keyword
https://read.qxmd.com/read/38546959/a-case-of-hypertensive-emergency-with-alveolar-hemorrhage-and-thrombotic-microangiopathy
#1
JOURNAL ARTICLE
Yoshifumi Ubara, Shigekazu Kurihara, Yoshiki Tsuchiya, Yuki Oba, Daisuke Ikuma, Hiroki Mizuno, Masayuki Yamanouchi, Tatsuya Suwabe, Atsuko Imase, Nobumitsu Shibata, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Kentaro Ogata, Naoki Sawa
A 28-year-old woman with a 5-year history of untreated hypertension was admitted for respiratory distress, hemoptysis, and retinopathy. Computed tomography showed diffuse plaques in both lung fields. Acute kidney injury, hemolytic anemia, and thrombocytopenia were noted. Kidney biopsy showed thrombosis with fibrinoid necrosis and edematous intimal thickening and luminal narrowing of the small renal artery, indicating thrombotic microangiopathy; the majority of glomeruli were collapsed. After 8 weeks of treatment with antihypertensive drugs, serum creatinine decreased to 1...
March 28, 2024: CEN Case Reports
https://read.qxmd.com/read/38533152/navigating-the-challenges-of-delayed-subdural-hemorrhage-and-covid-19-a-case-report
#2
Saleh S Al Qahtani, Dunya Alfaraj, Mohammed O Alzayer, Zainab Juma, Mohamed Abdulla, Husain Faraj, Abdulla Juma, Mohamed M Moussa
The delayed onset of posttraumatic subdural hemorrhage (SDH) represents non-specific clinical features, complicating the diagnostic process, especially in individuals predisposed due to pre-existing risk factors and comorbidities. This case report delineates the medical trajectory of a 61-year-old female patient who sustained a traumatic fall, initially displaying neither clinical nor radiological signs indicative of hemorrhage. However, three weeks post-injury, she developed altered mental status, cephalgia, and emesis...
February 2024: Curēus
https://read.qxmd.com/read/38529428/novel-use-of-clonidine-patch-to-treat-tizanidine-withdrawal
#3
Aaron B Deutsch, Clare F Hartman, Curtis P Flaherty, Natalie E Ebeling-Koning, Gillian A Beauchamp, Kenneth D Katz
Tizanidine is commonly prescribed for muscle spasticity and pain. Yet, withdrawal is rarely reported. Tizanidine stimulates presynaptic α-2 adrenergic and imidazoline receptors decreasing norepinephrine release. Abrupt cessation can cause withdrawal. Current treatment strategies include tapering oral tizanidine or substituting oral clonidine. A 52-year-old male with a history of hypertension, diabetes, coronary artery disease, and chronic back pain presented with altered mental status, agitation, hypertensive emergency (blood pressure: 250/145 mmHg), and tachycardia...
February 2024: Curēus
https://read.qxmd.com/read/38528015/the-characteristics-and-risk-factors-of-fatal-falls-among-adults-aged-60-and-above-in-southwest-china
#4
JOURNAL ARTICLE
Rui Deng, Benyan Li, Mingfang Qin, Xinyi Yu, Junli Sun, Feng Jiao, Yuan Huang
Falls constitute a leading cause of unintentional injury deaths among older adults. This study aimed to examine the comprehensive characteristics of fatal falls among older individuals in Yunnan Province, China, to highlight the challenges faced in elderly care. A total of 22,798 accidental fall-related deaths were extracted from China's National Disease Surveillance Points System aged 60 and above between 2015 and 2019. Quantitative and textual data were analyzed to assess the incidence rates of initiating factors, locations, symptoms, and overall survival (OS) outcomes after falling...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38508875/-hypertensive-emergency-as-the-debut-of-paraneoplastic-cushing-syndrome
#5
E Rubio González, M de Valdenebro Recio, M I Galán Fernández
We present the case of a patient with a history of renal-vascular hypertension treated with stent one year previously, who attended the emergency room due to hypertensive emergency and dyspnea. Once the first suspicion of renal artery restenosis was ruled out with CT angiography, the study was completed, confirming the diagnosis of lung cancer through imaging and pathological anatomy. In the hormonal study, elevation of ACTH, hypercortisolism and analytical data of hyperaldosteronism were detected. With the final diagnosis of Cushing's syndrome secondary to ectopic production of ACTH, medical treatment was started, without being able to receive anything else due to the death of the patient after a few days...
