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https://www.readbyqxmd.com/read/28806111/-effectiveness-of-mindfulness-based-cancer-recovery-mbcr-program-among-hungarian-cancer-patients
#1
Magda Rohánszky, Károly Berényi, Dóra Fridrik, Henriette Pusztafalvi
INTRODUCTION AND AIM: Employment of mindfulness-based programs and techniques in the treatment of cancer patients have spread exponentially in the past decade. A large number of studies have proved the effectiveness of the program in the reduction of stress symptoms, depression and anxiety, and the improvement of sleep and mood patterns. The present study was done at Firebird Foundation and examines the effectiveness of the complex, MBCR (mindfulness-based cancer recovery)-based psycho-social intervention in the treatment of cancer patients...
August 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28801952/positioning-telling-and-performing-a-male-illness-chronic-prostatitis-chronic-pelvic-pain-syndrome
#2
Nicholas Wood, Annum Qureshi, Fahim Mughal
OBJECTIVES: There is a paucity of illness accounts of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), despite a significant level of prevalence and burden of disease. This qualitative study thus elicited twelve accounts from men suffering with CP/CPPS. METHODS: Narrative analysis was employed, focusing primarily on narrative content. RESULTS: Three major narrative themes were identified: (1) Medical stories: Blame and shame; (2) The Erratic nature of CP/CPPS; and (3) Ongoing struggles for coping and cures and the Search for meaning...
August 11, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28801421/electroacupuncture-for-treating-insomnia-in-patients-with-cancer-a-study-protocol-for-a-randomised-pilot-clinical-trial
#3
Mikyung Kim, Jung-Eun Kim, Hye-Yoon Lee, Ae-Ran Kim, Hyo-Ju Park, O-Jin Kwon, Bo-Kyung Kim, Jung Hyo Cho, Joo-Hee Kim
INTRODUCTION: Although insomnia is one of the most prevalent and disturbing symptoms among patients with cancer, it has not been properly managed. Electroacupuncture (EA) has received attention as a promising intervention for insomnia, and a few previous studies have reported that this intervention may be beneficial for treating insomnia in patients with cancer. The aim of this pilot study is to explore the feasibility and preliminary effectiveness of EA on the sleep disturbance of patients with cancer with insomnia using a subjective method, patient-reported questionnaires and an objective tool, actigraphy, to measure the quality of sleep...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28797869/association-of-inflammatory-cytokines-with-the-symptom-cluster-of-pain-fatigue-depression-and-sleep-disturbance-in-chinese-patients-with-cancer
#4
Yan-Bo Ji, Chun-Lu Bo, Xiu-Juan Xue, En-Ming Weng, Guang-Chao Gao, Bei-Bei Dai, Kai-Wen Ding, Cui-Ping Xu
CONTEXT: Pain, fatigue, depression, and sleep disturbance are common in patients with cancer and usually co-occur as a symptom cluster. However, the mechanism underlying this symptom cluster is unclear. OBJECTIVES: This study aimed to identify subgroups of cluster symptoms, compare demographic and clinical characteristics between subgroups, and examine the associations between inflammatory cytokines and cluster symptoms. METHODS: Participants were 170 Chinese inpatients with cancer from two tertiary hospitals...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28791684/sleep-characteristics-light-at-night-and-breast-cancer-risk-in-a-prospective-cohort
#5
Alexandra J White, Clarice R Weinberg, Yong-Moon Park, Aimee A D'Aloisio, Emily Vogtmann, Hazel B Nichols, Dale P Sandler
Increasing numbers of women in the US are getting too little sleep. Inadequate sleep has been associated with impaired metabolic function and endocrine disruption. Sister Study cohort participants (n=50,884), completed baseline and follow-up questionnaires on sleep patterns. Incident breast cancers estrogen receptor (ER) status of the tumor were ascertained from questionnaires and medical records. Cox regression was used to estimate adjusted hazard ratios (HRs) and 95% confidence intervals (95% CIs). Analyses of sleep characteristics reported at the first follow-up interview included only participants who were breast cancer-free at time of follow-up interview...
