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Electrophysiological monitoring

Hitomi Nakamura, Takayoshi Hosono, Keiichi Kumasawa, Carolyn J P Jones, John D Aplin, Tadashi Kimura
STUDY QUESTION: Can vaginal bioelectrical impedance (VZ) electrophysiologically determine alterations of the endometrium in preparation for implantation? SUMMARY ANSWER: VZ can electrophysiologically detect the sulfation and sialylation changes in the uterine glycocalyx in preparation for implantation. WHAT IS KNOWN ALREADY: Uterine receptivity is associated with various glycosylation changes that affect negative charge density at the luminal epithelial cell surface...
October 17, 2018: Human Reproduction
Zhimin Li, Jun Gao, Tianyu Wang, Yongning Li
To investigate effects of microvascular decompression (MVD) surgical treatment on hemifacial spasm.A retrospective analysis of 320 adult patients (95 male cases, 29.7% and 225 female cases, 70.3%) with hemifacial spasm treated by surgery was conducted between February 2007 to June 2016, with an average age of 49.3 years and average disease course of 4.9 years. All the 320 cases of patients received MVD. After surgery, all patients were followed up for an average of 2.3 years. Surgical effects were evaluated based on the patients' symptoms and signs...
October 2018: Medicine (Baltimore)
D Calvetti, J Prezioso, E Somersalo
Several key brain imaging modalities that are intended for retrieving information about neuronal activity in brain, the BOLD fMRI as a foremost example, rely on the assumption that elevated neuronal activity elicits spatiotemporally well localized increase of the oxygenated blood volume, which in turn can be monitored non-invasively. The details of the signaling in the neurovascular unit during hyperemia are still not completely understood, and remain a topic of active research, requiring good mathematical models that are able to couple the different aspects of the signaling event...
October 9, 2018: Journal of Theoretical Biology
Arne F Meyer, Jasper Poort, John O'Keefe, Maneesh Sahani, Jennifer F Linden
Breakthroughs in understanding the neural basis of natural behavior require neural recording and intervention to be paired with high-fidelity multimodal behavioral monitoring. An extensive genetic toolkit for neural circuit dissection, and well-developed neural recording technology, make the mouse a powerful model organism for systems neuroscience. However, most methods for high-bandwidth acquisition of behavioral data in mice rely upon fixed-position cameras and other off-animal devices, complicating the monitoring of animals freely engaged in natural behaviors...
October 10, 2018: Neuron
Pedro J Chacon, Limeng Pu, Tallis H da Costa, Young-Ho Shin, Taher Ghomian, Hamed Shamkhalichenar, Hsiao-Chun Wu, Brian A Irving, Jin-Woo Choi
Advances in several engineering fields have led to a trend towards miniaturization and portability of wearable biosensing devices, which used to be confined to large tools and clinical settings. Various systems to continuously measure electrophysiological activity through electrical and optical methods are one category of such devices. Being wearable and intended for prolonged use, the amount of noise introduced on sensors by movement remains a challenge and requires further optimization. User movement causes motion artifacts that alter the overall quality of the signals obtained, hence corrupting the resulting measurements...
October 9, 2018: IEEE Transactions on Bio-medical Engineering
Kaili Xu, Guohong Chen, Yanli Ma, Yuan Wang
BACKGROUND: To investigate the effect of early diagnosis in children with GreenBarre syndrome (GBS) via joint detection of biochemical markers and electrophysiological examination. METHODS: A total of 90 children with (GBS collected from the Department of Neurology, intensive care unit (ICU), Rehabilitation Department of Cerebral Palsy of Children's Hospital Affiliated to Zhengzhou University, Department of Pediatrics of First Affiliated Hospital of Zhengzhou University and Henan Province People's Hospital were selected as the research objects...
October 4, 2018: Minerva Pediatrica
William M Spees, Tsen-Hsuan Lin, Peng Sun, Chunyu Song, Ajit George, Sam E Gary, Hsin-Chieh Yang, Sheng-Kwei Song
Repetitive electrical activity produces microstructural alteration in myelinated axons, which may afford the opportunity to noninvasively monitor function of myelinated fibers in peripheral nervous system (PNS)/CNS pathways. Microstructural changes were assessed via two different magnetic-resonance-based approaches: diffusion fMRI and dynamic T2 spectroscopy in the ex vivo perfused bullfrog sciatic nerves. Using this robust, classical model as a platform for testing, we demonstrate that noninvasive diffusion fMRI, based on standard diffusion tensor imaging (DTI), can clearly localize the sites of axonal conduction blockage as might be encountered in neurotrauma or other lesion types...
