71/183). The traumatic injury of patients accounted for 52...
May 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29884103/effects-of-cervical-conisation-on-pregnancy-outcome-a-meta-analysis
#7
Hongmei Zhuang, Shurong Hong, Lin Zheng, Layue Zhang, Xueyi Zhuang, Hua Wei, Yuqing Yang
To assess the effect of cervical conisation on pregnancy outcome, a literature search strategy was conducted to identify all of the references lists of the relevant studies. The fixed or random effect model was used to calculate pooled RRs on the basis of heterogeneity. Twenty-seven publications with n cases and m controls were included in the meta-analysis. The results showed that conisation was associated with a higher risk of a preterm delivery (p = .010), PROM (p = .008), and a lower birth weight (p < ...
June 8, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29882538/identification-of-the-fragment-of-the-1-methylpyrene-cation-by-mid-ir-spectroscopy
#8
Pavol Jusko, Aude Simon, Gabi Wenzel, Sandra Brünken, Stephan Schlemmer, Christine Joblin
The fragment of the 1-methylpyrene cation, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:msub> <mml:mtext>C</mml:mtext> <mml:mrow> <mml:mn>17</mml:mn> </mml:mrow> </mml:msub> <mml:msubsup> <mml:mtext>H</mml:mtext> <mml:mrow> <mml:mn>11</mml:mn> </mml:mrow> <mml:mo>+</mml:mo> </mml:msubsup> <mml:mo>,</mml:mo> </mml:mrow> </mml:math> is expected to exist in two isomeric forms, 1-pyrenemethylium <mml:math xmlns:mml="http://www...
April 16, 2018: Chemical Physics Letters
https://www.readbyqxmd.com/read/29864797/note-a-3d-printed-alkali-metal-dispenser
#9
E B Norrgard, D S Barker, J A Fedchak, N Klimov, J Scherschligt, S Eckel
We demonstrate and characterize a source of Li atoms made from direct metal laser sintered titanium. The source's outgassing rate is measured to be 5(2) × 10-7 Pa L s-1 at a temperature T = 330 °C, which optimizes the number of atoms loaded into a magneto-optical trap. The source loads ≈107 7 Li atoms in the trap in ≈1 s. The loaded source weighs 700 mg and is suitable for a number of deployable sensors based on cold atoms.
May 2018: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29847633/functional-and-morphologic-alterations-in-mechanical-polymodal-and-cold-sensory-nerve-fibers-of-the-cornea-following-photorefractive-keratectomy
#10
Federico Bech, Omar González-González, Enol Artime, Joana Serrano, Ignacio Alcalde, Juana Gallar, Jesús Merayo-Lloves, Carlos Belmonte
Purpose: To define the characteristics and time course of the morphologic and functional changes experienced by corneal sensory nerves after photorefractive keratectomy (PRK). Methods: Unilateral corneal excimer laser photoablation was performed in 54 anesthetized 3- to 6-month-old mice; 11 naïve animals served as control. Mice were killed 0, 3, 7, 15, and 30 days after PRK. Excised eyes were placed in a recording chamber superfused at 34°C. Electrical nerve impulse activity of single sensory terminals was recorded with a micropipette applied onto the corneal surface...
May 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29802274/quantum-simulation-of-ultrafast-dynamics-using-trapped-ultracold-atoms
#11
Ruwan Senaratne, Shankari V Rajagopal, Toshihiko Shimasaki, Peter E Dotti, Kurt M Fujiwara, Kevin Singh, Zachary A Geiger, David M Weld
Ultrafast electronic dynamics are typically studied using pulsed lasers. Here we demonstrate a complementary experimental approach: quantum simulation of ultrafast dynamics using trapped ultracold atoms. Counter-intuitively, this technique emulates some of the fastest processes in atomic physics with some of the slowest, leading to a temporal magnification factor of up to 12 orders of magnitude. In these experiments, time-varying forces on neutral atoms in the ground state of a tunable optical trap emulate the electric fields of a pulsed laser acting on bound charged particles...
May 25, 2018: Nature Communications
https://www.readbyqxmd.com/read/29784962/carrier-thermometry-of-cold-ytterbium-atoms-in-an-optical-lattice-clock
#12
Chengyin Han, Min Zhou, Xiaohang Zhang, Qi Gao, Yilin Xu, Shangyan Li, Shuang Zhang, Xinye Xu
The ultracold atomic gas serving as the quantum reference is a key part of an optical lattice clock, and the temperature of atoms in the optical lattice affects the uncertainty and instability of the optical lattice clocks. Since the carrier spectrum of the clock transition in the lattices reflects the thermal dynamics of cold atoms, the temperature of atoms can be extracted from the carrier spectrum in a non-magic wavelength lattice of ytterbium optical clocks. Furthermore, the temperatures obtained from the carrier spectra are in good agreement with the results obtained by the time-of-flight method and thermometry based on the sideband spectrum...
May 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29758726/efficiency-at-maximum-power-of-a-laser-quantum-heat-engine-enhanced-by-noise-induced-coherence
#13
Konstantin E Dorfman, Dazhi Xu, Jianshu Cao
Quantum coherence has been demonstrated in various systems including organic solar cells and solid state devices. In this article, we report the lower and upper bounds for the performance of quantum heat engines determined by the efficiency at maximum power. Our prediction based on the canonical three-level Scovil and Schulz-Dubois maser model strongly depends on the ratio of system-bath couplings for the hot and cold baths and recovers the theoretical bounds established previously for the Carnot engine. Further, introducing a fourth level to the maser model can enhance the maximal power and its efficiency, thus demonstrating the importance of quantum coherence in the thermodynamics and operation of the heat engines beyond the classical limit...
