keyword
https://read.qxmd.com/read/38575260/spontaneous-intracranial-hypotension-clinical-presentation-diagnosis-and-treatment-strategies
#21
REVIEW
Jr-Wei Wu, Shuu-Jiun Wang
Spontaneous intracranial hypotension (SIH) typically presents as an acute orthostatic headache during an upright position, secondary to spinal cerebrospinal fluid leaks. New evidence indicates that a lumbar puncture may not be essential for diagnosing every patient with SIH. Spinal neuroimaging protocols used for diagnosing and localizing spinal cerebrospinal fluid leaks include brain/spinal MRI, computed tomography myelography, digital subtraction myelography, and radionuclide cisternography. Complications of SIH include subdural hematoma, cerebral venous thrombosis, and superficial siderosis...
May 2024: Neurologic Clinics
https://read.qxmd.com/read/38568245/investigating-bleeding-adverse-events-associated-with-btk-inhibitors-in-the-food-and-drug-administration-adverse-event-reporting-system-faers
#22
JOURNAL ARTICLE
Xianlin Li, Nan Shang, Qianci Yan, Xiunan Yue, Yang Liu, Xiaojun Zheng
BACKGROUND: This study analyzed the bleeding adverse events (AEs) resulting from the treatment of B-cell lymphoma with Bruton tyrosine kinase (BTK) inhibitors, according to reports in the US Food and Drug Administration's Adverse Event Reporting System (FAERS). METHODS: Bleeding AEs associated with BTK inhibitors (including ibrutinib, zanubrutinib, and acalabrutinib) from the first quarter of 2013 to the third quarter of 2023 were extracted. Reporting odds ratio (ROR) and proportional reporting ratio (PRR) were reported...
April 3, 2024: Expert Opinion on Drug Safety
https://read.qxmd.com/read/38558741/cerebral-vasospasm-after-burr-hole-evacuation-of-chronic-subdural-hematoma
#23
Masahiro Morishita, Takaaki Yamazaki, Makoto Senoo, Mikio Nishiya
Cerebral vasospasm is a frequent complication of subarachnoid hemorrhage. We report a case of chronic subdural hematoma complicated by cerebral vasospasm after burr hole evacuation. A 74-year-old woman underwent burr hole evacuation of a chronic subdural hematoma. She developed left hemiparesis and disturbance of consciousness on postoperative day 3. Magnetic resonance imaging showed a right parietal infarct and decreased cerebral blood flow signal in the right middle cerebral artery territory. Digital subtraction angiography showed multiple segmental narrowings of the right middle cerebral artery...
February 2024: Curēus
https://read.qxmd.com/read/38554980/single-cell-sequencing-analysis-of-chronic-subdural-hematoma-cell-subpopulations-and-their-potential-therapeutic-mechanisms
#24
JOURNAL ARTICLE
Qian Zhang, Rundong Chen, Lufeng Shi, Hehe Zhao, Fei Yin, Cong Yu, Yirong Wang, Peng Lu
BACKGROUND: Chronic subdural hematoma (CSDH) is a prevalent form of intracranial haemorrhage encountered in neurosurgical practice, and its incidence has notably risen in recent years. Currently, there is a lack of studies that have comprehensively classified the cells present in hematomas removed during surgery, and their correlation with CSDH recurrence remains elusive. This study aims to analyse the subcellular populations and occupancy levels within peripheral blood. METHODS: This study analyses the subcellular populations and occupancy levels within peripheral blood and postoperatively removed hematomas by single-cell sequencing and attempts to analyse the effect of different cell occupancies within peripheral blood and intraoperatively removed hematomas on CSDH...
March 28, 2024: Brain Research Bulletin
https://read.qxmd.com/read/38554149/factors-associated-with-success-of-conservative-therapy-in-chronic-subdural-hematoma-a-single-center-retrospective-analysis
#25
JOURNAL ARTICLE
Merijn Foppen, Roger Lodewijkx, Harssh Verdan Bandral, Kevin Yah, K Mariam Slot, William Vandertop, Dagmar Verbaan
INTRODUCTION: Conservative therapy is a viable option for patients with chronic subdural hematoma (cSDH) who express no, or only mild symptoms. It is not clear which factors are associated with success of conservative therapy. This study aims to determine conservative therapy's success rate and to identify features possibly associated with success. METHODS: A monocenter retrospective cohort study, including cSDH patients treated conservatively (wait-and-watch) from 2012 to 2022, was performed...
