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Electrophysiological monitoring

Magdalena Senderecka, Małgorzata Kossowska, Maciej Sekerdej, Jakub Szewczyk
The aim of the current study was to examine whether action monitoring is associated with religious fundamentalism. Participants performed a stop-signal task that required response inhibition to a simple auditory tone. The level of their religious fundamentalism was measured on a scale. Analysis with mixed-effects linear models revealed significantly larger error-related negativity, correct-related negativity, and post-error positivity components in individuals scoring higher on religious fundamentalism, pointing to their increased engagement in response monitoring...
December 12, 2018: Biological Psychology
Oluwaseun O Akinduro, Eric W Nottmeier
We describe the operative approach and management for thoracic metastatic disease in a 78-yr-old man with worsening mechanical lower back and left-sided thoracic radicular pain. Imaging of the thoracic spine revealed an osteolytic T11 mass with destruction of the left T11 pedicle and transverse process. Biopsy confirmed spinal metastasis from the liver. Preoperative angiogram was completed for localization of the artery of Adamkewicz and microparticle embolization of the left T11 intercostal artery. Surgical resection was supplemented with electrophysiological monitoring and neuronavigation...
December 14, 2018: Operative Neurosurgery (Hagerstown, Md.)
Vanessa A Jimenez, Xiaojie Wang, Natali Newman, Nicole A R Walter, Steven Gonzales, Jamie O Lo, Mathew M Ford, Verginia C Cuzon Carlson, Kathleen A Grant, Christopher D Kroenke
INTRODUCTION: Gestational ethanol exposure is associated with multiple developmental abnormalities, collectively termed fetal alcohol spectrum disorder (FASD). While the majority of women abstain from ethanol following knowledge of pregnancy, one contributing factor to the high FASD prevalence is that pregnancy is not detected until 4-6 weeks. Thus, ethanol consumption continues during the initial stages of fetal development. METHODS: An experimental protocol is described in which rhesus macaques self-administer 1...
December 14, 2018: Alcoholism, Clinical and Experimental Research
Xiao-Hong Zhu, Wei Chen
Brain relies on glucose and oxygen metabolisms to generate biochemical energy in the form of adenosine triphosphate (ATP) for supporting electrophysiological activities and neural signaling under resting or working state. Aging is associated with declined mitochondrial functionality and decreased cerebral energy metabolism, and thus, is a major risk factor in developing neurodegenerative diseases including Alzheimer's disease (AD). However, there is an unmet need in the development of novel neuroimaging tools and sensitive biomarkers for detecting abnormal energy metabolism and impaired mitochondrial function, especially in an early stage of the neurodegenerative diseases...
2018: Frontiers in Aging Neuroscience
Bahar Say, Ufuk Ergün, Ebru Turgal, İlknur Yardımcı
Clinical diagnosis of carpal tunnel syndrome (CTS) is confirmed by nerve conduction studies (NCS). In some cases, NCS may be normal. We aimed to demonstrate changes of distal motor latency (DML) and nerve conduction velocity (NCV) pathology of demyelination in entrapment neuropathy with cold application in case of clinical CTS with normal NCS. This prospective, cross-sectional, randomise, case-control involved 15 patients (25 hands) with clinically definite unilateral or bilateral CTS and normal nerve conduction studies (NCS), and 11 controls (22 hands)...
December 8, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Chris R Marcellino, Samuel Lapalme-Remis, Alejandro A Rabinstein, Jamie J Van Gompel, Gregory A Worrell, Eric T Payne, Sara Hocker
Seizures and other electrophysiological disturbances are an under-recognized cause of coma, focal deficits, and prolonged encephalopathy following subdural hematoma evacuation. In these patients, it is possible that seizures remain unrecognized on scalp EEG. It has been shown that a high burden of seizures and other electrophysiological disturbances exist following surgical evacuation and underlie the encephalopathy commonly seen in this patient population, predisposing them to medical complications and confounding estimates of prognosis...
December 10, 2018: Epileptic Disorders: International Epilepsy Journal with Videotape
Zhengjiang Liu, Zhiheng Zeng, Changdong Wu, Hua Liu
OBJECTIVE: The objective of the present investigation was to explore the possible effect of the 5-HT3 receptor antagonist tropisetron on the expression levels of the inflammatory factors interleukin 6 (IL-6), creatine kinase isoenzyme (CK-MB), soluble growth stimulating gene 2 protein (sST2) and immunoglobulin E (IgE), as well as the cardiac action potential in septic rats. METHODS: The cecal ligation and perforation (CLP) method was utilized to construct abdominal infarction in rats...
