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Hydrocephalus treatment

Cecilia L Dalle Ore, Peter Abraham, Luke P Burns, Samuel Lance, Amanda Gosman, Hal S Meltzer
Reconstructive cranioplasty can be associated with many complications and add to the not insignificant potential risks associated with decompressive craniectomy. In the setting of post-traumatic hydrocephalus, treatment with a ventriculoperitoneal (VP) shunt prior to reconstructive cranioplasty likely increases these risks even further. The authors report a case of a 17-year-old male with a history of a severe closed head injury who initially suffered a life-threatening complication associated with intracranial hypotension after cranioplasty only to succumb to malignant intracranial hypertension following a second cranioplasty attempt...
June 20, 2018: Journal of Craniofacial Surgery
Ya A Latyshev, A D Kravchuk, L B Likhterman, N E Zakharova, O S Zaytsev, A G Gavrilov, V A Okhlopkov, A A Potapov
One of the frequent consequences of severe traumatic brain injury is posttraumatic hydrocephalus that not only hampers the processes of consciousness recovery, rehabilitation, and social adaptation of patients but also is the cause of disability. Pathological processes underlying the clinical picture of posttraumatic hydrocephalus and the relationship between CSF circulation disorders and structural changes in the brain substance have not been adequately studied. Of particular importance are patients in the chronic vegetative or minimally conscious state, recovery from which is blocked by posttraumatic hydrocephalus...
2018: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
Desmond P Kidd
OBJECTIVE: Neurological complications of systemic sarcoidosis are uncommon and the natural history and optimal treatments under-researched. With the advent of modern biological therapies, it is important to define the clinical characteristics and immunopathology of the disease. METHODS: Patients referred to and treated within the Centre for Neurosarcoidosis over a 15 year period who had biopsy-proven "highly probable" disease of the central nervous system were studied prospectively...
June 19, 2018: Journal of Neurology
Giorgio Palandri, Thomas Sorenson, Mino Zucchelli, Nicola Acciarri, Paolo Mantovani, Carmelo Sturiale
Cavernous malformations of the third ventricle are uncommon vascular lesions. Evidence suggests that cavernous malformations in this location might have a more aggressive natural history due to their risk of intraventricular hemorrhage and hydrocephalus.1 The gold standard of treatment is considered to be microsurgical gross total resection of the lesion. However, with progressive improvement in endoscopic capabilities, several authors have recently advocated for the role of minimally-invasive neuroendoscopy for resecting intraventricular cavernous malformations...
June 16, 2018: Operative Neurosurgery (Hagerstown, Md.)
A S Kamat, A Gretschel, A J Vlok, R Solomons
INTRODUCTION: Hydrocephalus occurs in 85% of patients with tuberculous meningitis (TBM). Ventriculoperitoneal shunt (VPS) insertion is first-line treatment for relieving increased intercranial pressure. VPS obstruction secondary to increased protein levels in cerebrospinal fluid (CSF) is a known complication. OBJECTIVE: To ascertain if there is a difference in protein levels 1) between cranial and lumbar CSF, and to quantify levels associated with VPS obstruction, and 2) obtained from lumbar puncture vs...
July 1, 2018: International Journal of Tuberculosis and Lung Disease
Mónica Ramírez, Eduardo Cortés, José Betancur, Carlos Garcés
Cerebral tuberculosis TB (tuberculomas) without meningitis is an uncommon disease with a high morbidity and mortality. We report on a case that illustrates the complexity of this clinical presentation. An 11 month old, previously healthy male infant was brought to the clinic due to fever present during the last 1.5 months, associated with loss of neurodevelopmental goals and signs of endocranial hypertension. CT scan of the skull revealed dilatation of the ventricular system with transependimary edema; MRI showed multiple intra- and extra-axial micronodular images and hydrocephalus...
April 2018: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
Markus Bookland, Min Tang-Schomer, Eileen Gillan, Antonina Kolmakova
BACKGROUND: Juvenile pilocytic astrocytomas represent the largest group of pediatric brain tumors. The ideal management for these tumors is early, total surgical resection. To detect and track treatment response, a screening tool is needed to identify patients for surgical evaluation and assess the quality of treatment. The identification of aberrant miRNA profiles in the sera of juvenile pilocytic astrocytoma patients could provide such a screening tool. METHODS: The authors reviewed the serum profiles of 84 oncologically relevant miRNAs in pediatric juvenile pilocytic astrocytoma patients via qPCR screening...