April 2018: Physical Review. E
https://www.readbyqxmd.com/read/29758611/transition-from-wakefield-generation-to-soliton-formation
#14
Amol R Holkundkar, Gert Brodin
It is well known that when a short laser pulse propagates in an underdense plasma, it induces longitudinal plasma oscillations at the plasma frequency after the pulse, typically referred to as the wakefield. However, for plasma densities approaching the critical density, wakefield generation is suppressed, and instead the EM-pulse (electromagnetic pulse) undergoes nonlinear self-modulation. In this article we have studied the transition from the wakefield generation to formation of quasi-solitons as the plasma density is increased...
April 2018: Physical Review. E
https://www.readbyqxmd.com/read/29742720/sacral-epiduroscopic-laser-decompression-for-complex-regional-pain-syndrome-after-lumbar-spinal-surgery-a-case-report
#15
Jae-Wook Jung, Yong Han Kim, Hyojoong Kim, Eunsu Kang, Hyunji Jo, Myoung Jin Ko
RATIONALE: CRPS after a lumbar surgery has symptoms that are similar to PSSS. However, standard criteria for distinguishing CRPS from PSSS do not exist. We present a case report of a 31-year-old female with CRPS symptoms after lumbar spinal surgery treated by performing SELD. PATIENT CONCERNS: This patient was referred to our pain clinic for left ankle pain. She received a lumbar discectomy for a herniated lumbar disc (L5/S1) but the pain was aggravated after surgery...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29732217/comparison-of-cold-knife-optical-internal-urethrotomy-and-holmium-yag-laser-internal-urethrotomy-in-bulbar-urethral-strictures
#16
Mustafa Gurkan Yenice, Kamil Gokhan Seker, Emre Sam, Yunus Colakoglu, Feyzi Arda Atar, Selcuk Sahin, Abdulmuttalip Simsek, Volkan Tugcu
Introduction: To compare the results of cold-knife optical internal urethrotomy (OIU) and Holmium:YAG laser internal urethrotomy (HIU) in primary bulbar urethral strictures. Material and methods: A total of 63 patients diagnosed with primary bulbar urethral stricture between August 2014 and September 2015 were assigned to the OIU (n = 29) and HIU (n = 34) groups. The demographic variables, biochemistry panels, and preoperative and postoperative uroflowmetry results including the maximum flow rate (Qmax) and mean flow rate (Qmean) values, retrograde urethrography, and diagnostic flexible urethroscopy findings were recorded prospectively...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29716307/note-sensitive-fluorescence-detection-through-minimizing-the-scattering-light-by-anti-reflective-nanostructured-materials
#17
Supeng Xu, Yanning Yin, Ruoxi Gu, Meng Xia, Liang Xu, Li Chen, Yong Xia, Jianping Yin
We demonstrate a new approach with fabrication of anti-reflective coating to substantially reduce the scattering light in an ultra-high vacuum during laser induced fluorescence (LIF) detection. To do so, the surface of the vacuum chamber in the detection region was blackened and coated with the special solar heat absorbing nanomaterials. We demonstrate that more than 97.5% of the stray light in the chamber spanning from near infrared to ultraviolet can be absorbed which effectively improves the signal to noise (S/N) ratio...
April 2018: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29708730/development-of-a-high-resolution-laser-absorption-spectroscopy-method-with-application-to-the-determination-of-absolute-concentration-of-gaseous-elemental-mercury-in-air
#18
Abneesh Srivastava, Joseph T Hodges
Isotope dilution-cold-vapor-inductively coupled plasma mass spectrometry (ID-CV-ICPMS) has become the primary standard for measurement of gaseous elemental mercury (GEM) mass concentration. However, quantitative mass spectrometry is challenging for several reasons including (1) the need for isotopic spiking with a standard reference material, (2) the requirement for bias-free passive sampling protocols, (3) the need for stable mass spectrometry interface design, and (4) the time and cost involved for gas sampling, sample processing, and instrument calibration...
June 5, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29696252/stereochemistry-dependent-structure-of-hydrogen-bonded-protonated-dimers-the-case-of-1-amino-2-indanol
#19
Aude Bouchet, Johanna Klyne, Shun-Ichi Ishiuchi, Otto Dopfer, Masaaki Fujii, Anne Zehnacker
To understand the role of chirality in shaping biological supramolecular systems it is instructive to visualize the subtle effects of stereochemistry on the structure of model aggregates at the molecular level. Here, we apply conformer-specific IR-UV double-resonance laser spectroscopy in a cold ion trap to derive a detailed description of the protonated homodimers of (1R,2S)-cis- and (1R,2R)-trans-1-amino-2-indanol (c-AI2H+, t-AI2H+). Although the protonated monomers (c-AIH+, t-AIH+) only differ by the chirality of one carbon atom, their conformations are clearly distinct...
May 9, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29617447/increased-visceral-tissue-perfusion-with-heated-humidified-carbon-dioxide-insufflation-during-open-abdominal-surgery-in-a-rodent-model
#20
Jonathan P Robson, Pavlo Kokhanenko, Jean K Marshall, Anthony R Phillips, Jan van der Linden
Tissue perfusion during surgery is important in reducing surgical site infections and promoting healing. This study aimed to determine if insufflation of the open abdomen with heated, humidified (HH) carbon dioxide (CO2) increased visceral tissue perfusion and core body temperature during open abdominal surgery in a rodent model. Using two different rodent models of open abdominal surgery, visceral perfusion and core temperature were measured. Visceral perfusion was investigated using a repeated measures crossover experiment with rodents receiving the same sequence of two alternating treatments: exposure to ambient air (no insufflation) and insufflation with HH CO2...
2018: PloS One
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