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https://www.readbyqxmd.com/read/30106932/pure-three-level-yb-gdcob-cw-laser-at-976-nm
#1
Jing Xia, Huilong Liu, Zonghua Hu, Rui Yang, Jun Zhang, Zejun Jiang, Yanfei Lü
We present what is, to the best of our knowledge, the first pure-three-level Yb:Ca4 GdO(BO3 )3 (Yb:GdCOB) laser emitting at 976 nm based on the F5/2 2-F27/2 transition, generally used for a quasi-three-level emission at 1032 nm. A maximum power of 782 mW at 976 nm has been achieved in continuous-wave (CW) operation pumped by a quasi-three-level Nd:SrLaAlO4 laser emitting at 902 nm. Moreover, a self-frequency-doubling CW blue laser has also been demonstrated with a maximum power of 133 mW at 488 nm.
August 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/30102046/rhodium-catalyzed-formylation-of-aryl-halides-with-co-2-and-h-2
#2
Zhenghui Liu, Zhenzhen Yang, Bo Yu, Xiaoxiao Yu, Hongye Zhang, Yanfei Zhao, Peng Yang, Zhimin Liu
The reductive formylation of aryl iodides/bromides to aryl aldehydes using CO2 /H2 is presented for the first time. It was realized over a catalytic system composed of RhI3 or RhI3 /Pd(dppp)Cl2 (dppp = 1,3-bis(diphenyphosphino)propane) and PPh3 in the presence of Ac2 O/Et3 N at 100 °C, affording aromatic aldehydes in good to excellent yields, together with good functional-group tolerance and broad substrate scope. The reaction proceeds through three cascade steps, involving HCOOH formation, CO release, and formylation of aryl halides...
August 13, 2018: Organic Letters
https://www.readbyqxmd.com/read/30095903/aaron-an-automated-reaction-optimizer-for-new-catalysts
#3
Yanfei Guan, Victoria M Ingman, Benjamin J Rooks, Steven E Wheeler
We describe an open-source computational toolkit (AARON: An Automated Reaction Optimizer for New catalysts) that automates the quantum mechanical geometry optimization and characterization of the transition state and intermediate structures required to predict the activities and selectivities of asymmetric catalytic reactions. Modern computational quantum chemistry has emerged as a powerful tool for explaining the selectivity and activity of asymmetric catalysts. However, reliably predicting the stereochemical outcome of realistic reactions often requires the geometry optimization of hundreds of transition state and intermediate structures, which is a tedious process...
August 10, 2018: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/30082160/diagnostic-value-of-rassf1a-hypermethylation-in-colorectal-cancer-a-meta-analysis
#4
Haochang Hu, Cong Zhou, Bin Li, Yanfei Chen, Jie Dai, Yiyi Mao, Tianyi Huang, Hang Yu, Min Chen, Jun Zhao, Shiwei Duan
PURPOSE: Ras association domain family 1 isoform A (RASSF1A), a member of Ras association domain family, plays an important role in tumorigenesis. The goal of our meta-analysis was to assess the diagnostic value of RASSF1A hypermethylation in colorectal cancer (CRC). METHODS: PubMed, Embase, CNKI and Wanfang databases were used to conduct literature selection. The association between RASSF1A methylation and CRC risk was evaluated by odds ratios (ORs) and 95% confidence intervals (CIs)...
July 27, 2018: Pathology, Research and Practice
https://www.readbyqxmd.com/read/30081927/pca-and-deep-learning-based-myoelectric-grasping-control-of-a-prosthetic-hand
#5
Chuanjiang Li, Jian Ren, Huaiqi Huang, Bin Wang, Yanfei Zhu, Huosheng Hu
BACKGROUND: For the functional control of prosthetic hand, it is insufficient to obtain only the motion pattern information. As far as practicality is concerned, the control of the prosthetic hand force is indispensable. The application value of prosthetic hand will be greatly improved if the stable grip of prosthetic hand can be achieved. To address this problem, in this study, a bio-signal control method for grasping control of a prosthetic hand is proposed to improve patient's sense of using prosthetic hand and the thus improving the quality of life...