March 19, 2024: Hipertensión y Riesgo Vascular
https://read.qxmd.com/read/38507508/flow-disturbances-competing-interests-in-a-case-of-hypertensive-emergency
#6
JOURNAL ARTICLE
Matthew R Alexander, Aaron W Aday, Julia Lewis, Christine J Deyholos, James M Luther
No abstract text is available yet for this article.
April 2024: Hypertension
https://read.qxmd.com/read/38411625/blood-pressure-elevation-in-erenumab-treated-patients-with-migraine-a-retrospective-real-world-experience
#7
JOURNAL ARTICLE
Nikita Chhabra, Carolyn Mead-Harvey, Christopher A Dodoo, Courtney Iser, Hallie Taylor, Hira Chaudhary, Aimen Vanood, David W Dodick
BACKGROUND: Erenumab is a monoclonal antibody that targets the calcitonin gene-related peptide (CGRP) receptor and is approved for the preventative treatment of migraine in adults. CGRP is involved in the regulation of vasomotor tone under physiologic and pathologic conditions, including hypertension. While there has not been evidence of hypertension in preclinical models or clinical trials, post-marketing data suggest erenumab may be associated with hypertension. This led to a warning in the United States Food and Drug Administration prescribing information for erenumab...
February 27, 2024: Headache
https://read.qxmd.com/read/38410306/comparison-of-risk-of-stroke-in-patients-with-and-without-depression-a-systematic-review-and-meta-analysis
#8
REVIEW
Manisha Kanumuri, Areeba Khan, Asfia Neshat, Goutham Alapati, Gopi Sairam Reddy Mulaka, Nimra Nisar, Saima Batool, Fnu Arti
Individuals with depression face an elevated stroke risk, marked by an unfavorable prognosis. This meta-analysis aims to determine the impact of depression on stroke risk. The current meta-analysis was conducted using the guidelines established by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We selected studies through a systematic review of electronic databases, including PubMed, EMBASE, and CINAHL from January 2011 to January 2023. Google Scholar was utilized to identify supplementary studies...
January 2024: Curēus
https://read.qxmd.com/read/38406777/clinical-and-echocardiographic-findings-in-patients-with-covid-19-across-different-severity-levels
#9
JOURNAL ARTICLE
Ihor Hryzhak, Oleksandra Pryshliak, Taras Kobryn, Sergiy Fedorov, Oleksandr Boichuk, Oleksandra Marynchak, Viktoriia Kvasniuk, Andrii Protsyk, Ruslan Miziuk, Andrii Kucher, Marianna Simchych, Lilia Hryzhak, Mariia Kuravkin
Cardiovascular pathology can complicate the course of COVID-19. The study aimed to identify echocardiographic abnormalities and key prognostic factors influencing severe and fatal COVID-19 outcomes. This retrospective cohort study included clinical and echocardiogram data from 194 medical records of hospitalized patients with COVID-19: 100 moderate cases, 34 severe cases with favorable outcomes, and 60 severe cases with fatal outcomes. Severe patients with favorable outcomes had greater reductions in left ventricular systolic fraction of left ventricle compared to moderate cases (23...
November 2023: Journal of Medicine and Life
https://read.qxmd.com/read/38403566/hypertensive-emergency-secondary-to-atropine
#10
P R Carvalho, F Gonçalves, P Magalhães, J I Moreira
Atropine, a competitive antagonist of acetylcholine muscarinic receptors, is commonly used to treat severe bradycardia by blocking parasympathetic activity. We present a rare case of hypertensive emergency following atropine administration, with only one previous report in the literature. A 78-year-old woman with essential hypertension and hypercholesterolemia was admitted to the cardiac intensive care unit for non-ST segment elevation myocardial infarction. During coronary angiography, an occlusion of the right coronary artery was identified...
February 24, 2024: Hipertensión y Riesgo Vascular
https://read.qxmd.com/read/38385421/tacrolimus-associated-posterior-reversible-encephalopathy-syndrome-in-renal-transplant-recipient-in-early-posttransplant-period-case-report
#11
Syed Mohd Azhar Hassan
Posterior reversible encephalopathy syndrome is an emergency medical condition with varied causes presenting as reversible subcortical vasogenic brain edema caused by endothelial injury, resulting from changes in blood pressure or direct effects of cytokines on endothelium. Posterior reversible encephalopathy syndrome is manifested by neurologic symptoms. Common causes include hypertensive emergency, renal disease, preeclampsia, eclampsia, and immunosuppressive drugs. In this case report, a 17-year-old female patient on hemodialysis as a result of lupus nephritis who had previously undergone deceased donor organ transplant and was on triple immunosuppression presented with neurological symptoms of posterior reversible encephalopathy syndrome in the early posttransplant period...
