keyword
https://read.qxmd.com/read/38496113/pediatric-cerebral-venous-sinus-thrombosis-a-case-report
#1
Pruthvi Patel, Shirley M Gandhi, Philip P Breton, Tetiana Litvinchuk
Cerebral venous sinus thrombosis (CVST) in infants is a rare vascular disorder that presents with nonspecific symptoms leading to a delay in diagnosis and treatment. Thrombus formation in the cerebral sinuses prevents blood from draining out of the brain leading to local and systemic complications. Here, we present an 11-week-old patient who presented to the emergency department (ED) with three days of lethargy, multiple episodes of projectile emesis, increased fussiness, and downward gaze. A CT scan demonstrated intraventricular hemorrhage (IVH) with acute hydrocephalus...
February 2024: Curēus
https://read.qxmd.com/read/38493773/arginine-vasopressin-deficiency-in-children-with-craniopharyngioma-and-cerebral-germ-cell-tumour-two-sides-of-the-same-coin-clinical-and-radiological-features
#2
JOURNAL ARTICLE
Sabrina Criscuolo, Cristina Partenope, Mario Tortora, Ved Bhushan Arya, Assunta Albanese
INTRODUCTION: Paediatric brain tumours in the sellar-suprasellar region (SSR) are often associated with arginine vasopressin peptide deficiency (AVPD), either at diagnosis caused by the tumour itself or during follow-up as consequence of treatments. The purpose of this research is to retrospectively describe the neuroradiological characteristics and the timing of AVPD development in a cohort of paediatric patients with craniopharyngioma (CP) or germ cell tumours (GCT). METHODS: We evaluated brain MRI at tumour diagnosis and at the onset of AVPD, as well as recorded clinical, endocrinological and histopathological data, treatments, and outcome...
March 15, 2024: Hormone Research in Pædiatrics
https://read.qxmd.com/read/38492280/the-most-common-congenital-malformations-in-dogs-literature-review-and-practical-guide
#3
REVIEW
Marina Vilela Estevam, Gilson Helio Toniollo, Maricy Apparicio
Congenital malformations can affect almost 7% of canine newborns. The increase of commercial dog breeding and inbreeding used to maintain the striking characteristics of each breed, the appearance of malformations has become increasingly common, especially in brachycephalic dogs. The causes are diverse, and include genetic, nutritional, iatrogenic, and infectious factors, often making it difficult to establish a cause-consequence relationship. The high mortality associated with malformations comes not only from the fact that some are incompatible with life, but also because even if many undergo surgical treatment or correction, they require specific management, monitoring, and clinical treatment for an indefinite period of time...
March 13, 2024: Research in Veterinary Science
https://read.qxmd.com/read/38486744/intraventricular-dimethyl-sulfoxide-dmso-induces-hydrocephalus-in-a-dose-dependent-pattern
#4
JOURNAL ARTICLE
Leandro Castaneyra-Ruiz, Jenna Ledbetter, Seunghyun Lee, Anthony Rangel, Evelyn Torres, Bianca Romero, Michael Muhonen
INTRODUCTION: Dimethyl sulfoxide (DMSO), a widely utilized solvent in the medical industry, has been associated with various adverse effects, even at low concentrations, including damage to mitochondrial integrity, altered membrane potentials, caspase activation, and apoptosis. Notably, therapeutic molecules for central nervous system treatments, such as embolic agents or some chemotherapy drugs that are dissolved in DMSO, have been associated with hydrocephalus as a secondary complication...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38485323/recurrent-disseminated-coccidioidal-meningitis-in-two-subsequent-pregnancies
#5
Jonathan E Blohm, Lee R McMahon, Chaur-Dong Hsu
OBJECTIVE: Recurrent disseminated coccidioidal meningitis in two subsequent pregnancies is rare and can pose a challenge in ensuring the health of both mother and baby. In this unique case we highlight this rare occurrence and subsequent treatment. CASE REPORT: A 29-year-old G4P1021 with a history of disseminated coccidioidomycosis in a previous pregnancy presented at 8 weeks gestation with nausea, headache, and neck pain. Cerebrospinal fluid analysis was positive for recurrent coccidioidal infection...