August 6, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/30079259/a-convenient-and-sensitive-lc-ms-ms-method-for-simultaneous-determination-of-carbadox-and-olaquindox-related-residues-in-swine-muscle-and-liver-tissues
#6
Heying Zhang, Wei Qu, Yanfei Tao, Dongmei Chen, Shuyu Xie, Lingli Huang, Zhenli Liu, Yuanhu Pan, Zonghui Yuan
This paper presents a convenient and sensitive LC-MS/MS method for the simultaneous determination of carbadox and olaquindox residues, including desoxyolaquindox (DOLQ), desoxycarbadox (DCBX), quinoxaline-2-carboxylic acid (QCA), 3-methyl-quinoxaline-2-carboxylic acid (MQCA), and the glycine conjugates of QCA and MQCA (namely, QCA-glycine and MQCA-glycine, resp.) in swine muscle and liver tissues. Tissue samples were extracted with 2% metaphosphoric acid in 20% methanol and cleaned up by solid-phase extraction (SPE) on a mixed-mode anion-exchange column (Oasis MAX)...
2018: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/30078190/establishment-and-characterization-of-a-telomerase-immortalized-porcine-bronchial-epithelial-cell-line
#7
Xing Xie, Yuan Gan, Maoda Pang, Guoqing Shao, Lei Zhang, Beibei Liu, Qi Xu, Haiyan Wang, Yanyan Feng, Yanfei Yu, Rong Chen, Meng Wu, Zhenzhen Zhang, Lizhong Hua, Qiyan Xiong, Maojun Liu, Zhixin Feng
Primary porcine bronchial epithelial cells (PBECs) are an ideal model to study the molecular and pathogenic mechanisms of various porcine respiratory pathogens. However, the short lifespan of primary PBECs greatly limit their application. Here, we isolated and cultured primary PBECs and established immortalized PBECs by transfecting primary PBECs with the pEGFP-hTERT recombinant plasmid containing human telomerase reverse transcriptase (hTERT). Immortalized PBECs (hTERT-PBECs) retained the morphological and functional features of primary PBECs as indicated by cytokeratin 18 expression, telomerase activity assay, proliferation assays, karyotype analysis, and quantitative reverse-transcriptase polymerase chain reaction...
August 5, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/30073893/novel-otof-gene-mutations-identified-using-a-massively-parallel-dna-sequencing-technique-in-dfnb9-deafness
#8
Yanfei Wang, Yu Lu, Jing Cheng, Lei Zhang, Dongyi Han, Huijun Yuan
OBJECTIVES: This study examined the causative genes in patients with early-onset hearing loss from two Chinese families. METHOD: Massively parallel sequencing, designed to screen all reported genes associated with hearing loss, was performed in a large number of Chinese individuals with hearing loss. This study enrolled patients with the same OTOF mutation and analyzed their phenotype-genotype correlations. RESULTS: Three novel OTOF mutations (NM_001287489) [c...
August 3, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/30067809/regulation-of-protein-coding-gene-and-long-noncoding-rna-pairs-in-liver-of-conventional-and-germ-free-mice-following-oral-pbde-exposure
#9
Cindy Yanfei Li, Julia Yue Cui
Gut microbiome communicates with the host liver to modify hepatic xenobiotic biotransformation and nutrient homeostasis. Polybrominated diphenyl ethers (PBDEs) are persistent environmental contaminants that are detected in fatty food, household dust, and human breast milk at worrisome levels. Recently, long noncoding RNAs (lncRNAs) have been recognized as novel biomarkers for toxicological responses and may regulate the transcriptional/translational output of protein-coding genes (PCGs). However, very little is known regarding to what extent the interactions between PBDEs and gut microbiome modulate hepatic lncRNAs and PCGs, and what critical signaling pathways are impacted at the transcriptomic scale...
2018: PloS One
https://www.readbyqxmd.com/read/30067799/risk-factors-for-extremely-serious-road-accidents-results-from-national-road-accident-statistical-annual-report-of-china
#10
Guodong Liu, Siyu Chen, Ziqian Zeng, Huijie Cui, Yanfei Fang, Dongqing Gu, Zhiyong Yin, Zhengguo Wang
BACKGROUND: In the past decades, extremely serious road accidents with a death toll over ten in each have become a severe public health problem in China. This study investigates risk factors contributing to extremely serious road accidents, which will be crucial for accident prevention. METHODS: Collecting data from The Road Accident Statistical Annual Report openly issued by China's Traffic Management Bureau of the Public Security Ministry for the time period 2004-2015, we used the monthly case number of extreme serious road accidents as the dependent variable...
