Ying Huang, Chenjie Xu, Tao Zeng, Zhongming Li, Yanzhi Xia, Gaojian Tao, Tong Zhu, Lijuan Lu, Jing Li, Taiyuan Huang, Hongbo Huai, Benxiang Ning, Chao Ma, Xinxing Wang, Yuhua Chang, Peng Mao, Jian Lin
BACKGROUND: Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The treatment of PHN remains a challenge for clinical pain management. Despite the effectiveness of anticonvulsants, antidepressants, and lidocaine patches in reducing PHN, many patients still face intractable pain disorders. In this randomized controlled study, we evaluated whether hydromorphone through intravenous patient-controlled analgesia (IV PCA) was effective in relieving PHN. METHODS: Patients with PHN were randomly divided into two groups, one group received oral pregabalin with IV normal saline, another group received oral pregabalin with additional IV PCA hydromorphone for two weeks...
April 1, 2021: Korean Journal of Pain