March 30, 2024: Journal of Neurology
https://read.qxmd.com/read/38552637/the-extension-of-traumatic-subdural-hematoma-into-the-interhemispheric-fissure-is-associated-with-coagulation-disorders-a-retrospective-study
#26
JOURNAL ARTICLE
Lennart W Sannwald, Dag Moskopp, Mats L Moskopp
BACKGROUND:  This study investigates the correlation of the radiologic sign of interhemispheric subdural hematoma (iSDH) in different injury patterns with clinical coagulation disorders. It is hypothesized that the presence of iSDHs is correlated with clinical coagulation disorders in patients with traumatic brain injuries and subdural hematoma (SDH). METHODS:  Between January 1, 2020 and June 30, 2022, 154 patients with SDH were identified. Coagulation disorders were assessed using chart review and patients were divided into four groups: SDH without iSDH without further injuries (SDH), SDH with iSDH without further injuries (SDH + iSDH), SDH without iSDH with further brain injuries (Combi), SDH with iSDH with further injuries (Combi + iSDH)...
March 29, 2024: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://read.qxmd.com/read/38552232/epidemiology-of-moderate-traumatic-brain-injury-and-factors-associated-with-poor-neurological-outcome
#27
JOURNAL ARTICLE
Shu Utsumi, Shingo Ohki, Nobuaki Shime
OBJECTIVE: The objective of this study was to investigate the epidemiology of moderate traumatic brain injury (TBI) and factors associated with poor neurological outcome. METHODS: This multicenter retrospective cohort study used data from the Japan Trauma Data Bank from 2019 to 2022, including adult patients (aged > 17 years) with moderate TBI (Glasgow Coma Scale [GCS] score of 9-12). Patient characteristics, injury mechanism, details of intracranial injury, treatment, and outcome were investigated...
March 29, 2024: Journal of Neurosurgery
https://read.qxmd.com/read/38544615/interhemispheric-acute-subdural-hematoma-secondary-to-falx-meningioma-a-case-report
#28
Kiyotaka Ogasawara, Yuhei Ito, Tsuyoshi Ichikawa, Kyouichi Suzuki
This report describes an unusual case of falx meningioma associated with acute subdural hematoma, which is a rare presentation. A 76-year-old woman presented with right-sided hemiparesis and a known falx meningioma that had rapidly increased in volume over the previous year. Computed tomography revealed interhemispheric and left-hemispheric acute subdural hematomas. Preoperative embolization and surgical tumor removal were performed to improve the symptoms, and pathological examination of the tumor revealed transitional meningioma (WHO Grade I)...
February 2024: Curēus
https://read.qxmd.com/read/38539274/tetralogy-of-fallot-complicated-by-multiple-cerebral-abscesses-in-a-child-a-case-report
#29
JOURNAL ARTICLE
Larrey Kasereka Kamabu, Franck Katembo Sikakulya, Louange Maha Kataka, Bives Nzanzu Mutume Vivalya, Hervé Monka Lekuya, Doomwin Oscar Deogratius Obiga, Juliet Nalwanga Sekabunga, Godfrey S Bbosa
INTRODUCTION: Brain abscesses are rare but potentially fatal condition and can be associated with cyanotic congenital heart disease of which 5-18.7% of these patients that develop cerebral abscess commonly have tetralogy of Fallot (TOF). CASE PRESENTATION: We report a case of 3-year-old Muganda male that presented with convulsions, cyanosis and difficulty in breathing. The patient had a combination intervention of medical treatment and surgical drainage of the abscess...
March 28, 2024: Journal of Medical Case Reports
https://read.qxmd.com/read/38538863/irrigation-versus-no-irrigation-in-the-treatment-of-chronic-subdural-hematoma-an-updated-systematic-review-and-meta-analysis-of-1581-patients
#30
REVIEW
Ahmed Aljabali, Ibrahim Serag, Sherein Diab, Abdulhameed Zeyad Alhadeethi, Mariam Abdelhady, Ibraheem M Alkhawaldeh, Mohamed Abouzid
Burr hole craniotomy is a common technique employed in the treatment of chronic subdural hematoma. However, its effectiveness and the occurrence of additional complications with various irrigation techniques utilized during the surgery remain unclear. The paper aims to compare the effectiveness and safety of burr hole craniotomy with and without irrigation in the treatment of chronic subdural hematoma. We conducted a systematic review by searching PubMed, Cochrane Library, Scopus, Ovid, and Web of Science for comparative studies that fit the eligibility criteria...
