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Huang he-feng

Junlei He, Meixin Feng, Yaozong Zhong, Jin Wang, Rui Zhou, Hongwei Gao, Yu Zhou, Qian Sun, Jianxun Liu, Yingnan Huang, Shuming Zhang, Huaibing Wang, Masao Ikeda, Hui Yang
Direct bandgap III-V semiconductor lasers grown on silicon (Si) are highly desired for monolithic integration with Si photonics. Fabrication of semiconductor lasers with a Fabry-Pérot cavity usually includes facet cleavage, however, that is not compatible with on-chip photonic integration. Etching as an alternative approach holds a great advantage in preparing cavity mirrors with no need of breaking wafer into bars. However, gallium nitride (GaN) sidewalls prepared by dry etching often have a large roughness and etching damages, which would cause mirror loss due to optical scattering and carrier injection loss because of surface non-radiative recombination...
May 21, 2018: Scientific Reports
Cheng Chang, Minghui Wu, Dongsheng He, Yanling Pei, Chao-Feng Wu, Xuefeng Wu, Hulei Yu, Fangyuan Zhu, Kedong Wang, Yue Chen, Li Huang, Jing-Feng Li, Jiaqing He, Li-Dong Zhao
Thermoelectric technology enables the harvest of waste heat and its direct conversion into electricity. The conversion efficiency is determined by the materials figure of merit ZT Here we show a maximum ZT of ~2.8 ± 0.5 at 773 kelvin in n-type tin selenide (SnSe) crystals out of plane. The thermal conductivity in layered SnSe crystals is the lowest in the out-of-plane direction [two-dimensional (2D) phonon transport]. We doped SnSe with bromine to make n-type SnSe crystals with the overlapping interlayer charge density (3D charge transport)...
May 18, 2018: Science
Qiang Cai, Lulu Qiao, Ming Wang, Baoye He, Feng-Mao Lin, Jared Palmquist, Hsien-Da Huang, Hailing Jin
Some pathogens and pests deliver small RNAs (sRNAs) into host cells to suppress host immunity. Conversely, hosts also transfer sRNAs into pathogens and pests to inhibit their virulence. Although sRNA trafficking has been observed in a wide variety of interactions, how sRNAs are transferred, especially from hosts to pathogens/pests, is still unknown. Here we show that host Arabidopsis cells secrete exosome-like extracellular vesicles to deliver sRNAs into fungal pathogen Botrytis cinerea These sRNA-containing vesicles accumulate at the infection sites and are taken up by the fungal cells...
May 17, 2018: Science
Tian Fang, Dan-Dan Liu, He-Ming Ning, Dan Liu, Jing-Ya Sun, Xiao-Jing Huang, Yu Dong, Mei-Yu Geng, Shi-Feng Yun, Jun Yan, Rui-Min Huang
Modified citrus pectin (MCP) is a carbohydrate enriched complex, which has been implicated in cancer treatment and prevention. However, the effects of MCP on urinary bladder cancer (UBC) are unknown. In this study, MCP was first tested in T24 and J82 human UBC cells and showed the inhibition of cell viability by the sulforhodamine B (SRB) assay. The MCP-treated UBC cells exhibited G2 /M phase arrest with the decrease of Cyclin B1 and phosphorylated Cdc2. Caspase-3 was also activated, leading to the cleavage of Caspase-3 and PARP...
May 16, 2018: Acta Pharmacologica Sinica
Li-Rong Wu, Huan-Feng Zhu, Jianhua Xu, Xue-Song Jiang, Li Yin, Ning Jiang, Dan Zong, Fei-Jiang Wang, Sheng-Fu Huang, Xiu-Hua Bian, Jian-Feng Wu, Dan Song, Wen-Jie Guo, Ju-Ying Liu, Xia He
Background : This study aimed to compare concurrent chemoradiotherapy (CCRT) plus cetuximab (C) with CCRT alone in locoregionally advanced nasopharyngeal carcinoma(NPC). Methods : A total of 682 locoregionally advanced NPC patients who had undergone chemoradiotherapy with or without cetuximab were included. Propensity score-matching method was used to match patients. Progression-free survival (PFS), overall survival (OS), locoregional relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) were compared between the two treatment arms...
2018: Journal of Cancer
Shuai-Bing Zhang, Zheng-Hui Li, Marc Stadler, He-Ping Chen, Ying Huang, Xiao-Qing Gan, Tao Feng, Ji-Kai Liu
Eight undescribed lanostane triterpenoids, pardinols A‒H, along with one previously reported lanostane triterpenoid, namely saponaceol B, were isolated from the fruiting bodies of Tricholoma pardinum. Their structures and stereoconfigurations were established via combination of extensive spectroscopic analyses, alkaline methanolysis method and TDDFT/ECD calculations. Pardinols B and E-H exhibited certain inhibition activities of nitric oxide (NO) production with IC50 value ranging from 5.3 to 14.7 μM, as well as cytotoxicities against human cancer cell-lines...