December 4, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Liron Boyman, George S B Williams, Andrew P Wescott, Jennie B Leach, Joseph P Y Kao, W Jonathan Lederer
Single-cell metabolic investigations are hampered by the absence of flexible tools to measure local partial pressure of O2 (pO2 ) at high spatial-temporal resolution. To this end, we developed an optical sensor capable of measuring local pericellular pO2 for subcellular resolution measurements with confocal imaging while simultaneously carrying out electrophysiological and/or chemo-mechanical single cell experiments. Here we present the OxySplot optrode, a ratiometric fluorescent O2 -micro-sensor created by adsorbing O2 -sensitive and O2 -insensitive fluorophores onto micro-particles of silica...
December 5, 2018: Journal of Molecular and Cellular Cardiology
Stefanos Archontakis, Konstantinos Sideris, Konstantina Aggeli, Konstantinos Gatzoulis, Michael Demosthenous, Panagiotis Tolios, Vasilios Lozos, Nikolas Koumallos, Dimitrios Limperiadis, Dimitrios Tousoulis, Ioannis Kallikazaros, Skevos Sideris
INTRODUCTION: Cardiac perforation of the right ventricle associated with pacemaker or implantable cardioverter-defibrillator (ICD) leads' implantation is an uncommon, albeit potentially life-threatening, complication. The aim of this study is to further identify the optimal therapeutic strategy especially when lead dislocation has occurred outside the pericardial sac. METHODS AND RESULTS: The study population included 10 consecutive patients (6 female, mean age: 66...
December 5, 2018: Journal of Cardiovascular Electrophysiology
Stephan Fleischer, Heinz-Georg Jahnke, Enrico Fritsche, Mathilde Girard, Andrea A Robitzki
Human pluripotent stem cell derived cardiomyocytes are a promising cell source for research and clinical applications like investigation of cardiomyopathies and therefore, identification and testing of novel therapeutics as well as for cell based therapy approaches. However, actually it´s a challenge to generate matured adult cardiomyocyte-like phenotype in a reasonable time. Moreover, there is a lack of applicable non-invasive label-free monitoring techniques providing quantitative parameters for analysing the culture stability and maturation status...
October 29, 2018: Biosensors & Bioelectronics
Noha Elsawy, Saly Elkholy, Radwa Azmy, Eman A Maher, Reham Shamloul
PURPOSE: Serious concerns about the effect of mobile phone radiation on cognition are growing. This study aimed to assess the possible effect of mobile phone radiation in persons with epilepsy and in normal subjects. METHODS: The amplitude and reaction time of auditory event-related potentials (P300) and occipital alpha frequency were compared before and after exposure with a 30-minute call in 30 persons with epilepsy and in 30 control subjects. Alpha power was monitored before, during, and after exposure to mobile phone radiation...
November 28, 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Jason E Chung, Hannah R Joo, Jiang Lan Fan, Daniel F Liu, Alex H Barnett, Supin Chen, Charlotte Geaghan-Breiner, Mattias P Karlsson, Magnus Karlsson, Kye Y Lee, Hexin Liang, Jeremy F Magland, Jeanine A Pebbles, Angela C Tooker, Leslie F Greengard, Vanessa M Tolosa, Loren M Frank
The brain is a massive neuronal network, organized into anatomically distributed sub-circuits, with functionally relevant activity occurring at timescales ranging from milliseconds to years. Current methods to monitor neural activity, however, lack the necessary conjunction of anatomical spatial coverage, temporal resolution, and long-term stability to measure this distributed activity. Here we introduce a large-scale, multi-site, extracellular recording platform that integrates polymer electrodes with a modular stacking headstage design supporting up to 1,024 recording channels in freely behaving rats...
November 17, 2018: Neuron
Kirill V Nourski, Mitchell Steinschneider, Ariane E Rhone, Christopher K Kovach, Hiroto Kawasaki, Matthew A Howard
Understanding cortical processing of spectrally degraded speech in normal-hearing subjects may provide insights into how sound information is processed by cochlear implant (CI) users. This study investigated electrocorticographic (ECoG) responses to noise-vocoded speech and related these responses to behavioral performance in a phonemic identification task. Subjects were neurosurgical patients undergoing chronic invasive monitoring for medically refractory epilepsy. Stimuli were utterances /aba/ and /ada/, spectrally degraded using a noise vocoder (1-4 bands)...
November 22, 2018: Hearing Research
Sophie A L Schacht, Patricia Stahn, Marius Hinsberger, Bernhard Schick, Gentiana I Wenzel
The tympanic membrane (TM) separates the outer ear from the tympanic cavity. Repeated pathologies can permanently decrease its tension, inducing conductive hearing loss and adhesive processes up to cholesteatoma. The current main therapy is its surgical reconstruction. Even though lasers have been proposed to tighten atrophic TMs, details of this effect, specifically histological analyses, are missing. We therefore used laser pulses to induce TM collagen remodeling in an animal model to compare the histological and electrophysiological effects of different applied laser intensities before entering clinical studies...
