keyword
MENU ▼
Read by QxMD icon Read
search

hi-c OR hic

keyword
https://www.readbyqxmd.com/read/30120652/znf143-is-a-regulator-of-chromatin-loop
#1
Zi Wen, Zhi-Tao Huang, Ran Zhang, Cheng Peng
It is known that transcription factor ZNF143 frequently co-binds with CTCF-Cohesin complex in the anchor regions of chromatin loops. However, there is currently no genome-wide experiment to explore the functional roles of ZNF143 in chromatin loops. In this work, we used both computational and experimental analyses to investigate the regulatory effect of ZNF143 on chromatin loops. By jointly analyzing the ZNF143 and CTCF motifs underlying the isolated ZNF143-binding sites, ZNF143-CTCF co-binding sites and ZNF143-CTCF-RAD21 co-binding sites, our result shows that the ZNF143-CTCF-RAD21 co-binding sites are enriched with CTCF motifs but depleted of Znf143 motifs, implying that the CTCF but not ZNF143 may directly binds to the genome and thus ZNF143 may act as a cofactor instead of pioneer factor of ZNF143-CTCF-Cohesin complex...
August 17, 2018: Cell Biology and Toxicology
https://www.readbyqxmd.com/read/30120618/high-and-intensive-care-in-psychiatry-validating-the-hic-monitor-as-a-tool-for-assessing-the-quality-of-psychiatric-intensive-care-units
#2
A L van Melle, Y Voskes, H C W de Vet, J van der Meijs, C L Mulder, G A M Widdershoven
This study aims to validate the HIC monitor as a model-fidelity scale to the High and Intensive Care (HIC) model, a recently developed model for acute psychiatric wards. To assess the psychometric properties of the HIC monitor, 37 audits were held on closed inpatient wards at 20 psychiatric hospitals in the Netherlands. Interrater reliability, construct validity and content validity were examined. Our results suggest that the HIC monitor has good psychometric properties. It can be used as a tool for assessing the implementation of the HIC model on acute psychiatric wards in the Netherlands, and for quality assessment and improvement...
August 17, 2018: Administration and Policy in Mental Health
https://www.readbyqxmd.com/read/30116294/numerical-low-back-booster-analysis-on-a-6-year-old-infant-during-a-frontal-crash-test
#3
I L Cruz-Jaramillo, C R Torres-San-Miguel, O Cortes-Vásquez, L Martínez-Sáez
This work studies descriptively the Head Injury Criterion (HIC) and Chest Severity Index (CSI), with a finite element model of the Hybrid III dummy type, for six-year-old subjects in a frontal vehicular collision, using the low-back booster (LBB) passive safety system. The vehicle seats and the passive safety systems were modelled in CAD (computer aided design) software. Then, the elements were analysed by the finite element method (FEM) in LS-DYNA® software. The boundary conditions were established for each study, according to the regulations established by the Federal Motor Vehicle Safety Standard (FMVSS), following the FMVSS 213 standard...
2018: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/30115876/hepatoprotective-effects-of-mhy3200-on-high-fat-diet-induced-non-alcoholic-fatty-liver-disease-in-rats
#4
Min Jo Kim, Chan Hum Park, Dae Hyun Kim, Min Hi Park, Kyung Chul Park, Min Kyung Hyun, A Kyoung Lee, Hyung Ryong Moon, Hae Young Chung
This study investigated the effects of 2-(4-(5-chlorobenzo[ d ]thiazol-2-yl)phenoxy)-2,2-difluoroacetic acid (MHY3200) on high-fat diet (HFD)-induced hepatic lipid accumulation and inflammation. The measurement of peroxisome proliferator-activated receptor (PPAR)α activity by using a luciferase assay indicated that MHY3200 was more potent than a known PPARα agonist, WY14643, in AC2F cells. Six-month-old male SD rats were fed chow or HFD for 1 month, and after, with or without added MHY3200 (1 or 2 mg/kg/day) for 4 weeks...
