Youwen Ma, Mingwei Gu, Liguo Chen, Hao Shen, Yifan Pan, Yan Pang, Sheng Miao, Ruiqing Tong, Haibo Huang, Yichen Zhu, Lining Sun
The normal development and maturation of oocytes and sperm, the formation of fertilized ova, the implantation of early embryos, and the growth and development of foetuses are the biological basis of mammalian reproduction. Therefore, research on oocytes has always occupied a very important position in the life sciences and reproductive medicine fields. Various embryo engineering technologies for oocytes, early embryo formation and subsequent developmental stages and different target sites, such as gene editing, intracytoplasmic sperm injection (ICSI), preimplantation genetic diagnosis (PGD), and somatic cell nuclear transfer (SCNT) technologies, have all been established and widely used in industrialization...
2021: Theranostics