2018: PloS One
https://www.readbyqxmd.com/read/30061618/monitoring-and-detection-of-leprosy-patients-in-southwest-china-a-retrospective-study-2010-2014
#11
Wang Le, Jiang Haiqin, Hao Danfeng, Shi Ying, Zhang Wenyue, Yang Jun, Xiong Li, Shui Tiejun, Shen Limei, Liu Jie, Wang De, Ning Yong, Liu Yangying, Wang Hao, Kuang Yanfei, Li Bin, Yumi Maeda, Malcolm Duthie, Yu Meiwen, Wang Hongsheng, Yan Liangbin, Zhang Guocheng, Wang Baoxi, Gu Heng
More than 100 counties, mainly in southwest China, report incidence rates of leprosy >1/100,000. The current study analysed the epidemiology of leprosy in southwest China to improve our understanding of the transmission pattern and improve control programs. 207 counties were selected in southwest China. Leprosy patients and their household contacts were recruited. The data from the medical interview and the serological antileprosy antibody of the leprosy patients were analysed. A total of 2,353 new cases of leprosy were interviewed...
July 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30060539/qos-driven-adaptive-trust-service-coordination-in-the-industrial-internet-of-things
#12
Jin Qi, Zian Wang, Bin Xu, Mengfei Wu, Zian Gao, Yanfei Sun
The adaptive coordination of trust services can provide highly dependable and personalized solutions for industrial requirements in the service-oriented industrial internet of things (IIoT) architecture to achieve efficient utilization of service resources. Although great progress has been made, trust service coordination still faces challenging problems such as trustless industry service, poor coordination, and quality of service (QoS) personalized demand. In this paper, we propose a QoS-driven and adaptive trust service coordination method to implement Pareto-efficient allocation of limited industrial service resources in the background of the IIoT...
July 27, 2018: Sensors
https://www.readbyqxmd.com/read/30060427/production-of-lactic-acid-from-thermal-pretreated-food-waste-through-the-fermentation-of-waste-activated-sludge-effects-of-substrate-and-thermal-pretreatment-temperature
#13
Jun Li, Wenjuan Zhang, Xiang Li, Tingting Ye, Yanfei Gan, Ai Zhang, Hong Chen, Gang Xue, Yanan Liu
Valorization of organic-rich waste stream to lactic acid by the mixed microbial consortium has attracted tremendous research interests in recent years. In this study, thermal pretreatment was involved in co-fermentation of food waste (FW) and waste activated sludge (WAS) to enhance lactic acid production. First, sole FW was observed as the most suitable substrate employing thermal pretreatment for the generation of lactic acid. The fermentation time for reaching the maximal plateau was significantly shortened at a corresponding thermal pretreatment temperature...
January 2018: Bioresource Technology
https://www.readbyqxmd.com/read/30055385/biodegradation-of-phenanthrene-by-biodemulsifier-producing-strain-achromobacter-sp-lh-1-and-the-study-on-its-metabolisms-and-fermentation-kinetics
#14
Ning Hou, Nannan Zhang, Tingting Jia, Yang Sun, Yanfei Dai, Qiquan Wang, Dapeng Li, Zhengkai Luo, Chunyan Li
Despite many reports of the use of biodegradation to remove contaminants, the biodegradation of polycyclic aromatic hydrocarbons (PAHs) is challenging because of the hydrophobicities and low aqueous solubilities of most PAHs. In this study, phenanthrene (PHE) was used as a sole carbon and energy source to screen and identify Achromobacter sp. LH-1 for the production of biodemulsifiers that enhance the bioavailability and solubilization of PAHs. LH-1 achieved a 94% degradation rate and a 40% mineralization rate with 100 mg/L PHE...
July 25, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/30051521/effect-of-sex-differences-in-donor-foetal-fibroblast-on-the-early-development-and-dna-methylation-status-of-buffalo-bubalus-bubalis-nuclear-transfer-embryos
#15
Ziyun Ruan, Xin Zhao, Zhengda Li, Xiling Qin, Qiming Shao, Qiuyan Ruan, Yanfei Deng, Jianrong Jiang, Ben Huang, Fenghua Lu, Deshun Shi
Low efficiency of somatic cell nuclear transfer (SCNT) embryos is largely attributable to imperfect reprogramming of the donor nucleus. The differences in epigenetic reprogramming between female and male buffalo cloned embryos remain unclear. We explored the effects of donor cell sex differences on the development of SCNT embryos. We and then compared the expression of DNA methylation (5-methylcytosine-5mC and 5-hydroxymethylcytosine-5hmC) and the expression level of relevant genes, and histone methylation (H3K9me2 and H3K9me3) level in SCNT-♀ and SCNT-♂ preimplantation embryos with in vitro fertilization (IVF) counterparts...