January 2024: Experimental and Clinical Transplantation
https://read.qxmd.com/read/38384402/pregnancy-associated-atypical-hemolytic-uremic-syndrome-a-case-report-with-mcp-gene-mutation-and-successful-eculizumab-treatment
#12
Alex Domínguez-Vargas, Fanny Ariño, Diana Silva, Henry J González-Tórres, Gustavo Aroca-Martinez, Eduardo Egea, Carlos G Musso
Pregnancy-associated atypical hemolytic uremic syndrome (P-aHUS) is a rare condition characterized by microangiopathic hemolytic anemia and kidney injury from thrombotic microangiopathy. P-aHUS occurs in approximately 1 in 25,000 pregnancies and is strongly related to complement dysregulation and pregnancy-related disorders, such as preeclampsia, eclampsia, and hemolysis, elevated liver enzymes, low platelet (HELLP) syndrome, resulting in adverse perinatal and fetal outcomes. Complement dysregulation in P-aHUS is commonly attributed to genetic mutations or autoantibodies affecting complement factors, including CFH , CFI , and MCP...
January 2024: American Journal of Perinatology Reports
https://read.qxmd.com/read/38296661/neurological-hypertensive-emergencies-correlation-of-blood-pressure-values-with-in-hospital-outcomes-in-ischemic-stroke
#13
JOURNAL ARTICLE
Valentina Giani, Tommaso Valobra, Nicolò Capsoni, Michele Galasso, Lorenzo De Censi, Cecilia Ferretti, Andrea Sultana, Annalisa Giacalone, Ilaria Garofani, Michele Bombelli, Chiara Ceresa, Silvia Gheda, Elio Clemente Agostoni, Filippo Galbiati, Cristina Giannattasio, Alessandro Maloberti
BACKGROUND: Few certainties exist regarding optimal management of Blood Pressure (BP) in the very first hours after an ischemic stroke and many questions remain still unanswered. Our work aimed to evaluate the role of BP and its trend as possible determinants of in-hospital mortality (primary outcome), discharge disabilities and hospitalization length (secondary outcomes) in ischemic stroke patients presented with Hypertensive Emergencies (HE). METHODS: We retrospectively evaluated patients presented to Niguarda Hospital, Emergency Department (ED), from 2015 to 2017 with a neurological ischemic HE...
January 30, 2024: European Journal of Internal Medicine
https://read.qxmd.com/read/38261065/severe-labile-hypertension-in-a-patient-with-catecholamine-secreting-neuroblastoma-a-case-report
#14
JOURNAL ARTICLE
Jeanne Frisby-Zedan, Michael Migotsky, David O Walterhouse, Priya S Verghese
Neuroblastoma is a common pediatric tumor arising from the post-ganglionic sympathetic nervous system and is associated with hypertension in 25% of cases. We describe an unusual case of labile, multi-drug resistant hypertension associated with chemotherapy administration for neuroblastoma and provide potential management strategies in this scenario. We report the case of a 4-year-old female with a history of headaches who presented with hypertensive emergency and evidence of end-organ damage, including posterior reversible encephalopathy syndrome, acute cerebral infarct, concentric left ventricular hypertrophy, and growth failure secondary to a large, abdominal catecholamine-secreting neuroblastoma, which compressed the kidney vasculature and inferior vena cava...
January 23, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38240159/classification-algorithm-to-distinguish-between-type-1-and-type-2-myocardial-infarction-in-administrative-claims-data
#15
JOURNAL ARTICLE
Jason H Wasfy, Mary Price, Sharon-Lise T Normand, James L Januzzi, Cian P McCarthy, John Hsu
BACKGROUND: Type 2 myocardial infarction (T2MI) and type 1 myocardial infarction (T1MI) differ with respect to demographics, comorbidities, treatments, and clinical outcomes. Reliable quality and outcomes assessment depends on the ability to distinguish between T1MI and T2MI in administrative claims data. As such, we aimed to develop a classification algorithm to distinguish between T1MI and T2MI that could be applied to claims data. METHODS: Using data for beneficiaries in a Medicare accountable care organization contract in a large health care system in New England, we examined the distribution of MI diagnosis codes between 2018 to 2021 and the patterns of care and coding for beneficiaries with a hospital discharge diagnosis International Classification of Diseases , Tenth Revision code for T2MI, compared with those for T1MI...