August 9, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28781755/what-do-hypnotics-cost-hospitals-and-healthcare
#6
Daniel F Kripke
Hypnotics (sleeping pills) are prescribed widely, but the economic costs of the harm they have caused have been largely unrecognized. Randomized clinical trials have proven that hypnotics increase the incidence of infections. Likewise, hypnotics increase the incidence of major depression and cause emergency admissions for overdoses and deaths.  Epidemiologically, hypnotic use is associated with cancer, falls, automobile accidents, and markedly increased overall mortality.  This article considers the costs to hospitals and healthcare payers of hypnotic-induced infections and other severe consequences of hypnotic use...
2017: F1000Research
https://www.readbyqxmd.com/read/28770976/non-steroidal-anti-inflammatory-drugs-nsaids-for-chronic-non-cancer-pain-in-children-and-adolescents
#7
REVIEW
Christopher Eccleston, Tess E Cooper, Emma Fisher, Brian Anderson, Nick Mr Wilkinson
BACKGROUND: Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in children is a major public health concern of high significance in most parts of the world. While in the past pain was largely dismissed and was frequently left untreated, views on children's pain have changed over time, and relief of pain is now seen as important...
August 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28767095/the-combined-effects-of-aircraft-and-road-traffic-noise-and-aircraft-and-railway-noise-on-noise-annoyance-an-analysis-in-the-context-of-the-joint-research-initiative-norah
#8
Jördis Wothge, Christin Belke, Ulrich Möhler, Rainer Guski, Dirk Schreckenberg
The Noise Related Annoyance Cognition and Health (NORAH) research initiative is one of the most extensive studies on the physiological and psychological long-term effects of transportation noise in Europe. It includes research on the quality of life and annoyance as well as cardiovascular effects, sleep disturbance, breast cancer, blood pressure, depression and the cognitive development of children. Within the realm of the annoyance module of the study approximately 10,000 residents of the Rhine-Main district were surveyed on the combined effects of transportation noise...
August 2, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28748522/mindfulness-based-interventions-and-sleep-among-cancer-survivors-a-critical-analysis-of-randomized-controlled-trials
#9
REVIEW
Georgia Christodoulou, David S Black
PURPOSE OF REVIEW: The purpose of our critical examination is to present results and provide a synthesis of this body of work. RECENT FINDINGS: Sleep problems among cancer survivors are gaining research attention. To our knowledge, there have been six randomized control trials published from 2013 to 2015 that test the effects of mindfulness-based interventions (MBIs) on sleep as a primary or secondary outcome. Our examination of the literature highlights important methodological issues and variability among trials...
September 2017: Current Oncology Reports
https://www.readbyqxmd.com/read/28739368/andrographolide-induces-oxidative-stress-dependent-cell-death-in-unicellular-protozoan-parasite-trypanosoma-brucei
#10
Malabika Banerjee, Debaprasad Parai, Pranab Dhar, Manab Roy, Rajib Barik, Subrata Chattopadhyay, Samir Kumar Mukherjee
African sleeping sickness is a parasitic disease in humans and livestock caused by Trypanosoma brucei throughout sub-Saharan Africa. Absence of appropriate vaccines and prevalence of drug resistance proclaim that a new way of therapeutic interventions is essential against African trypanosomiasis. In the present study, we have looked into the effect of andrographolide (andro), a diterpenoid lactone from Andrographis paiculata on Trypanosoma brucei PRA 380. Although andro has been recognized as a promosing anti-cancer drug, its usefulness against Trypanosoma spp remained unexplored...
July 21, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28738963/-somatization-symptoms-in-lung-cancer-patients-and-correlative-analysis-between-anxiety-depression-and-somatization-symptoms
#11
Xinyao Zhang, Xiaoye Zhang
BACKGROUND: Lung cancer is a serious threat to human health and its morbidity and mortality in recent years has always been ranked first in the country. Lung cancer patients are often associated with anxiety, depression and other emotional problems, and anxiety, depression and other emotional problems will further lead to a series of somatic symptoms. At present, we lack the clinical understanding of somatization symptoms in patients with lung cancer and related clinical studies are not too much...