March 2024: Taiwanese Journal of Obstetrics & Gynecology
https://read.qxmd.com/read/38485197/prognostic-significance-of-central-skull-base-remodeling-in-chiari-ii-malformation
#6
JOURNAL ARTICLE
John T Freiling, Nilesh K Desai, Stephen F Kralik, William E Whitehead, Thierry A G M Huisman
BACKGROUND AND PURPOSE: Outward convexity of the basiocciput and posterior atlanto-occipital membrane are common in patients with Chiari II malformation associated with an open neural tube defect. We aimed to determine if the severity of these findings correlated with the need for future hydrocephalus treatment. MATERIALS AND METHODS: A retrospective chart and imaging review identified patients who underwent open neural tube defect repair at a quaternary care pediatric hospital from July 2014 through September 2022...
March 14, 2024: AJNR. American Journal of Neuroradiology
https://read.qxmd.com/read/38476219/can-diffuse-reflectance-spectroscopy-identify-shuntodynia-in-pediatric-hydrocephalus-patients
#7
JOURNAL ARTICLE
Olivia Kline, Karthik Vishwanath, Boyd Colbrunn, Andrew Peachman, Jing Zhang, Sudhakar Vadivelu
SIGNIFICANCE: Shuntodynia is patient reported pain at the site of the implanted ventriculoperitoneal (VP) shunt. Pediatric hydrocephalus requiring shunt placement is a chronic and prevalent standard of care treatment and requires lifetime management. Shuntodynia is a subjective measure of shunt dysfunction. Quantitative, white-light tissue spectroscopy could be used to objectively identify this condition in the clinic. AIM: Pediatric subjects were recruited for optical sensing during routine clinical follow-up visits, post-VP shunt implantations...
March 2024: Journal of Biomedical Optics
https://read.qxmd.com/read/38468682/stereotactic-placement-of-dual-lumen-catheter-system-for-continuous-drainage-irrigation-and-intraventricular-antibiotic-therapy-for-treatment-of-brain-abscess-with-ventriculitis-a-case-report-and-literature-review
#8
Domenico Policicchio, Lucio Cosco, Giuseppe Mauro, Alfonso Nicola Iannello, Luigi Santaguida, Virginia Vescio, Giosué Dipellegrini
BACKGROUND: Cerebral abscesses complicated by ventriculitis present significant treatment challenges, often associated with high morbidity and mortality. Traditional management approaches, including systemic antibiotic therapy and external ventricular drainage (EVD), face limitations due to the blood-brain barrier and risks of catheter-related complications. This report discusses a case where the dual-lumen catheter system, an innovative neurosurgical tool integrating continuous irrigation with drainage, was employed...
2024: Surgical Neurology International
https://read.qxmd.com/read/38468651/single-institution-series-describing-external-ventricular-drain-evd-placement-and-short-and-long-term-complications-related-to-placement-accuracy
#9
JOURNAL ARTICLE
Nikhil Sharma, Jeffery R Head, Arka N Mallela, Regan M Shanahan, Stephen P Canton, Hussam Abou-Al-Shaar, Nicolás Matheo Kass, Fritz Steuer, Lucille Cheng, Michael Raver, Edward G Andrews
BACKGROUND: The placement of an external ventricular drain (EVD) for the treatment of acute hydrocephalus is one of the most common life-saving procedures that neurosurgeons perform worldwide. There are many well-known complications associated with EVD placement, including tract hemorrhages, intra-parenchymal and subdural hemorrhages, infection, and catheter misplacement. Given the variety of complications associated with EVD placement and the inconsistent findings on the relationship of accuracy to complications, the present study reviewed short- and long-term complications related to EVD placement at our institution...
2024: Surgical Neurology International
https://read.qxmd.com/read/38465824/-possibilities-of-dynamic-phase-contrast-mri-of-cerebrospinal-fluid-for-performing-a-tap-test-in-a-patient-with-idiopathic-normotensive-hydrocephalus
#10
JOURNAL ARTICLE
D V Nikitin, M B Dolgushin, A V Dvoryanchikov, T M Rostovtseva, I V Senko, R T Tairova
Idiopathic normotensive hydrocephalus (iNH) is a widespread disease in elderly patients. The effectiveness of iNG treatment and the subsequent quality of patients' lives directly depends on timely and early diagnosis. The criteria for diagnosing iNG that are used in neuroimaging can also be found in patients without clinical manifestations of this disease, and the widely used tap-test is an invasive technique with a rather low sensitivity. The need for early diagnosis and initiation of treatment before the development of irreversible damage to brain structures determines the relevance of the search for an accessible, minimally invasive, accurate and safe diagnostic method...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38465024/endocrinopathies-in-a-pediatric-patient-post-anatomical-hemispherectomy-for-rasmussen-s-encephalitis-treatment-a-case-report
#11
Jaron C Sanchez, Markeeta T Belmar, Jason C Sanchez, Kenny Nguygen
Hemispherectomy is a neurosurgical procedure that is frequently performed in pediatric patients diagnosed with Rasmussen's encephalitis. Postoperative complications include immediate complications such as hydrocephalus and hemorrhage and behavioral complications such as language impairments and contralateral weakness. However, there are limited studies or case reports that address the potential endocrinopathies associated with this and other pediatric epileptic surgeries. This case report describes the endocrinopathies following an anatomical hemispherectomy procedure...