June 18, 2018: Acta Neurochirurgica
Harminder Singh, M Burhan Janjua, Mudassir Ahmed, Yoshua Esquenazi, Sivashanmugam Dhandapani, Elizabeth Mauer, Theodore H Schwartz, Mark S Souweidane
Colloid cysts have been associated with acute neurologic deterioration and sudden death. However, the low incidence of associated sudden deaths has meant that factors influencing outcome in patients who present with acute neurological deterioration have not been extensively published. A PubMed literature search was performed to identify reported patients who presented with acute neurological deterioration with radiographic or histopathologic diagnosis of a colloid cyst. Demographic data, presenting symptoms, physical exam, surgical interventions, and outcomes were recorded...
June 12, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Tong Sun, Yikai Yuan, Qiuming Zhang, Yicheng Zhou, Xuepei Li, Hang Yu, Meng Tian, Junwen Guan
OBJECTIVE: Lumboperitoneal shunt (LPS) has been demonstrated an effective method for the treatment of communicating hydrocephalus in the presence of frequent shunt failure. To determine if establishing a preoperative evaluation system could benefit patients thus attenuating the risk of LPS failure. METHODS: In this three-year study, treated by LPS, patients undergoing preoperative evaluation were included into study group and others without preoperative evaluation were included into control group...
June 12, 2018: World Neurosurgery
Mohammed Aloddadi, Safar Alshahrani, Ibrahim Alnaami
The management of hydrocephalus represents a neurosurgical challenge. Ventriculoperitoneal (VP) shunts are usually the treatment of choice for hydrocephalus. However, when VP shunt is not an option, ventriculoatrial (VA) shunt becomes a second choice. VA shunts have special complications such as postoperative neck hematomas, shunt nephritis, and migration of the distal segment. There are two main techniques for the retrieval of migrated VA shunt: either by retrieval of the broken segment by thoracotomy, which is highly invasive, or by transvenous approach...
January 2018: Journal of Pediatric Neurosciences
Ibrahim Alatas, Gokhan Canaz, Gulseren Arslan, Serdar Cevik, Belgu Kacmaz, Nursu Kara, Huseyin Canaz
Context: Spina bifida, hydrocephalus, and similar congenital central nervous system (CNS) anomalies take origin from embryologic stages weeks before birth, but assessment and follow-up of these patients are important to figure and predict the effects of these anomalies on child's neurodevelopment. Aims: To evaluate of multiple groups of congenital CNS anomalies in the neurodevelopment level. Settings and Design: The study was conducted at a research and treatment center for spina bifida patients...
January 2018: Journal of Pediatric Neurosciences
Banshi Lal Kumawat, Chandra Mohan Sharma, Pankaj Kumar Saini, Ankur Garg
Chronic Myeloid Leukaemia (CML) presenting with isolated Central Nervous System (CNS) blast crisis is an uncommon entity. A 22-year-old man, diagnosed with chronic phase CML in 2011 and was in haematological and cytogenetic remission until July 2016, had acute onset headache and vomiting with meningeal signs and was admitted elsewhere, investigated by brain imaging and cerebrospinal fluid (CSF) analysis and suspected to have tubercular meningitis, for which steroids and antitubercular medications were started...
June 12, 2018: BMJ Case Reports
Charuta Furey, Prince Antwi, Daniel Duran, Andrew T Timberlake, Carol Nelson-Williams, Charles C Matouk, Michael L DiLuna, Murat Guenel, Kristopher T Kahle
Hydrocephalus, a disorder of impaired cerebrospinal fluid (CSF) homeostasis, often results from an imbalance between CSF production and reabsorption. Rarely, hydrocephalus is the consequence of CSF hypersecretion in the context of diffuse villous hyperplasia of the choroid plexus (DVHCP). The limited genetic information in previously reported cases suggests a high prevalence of gains of chromosome 9p in this disease, although the critical genes involved in DVHCP pathogenesis have not been identified. Here, we report a patient with syndromic hydrocephalus with DVHCP associated with a novel 9p24...