July 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28736816/antinociceptive-activity-of-ent-dihydrotucumanoic-acid-isolated-from-gymnosperma-glutinosum-spreng-less
#12
Angel Josabad Alonso-Castro, Marco Martin González-Chávez, Juan Ramón Zapata-Morales, Alexia Karina Verdinez-Portales, Amanda Sánchez-Recillas, Rolffy Ortiz-Andrade, Mario Isiordia-Espinoza, Fidel Martínez-Gutiérrez, Marco Antonio Ramírez-Morales, Fabiola Domínguez, María Elizabeth Juache-Flores, Roberto Martínez
Preclinical Research The diterpene ent-dihydrotumanoic acid (DTA) was among the compounds isolated from Gymnosperma glutinosum (Spreng) Less (Asteraceae). There are no reports regarding the pharmacological effects of DTA. Cytotoxicity against cancer cells (1-250 µM), and the antibacterial (50-1400 µM) activity of DTA were evaluated using the MTT assay, and the minimum inhibitory concentration test, respectively. The antidiarrheal (1-100 mg/kg p.o.) and anti-inflammatory (2 mg/ear) effects of DTA were evaluated using castor oil and 12-O-tetradecanoylphorbol-13-acetate, respectively...
July 24, 2017: Drug Development Research
https://www.readbyqxmd.com/read/28735919/sleep-disturbances-at-the-time-of-a-new-diagnosis-a-comparative-study-of-human-immunodeficiency-virus-patients-cancer-patients-and-general-population-controls
#13
Yen-Chin Chen, Cheng-Yu Lin, Carol Strong, Chung-Yi Li, Jeen-Shing Wang, Wen-Chien Ko, Nai-Ying Ko
OBJECTIVES: Sleep disturbances are a prevalent and troubling symptom of patients with highly stressful illnesses, such as human immunodeficiency virus (HIV) and cancer. The aim of this study was to compare the prevalence and incidence of sleep disturbances among persons with HIV, those with cancer, and the general population of Taiwan. METHODS: A matched cohort study design was used to compare the risk of sleep disturbances among three groups using reimbursement claims recorded in Taiwan's National Health Insurance Research Database (NHIRD)...
August 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28725169/postoperative-delirium-after-pharyngolaryngectomy-with-esophagectomy-a-role-for-ramelteon-and-suvorexant
#14
Eisuke Booka, Yasuhiro Tsubosa, Teruaki Matsumoto, Mari Takeuchi, Takashi Kitani, Masato Nagaoka, Atsushi Imai, Tomoyuki Kamijo, Yoshiyuki Iida, Ayako Shimada, Katsushi Takebayashi, Masahiro Niihara, Keita Mori, Tetsuro Onitsuka, Hiroya Takeuchi, Yuko Kitagawa
BACKGROUND: Postoperative delirium is common after extensive surgery, and is known to be associated with sleeping medications. In this study, we aimed to investigate the relationships between sleeping medications and postoperative delirium after pharyngolaryngectomy with esophagectomy. METHODS: We performed a retrospective analysis of 65 patients who underwent pharyngolaryngectomy with esophagectomy at Shizuoka Cancer Center Hospital between January 2012 and March 2016...
2017: Esophagus: Official Journal of the Japan Esophageal Society
https://www.readbyqxmd.com/read/28724549/identification-of-new-tumor-suppressor-genes-in-triple-negative-breast-cancer
#15
Roberto Rangel, Liliana Guzman-Rojas, Takahiro Kodama, Michiko Kodama, Justin Y Newberg, Neal G Copeland, Nancy A Jenkins
Although genomic sequencing has provided a better understating of the genetic landmarks in triple-negative breast cancer (TNBC), functional validation of candidate cancer genes (CCG) remains unsolved. In this study, we used a transposon mutagenesis strategy based on a two-step Sleeping Beauty (SB) forward genetic screen to identify and validate new tumor suppressors (TS) in this disease. We generated 120 siRNAs targeting 40 SB-identified candidate breast cancer TS genes and used them to downregulate expression of these genes in four human TNBC cell lines...
