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Electrophysiological monitoring

Arina Prihestri Nugraheni, Irsad Andi Arso, Erika Maharani
Background: Idiopathic outflow tract ventricular premature contraction (VPC) can evolve into ventricular tachycardia (VT) via triggered activity mechanism. Transmural dispersion of repolarization (TDR) might play a role in idiopathic outflow tract VT by inducing phase 2 early afterdepolarization (EAD) and serve as the functional substrate for VT. Tp-Te/QT ratio as an arrhythmogenesis index has been reported to be associated with the incidence of ventricular arrhythmia. This study aims to investigate the association between Tp-Te/QT ratio with VT incidence in idiopathic outflow tract VPC...
August 2018: Cardiology Research
G A Tavartkiladze
The problems concerning the registration of late latency auditory responses to electric stimulation in the patients wearing cochlear implants are considered. The renewed interest to this class of evoked potentials is due to unexplained differences in the results of cochlear implantation in the patients with the similar audiological data, etiology, age and the history of deafness as well as cochlear implant surgery in children of first years of life and the extended possibilities for speech processor programming...
2018: Vestnik Otorinolaringologii
Robertino Dilena, Jacopo C DiFrancesco, Maria Virginia Soldovieri, Antonella Giacobbe, Paolo Ambrosino, Ilaria Mosca, Maria Albina Galli, Sophie Guez, Monica Fumagalli, Francesco Miceli, Dario Cattaneo, Francesca Darra, Elena Gennaro, Federico Zara, Pasquale Striano, Barbara Castellotti, Cinzia Gellera, Costanza Varesio, Pierangelo Veggiotti, Maurizio Taglialatela
Epilepsy of infancy with migrating focal seizures (EIMFS) is a rare early-onset developmental epileptic encephalopathy resistant to anti-epileptic drugs. The most common cause for EIMFS is a gain-of-function mutation in the KCNT1 potassium channel gene, and treatment with the KCNT1 blocker quinidine has been suggested as a rational approach for seizure control in EIMFS patients. However, variable results on the clinical efficacy of quinidine have been reported. In the present study, we provide a detailed description of the clinical, genetic, in vitro, and in vivo electrophysiological profile and pharmacological responses to quinidine of 2 EIMFS unrelated patients with a heterozygous de novo KCNT1 mutation: c...
August 15, 2018: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
Sebastian Schindler, Antonio Schettino, Gilles Pourtois
Processing affectively charged visual stimuli typically results in increased amplitude of specific event-related potential (ERP) components. Low-level features similarly modulate electrophysiological responses, with amplitude changes proportional to variations in stimulus size and contrast. However, it remains unclear whether emotion-related amplifications during visual word processing are necessarily intertwined with changes in specific low-level features or, instead, may act independently. In this pre-registered electrophysiological study, we varied font size and contrast of neutral and negative words while participants were monitoring their semantic content...
August 15, 2018: Scientific Reports
Katie Beadon, Raquel Guimarães-Costa, Jean-Marc Léger
PURPOSE OF REVIEW: Multifocal motor neuropathy (MMN) has specific clinical and electrophysiologic features but can be difficult to diagnose if cases are not typical. Intravenous immunoglobulin (IVIg) remains the core initial and long-term treatment. In this review, recent advances in the diagnosis, monitoring and treatment of MMN are discussed. RECENT FINDINGS: The pathology of MMN likely depends on immune-mediated attack of the nodes of Ranvier and paranodal regions leading to conduction block...
August 9, 2018: Current Opinion in Neurology
Hongbo Li, Xinwei Wei, Chenlei Gu, Kaiqi Su, Hao Wan, Ning Hu, Ping Wang
Okadaic acid (OA) and saxitoxin (STX) are typical toxins of diarrhetic shellfish poisoning (DSP) and paralytic shellfish poisoning (PSP), respectively, which are highly toxic marine toxins threatening human health and environmental safety. OA is a potent inhibitor of serine/threonine protein phosphatases that can cause cellular death, while STX is an inhibitor of sodium channel that can lead to neurological damage. In this work, a dual functional cardiomyocyte-based biosensor was proposed to detect DSP and PSP toxins by monitoring the viability and electrophysiology of cardiomyocytes...