March 28, 2024: Neurosurgical Review
https://read.qxmd.com/read/38537787/traumatic-falcine-artery-aneurysm-resulting-in-intracranial-hemorrhage
#31
JOURNAL ARTICLE
Shinya Tokunaga, Hiromasa Adachi, Akinori Miyakoshi
A 50-year-old man presented with mild unconsciousness after a fall-induced head injury. Initial imaging revealed a left-sided acute subdural hematoma. After transportation to our hospital, his condition deteriorated, leading to the discovery of a new hemorrhage and an anterior falcine artery aneurysm upon further examination. The patient underwent successful decompressive craniectomy and endovascular occlusion. This case, the first reported of a traumatic anterior falcine artery aneurysm, suggests the initial injury caused both the hematoma and aneurysm...
March 25, 2024: World Neurosurgery
https://read.qxmd.com/read/38532172/simulating-cerebral-edema-and-ischemia-after-traumatic-acute-subdural-hematoma-using-triphasic-swelling-biomechanics
#32
JOURNAL ARTICLE
Andrew V Basilio, Delin Zeng, Leanne A Pichay, Gerard A Ateshian, Peng Xu, Steve A Maas, Barclay Morrison
Poor outcome following traumatic acute subdural hematoma (ASDH) is associated with the severity of the primary injury and secondary injury including cerebral edema and ischemia. However, the underlying secondary injury mechanism contributing to elevated intracranial pressure (ICP) and high mortality rate remains unclear. Cerebral edema occurs in response to the exposure of the intracellular fixed charge density (FCD) after cell death, causing ICP to increase. The increased ICP from swollen tissue compresses blood vessels in adjacent tissue, restricting blood flow and leading to ischemic damage...
March 26, 2024: Annals of Biomedical Engineering
https://read.qxmd.com/read/38530411/impact-of-early-follow-up-ct-in-the-conservative-management-of-traumatic-brain-injury-on-surgical-decision-making-a-retrospective-single-center-analysis-with-special-respect-to-coagulopathy
#33
JOURNAL ARTICLE
Mats L Moskopp, Dag Moskopp, Lennart W Sannwald
INTRODUCTION: Initial management of traumatic brain injury (TBI) without immediate need for surgical therapy varies across centers. The additional value of routine repeat cranial computerized tomography (CT) to neurological monitoring is controversial. This retrospective study investigates the impact of routine follow-up CT after 6 h (CT6h) in initially conservatively managed TBI on surgical decision making. Furthermore, the impact of coagulopathy on lesion size and progression was examined...
March 26, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38522223/middle-meningeal-artery-embolization-reduces-recurrence-following-surgery-for-septated-chronic-subdural-hematomas
#34
JOURNAL ARTICLE
Juan Carlos Martinez-Gutierrez, Bryden H Dawes, Hussein A Zeineddine, William W Wroe, Salvatore A D'Amato, Hyun Woo Kim, Michael I Nahhas, Peng Roc Chen, Spiros L Blackburn, Sunil A Sheth, Ching-Jen Chen, Ashutosh Mahapatra, Ryan S Kitagawa, Mark J Dannenbaum
BACKGROUND: Septated chronic subdural hematomas (cSDH) have high rates of recurrence despite surgical evacuation. Middle meningeal artery embolization (MMAE) has emerged as a promising adjuvant for secondary prevention, yet its efficacy remains ill-defined. METHODS: This is a retrospective review of septated cSDH cases treated at our institution. The surgery-only group was derived from cases performed before 2018, and the surgery+MMAE group was derived from cases performed 2018 or later...
March 21, 2024: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38519018/correlating-age-and-hematoma-volume-with-extent-of-midline-shift-in-acute-subdural-hematoma-patients-validation-of-an-artificial-intelligence-tool-for-volumetric-analysis
#35
JOURNAL ARTICLE
Manisha Koneru, Umika Paul, Ujjwal Upadhyay, Swetha Tanamala, Satish Golla, Hamza A Shaikh, Ajith J Thomas, Corey M Mossop, Daniel A Tonetti
OBJECTIVE: Decision for intervention in acute subdural hematoma patients is based on a combination of clinical and radiographic factors. Age has been suggested as a factor to be strongly considered when interpreting MLS and hematoma volume data for assessing critical clinical severity during operative intervention decisions for acute subdural hematoma patients. The objective of this study was to demonstrate the use of an automated volumetric analysis tool to measure hematoma volume and midline shift (MLS) and quantify their relationship with age...
