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https://www.readbyqxmd.com/read/28430260/optical-performance-enhancement-of-chip-on-board-light-emitting-diodes-through-ionic-wind-patterning
#1
Jiading Wu, Jingcao Chu, Zefeng Zhang, Jiahui Huang, Huai Zheng, Sheng Liu
Due to the total internal reflection at the upper interface of the encapsulation layer, the light extraction efficiency (LEE) of chip-on-board packaging light-emitting diodes is attenuated significantly. It is well known that the LEE can be enhanced by patterning the encapsulation layer. In this study, a novel method of patterning the encapsulation layer, which is based on the interaction between the ionic wind and liquid encapsulation, is proposed and demonstrated. Two kinds of encapsulation patterns, namely dual stripe and meniscus, were fabricated successfully...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28430210/folded-monocentric-imager-with-deformable-mirror-focus
#2
Glenn M Schuster, William M Mellette, Joseph E Ford
We describe a catadioptric monocentric imager using an elastic central element focused by deformation of a fold mirror. We show the design of 6 mm and 12 mm focal length F/2.8 achromats and compare design performance when focusing by translating the sensor, translating the fold mirror, and by spherically deforming the fold mirror. We tested the 12 mm focal length design using a diamond turned polystyrene element as the outer meniscus lens (and mechanical mount), filled with an optical gel in contact with the central aperture and fold mirror, and demonstrate focusing by mechanical deformation of the fold mirror...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28425824/isolated-acl-versus-multiple-knee-ligament-injury-associations-with-patient-characteristics-cartilage-status-and-meniscal-tears-identified-during-acl-reconstruction
#3
Ronald W B Wyatt, Maria C S Inacio, Kate D Bellevue, Alan L Schepps, Gregory B Maletis
OBJECTIVES: The objectives of this study were to determine (1) if patients undergoing reconstruction of an isolated anterior cruciate ligament (ACL) tear had different characteristics (age, gender, body mass index [BMI]) than patients undergoing ACL reconstruction (ACLR) with multiple knee ligament (MKL) tears and (2) whether there was a difference in prevalence of articular cartilage injury and meniscus tears between these two groups. METHODS: Patients undergoing primary ACLR between February 2005 and September 2013 were identified through an ACLR registry...
April 20, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28425757/the-prevalence-and-characteristics-of-a-subcortical-cystic-lesion-at-the-subspinous-region-of-the-knee
#4
Ji Ye Son, Young Cheol Yoon, Wook Jin, Jang Gyu Cha
Background Although we observed that subcortical cysts near the attachment of the meniscus or cruciate ligaments are frequently seen with a tear or degeneration of the adjacent meniscus and/or cruciate ligament, there is no large study describing the prevalence, distribution, and associated findings of these cysts. Purpose To evaluate the prevalence and distribution of subcortical cysts near the attachments of the meniscus or cruciate ligaments and evaluate pathologies of the meniscus or cruciate ligaments using magnetic resonance imaging (MRI)...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28420447/ck2-1-a-bone-morphogenetic-protein-receptor-type-ia-mimetic-peptide-repairs-cartilage-in-mice-with-destabilized-medial-meniscus
#5
Hemanth Akkiraju, Padma Pradeepa Srinivasan, Xian Xu, Xinqiao Jia, Catherine B Kirn Safran, Anja Nohe
BACKGROUND: Osteoarthritis (OA) of the knee involves degeneration of articular cartilage of the diarthrodial joints. Current treatment options temporarily relieve the joint pain but do not restore the lost cartilage. We recently designed a novel bone morphogenetic protein receptor type I (BMPRI) mimetic peptide, CK2.1, that activates BMPRIa signaling in the absence of bone morphogenetic protein (BMP). Our previous research demonstrated that CK2.1 induced chondrogenesis in vitro and in vivo; however, it is unknown if CK2...