2018: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
Daniel D Cavalcanti, Bárbara A Morais, Eberval G Figueiredo, Robert F Spetzler, Mark C Preul
BACKGROUND: Despite the latest development of microsurgery, electrophysiological monitoring and neuroimaging, the surgical management of intrinsic brainstem lesions remains a challenge. Several safe entry points have been described to access the different surfaces of the brainstem. The knowledge of this entry zones anatomy is critical to perform a safe and less morbid approach. To access the anterior midbrain surface a well-known entry point is the anterior mesencephalic (AM) zone. Our aim was to quantify the surgical AM zone exposure trough the orbitozygomatic (OZ) and subtemporal (ST) approaches...
August 7, 2018: World Neurosurgery
Brian J Lithgow, Zahra Moussavi, Caroline Gurvich, Jayashri Kulkarni, Jerome J Maller, Paul B Fitzgerald
Bipolar disorder (BD) is a severe mood disorder that lacks established electrophysiological, neuroimaging or biological markers to assist with both diagnosis and monitoring disease severity. This study's aim is to describe the potential of new neurophysiological features assistive in BD diagnosis and severity measurement utilizing the recording of electrical activity from the outer ear canal called Electrovestibulography (EVestG). From EVestG data sensory vestibulo-acoustic features were extracted from a single supine-vertical translation stimulus to distinguish 50 depressed and partly remitted/remitted bipolar disorder patients [18 symptomatic (BD-S, MADRS > 19), 32 reduced symptomatic (BD-R, MADRS ≤ 19)] and 31 age and gender matched healthy individuals (controls)...
August 6, 2018: European Archives of Psychiatry and Clinical Neuroscience
Yu-Jing Ding, Yu Song, Jun-Xiu Liu, Ya-Li Du, Li Zhu, Fu-Rong Ma
Background: Tinnitus is a common disorder that causes significant morbidity; however, the neurophysiological mechanism is not yet fully understood. A relationship between tinnitus and limbic system has been reported. As a significant component of the limbic system, the hippocampus plays an important role in various pathological processes, such as emotional disturbance, decreased learning ability, and deterioration of memory. This study was aimed to explore the role of the hippocampus in the generation of tinnitus by electrophysiological technology...
August 20, 2018: Chinese Medical Journal
Dennis Flachs, Tim Köhler, Christiane Thielemann
It is well known that at the interface between neuronal tissue and recording electrode low electrical impedance is required. However, if simultaneous optical detection or stimulation is an issue, good optical transmittance of the electrode material is desirable as well. State-of-the-art titanium nitride electrodes provide superior low impedance compared to gold or iridium, but are nontransparent. Transparent electrode materials like the transparent conducting oxide, indium tin oxide (ITO), or graphene offer high light transmittance (>80%) but reveal relatively high impedance...
August 6, 2018: Biointerphases
Yusuf Ehi, Hatice Kose Ozlece
Background: Nasal polyposis is a chronic disease presenting with nasal obstruction as the most frequent complaint. It has been documented that nasal polyposis results in deterioration of quality of life and disturbances of sleep. However, remarkable consequences of nasal polyposis such as psychological and cognitive outcomes are relatively poorly studied. Objective: The aim of the present study was to evaluate whether there is an impairment of concentration and attention in nasal polyposis patients due to hypoxia caused by nasal obstruction...
July 2018: Asia Pacific Allergy
Kevin R Cloonan, John Abraham, Sergio Angeli, Zainulabeuddin Syed, Cesar Rodriguez-Saona
Significant progress has been made in understanding the cues involved in the host and mate seeking behaviors of spotted wing drosophila, Drosophila suzukii (Matsumura). This insect pest has been discovered in many fruit growing regions around the world since 2008. Unlike closely related Drosophila species, D. suzukii attacks fresh fruit and has become a severe pest of soft fruits including strawberry, cherry, blackberry, blueberry, raspberry, and may pose a threat to grapes. Prior to 2008, little was known about the courtship and host-seeking behaviors or chemical ecology of this pest...
July 27, 2018: Journal of Chemical Ecology
Alexandra Kirsten, Stefan Linder, Sebastian Olbrich
Perspectives for the Electroencephalogram in Psychiatry Abstract. The electroencephalogram (EEG) is a non-invasive and cost-effective method to monitor spontaneous neuronal activity over time. Pathologies in EEG recordings indicate with high sensitivity but low specificity abnormal functional brain states. The main psychiatric indications for EEG recordings include atypical clinical symptoms of a neuropsychiatric syndrome or atypical reactions to medication as well as a baseline diagnostic before starting treatment with specific drugs or stimulation modalities...