August 16, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/30115783/shifting-the-limits-in-wheat-research-and-breeding-using-a-fully-annotated-reference-genome
#5
Rudi Appels, Kellye Eversole, Catherine Feuillet, Beat Keller, Jane Rogers, Nils Stein, Curtis J Pozniak, Nils Stein, Frédéric Choulet, Assaf Distelfeld, Kellye Eversole, Jesse Poland, Jane Rogers, Gil Ronen, Andrew G Sharpe, Curtis Pozniak, Gil Ronen, Nils Stein, Omer Barad, Kobi Baruch, Frédéric Choulet, Gabriel Keeble-Gagnère, Martin Mascher, Andrew G Sharpe, Gil Ben-Zvi, Ambre-Aurore Josselin, Nils Stein, Martin Mascher, Axel Himmelbach, Frédéric Choulet, Gabriel Keeble-Gagnère, Martin Mascher, Jane Rogers, François Balfourier, Juan Gutierrez-Gonzalez, Matthew Hayden, Ambre-Aurore Josselin, ChuShin Koh, Gary Muehlbauer, Raj K Pasam, Etienne Paux, Curtis J Pozniak, Philippe Rigault, Andrew G Sharpe, Josquin Tibbits, Vijay Tiwari, Frédéric Choulet, Gabriel Keeble-Gagnère, Martin Mascher, Ambre-Aurore Josselin, Jane Rogers, Manuel Spannagl, Frédéric Choulet, Daniel Lang, Heidrun Gundlach, Georg Haberer, Gabriel Keeble-Gagnère, Klaus F X Mayer, Danara Ormanbekova, Etienne Paux, Verena Prade, Hana Šimková, Thomas Wicker, Frédéric Choulet, Manuel Spannagl, David Swarbreck, Hélène Rimbert, Marius Felder, Nicolas Guilhot, Heidrun Gundlach, Georg Haberer, Gemy Kaithakottil, Jens Keilwagen, Daniel Lang, Philippe Leroy, Thomas Lux, Klaus F X Mayer, Sven Twardziok, Luca Venturini, Rudi Appels, Hélène Rimbert, Frédéric Choulet, Angéla Juhász, Gabriel Keeble-Gagnère, Frédéric Choulet, Manuel Spannagl, Daniel Lang, Michael Abrouk, Georg Haberer, Gabriel Keeble-Gagnère, Klaus F X Mayer, Thomas Wicker, Frédéric Choulet, Thomas Wicker, Heidrun Gundlach, Daniel Lang, Manuel Spannagl, Daniel Lang, Manuel Spannagl, Rudi Appels, Iris Fischer, Cristobal Uauy, Philippa Borrill, Ricardo H Ramirez-Gonzalez, Rudi Appels, Dominique Arnaud, Smahane Chalabi, Boulos Chalhoub, Frédéric Choulet, Aron Cory, Raju Datla, Mark W Davey, Matthew Hayden, John Jacobs, Daniel Lang, Stephen J Robinson, Manuel Spannagl, Burkhard Steuernagel, Josquin Tibbits, Vijay Tiwari, Fred van Ex, Brande B H Wulff, Curtis J Pozniak, Stephen J Robinson, Andrew G Sharpe, Aron Cory, Moussa Benhamed, Etienne Paux, Abdelhafid Bendahmane, Lorenzo Concia, David Latrasse, Jane Rogers, John Jacobs, Michael Alaux, Rudi Appels, Jan Bartoš, Arnaud Bellec, Hélène Berges, Jaroslav Doležel, Catherine Feuillet, Zeev Frenkel, Bikram Gill, Abraham Korol, Thomas Letellier, Odd-Arne Olsen, Hana Šimková, Kuldeep Singh, Miroslav Valárik, Edwin van der Vossen, Sonia Vautrin, Song Weining, Abraham Korol, Zeev Frenkel, Tzion Fahima, Vladimir Glikson, Dina Raats, Jane Rogers, Vijay Tiwari, Bikram Gill, Etienne Paux, Jesse Poland, Jaroslav Doležel, Jarmila Číhalíková, Hana Šimková, Helena Toegelová, Jan Vrána, Pierre Sourdille, Benoit Darrier, Rudi Appels, Manuel Spannagl, Daniel Lang, Iris Fischer, Danara Ormanbekova, Verena Prade, Delfina Barabaschi, Luigi Cattivelli, Pilar Hernandez, Sergio Galvez, Hikmet Budak, Burkhard Steuernagel, Jonathan D G Jones, Kamil Witek, Brande B H Wulff, Guotai Yu, Ian Small, Joanna Melonek, Ruonan Zhou, Angéla