March 20, 2024: World Neurosurgery
https://read.qxmd.com/read/38515352/middle-meningeal-artery-embolization-for-the-treatment-of-unilateral-large-chronic-subdural-hematoma-patients-with-significant-midline-shift-a-single-center-experience
#36
JOURNAL ARTICLE
Yin Niu, Qiang Zhang, Zhouyang Jiang, Wenyan Li, Zhi Chen
BACKGROUND: The amount of midline shift (MLS) considered safe for middle meningeal artery embolization (MMAE) in patients with chronic subdural hematoma (CSDH) has not been established. Whether MMAE could be used as upfront treatment for unilateral large CSDH patients with significant MLS (>1 cm) has not been reported. OBJECTIVE: To investigate the efficacy and safety of MMAE in unilateral large CSDH patients with MLS > 1 cm. METHODS: Eleven carefully selected CSDH patients with mild or moderate symptoms and significant MLS > 1 cm from 1 May 2021 to 31 August 2022 were included in the study...
March 22, 2024: Interventional Neuroradiology
https://read.qxmd.com/read/38514587/incidence-of-surgically-treated-chronic-subdural-hematoma-after-head-injury-with-normal-initial-computed-tomography
#37
JOURNAL ARTICLE
Aaro Heinonen, Minna Rauhala, Harri Isokuortti, Rahul Raj, Anneli Kataja, Milaja Nikula, Juha Öhman, Grant L Iverson, Teemu Luoto
PURPOSE: The objective was to determine the incidence of surgically treated chronic subdural hematoma (cSDH) within six months after head trauma in a consecutive series of head injury patients with a normal initial computed tomography (CT). METHODS: A total of 1941 adult patients with head injuries who underwent head CT within 48 h after injury and were treated at the Tampere University Hospital's emergency department were retrospectively evaluated from medical records (median age = 59 years, IQR = 39-79 years, males = 58%, patients using antithrombotic medication = 26%)...
March 22, 2024: Acta Neurochirurgica
https://read.qxmd.com/read/38510617/the-spectrum-of-acute-and-chronic-consequences-of-neurotrauma-in-professional-and-amateur-boxing-a-call-to-action-is-advocated-to-better-understand-and-prevent-this-phenomenon
#38
REVIEW
Michele Da Broi, Abdullah Al Awadhi, Philippe Voruz, Aria Nouri, Karl Schaller
INTRODUCTION: Despite changes in regulations, boxing-related injuries and fatalities are still occurring. The numbers available in the literature regarding mortality and long-term consequences may not accurately represent the actual situation. Indeed, the real extent of this phenomenon remains poorly known. RESEARCH QUESTION: Delineating the spectrum of acute and chronic consequences of boxing-related traumatic brain injuries (TBI). MATERIAL AND METHODS: Narrative review of the literature concerning acute and chronic boxing-related TBI...
2024: Brain Spine
https://read.qxmd.com/read/38510534/misleading-rare-case-of-idiopathic-hypertrophic-pachymeningitis
#39
Ahmad Rezaee Azandaryani, Amir Mohammad Salehi
Idiopathic hypertrophic pachymeningitis (IHP) is a rare disease with diffuse thickening of the dura mater that has no specific clinical symptoms and manifestations and it causes neurosurgeons to misdiagnose. A 4-year-old girl presented at the emergency room of our hospital with speech difficulty and severe headache. Head computed tomography scans (CT scan) on admission revealed a large fluid collection over the right temporoparietal region with mass effect, and the neurosurgeon drained it with the initial diagnosis of subdural hematoma...
2024: Case Reports in Medicine
https://read.qxmd.com/read/38507988/a-nomogram-for-predicting-the-possibility-of-effusion-deterioration-in-patients-with-traumatic-subdural-effusion
#40
JOURNAL ARTICLE
Mingang Zou, Defang Luo, Weilong Huang, Ruijin Yang, Qiuhua Jiang, Qianliang Huang
BACKGROUND: Traumatic subdural effusion (TSDE) may increase progressively or evolve into chronic subdural hematoma. These events, defined as deterioration of the effusion, often require close observation or even surgical treatment. The aim of our study was to develop and validate a nomogram for predicting the possibility of an effusion deteriorating in patients with TSDE based on the available clinical characteristics. METHODS: Clinical data from 78 patients with TSDE were retrospectively analyzed...
March 15, 2024: Clinical Neurology and Neurosurgery
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