July 2018: Praxis
Gunay Gurleyik, Mehmet Torun, Emin Gurleyik
Complication-free thyroid surgery is mainly based on the motor integrity of the recurrent laryngeal nerve (RLN). The nonrecurrent laryngeal nerve (non-RLN) is a rare anatomical variation that may increase the risk of vocal cord palsy. Early identification and exposure of the non-RLN may minimize injury risk. This case report presents functional detection of the non-RLN by intraoperative neuromonitoring (IONM). Total thyroidectomy was performed under the guidance of IONM on a patient with bulky multinodular goiter...
May 22, 2018: Curēus
Jennifer Kollmer, Markus Weiler, Jan Purrucker, Sabine Heiland, Stefan O Schönland, Ernst Hund, Christoph Kimmich, John M Hayes, Tim Hilgenfeld, Mirko Pham, Martin Bendszus, Ute Hegenbart
OBJECTIVE: To detect, localize, and quantify peripheral nerve lesions in amyloid light chain (AL) amyloidosis by magnetic resonance neurography (MRN) in correlation with clinical and electrophysiologic findings. METHODS: We prospectively examined 20 patients with AL-polyneuropathy (PNP) and 25 age- and sex-matched healthy volunteers. After detailed neurologic and electrophysiologic testing, the patient group was subdivided into mild and moderate PNP. MRN in a 3...
July 20, 2018: Neurology
Dandan Zhao, Xuelian Li, Haihai Liang, Nan Zheng, Zhenwei Pan, Yuhong Zhou, Xiao Liu, Ming Qian, Bozhi Xu, Ying Zhang, Ying Feng, Muge Qili, Qiuxia Wu, Baofeng Yang, Hongli Shan
BACKGROUND: Sorting nexin 17 (SNX17) is a critical cytoplasmic adaptor protein that regulates endosomal trafficking of membrane proteins to determine their recycling and/or degradation. The potential role of SNX17 in cardiovascular pathophysiology has not been reported. METHODS AND RESULTS: Cardiac arrhythmias were monitored using standard limb lead II electrocardiograph, and cardiac performances were determined by echocardiography in a rat model of myocardial infarction (MI) created by left anterior descending coronary artery ligation...
July 4, 2018: International Journal of Cardiology
Adnan I Qureshi, Nishath Naseem, Muhammad A Saleem, Shawn S Wallery, Faisal Raja
No abstract text is available yet for this article.
July 17, 2018: Journal of Neurosurgical Anesthesiology
Björn Bohman, Alyssa M Weinstein, C Rikard Unelius, Marcelo G Lorenzo
BACKGROUND: The triatomine bug Rhodnius prolixus Stål, 1859 (Heteroptera: Reduviidae) is the primary vector of Chagas disease in Colombia and Venezuela. An important step in controlling Chagas disease is monitoring the growth and spread of bug populations to inform effective management. Such monitoring could be carried out using pheromone traps. To develop effective pheromone traps, it is vital to understand the pheromone chemistry of R. prolixus. Previous studies have found that female R...
July 16, 2018: Parasites & Vectors
A Sebastian López-Chiriboga, Eoin P Flanagan
The field of autoimmune neurology is evolving rapidly. The discovery of autoantibodies that target neural antigens has expanded swiftly in the last decade. Recognition of the clinical syndromes associated with autoimmune neurologic disorders, and our understanding of the pathophysiology, has progressed significantly. Radiographic, electrophysiological, and laboratory testing (particularly neural autoantibody testing) are fundamental in the diagnosis of autoimmune neurological disorders and in the exclusion of mimics...
June 2018: Seminars in Neurology
Franziska Bender, Tatiana Korotkova, Alexey Ponomarenko
Extensive data on relationships of neural network oscillations to behavior and organization of neuronal discharge across brain regions call for new tools to selectively manipulate brain rhythms. Here we describe an approach combining projection-specific optogenetics with extracellular electrophysiology for high-fidelity control of hippocampal theta oscillations (5-10 Hz) in behaving mice. The specificity of the optogenetic entrainment is achieved by targeting channelrhodopsin-2 (ChR2) to the GABAergic population of medial septal cells, crucially involved in the generation of hippocampal theta oscillations, and a local synchronized activation of a subset of inhibitory septal afferents in the hippocampus...
June 29, 2018: Journal of Visualized Experiments: JoVE
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