November 2018: Journal of Biomedical Optics
Tomas Robyns, Dieter Nuyens, Hua Rong Lu, David J Gallacher, Bert Vandenberk, Christophe Garweg, Joris Ector, Efstathios Pagourelias, Johan Van Cleemput, Stefan Janssens, Rik Willems
INTRODUCTION: Preventing sudden cardiac death (SCD) is one of the main goals in hypertrophic cardiomyopathy (HCM). Many variables have been proposed, however the European and American guidelines do not incorporate any ECG or Holter monitoring derived variables other than the presence of ventricular arrhythmia in their risk stratification models. In the present study we evaluated electrocardiographic parameters in risk stratification of HCM. METHODS AND RESULTS: Novel electrocardiographic parameters including the index of cardio-electrophysiological balance (iCEB), individualized QT correction (QTi) and QT rate dependence were evaluated along with established risk factors...
November 2018: Journal of Electrocardiology
(no author information available yet)
ObjectiveDisconnection of the cerebral hemispheres by corpus callosotomy (CC) is an established means to palliate refractory generalized epilepsy. Laser interstitial thermal therapy (LITT) is gaining acceptance as a minimally invasive approach to treating epilepsy, but this method has not been evaluated in clinical series using established methodologies to assess connectivity. The goal in this study was to demonstrate the safety and feasibility of MRI-guided LITT for CC and to assess disconnection by using electrophysiology- and imaging-based methods...
November 1, 2018: Journal of Neurosurgery
Christian Valt, Dorothea Huber, Ingrid Erhardt, Birgit Stürmer
Self-absorption describes a pathological tendency towards the internal mental world (internalization) that often conflicts with the accurate monitoring of the external world. In performance monitoring, an augmented electrophysiological response evoked by internal signals in patients with anxiety or depressive disorder seems to reflect this tendency. Specifically, the error-related negativity (Ne/ERN), an index of error processing based on internal signals, is larger in patients compared to controls. In the present experiment, we investigated whether the preferential processing of internal signals in patients is linked to diminished and inflexible external signal processing...
2018: PloS One
Sean C Beinart, Andrea Natale, Atul Verma, Alpesh Amin, Scott Kasner, Hans-Cristoph Diener, Maurizio Del Greco, Bruce L Wilkoff, Erika Pouliot, Noreli Franco, Suneet Mittal
BACKGROUND: Traditionally, insertable cardiac monitor (ICM) procedures have been performed in the cardiac catheterization (CATH) or electrophysiology (EP) laboratory. The introduction of the miniaturized Reveal LINQ ICM has led to simplified and less invasive procedures, affording hospitals flexibility in planning where these procedures occur without compromising patient safety or outcomes. METHODS: The present analysis of the ongoing, prospective, observational, multicenter Reveal LINQ Registry sought to provide real-world feasibility and safety data regarding the ICM procedure performed in the CATH/EP lab or operating room and to compare it with insertions performed outside of these traditional hospital settings...
October 14, 2018: American Heart Journal
Hui-Chen Han, Francis J Ha, Andrew W Teh, Paul Calafiore, Elizabeth F Jones, Jennifer Johns, Anoop N Koshy, David O'Donnell, David L Hare, Omar Farouque, Han S Lim
Background The relationship between mitral valve prolapse ( MVP ) and sudden cardiac death ( SCD ) remains controversial. In this systematic review, we evaluate the relationship between isolated MVP and SCD to better define a potential high-risk subtype. In addition, we determine whether premortem parameters could predict SCD in patients with MVP and the incidence of SCD in MVP . Methods and Results Electronic searches were conducted in PubMed and Embase for all English literature articles published between 1960 and 2018 regarding MVP and SCD or cardiac arrest...
December 4, 2018: Journal of the American Heart Association
Elif Isbell, Susan D Calkins, Veronica T Cole, Margaret M Swingler, Esther M Leerkes
Identifying the links between specific cognitive functions and emergent academic skills can help determine pathways to support both early academic performance and later academic achievement. Here, we investigated the longitudinal associations between a key aspect of cognitive control, conflict monitoring, and emergent academic skills from preschool through first grade, in a large sample of socioeconomically diverse children (N = 261). We recorded event-related potentials (ERPs) during a Go/No-Go task. The neural index of conflict monitoring, ΔN2, was defined as larger N2 mean amplitudes for No-Go versus Go trials...
November 26, 2018: Developmental Psychobiology
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