February 2024: Curēus
https://read.qxmd.com/read/38464824/comparing-the-long-term-cardiovascular-outcomes-of-lumbo-peritoneal-ventriculo-peritoneal-or-non-shunting-treatment-after-idiopathic-normal-pressure-hydrocephalus-a-nationwide-retrospective-cohort-study
#12
JOURNAL ARTICLE
Cheng-Di Chiu, Po-Fan Chiu, Chih-Ying Wu, Hei-Tung Yip, You-Pen Chiu, Hui-Ru Ji, Kai-Cheng Hsu, Fuu-Jen Tsai, Robert Chen-Hao Chang
Purpose: With advances in medical technology, the average lifespan has increased, leading to a growing significance of idiopathic normal pressure hydrocephalus (iNPH), particularly in the elderly population. Most patients with iNPH have been treated either with ventriculo-peritoneal shunts (VPS) or conservative measures. However, lumbo-peritoneal shunts (LPS) have emerged as an alternative treatment option for iNPH in recent decades, extensive research still lacks comparing outcomes with LPS to those with VPS or non-surgical treatment...
2024: International Journal of Medical Sciences
https://read.qxmd.com/read/38457814/risk-factors-for-postoperative-ventriculoperitoneal-shunt-requirement-in-pediatric-patients-with-brain-tumors-invading-or-adjacent-to-csf-circulation-pathways
#13
JOURNAL ARTICLE
Zesheng Ying, Wei Yang, Nijia Zhang, Hailang Sun, Di Zhang, Baojin Shang, Jiashu Chen, Ming Ge
OBJECTIVE: Hydrocephalus is a common comorbidity of brain tumors in children that may persist following brain tumor resection. This study aimed to explore perioperative risk factors associated with postoperative ventriculoperitoneal shunt (VPS) placement for tumors located at or adjacent to the CSF circulation pathway. METHODS: Patients aged 0-18 years with tumors invading or adjacent to the CSF circulation pathways who underwent brain tumor resection between October 2015 and September 2021 were included in this study...
March 8, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38457812/predictors-and-timing-of-hydrocephalus-treatment-in-patients-undergoing-prenatal-versus-postnatal-surgery-for-myelomeningocele
#14
JOURNAL ARTICLE
Sasidhar Karuparti, Ashley Dunbar, Kaamya Varagur, Kavya Sudanagunta, Mark Mingo, Katherine H Bligard, Anthony Odibo, Jesse Vrecenak, Sean McEvoy, David Limbrick, Lindsay Peglar Marsala, Jagruti Anadkat, Ali Mian, Jennifer M Strahle
OBJECTIVE: Although hydrocephalus rates have decreased with intrauterine surgery for myelomeningocele (MMC), 40%-85% of children with MMC still go on to develop hydrocephalus. Prenatal ventricle size is known to be associated with later development of hydrocephalus; however, it is not known how prediction measures or timing of hydrocephalus treatment differ between pre- and postnatal surgery for MMC. The goal of this study was to determine anatomical, clinical, and radiological characteristics that are associated with the need for and timing of hydrocephalus treatment in patients with MMC...
March 8, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38457805/head-growth-in-patients-with-myelomeningocele-treated-with-prenatal-and-postnatal-surgery
#15
JOURNAL ARTICLE
Sasidhar Karuparti, Tracy M Flanders, Ashley Dunbar, Kaamya Varagur, Jennifer M Strahle
OBJECTIVE: The need for permanent CSF diversion is lower in patients who have undergone prenatal surgery for myelomeningocele (MMC) than in those who have undergone postnatal closure. Differences in brain development and head growth between treatment groups are not known, particularly for those who do not require surgical treatment for hydrocephalus. The objective of this study was to determine differences in head growth and to generate MMC-specific head circumference (HC) growth curves for patients who underwent either prenatal or postnatal surgery...