June 12, 2018: Cold Spring Harbor Molecular Case Studies
(no author information available yet)
Objective: To analyze the epidemiological characteristics (pathogenic bacteria distribution, clinical menifestations and outcomes) of neonatal bacterial meningitis in parts of Guangdong Province and Guangxi Zhuang Autonomous Region. Methods: A retrospective epidemiological study was carried out in the infants with bacterial meningitis admitted to 12 hospitals in Guangdong Province and Guangxi Zhuang Autonomous Region from January 2011 to December 2016. The distribution of pathogenic bacteria and epidemiological characteristics were analyzed during different periods (2011-2012, 2013-2014, 2015-2016), between early-onset and late-onset cases, preterm infants and term infants...
June 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
Hamid-Borghei Razavi, Hilary Koech, Mayur Sharma, Daria Krivosheya, Bryan S Lee, Gene Barnett, Alireza Mohammadi
OBJECTIVE: The application of laser interstitial thermal therapy (LITT) for intracranial lesions in the posterior fossa tumors remains challenging due to the smaller size of this compartment as well as the thickness and angle of the occipital bone. The objective of this study was to review our experience with this treatment modality for posterior fossa lesions. METHODS: We retrospectively reviewed our series of eight patients with posterior fossa tumors treated with LITT from an IRB approved brain tumor database (2012 to 2017) of over 200 LITT cases in our institution...
June 5, 2018: World Neurosurgery
Theresa Krätzig, Marc Dreimann, Klaus Christian Mende, Ingo Königs, Manfred Westphal, Sven Oliver Eicker
BACKGROUND: Spinal adhesive arachnoiditis (SAA) is an inflammatory process of the meninges. Cystic changes and cicatrisation may lead to neurological deficits and immobilization. Therapy is difficult and often unsatisfactory. We describe eight cases of extensive SAA following extradural spinal infection. METHODS: 238 patients with epidural abscess or osteomyelitis were treated at our institution between 2011 and 2018. We identified eight patients who developed extensive SAA on follow-up...
June 5, 2018: World Neurosurgery
Наталия И Гасюк, Наталия С Артемова, Елена М Ковалева, Валерий И Похилько, Галина А Соловьева
OBJECTIVE: Introduction: Intraventricular hemorrhage (IVH) causes increased morbidity and mortality in premature infants and is associated with adverse neurological outcomes. The aim of the research is to confirm the role of genes of renin-angiotensin system in the development of adverse outcomes of treatment of severe IVC in preterm. PATIENTS AND METHODS: Materials and methods: A prospective study was conducted, which included 58 premature infants (average birth weight 1016...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Mark Scaife, Ryan Abegglen, Christina Vila, Kurt Stahlfeld
Ventriculo-peritoneal, -gallbladder, -pleural, -atrial, and -jugular shunts are all viable options in the treatment of hydrocephalus 1, 2, 3. Retrieval of these catheters can often be very difficult and may be unsuccessful or incomplete. Retained catheters can result in unforeseen and unexpected complications.
June 2018: Clinical Case Reports
Sascha Marx, Joerg Baldauf, Marc Matthes, Michael R Gaab, Henry W S Schroeder
BACKGROUND: During the 1990s, endoscopic aqueductoplasty (AP) was considered to be a valuable alternative to endoscopic third ventriculostomy (ETV) in treating hydrocephalus related to idiopathic aqueductal stenosis (iAS), with promising short-term outcomes. OBJECTIVE: To evaluate the long-term outcome of AP in the treatment of iAS. METHODS: Long-term follow-up clinical examinations and magnetic resonance (MR) imaging were performed for patients treated by an AP for iAS in our department...
June 7, 2018: Neurosurgery
Michael S Golinko, John D Pemberton, James Phillips, Adam Johnson, Larry D Hartzell
Tessier No 3 facial cleft (oro-nasal-ocular clefts) is the rarest and most challenging of all the Tessier clefts. Reports on Tessier No 3 clinical findings, surgical techniques, and outcomes are varied due to the scarcity of patients and the wide range of phenotypic findings. The authors present our experience of 2 children born with Tessier No 3 clefts who were both managed at the Arkansas Children's Hospital. Our purpose is to add knowledge on this rare craniofacial cleft by providing detailed soft tissue findings, skeletal findings, operative techniques, early postoperative outcome, and suggestions of a treatment protocol...
June 5, 2018: Journal of Craniofacial Surgery
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