Juhász, Tatiana Belova, Rudi Appels, Odd-Arne Olsen, Kostya Kanyuka, Robert King, Kirby Nilsen, Sean Walkowiak, Curtis J Pozniak, Richard Cuthbert, Raju Datla, Ron Knox, Krysta Wiebe, Daoquan Xiang, Antje Rohde, Timothy Golds, Jaroslav Doležel, Jana Čížková, Josquin Tibbits, Hikmet Budak, Bala Ani Akpinar, Sezgi Biyiklioglu, Gary Muehlbauer, Jesse Poland, Liangliang Gao, Juan Gutierrez-Gonzalez, Amidou N'Daiye, Jaroslav Doležel, Hana Šimková, Jarmila Číhalíková, Marie Kubaláková, Jan Šafář, Jan Vrána, Hélène Berges, Arnaud Bellec, Sonia Vautrin, Michael Alaux, Françoise Alfama, Anne-Françoise Adam-Blondon, Raphael Flores, Claire Guerche, Thomas Letellier, Mikaël Loaec, Hadi Quesneville, Curtis J Pozniak, Andrew G Sharpe, Sean Walkowiak, Hikmet Budak, Janet Condie, Jennifer Ens, ChuShin Koh, Ron Maclachlan, Yifang Tan, Thomas Wicker, Frédéric Choulet, Etienne Paux, Adriana Alberti, Jean-Marc Aury, François Balfourier, Valérie Barbe, Arnaud Couloux, Corinne Cruaud, Karine Labadie, Sophie Mangenot, Patrick Wincker, Bikram Gill, Gaganpreet Kaur, Mingcheng Luo, Sunish Sehgal, Kuldeep Singh, Parveen Chhuneja, Om Prakash Gupta, Suruchi Jindal, Parampreet Kaur, Palvi Malik, Priti Sharma, Bharat Yadav, Nagendra K Singh, JitendraP Khurana, Chanderkant Chaudhary, Paramjit Khurana, Vinod Kumar, Ajay Mahato, Saloni Mathur, Amitha Sevanthi, Naveen Sharma, Ram Sewak Tomar, Jane Rogers, John Jacobs, Michael Alaux, Arnaud Bellec, Hélène Berges, Jaroslav Doležel, Catherine Feuillet, Zeev Frenkel, Bikram Gill, Abraham Korol, Edwin van der Vossen, Sonia Vautrin, Bikram Gill, Gaganpreet Kaur, Mingcheng Luo, Sunish Sehgal, Jan Bartoš, Kateřina Holušová, Ondřej Plíhal, Matthew D Clark, Darren Heavens, George Kettleborough, Jon Wright, Miroslav Valárik, Michael Abrouk, Barbora Balcárková, Kateřina Holušová, Yuqin Hu, Mingcheng Luo, Elena Salina, Nikolai Ravin, Konstantin Skryabin, Alexey Beletsky, Vitaly Kadnikov, Andrey Mardanov, Michail Nesterov, Andrey Rakitin, Ekaterina Sergeeva, Hirokazu Handa, Hiroyuki Kanamori, Satoshi Katagiri, Fuminori Kobayashi, Shuhei Nasuda, Tsuyoshi Tanaka, Jianzhong Wu, Rudi Appels, Matthew Hayden, Gabriel Keeble-Gagnère, Philippe Rigault, Josquin Tibbits, Odd-Arne Olsen, Tatiana Belova, Federica Cattonaro, Min Jiumeng, Karl Kugler, Klaus F X Mayer, Matthias Pfeifer, Simen Sandve, Xu Xun, Bujie Zhan, Hana Šimková, Michael Abrouk, Jacqueline Batley, Philipp E Bayer, David Edwards, Satomi Hayashi, Helena Toegelová, Zuzana Tulpová, Paul Visendi, Song Weining, Licao Cui, Xianghong Du, Kewei Feng, Xiaojun Nie, Wei Tong, Le Wang, Philippa Borrill, Heidrun Gundlach, Sergio Galvez, Gemy Kaithakottil, Daniel Lang, Thomas Lux, Martin Mascher, Danara Ormanbekova, Verena Prade, Ricardo H Ramirez-Gonzalez, Manuel Spannagl, Nils Stein, Cristobal Uauy, Luca Venturini, Nils Stein, Rudi Appels, Kellye Eversole, Jane Rogers, Philippa Borrill, Luigi Cattivelli, Frédéric Choulet, Pilar Hernandez, Kostya Kanyuka, Daniel Lang, Martin Mascher, Kirby Nilsen, Etienne Paux, Curtis J Pozniak, Ricardo H Ramirez-Gonzalez, Hana Šimková, Ian Small, Manuel Spannagl, David Swarbreck, Cristobal Uauy
An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development...