April 18, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28416188/a-giraffe-neck-sign-of-the-medial-meniscus-a-characteristic-finding-of-the-medial-meniscus-posterior-root-tear-on-magnetic-resonance-imaging
#6
Takayuki Furumatsu, Masataka Fujii, Yuya Kodama, Toshifumi Ozaki
BACKGROUND: The posterior root ligament of the medial meniscus (MM) has a critical role in regulating the MM movement. An accurate diagnosis of the MM posterior root tear (MMPRT) using magnetic resonance imaging (MRI) is important for preventing sequential osteoarthritis following the MMPRT. However, diagnosis of the MMPRT is relatively difficult even after using several characteristic MRI findings. The aim of this study was to identify a useful meniscal body sign of the MMPRT for improving diagnostic MRI reading...
April 13, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28413859/meniscus-articular-cartilage-and-nucleus-pulposus-a-comparative-review-of-cartilage-like-tissues-in-anatomy-development-and-function
#7
REVIEW
Song Chen, Peiliang Fu, Haishan Wu, Ming Pei
The degradation of cartilage in the human body is impacted by aging, disease, genetic predisposition and continued insults resulting from daily activity. The burden of cartilage defects (osteoarthritis, rheumatoid arthritis, intervertebral disc damage, knee replacement surgeries, etc.) is daunting in light of substantial economic and social stresses. This review strives to broaden the scope of regenerative medicine and tissue engineering approaches used for cartilage repair by comparing and contrasting the anatomical and functional nature of the meniscus, articular cartilage (AC) and nucleus pulposus (NP)...
April 17, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28412106/radial-notch-labralization-for-proximal-radioulnar-joint-dysplasia
#8
Enrico Bellato, Shawn W O'Driscoll
BACKGROUND: Chronic posterior subluxation or dislocation of the radial head is uncommon and difficult to treat. To restore radiocapitellar alignment, procedures such as deepening of the notch using a high-speed burr have been described, but they can result in cartilage damage. We hypothesized that a radial notch labralization using soft tissue could improve radiocapitellar tracking without violating the joint surface. METHODS: A radial notch labralization was performed in 3 patients with chronic posterior subluxation of the radial head and developmental dysplasia of the radial notch in the setting of complex recurrent instability of the elbow...
April 12, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28411813/voltammetric-determination-of-trace-amounts-of-diacetyl-at-a-mercury-meniscus-modified-silver-solid-amalgam-electrode-following-gas-diffusion-microextraction
#9
Rui M Ramos, Luís M Gonçalves, Vlastimil Vyskočil, José A Rodrigues
A new approach was developed for the determination of trace amounts of diacetyl in food products using gas-diffusion microextraction (GDME) and subsequent detection by differential pulse voltammetry (DPV) at a mercury meniscus modified silver solid amalgam electrode (m-AgSAE). Diacetyl is a vicinal diketone responsible for the buttery aroma in many fermented foods and beverages. Its determination is important not only for evaluation of the final product quality (note of mention: health related concerns were associated with continuous diacetyl exposure) but also to monitor fermentation...
July 1, 2017: Talanta
https://www.readbyqxmd.com/read/28409107/a-transosseous-bone-bridge-repair-for-posterior-horn-meniscal-root-tears-during-anterior-cruciate-ligament-reconstruction
#10
Jonathan M Frank, Daniel J Liechti, Jack Anavian, Thomas R Hackett
Meniscal root tears occur in isolation or concurrently with ligamentous knee injury and cause significantly altered knee mechanics with the loss of normal meniscus hoop stress. This loss of normal meniscus function can result in abnormal knee kinematics and, subsequently, more rapid degenerative changes of the knee articular surface. In the setting of anterior cruciate ligament tear, the posterolateral meniscus root is most commonly damaged. Several techniques exist for meniscus root repair; however, none have been shown to be clearly superior...