October 8, 2018: Proceedings of the National Academy of Sciences of the United States of America
Che-Wei Wu, Gianlorenzo Dionigi, Marcin Barczynski, Feng-Yu Chiang, Henning Dralle, Rick Schneider, Zaid Al-Quaryshi, Peter Angelos, Katrin Brauckhoff, Jennifer A Brooks, Claudio R Cernea, John Chaplin, Amy Y Chen, Louise Davies, Gill R Diercks, Quan Yang Duh, Christopher Fundakowski, Peter E Goretzki, Nathan W Hales, Dana Hartl, Dipti Kamani, Emad Kandil, Natalia Kyriazidis, Whitney Liddy, Akira Miyauchi, Lisa Orloff, Jeff C Rastatter, Joseph Scharpf, Jonathan Serpell, Jennifer J Shin, Catherine F Sinclair, Brendan C Stack, Neil S Tolley, Sam Van Slycke, Samuel K Snyder, Mark L Urken, Erivelto Volpi, Ian Witterick, Richard J Wong, Gayle Woodson, Mark Zafereo, Gregory W Randolph
The purpose of this publication was to inform surgeons as to the modern state-of-the-art evidence-based guidelines for management of the recurrent laryngeal nerve invaded by malignancy through blending the domains of 1) surgical intraoperative information, 2) preoperative glottic function, and 3) intraoperative real-time electrophysiologic information. These guidelines generated by the International Neural Monitoring Study Group (INMSG) are envisioned to assist the clinical decision-making process involved in recurrent laryngeal nerve management during thyroid surgery by incorporating the important information domains of not only gross surgical findings but also intraoperative recurrent laryngeal nerve functional status and preoperative laryngoscopy findings...
October 6, 2018: Laryngoscope
Simone N Fueggle, Romola S Bucks, Allison M Fox
Sleep deprivation studies have highlighted the importance of adequate sleep for optimal daytime functioning. However, there is limited research exploring whether variations in natural sleep patterns produce similar difficulties to those seen in sleep deprivation studies. The aim of the current study was to explore whether naturalistic reductions in sleep duration and/or sleep quality were associated with behavioural and electrophysiological measures of cognitive control. Sixty undergraduate students were asked to wear an actigraph for 7 consecutive nights before completing a hybrid Flanker-Go/NoGo task whilst continuous EEG data were recorded...
October 2, 2018: International Journal of Psychophysiology
Rick Schneider, Gregory W Randolph, Gianlorenzo Dionigi, Che-Wei Wu, Marcin Barczynski, Feng-Yu Chiang, Zaid Al-Quaryshi, Peter Angelos, Katrin Brauckhoff, Claudio R Cernea, John Chaplin, Jonathan Cheetham, Louise Davies, Peter E Goretzki, Dana Hartl, Dipti Kamani, Emad Kandil, Natalia Kyriazidis, Whitney Liddy, Lisa Orloff, Joseph Scharpf, Jonathan Serpell, Jennifer J Shin, Catherine F Sinclair, Michael C Singer, Samuel K Snyder, Neil S Tolley, Sam Van Slycke, Erivelto Volpi, Ian Witterick, Richard J Wong, Gayle Woodson, Mark Zafereo, Henning Dralle
This publication offers modern, state-of-the-art International Neural Monitoring Study Group (INMSG) guidelines based on a detailed review of the recent monitoring literature. The guidelines outline evidence-based definitions of adverse electrophysiologic events, especially loss of signal, and their incorporation in surgical strategy. These recommendations are designed to reduce technique variations, enhance the quality of neural monitoring, and assist surgeons in the clinical decision-making process involved in surgical management of recurrent laryngeal nerve...
October 5, 2018: Laryngoscope
Nobutaka Masunaga, Yasuharu Matsunaga-Lee, Sen Matsumoto, Kouichi Tachibana, Yuzuru Takano
A 76-year-old man presented with frequent premature ventricular contractions (PVCs). The electrophysiological findings revealed the origin of the PVCs was in the posterior-superior process of the left ventricle (PSP-LV), which is anatomically adjacent to the infero-medial aspect of the right atrium (RA). After a failed ablation from the LV, ablation in the RA eliminated the PVCs. During additional ablation, the atrio-his (AH) interval was monitored by atrial overdrive pacing, and ablation was terminated immediately after the AH interval prolonged to 174 ms...
October 2018: Journal of Cardiology Cases
Vaclav Kremen, Benjamin Henry Brinkmann, Jamie J Van Gompel, Squire Matt M Stead, Erik K St Louis, Gregory A Worrell
OBJECTIVE: Automated behavioral state classification in intracranial EEG (iEEG) recordings may be beneficial for iEEG interpretation and quantifying sleep patterns to enable behavioral state dependent neuromodulation therapy in next generation implantable brain stimulation devices. Here, we introduce a fully automated unsupervised framework to differentiate between awake (AW), sleep (N2), and slow wave sleep (N3) using intracranial EEG (iEEG) only and validated with expert scored polysomnography...
October 2, 2018: Journal of Neural Engineering
George M Solomon, Inez Bronsveld, Kathryn Hayes, Michael Wilschanski, Paola Melotti, Steven M Rowe, Isabelle Sermet-Gaudelus
We describe a standardized measurement of nasal potential difference (NPD). In this technique, cystic fibrosis transmembrane conductance regulator (CFTR) and the epithelial sodium channel (ENaC) function are monitored by the change in voltage across the nasal epithelium after the superfusion of solutions that modify ion channel activity. This is enabled by the measurement of the potential difference between the subcutaneous compartment and the airway epithelium in the nostril, utilizing a catheter in contact with the inferior nasal turbinate...