August 17, 2018: Science
https://www.readbyqxmd.com/read/30113897/inferring-spatial-organization-of-individual-topologically-associated-domains-via-piecewise-helical-model
#6
Rongrong Zhang, Ming Hu, Yu Michael Zhu, Zhaohui Steve Qin, Ke Deng, Jun Liu
The recently developed Hi-C technology enables a genome-wide view of chromosome spatial organizations, and has shed deep insights into genome structure and genome function. However, multiple sources of uncertainties make downstream data analysis and interpretation challenging. Specifically, statistical models for inferring three-dimensional (3D) chromosomal structure from Hi-C data are far from their maturity. Most existing methods are highly over-parameterized, lacking clear interpretations, and sensitive to outliers...
August 15, 2018: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/30112334/robotic-radiosurgery-treatment-in-liver-tumors-early-experience-from-an-indian-center
#7
Debnarayan Dutta, Sathiya Krishnamoorthy, H Sudahar, M Muthukumaran, T Ramkumar, Jayraj Govindraj
Purpose: The purpose of this study is to report CyberKnife experience in hepatocellular carcinoma (HCC) and liver metastasis (LM). Materials and Methods: Fifty liver lesions in 31 consecutive patients with liver lesion [mean age 54.5 years (range 32-81 years), 77% were male patient, GTV <10cc in 5 patients, 11-90cc in 18 & >90cc in 8 patients respectively. Eighty percentage (25/31) had prior treatment (chemotherapy 18 patient & TACE in 7 patients)...
July 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/30111883/decoding-topologically-associating-domains-with-ultra-low-resolution-hi-c-data-by-graph-structural-entropy
#8
Angsheng Li, Xianchen Yin, Bingxiang Xu, Danyang Wang, Jimin Han, Yi Wei, Yun Deng, Ying Xiong, Zhihua Zhang
Submegabase-size topologically associating domains (TAD) have been observed in high-throughput chromatin interaction data (Hi-C). However, accurate detection of TADs depends on ultra-deep sequencing and sophisticated normalization procedures. Here we propose a fast and normalization-free method to decode the domains of chromosomes (deDoc) that utilizes structural information theory. By treating Hi-C contact matrix as a representation of a graph, deDoc partitions the graph into segments with minimal structural entropy...
August 15, 2018: Nature Communications
https://www.readbyqxmd.com/read/30110240/homology-modeling-and-structure-based-design-improve-hydrophobic-interaction-chromatography-behavior-of-integrin-binding-antibodies
#9
Arif Jetha, Nels Thorsteinson, Yazen Jmeian, Ajitha Jeganathan, Patricia Giblin, Johan Fransson
Monoclonal antibody (mAb) candidates from high-throughput screening or binding affinity optimization often contain mutations leading to liabilities for further development of the antibody, such as aggregation-prone regions and lack of solubility. In this work, we optimized a candidate integrin α11-binding mAb for developability using molecular modeling, rational design, and hydrophobic interaction chromatography (HIC). A homology model of the parental mAb Fv region was built, and this revealed hydrophobic patches on the surface of the complementarity-determining region loops...
August 15, 2018: MAbs
https://www.readbyqxmd.com/read/30109620/deciphering-3d-organization-of-chromosomes-using-hi-c-data
#10
Andreas Hofmann, Dieter W Heermann
In order to interpret data from Hi-C studies genome-wide contact probability maps need to be translated into models of functional 3D genome organization. Here, we first present an overview of computational methods to analyze contact probability maps in terms of features such as the level and shape of compartmentalization. Next, we describe approaches to modeling 3D genome organization based on Hi-C data.
