Johan Gyllensvärd, Marie Studahl, Lars Gustavsson, Elisabet Hentz, Karin Åkesson, Huiqi Li, Mikael Norman, Anders Elfvin
IMPORTANCE: Antibiotic treatment saves lives in newborns with early-onset sepsis (EOS), but unwarranted antibiotic use is associated with resistant bacteria and adverse outcomes later in life. Surveillance is needed to optimize treatment strategies. OBJECTIVE: To describe antibiotic use in association with the incidence and mortality from EOS among late-preterm and full-term newborns. DESIGN, SETTING, AND PARTICIPANTS: The Sweden Neonatal Antibiotic Use study was a nationwide observational study that included all late-preterm and full-term neonates born from January 1, 2012, to December 31, 2020, in neonatal units of all levels...
March 4, 2024: JAMA Network Open