July 27, 2018: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/30045018/mir-135a-protects-vascular-endothelial-cells-against-ventilator-induced-lung-injury-by-inhibiting-phlpp2-to-activate-pi3k-akt-pathway
#16
Xiaodi Yan, Wenqian Li, Liye Yang, Wenwen Dong, Wei Chen, Yanfei Mao, Pingbo Xu, Dongjie Li, Hongbin Yuan, Yong-Hua Li
BACKGROUND/AIMS: Loss of endothelial barrier function plays an important role in the development of ventilator-induced lung injury (VILI). This study aimed to investigate the effects of miR135a on VILI in a model of mechanical stretch (MS)-induced human umbilical vein endothelial cell (HUVEC) injury. METHODS: HUVECs were randomly assigned to 7 groups: blank, negative control (NC), NC+MS, miR135a over-expression (mi-miR135a), mi-miR135a + MS, miR135a silencing (si-miR135a) and si-miR135a + MS groups...
July 25, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/30041125/polarized-infrared-spectroscopy-imaging-applied-to-structural-analysis-of-bilirubin-aggregate-at-liquid-liquid-interface
#17
Yanfei Lu, Mingyang Zhai, Yongkang Zhu, Xiao Wang, Jianhua Yin
Fourier transform infrared spectroscopy imaging (FTIRSI) combined with spectral analysis and polarization approach was creatively used to investigate both structures of bilirubin (BR) precipitate and BR aggregate at liquid-liquid interface. It was found by spectral analysis that the internal hydrogen bonds of BR molecules all broke and the dihedral angles increased during the formation of BR aggregate at liquid-liquid interface. And the BR molecule might be of layer assembly along the long axis direction of CD half-group to form J-type aggregates, which could be parallel to the direction of the transition dipole moment of BR aggregate...
July 17, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/30032906/intratympanic-injection-of-dexamethasone-after-failure-of-intravenous-prednisolone-in-simultaneous-bilateral-sudden-sensorineural-hearing-loss
#18
Bo Tang, Yanfei Jia, Zhe Shi, Yunjuan Shen, Denghui Li, Hailong Huang, Baohui Yang, Daowen Wang, Qian Feng
PURPOSE: This study aimed to analyze outcomes of intratympanic injection of dexamethasone after failure of intravenous prednisolone in simultaneous bilateral sudden sensorineural hearing loss (SSNHL). MATERIALS AND METHODS: The cases of simultaneous bilateral SSNHL treated in our hospital from March 2007 to March 2018 were retrospectively analyzed. During the earlier period (March 2007 to February 2012), the cases were treated by intravenous prednisolone only, and classified into group A...
July 12, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30029384/polyoxometalates-as-promising-enzyme-mimics-for-the-sensitive-detection-of-hydrogen-peroxide-by-fluorometric-method
#19
Rui Tian, Boyu Zhang, Mingming Zhao, Qiang Ma, Yanfei Qi
Polyoxometalates (POMs) have been proven to possess intrinsic peroxidase-like activity. However, by far, most of POMs with intrinsic peroxidase-like activity are stable at acid aqueous. Herein, we firstly utilized Na10 [α-SiW9 O34 ] with the peroxidase-like property in basic pH condition to build a CdTe quantum dots (QDs)-based fluorometric method for detection of hydrogen peroxide. In the CdTe QDs stable pH value, Na10 [α-SiW9 O34 ] can catalyze the decomposition of H2 O2 into·OH radicals that could efficiently quench the fluorescence of CdTe QDs...
October 1, 2018: Talanta
https://www.readbyqxmd.com/read/30021063/stretchable-implantable-nanostructured-flow-diverter-system-for-quantification-of-intra-aneurysmal-hemodynamics
#20
Connor Howe, Saswat Mishra, Yun-Soung Kim, Yanfei Chen, Sang-Ho Ye, William R Wagner, Jae-Woong Jeong, Hun-Soo Byun, Jong-Hoon Kim, Youngjae Chun, Woon-Hong Yeo
Random weakening of an intracranial blood vessel results in abnormal blood flow into an aneurysmal sac. Recent advancements show that an implantable flow diverter, integrated with a medical stent, enables a highly effective treatment of cerebral aneurysms by guiding blood flow into the normal vessel path. None of such treatment systems, however, offers post-treatment monitoring to assess the progress of sac occlusion. Therefore, physicians rely heavily on either angiography or magnetic resonance imaging. Both methods require a dedicated facility with sophisticated equipment settings and time-consuming, cumbersome procedures...
July 20, 2018: ACS Nano
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