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/30109603/processing-and-analysis-of-hi-c-data-on-bacteria
#11
Andreas Hofmann, Dieter W Heermann
The study of three-dimensional genome organization has recently gained much attention in the context of novel techniques for detecting genome-wide contacts using next-generation sequencing. These genome-wide chromosome conformation capture-based methods, such as Hi-C, give a deep topological insight into the architecture of the genome inside the cell. This chapter reviews the steps to process next-generation Hi-C sequencing data to generate a final contact probability map. We describe these steps using publicly available Hi-C datasets of different bacteria...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/30109602/determination-of-the-3d-genome-organization-of-bacteria-using-hi-c
#12
Frédéric G Crémazy, Fatema-Zahra M Rashid, James R Haycocks, Lisa E Lamberte, David C Grainger, Remus T Dame
The spatial organization of genomes is based on their hierarchical compartmentalization in topological domains. There is growing evidence that bacterial genomes are organized into insulated domains similar to the Topologically Associating Domains (TADs) detected in eukaryotic cells. Chromosome conformation capture (3C) technologies are used to analyze in vivo DNA proximity based on ligation of distal DNA segments crossed-linked by bridging proteins. By combining 3C and high-throughput sequencing, the Hi-C method reveals genome-wide interactions within topological domains and global genome structure as a whole...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/30107523/a-near-complete-chromosome-scale-assembly-of-the-black-raspberry-rubus-occidentalis-genome
#13
Robert VanBuren, Ching Man Wai, Marivi Colle, Jie Wang, Shawn Sullivan, Jill M Bushakra, Ivan Liachko, Kelly J Vining, Michael Dossett, Chad E Finn, Rubina Jibran, David Chagné, Kevin Childs, Patrick P Edger, Todd C Mockler, Nahla V Bassil
Background: The fragmented nature of most draft plant genomes has hindered downstream gene discovery, trait mapping for breeding, and other functional genomics applications. There is a pressing need to improve or finish draft plant genome assemblies. Findings: Here we present a chromosome-scale assembly of the black raspberry genome using single-molecule real-time (SMRT) PacBio sequencing and Hi-C genome scaffolding. The updated V3 assembly has a contig N50 of 5...
August 9, 2018: GigaScience
https://www.readbyqxmd.com/read/30102940/insertion-responsive-microneedles-for-rapid-intradermal-delivery-of-canine-influenza-vaccine
#14
In-Jeong Choi, Aram Kang, Myun-Hwan Ahn, Hyesun Jun, Seung-Ki Baek, Jung-Hwan Park, Woonsung Na, Seong-O Choi
In this study, we present transcutaneous influenza vaccination using a novel tip-separable microneedle system called insertion-responsive microneedles (IRMNs). IRMNs are composed of dissolvable hyaluronic acid (HA) tips and biocompatible polycaprolactone (PCL) bases, the tip of which is instantly separated from the base during microneedle insertion and retraction. Vaccine antigens derived from canine influenza virus (A/canine/VC378/2012; H3N2) were successfully coated on HA tips by rapidly freezing the tips prior to coating...
August 10, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/30101322/the-chromosome-level-genome-assemblies-of-two-rattans-calamus-simplicifolius-and-daemonorops-jenkinsiana
#15
Hansheng Zhao, Songbo Wang, Jiongliang Wang, Chuanhai Chen, Shijie Hao, Lianfu Chen, Benhua Fei, Kai Han, Rongsheng Li, Chengcheng Shi, Huayu Sun, Sining Wang, Hao Xu, Kebin Yang, Xiurong Xu, Xuemeng Shan, Jingjing Shi, Aiqin Feng, Guangyi Fan, Xin Liu, Shancen Zhao, Chi Zhang, Qiang Gao, Zhimin Gao, Zehui Jiang
Background: Calamus simplicifolius and Daemonorops jenkinsiana are two representative rattans, the most significant material sources for the rattan industry. However, the lack of reference genome sequences is a major obstacle for basic and applied biology on rattan. Findings: We produced two chromosome-level genome assemblies of C. simplicifolius and D. jenkinsiana using Illumina, PacBio, and Hi-C sequencing data. A total of ∼730 Gb and ∼682 Gb of raw data covered the predicted genome lengths (∼1...