September 13, 2018: Journal of Visualized Experiments: JoVE
Stephen Meisenhelter, Markus E Testorf, Mark A Gorenstein, Nicholas R Hasulak, Thomas K Tcheng, Joshua P Aronson, Barbara C Jobst
BACKGROUND: Electrocorticography studies are typically conducted in patients undergoing video EEG monitoring, but these studies are subject to confounds such as the effects of pain, recent anesthesia, analgesics, drug changes, antibiotics, and implant effects. NEW METHOD: Techniques were developed to obtain electrocorticographic (ECoG) data from freely moving subjects performing navigational tasks using the RNS® System (NeuroPace, Inc., Mountain View, CA), a brain-responsive neurostimulation medical device used to treat focal onset epilepsy, and to align data from the RNS System with cognitive task events with high precision...
September 26, 2018: Journal of Neuroscience Methods
Ning Yi, Zheng Cheng, Lei Yang, Gregory Edelman, Cuili Xue, Yi Ma, Hongli Zhu, Huanyu Cheng
Green electronics on biodegradable substrates from natural sources have gained broad interest due to the advantages of being biodegradable, recyclable, sustainable, and cost-efficient. This study presents a low-cost, yet simple extraction and purification method that explores aqueous extraction and precipitation with ethanol for the synthesis of galactomannan films. In salient contrast to the other materials of natural origin, the process to obtain galactomannan films is energy efficient and environmentally friendly...
September 28, 2018: ACS Applied Materials & Interfaces
Jessé Di Giacomo, Mariana Gongora, Farmy Silva, Renan Vicente, Oscar Arias-Carrion, Marco Orsini, Silmar Teixeira, Mauricio Cagy, Bruna Velasques, Pedro Ribeiro
Repetitive Transcranial Magnetic Stimulation (rTMS) studies are used to test motor imagery hypothesis. Motor Imagery (MI) represents conscious access to contents of movement intention, generally executed unconsciously during motor preparation. The main objective of this study was to investigate electrophysiological changes, which occurred before and after low-frequency rTMS application when we compared three different tasks: execution, action observation and motor imagery of finger movement. We hypothesize that absolute theta power over frontal regions would change between sensorimotor integration tasks and after 1 Hz of rTMS application...
September 22, 2018: Neuroscience Letters
Josef Sucec, Michaela Herzog, Ilse Van Diest, Omer Van den Bergh, Andreas von Leupoldt
Dyspnea (breathlessness) is a threatening and aversive bodily sensation and a major symptom of various diseases. It has been suggested to impair several aspects of functioning in affected patients, but experimental proof for this assumption is widely absent. Error processing is an important domain of functioning and has intensively been studied using electrophysiological measures. Specifically, the error-related negativity (ERN) has been suggested to reflect early performance monitoring and error detection, while the error positivity (Pe) has been linked to subsequent error awareness...
September 4, 2018: Psychophysiology
Amélie Calmont, Naomi Anderson, Jenifer P Suntharalingham, Richard Ang, Andrew Tinker, Peter J Scambler
Haploinsufficiency of the T-box transcription factor TBX1 is responsible for many features of 22q11.2 deletion syndrome. Tbx1 is expressed dynamically in the pharyngeal apparatus during mouse development and Tbx1 homozygous mutants display numerous severe defects including abnormal cranial ganglion formation and neural crest cell defects. These abnormalities prompted us to investigate whether parasympathetic (vagal) innervation of the heart was affected in Tbx1 mutant embryos. In this report, we used an allelic series of Tbx1 mouse mutants, embryo tissue explants and cardiac electrophysiology to characterise, in detail, the function of Tbx1 in vagal innervation of the heart...
September 23, 2018: Journal of Cardiovascular Development and Disease
Elena A Mermeklieva
AIMS: The aim of this study is to evaluate pattern visual evoked potentials as an objective electrophysiological method and to create reference values for Bulgarian population. METHODS AND MATERIALS: Standardized four-channel equipment 'Neuro-MEP 4' produced by 'Neurosoft' Company was used. A group of 47 healthy individuals (94 eyes) was studied. The stimulation was monocular, with a contrast-reversing pattern from black to white and vice versa. The investigation was performed with a three-channel recording with equipment adjustments according to the latest published ISCEV standard for pattern visual evoked potentials (2016)...
September 24, 2018: European Journal of Ophthalmology
Roy Amit, Dekel Abeles, Marisa Carrasco, Shlomit Yuval-Greenberg
The accurate extraction of signals out of noisy environments is a major challenge of the perceptual system. Forming temporal expectations and continuously matching them with perceptual input can facilitate this process. In humans, temporal expectations are typically assessed using behavioral measures, which provide only retrospective but no real-time estimates during target anticipation, or by using electrophysiological measures, which require extensive preprocessing and are difficult to interpret. Here we show a new correlate of temporal expectations based on oculomotor behavior...
September 14, 2018: NeuroImage
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