March 8, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38452929/risk-factors-for-shunt-dependent-hydrocephalus-after-spontaneous-subarachnoid-hemorrhage
#16
JOURNAL ARTICLE
Loreto Esteban Estallo, Juan Casado Pellejero, Silvia Vázquez Sufuentes, Laura Beatriz López López, David Fustero de Miguel, Luis Manuel González Martínez
INTRODUCTION: Subarachnoid hemorrhage (SAH) is one of the most frequent neurosurgical emergencies, most of them due to intracranial aneurysm rupture. Hydrocephalus is a prevalent complication with a high rate of complications. The aims of this study are to identify predictors of shunt-dependent hydrocephalus following aneurysmal SAH and to quantify the complications arising from ventriculoperitoneal shunts. METHODS: This study is about an observational retrospective analytic study of the patients with spontaneous SAH admitted to Miguel Servet Universitary Hospital between 2017 and 2022...
March 5, 2024: Neurocirugía (English Edition)
https://read.qxmd.com/read/38451042/-cryptococcal-meningitis-associated-with-hydrocephalus-in-an-immunocompetent-patient
#17
Julián Castro Castro, María Dolores Díaz López
Cryptococcal meningitis is an infrequent infection with high morbidity and mortality. Its presentation in immunocompetent patients is rare. We present the case of a 67-year-old male who was admitted for subacute symptoms of gait disturbance and urinary incontinence. Neurological examination revealed inability to stand and memory impairment. Cranial imaging showed obstructive tetraventricular hydrocephalus with areas of gliosis in the cerebellar peduncles. Endoscopic treatment of hydrocephalus was performed and cerebrospinal fluid samples taken revealing the growth of Cryptococcus neoformans...
March 7, 2024: Anales del Sistema Sanitario de Navarra
https://read.qxmd.com/read/38449361/congenital-toxoplasmosis-and-long-term-outcomes
#18
JOURNAL ARTICLE
Ozlem Ozgur Gundeslioglu, Zeliha Haytoglu, Ebru Esen, Derya Alabaz, Ummuhan Cay, Ferda Ozlu, Filiz Kibar, Salih Cetiner
OBJECTIVE: Congenital toxoplasmosis (CT) can have severe early and late sequelae in children. In this study, we aimed to evaluate the demographic, clinical, treatment characteristics of patients diagnosed with congenital Toxoplasma infection and to highlight the long-term complications of the patients. METHODS: Patients with CT were included in this study who were followed between 2010 and 2022 in Cukurova University Medical Faculty Hospital. Demographic, clinical and treatment characteristics were searched retrospectively...
March 5, 2024: Türkiye Parazitolojii Dergisi
https://read.qxmd.com/read/38444692/pleomorphic-adenoma-of-the-parotid-gland-concomitant-with-tuberculosis-infection-a-case-report-and-review-of-the-literature
#19
Dorra Chiboub, Nadia Romdhane, Esma Jameleddine, Emna Rejeb, Fatma Khanchel, Raja Jouini, Imen Zoghlami, Safa Nefzaoui, Ines Hariga, Chiraz Mbarek
Tuberculosis of the salivary glands and particularly of the parotid gland is a localization that remains rare even in endemic countries. The association of intra parotid tuberculosis with a benign tumor has been found only in rare cases in literature. A 50-year-old woman with a history of normal pressure hydrocephalus treated surgically, non-smoker, presented with a right parotid swelling progressively increasing in size for 3 years. Clinical examination revealed a 4 cm long, firm, mobile, painless parotid swelling without inflammatory signs and without accessory lymphadenopathy...
2024: SAGE Open Medical Case Reports
https://read.qxmd.com/read/38443004/comparative-analysis-of-hemispherotomy-in-adults-versus-children-a-prospective-observational-series
#20
JOURNAL ARTICLE
Jitin Bajaj, Sarat P Chandra, Bhargavi Ramanujam, Heri Subianto, Shabari Girishan, Ramesh Doddamani, Mohit Agrawal, Raghu Samala, Rekha Dwivedi, Kapil Chaudhary, Ajay Garg, Madhavi Tripathi, C S Bal, Ashima Nehra, Mehar C Sharma, Manjari Tripathi
BACKGROUND: Hemispherotomy (HS) is an effective treatment for unilateral hemispheric onset epilepsy. There are few publications for HS in adults, and there is no series comparing adults and pediatric patients of HS. OBJECTIVE: To compare the hemispherotomies done in adult patients with pediatric ones in terms of efficacy and safety. METHODS: Data was prospectively collected for HS patients (up to 18 years and more) from Aug 2014 to Aug 2018...
January 1, 2024: Neurology India
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