August 7, 2018: GigaScience
https://www.readbyqxmd.com/read/30100828/finite-element-analysis-of-impact-for-helmeted-and-non-helmeted-head
#16
Ievgen Levadnyi, Jan Awrejcewicz, Yan Zhang, Márcio Fagundes Goethel, Yaodong Gu
This study investigated the influence of human head impact on the severity of traumatic brain injury. Simulation of the dynamic impact of a human head was performed using FEM (finite element method) and employing HIC (Head Injury Criterion). The study of traumatic brain injury included impacts with the occiput, temporal, forehead, and parietal part of the head, and the impact velocity at the surface ranged from 1 to 7 m/s. The following characteristics were considered and analyzed in the simulation: duration of the impact, intracranial pressure, HIC, and change in accelerations at the center of gravity of the brain...
2018: Journal of Medical and Biological Engineering
https://www.readbyqxmd.com/read/30100265/in-vivo-evidence-for-atpase-dependent-dna-translocation-by-the-bacillus-subtilis-smc-condensin-complex
#17
Xindan Wang, Anna C Hughes, Hugo B Brandão, Benjamin Walker, Carrie Lierz, Jared C Cochran, Martha G Oakley, Andrew C Kruse, David Z Rudner
Structural maintenance of chromosomes (SMC) complexes shape the genomes of virtually all organisms, but how they function remains incompletely understood. Recent studies in bacteria and eukaryotes have led to a unifying model in which these ring-shaped ATPases act along contiguous DNA segments, processively enlarging DNA loops. In support of this model, single-molecule imaging experiments indicate that Saccharomyces cerevisiae condensin complexes can extrude DNA loops in an ATP-hydrolysis-dependent manner in vitro...
August 2, 2018: Molecular Cell
https://www.readbyqxmd.com/read/30098484/systematic-reviews-of-economic-burden-and-health-related-quality-of-life-in-patients-with-acute-myeloid-leukemia
#18
REVIEW
Rachel Bosshard, Karl O'Reilly, Stephen Ralston, Shkun Chadda, David Cork
BACKGROUND: Acute myeloid leukemia (AML) is a rare hematologic malignancy largely affecting older adults. Comorbidities may compromise fitness and eligibility for high-intensity chemotherapy (HIC). This study presents the results of two systematic reviews (SRs) assessing (1) the impact of AML and current treatments on health-related quality of life (HRQoL), and (2) the economic burden and cost drivers of AML in patients who are ineligible for HIC. METHODS: Electronic searches (MEDLINE, EMBASE, EconLit, Cochrane library) were supplemented with manual searching of conference, utility, and HTA databases...
July 18, 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/30096023/recent-patterns-of-multimorbidity-among-older-adults-in-high-income-countries
#19
Richard Ofori-Asenso, Ken Lee Chin, Andrea J Curtis, Ella Zomer, Sophia Zoungas, Danny Liew
Population aging along with the rising burden of chronic medical conditions (CMCs) is challenging the sustainability of health care systems globally. The authors sought to characterize contemporary patterns of multimorbidity among older adults (aged ≥65 years) in high-income countries (HICs). Medline, EMBASE, CINAHL, PsycINFO, and Web of Science were searched in January 2018 for English-language articles that reported the prevalence of multimorbidity (defined as co-occurrence of ≥2 CMCs in an individual without defining an index disease) among older adults in HICs, or the proportions with ≥3 or ≥5 CMCs...
August 10, 2018: Population Health Management
https://www.readbyqxmd.com/read/30095453/health-information-counselors-a-new-profession-for-the-age-of-big-data
#20
Amelia Fiske, Alena Buyx, Barbara Prainsack
Health care is increasingly data-driven. Concurrently, there are growing concerns that health professionals lack the time and training to guide patients through the growing medical "data jungle." In the age of big data, ever wider domains of people's lives are "datafied," which renders ever more information-at least in principle-usable for health care purposes. Turning data into meaningful information for clinical practice-and deciding what data or information should not be used for this purpose-requires a significant amount of time, resources, and skill...
August 7, 2018: Academic Medicine: Journal of the Association of American Medical Colleges
keyword
keyword
163782
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"