February 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28407495/stem-cell-delivery-in-tissue-specific-hydrogel-enabled-meniscal-repair-in-an-orthotopic-rat-model
#11
Xiaoning Yuan, Yiyong Wei, Aránzazu Villasante, Johnathan J D Ng, Derya E Arkonac, Pen-Hsiu Grace Chao, Gordana Vunjak-Novakovic
Interest in non-invasive injectable therapies has rapidly risen due to their excellent safety profile and ease of use in clinical settings. Injectable hydrogels can be derived from the extracellular matrix (ECM) of specific tissues to provide a biomimetic environment for cell delivery and enable seamless regeneration of tissue defects. We investigated the in situ delivery of human mesenchymal stem cells (hMSCs) in decellularized meniscus ECM hydrogel to a meniscal defect in a nude rat model. First, decellularized meniscus ECM hydrogel retained tissue-specific proteoglycans and collagens, and significantly upregulated expression of fibrochondrogenic markers by hMSCs versus collagen hydrogel alone in vitro...
April 4, 2017: Biomaterials
https://www.readbyqxmd.com/read/28407360/the-anterolateral-ligament-a-cadaveric-study-in-foetuses
#12
Ainhoa Nekane Toro-Ibarguen, Juan Pretell-Mazzini, Elena Pérez, Isabel Pedrajas, Juan Miguel Cano-Egea, Jose Ramón Sanudo
INTRODUCTION: The aim of this study was to determine the presence and morphology of the anterolateral ligament (ALL) of the knee in a sample of fetuses. We hypothesized that the ALL is present in sample fetuses and its origin is not related to repetitive stresses throughout life. MATERIAL & METHODS: Forty fresh-frozen knees from cadaveric fetuses were dissected using a standard technique. The ALL and other structures in the anterolateral compartment of the knee were identified...
April 13, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28406879/physical-examination-of-the-knee-meniscus-cartilage-and-patellofemoral-conditions
#13
Robert D Bronstein, Joseph C Schaffer
The knee is one of the most commonly injured joints in the body. Its superficial anatomy enables diagnosis of the injury through a thorough history and physical examination. Examination techniques for the knee described decades ago are still useful, as are more recently developed tests. Proper use of these techniques requires understanding of the anatomy and biomechanical principles of the knee as well as the pathophysiology of the injuries, including tears to the menisci and extensor mechanism, patellofemoral conditions, and osteochondritis dissecans...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28400662/early-anterior-cruciate-ligament-reconstruction-can-save-meniscus-without-any-complications
#14
Chang-Ik Hur, Eun-Kyoo Song, Sung-Kyu Kim, Seung-Hun Lee, Jong-Keun Seon
BACKGROUND: Early ACL reconstruction, before retuning to activity eliminates recurrent episodes of instability and thereby decreases chances of meniscal and cartilage injury. However, there are no clear and uniform guidelines regarding the timing of ACL reconstruction or clarity in the definition of early and delayed reconstruction to reduce the complications after reconstruction in the ACL injured knee. The purpose of this study was to compare the clinical outcome, stability, muscle power, and postural control after early and delayed anterior cruciate ligament (ACL) reconstruction...
March 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28397004/the-frequency-of-cartilage-lesions-in-non-injured-knees-with-symptomatic-meniscus-tears-results-from-an-arthroscopic-and-nir-near-infrared-spectroscopic-investigation
#15
Gunter Spahn, Holger Plettenberg, Martin Hoffmann, Holm-Torsten Klemm, Christoph Brochhausen-Delius, Gunther O Hofmann
INTRODUCTION: Are symptomatic tear injuries to the menisci of the knee frequently or always associated with cartilage damage to the corresponding articular surfaces and other joint surfaces, respectively? METHODS: A total of 137 patients (medial n = 127; lateral n = 10) underwent a meniscus resection. These patients showed no signs of a clear radiographic arthrosis and no MRI-detectable cartilage lesions > grade II. Traumatic injury was ruled out with a thorough medical history...