January 19, 2024: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/38207103/unilateral-renal-artery-spasm-complicating-hypertensive-emergency-in-a-patient-with-secondary-aldosteronism
#16
JOURNAL ARTICLE
Hiroki Mori, Ryuji Okamoto, Shintaro Sakaguchi, Takafumi Koji, Kaoru Dohi
No abstract text is available yet for this article.
January 11, 2024: European Heart Journal Cardiovascular Imaging
https://read.qxmd.com/read/38205497/a-rare-case-of-primary-follicular-dendritic-cell-sarcoma-of-the-kidney
#17
Amanda E Sion, Josh Palka, Sarah Martin, Rafic Beydoun, Conrad Maitland
The objective of this case report is to describe a rare case of primary follicular dendritic cell sarcoma (FDCS) of the kidney. FDCS is a rare soft tissue malignancy that most often presents intranodally with lymphadenopathy of the neck, mediastinum, and axilla. One-third of cases present extranodally and most commonly affect the liver, lung, and tonsils. To date, there have been few reports of retroperitoneal FDCS and, to the best of our knowledge, only two other reported cases with primary renal involvement...
December 2023: Curēus
https://read.qxmd.com/read/38204853/characterizing-hypertension-specialist-care-in-canada-a-national-survey
#18
JOURNAL ARTICLE
Samantha Lui, Lisa Dubrofsky, Nadia A Khan, Sheldon W Tobe, Jessica Huynh, Laura Kuyper, Anna Mathew, Syed Amin, Ernesto L Schiffrin, Paula Harvey, Alexander A Leung, Marcel Ruzicka, Birinder Mangat, David Reid, John Floras, Jesse Bittman, Lauren Garbutt, Branko Braam, Rita Suri, Fady Hannah-Shmouni, Ally Prebtani, Sebastien Savard, Thomas E MacMillan, Terrence D Ruddy, Michel Vallee, Apoorva Bollu, Alexander Logan, Raj Padwal, Jennifer Ringrose
BACKGROUND: The hypertension specialist often receives referrals of patients with young-onset, severe, difficult-to-control hypertension, patients with hypertensive emergencies, and patients with secondary causes of hypertension. Specialist hypertension care compliments primary care for these complex patients and contributes to an overall hypertension control strategy. The objective of this study was to characterize hypertension centres and the practice patterns of Canadian hypertension specialists...
December 2023: CJC open
https://read.qxmd.com/read/38171869/effective-management-of-hypertensive-emergencies-with-aliskiren-treatment-in-a-patient-before-and-after-introducing-hemodialysis-secondary-to-scleroderma-renal-crisis-like-condition-under-corticosteroid-treatment-for-sj%C3%A3-gren-syndrome-associated-multiple-mononeuropathy
#19
JOURNAL ARTICLE
Osamu Yamazaki, Masataka Murakawa, Fumika Ochiai, Wataru Fujii, Shinichiro Asakawa, Michito Nagura, Shigeyuki Arai, Yoshifuru Tamura, Ryuji Ohashi, Shigeru Shibata, Yoshihide Fujigaki
A middle-aged woman presented with hypertensive emergency after corticosteroid treatment for Sjögren syndrome-associated multiple mononeuropathy with suspected systemic sclerosis. Hypertensive heart failure with hyperreninemia improved with antihypertensives, including aliskiren; however, she became hemodialysis-dependent. Clinical findings and biopsy-proven thrombotic microangiopathy indicated conditions resembling scleroderma renal crisis (SRC). Severe hypertension and heart failure with hyperreninemia occurred after stopping aliskiren for hypotension due to diverticular bleeding, which improved after the reintroduction of aliskiren...
January 2, 2024: Internal Medicine
https://read.qxmd.com/read/38111893/machine-learning-approaches-for-cardiovascular-hypertension-stage-estimation-using-photoplethysmography-and-clinical-features
#20
JOURNAL ARTICLE
Saad Abdullah, Annica Kristoffersson
Cardiovascular diseases (CVDs) are a leading cause of death worldwide, with hypertension emerging as a significant risk factor. Early detection and treatment of hypertension can significantly reduce the risk of developing CVDs and related complications. This work proposes a novel approach employing features extracted from the acceleration photoplethysmography (APG) waveform, alongside clinical parameters, to estimate different stages of hypertension. The current study used a publicly available dataset and a novel feature extraction algorithm to extract APG waveform features...
2023: Frontiers in Cardiovascular Medicine
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