July 19, 2017: Cancer Research
https://www.readbyqxmd.com/read/28721811/moving-to-the-rhythm-with-clock-circadian-genes-autophagy-mtor-and-sirt1-in-degenerative-disease-and-cancer
#16
Kenneth Maiese
BACKGROUND: The mammalian circadian clock and its associated clock genes are increasingly be recognized as critical components for a number of physiological and disease processes that extend beyond hormone release, thermal regulation, and sleep-wake cycles. New evidence suggests that clinical behavior disruptions that involve prolonged shift work and even space travel may negatively impact circadian rhythm and lead to multi-system disease. METHODS: In light of the significant role circadian rhythm can hold over the body's normal physiology as well as disease processes, we examined and discussed the impact circadian rhythm and clock genes hold over lifespan, neurodegenerative disorders, and tumorigenesis...
July 17, 2017: Current Neurovascular Research
https://www.readbyqxmd.com/read/28720269/relationships-of-salivary-cortisol-and-melatonin-rhythms-to-sleep-quality-emotion-and-fatigue-levels-in-patients-with-newly-diagnosed-lung-cancer
#17
Wen-Pei Chang, Chia-Chin Lin
PURPOSE: After being diagnosed with lung cancer, patients often experience sleep disturbance, anxiety, depression, and fatigue. These symptoms may occur because of changes in neurotransmitter secretion caused by tumors. This study investigated the correlation of cortisol and melatonin rhythms with sleep quality, anxiety, depression, and fatigue levels in patients with newly diagnosed lung cancer. METHOD: We conducted a case-control study and recruited 40 patients with newly diagnosed lung cancer and 40 healthy adults...
August 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28720264/fatigue-and-health-related-quality-of-life-in-children-and-adolescents-with-cancer
#18
Michelle Darezzo Rodrigues Nunes, Eufemia Jacob, Emiliana Omena Bomfim, Luis Carlos Lopes-Junior, Regina Aparecida Garcia de Lima, Milena Floria-Santos, Lucila Castanheira Nascimento
PURPOSE: The study examined the different dimensions of fatigue (general, sleep/rest, cognitive), health related quality of life (HRQL) (physical, emotional, cognitive, social), and the relationships between fatigue and HRQL in hospitalized children and adolescents with cancer in Brazil. METHOD: Participants were recruited from a pediatric oncology inpatient unit in a comprehensive cancer care hospital in southeast Brazil. They completed the PedsQL Multidimensional Fatigue Scale and the PedsQL Inventory of Quality of Life (Generic and Cancer module) once during hospitalization...
August 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28710110/impact-of-a-patient-tailored-complementary-integrative-medicine-programme-on-disturbed-sleep-quality-among-patients-undergoing-chemotherapy
#19
Hilit Kerner, Noah Samuels, Shlomi Ben Moshe, Ilanit Shalom Sharabi, Eran Ben-Arye
OBJECTIVES: The present study examined the impact of a patient-tailored complementary/integrative medicine (CIM) programme on sleep quality in patients undergoing chemotherapy for breast and gynaecological cancer. METHODS: Study participants received standard supportive care, with or without weekly CIM treatments. Disturbed sleep quality was defined as a score of ≥4 on the Edmonton Symptom Assessment Scale (ESAS) or a score of ≥3 on the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30)...
July 14, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28707741/randomized-clinical-trial-of-psychological-support-and-sleep-adjuvant-measures-for-postoperative-sleep-disturbance-in-patients-undergoing-oesophagectomy
#20
M Scarpa, E Pinto, E Saraceni, F Cavallin, M Parotto, R Alfieri, M T Nardi, M R Marchi, M Cagol, C Castoro
BACKGROUND: Major surgery such as oesophagectomy requires a postoperative stay in intensive care. Painful stimuli lead to sleep disturbance and impairment in quality of life. The aim of this study was to evaluate the effect of psychological counselling and sleep adjuvant measures on postoperative quality of sleep and quality of life. METHODS: This RCT was performed between January 2013 and October 2015. Patients undergoing oesophagectomy for cancer were randomized into one of four groups receiving: psychological counselling plus sleep adjuvant measures during the ICU stay; psychological counselling alone; sleep adjuvant measures alone during the ICU stay; or standard care...
September 2017: British Journal of Surgery
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