April 10, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28393321/usability-and-reproducibility-of-tear-meniscus-values-generated-via-swept-source-optical-coherence-tomography-and-the-slit-lamp-with-a-graticule-method
#16
Hitoshi Imamura, Hitoshi Tabuchi, Shunsuke Nakakura, Daisuke Nagasato, Hiroaki Baba, Yoshiaki Kiuchi
PURPOSE: To investigate the usability and the reproducibility of the tear meniscus values via swept-source optical coherence tomography (SS-OCT) and the conventional slit lamp microscope method with a graticule. METHODS: The right eye was examined in 90 healthy adult subjects who were grouped according to age (group 1: 20-39 years; group 2: 40-59 years; group 3: ≥60 years). The tear meniscus height (TMH) and tear meniscus area were measured using SS-OCT and TMH by the slit lamp microscope method...
April 9, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28383764/risk-factors-for-radiographic-joint-space-narrowing-and-patient-reported-outcomes-of-post-traumatic-osteoarthritis-after-acl-reconstruction-data-from-the-moon-cohort
#17
Morgan H Jones, Kurt P Spindler
The Multicenter Orthopaedic Outcomes Network (MOON) is an NIH-funded prospective, longitudinal cohort of over 3500 patients who have undergone anterior cruciate ligament reconstruction (ACLR) by 14 sports medicine surgeons at 7 academic medical centers. Patient reported outcome questionnaires (PRO's) are completed at baseline and multiple timepoints after surgery, and a nested cohort of patients return for radiographs to assess the development of joint space changes. We review the risk factors for worse patient reported outcomes, the predictors of clinically significant symptoms of post-traumatic osteoarthritis (PTOA), and the factors associated with more radiographic joint space narrowing...
April 6, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28380690/chemogenetic-inhibition-of-pain-neurons-in-a-mouse-model-of-osteoarthritis
#18
Rachel E Miller, Shingo Ishihara, Bula Bhattacharyya, Ada Delaney, Daniela M Menichella, Richard J Miller, Anne-Marie Malfait
Objective - The purpose of this study was to determine the ability of drugs that activate inhibitory G-protein coupled receptors (GPCRs) expressed in peripheral NaV 1.8-positive sensory neurons to control osteoarthritis associated pain. Therefore, we used Designer Receptors Exclusively Activated by a Designer Drug (DREADD) technology, which utilizes engineered GPCRs to activate or inhibit neurons upon binding the synthetic ligand, clozapine-N-oxide. Methods -NaV 1.8-Pdi C57BL/6 mice were created to express the inhibitory DREADD receptor, Pdi, in NaV 1...
April 5, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28378793/effects-of-a-warm-compress-containing-menthol-on-the-tear-film-in-healthy-subjects-and-dry-eye-patients
#19
Reiko Arita, Naoyuki Morishige, Ichiro Sakamoto, Natsuko Imai, Yuko Shimada, Michihito Igaki, Atsushi Suzuki, Kouzo Itoh, Kazuo Tsubota
Menthol is thought to stimulate lacrimation via activation of cold-sensitive primary afferent neurons in the cornea. We evaluated a warm compress containing menthol as a potential treatment for dry eye by examining its effects on the tear film in healthy subjects (n = 20) and dry eye patients (n = 35). Disposable eyelid-warming steamers that either did (MH) or did not (HO) contain menthol were applied to one eye of each subject either once only for 10 min or repeatedly over 2 weeks. Single application of MH significantly increased tear meniscus volume (P = 8...
April 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28378451/association-between-medial-meniscus-extrusion-and-spontaneous-osteonecrosis-of-the-knee
#20
Tadashi Yasuda, Satoshi Ota, Satoshi Fujita, Eijiro Onishi, Koichi Iwaki, Hiroshi Yamamoto
AIM: Medial meniscus tear has been proposed as a potential etiology of spontaneous osteonecrosis of the knee (SONK). Disruption of collagen fibers within the meniscus causes meniscal extrusion, which results in alteration in load distribution in the knee. Our purpose was to determine whether the extent of medial meniscus extrusion correlates with the severity of SONK in the medial femoral condyle. METHODS: Radiological stage of SONK and femorotibial angle (FTA) were determined on knee radiographs...
April 5, 2017: International Journal of Rheumatic Diseases
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