May 11, 2018: Phytochemistry
Wen Yi Huo, Zhichao Li, Yao-Hua Chen, Xufei Xie, Guoli Ren, Hui Cao, Shu Li, Ke Lan, Jie Liu, Yongsheng Li, Sanwei Li, Liang Guo, Yonggang Liu, Dong Yang, Xiaohua Jiang, Lifei Hou, Huabing Du, Xiaoshi Peng, Tao Xu, Chaoguang Li, Xiayu Zhan, Zhebin Wang, Keli Deng, Qiangqiang Wang, Bo Deng, Feng Wang, Jiamin Yang, Shenye Liu, Shaoen Jiang, Guanghui Yuan, Haijun Zhang, Baibin Jiang, Wei Zhang, Qianqian Gu, Zhibing He, Kai Du, Xuewei Deng, Wei Zhou, Liquan Wang, Xiaoxia Huang, Yuancheng Wang, Dongxia Hu, Kuixing Zheng, Qihua Zhu, Yongkun Ding
The first octahedral spherical hohlraum energetics experiment is accomplished at the SGIII laser facility. For the first time, the 32 laser beams are injected into the octahedral spherical hohlraum through six laser entrance holes. Two techniques are used to diagnose the radiation field of the octahedral spherical hohlraum in order to obtain comprehensive experimental data. The radiation flux streaming out of laser entrance holes is measured by six flat-response x-ray detectors (FXRDs) and four M-band x-ray detectors, which are placed at different locations of the SGIII target chamber...
April 20, 2018: Physical Review Letters
Xiaoyan Li, Gang Peng, Feng Cui, Qianying Qiu, Xiaojun Chen, He Huang
An ultrasensitive electrochemical genosensor has been fabricated for the double determination of two different specific sequences deduced from the maternally expressed gene3 (MEG3) lncRNA (long noncoding RNA), which was demonstrated by coupling RNase A-aided target recycling with DNA supersandwich-induced signal enhancement, based on a composite interface of graphene-like tungsten disulfide/dendritic gold nanostructures (WS2 /DGN). Firstly, duple target sequences of T1 and T2 were captured by the primer probes of P1 /P2 functionalized Fe3 O4 @C magnetic nanoparticles, via the DNA/RNA hybridization between T1 /T2 and P1 /P2 ...
May 2, 2018: Biosensors & Bioelectronics
Chenyi Sheng, Jian Qiu, Yingying Wang, Zhixian He, Hua Wang, Qingqing Wang, Yeqing Huang, Lianxin Zhu, Feng Shi, Yingying Chen, Shiyao Xiong, Zhen Xu, Qichao Ni
Breast cancer is the second leading cause of cancer‑associated mortality in women worldwide. Strong evidence has suggested that Ran, which is a small GTP binding protein involved in the transport of RNA and protein across the nucleus, may be a key cellular protein involved in the metastatic progression of cancer. The present study investigated Ran gene expression in breast cancer tissue samples obtained from 140 patients who had undergone surgical resection for breast cancer. Western blot analysis of Ran in breast cancer tissues and paired adjacent normal tissues showed that expression of Ran was significantly increased in breast cancer tissues...
May 3, 2018: Molecular Medicine Reports
Liping Fan, Danhui Fu, Jinquan Hong, Haobo Huang, Wenqian He, Feng Zeng, Qiuyan Lin, Qianling Xie
The current study sought to evaluate whether blood transfusions affect survival of elderly patients with primary diffuse large B-cell lymphoma (DLBCL). A total of 104 patients aged 60 years and over were enrolled and divided into two groups: 24 patients who received transfusions and 80 patients who did not. Statistical analyses showed significant differences in LDH levels, platelet (Plt) counts, and hemoglobin (Hb) and albumin (Alb) levels between the two groups. Univariate analyses showed that LDH level ≥ 245 IU/L, cell of origin (germinal center/nongerminal center), and blood transfusion were associated with both overall survival (OS) and progression-free survival (PFS)...
2018: BioMed Research International
Sai Ge, Xia Xia, Chen Ding, Bei Zhen, Quan Zhou, Jinwen Feng, Jiajia Yuan, Rui Chen, Yumei Li, Zhongqi Ge, Jiafu Ji, Lianhai Zhang, Jiayuan Wang, Zhongwu Li, Yumei Lai, Ying Hu, Yanyan Li, Yilin Li, Jing Gao, Lin Chen, Jianming Xu, Chunchao Zhang, Sung Yun Jung, Jong Min Choi, Antrix Jain, Mingwei Liu, Lei Song, Wanlin Liu, Gaigai Guo, Tongqing Gong, Yin Huang, Yang Qiu, Wenwen Huang, Tieliu Shi, Weimin Zhu, Yi Wang, Fuchu He, Lin Shen, Jun Qin
The original version of this Article contained an error in the email address of the corresponding author Jun Qin. The correct email is The error has been corrected in the HTML and PDF versions of the Article.
May 8, 2018: Nature Communications
Gang Peng, Xiaoyan Li, Feng Cui, Qianying Qiu, Xiaojun Chen, He Huang
In the food safety evaluation, aflatoxin B1 (AFB1) is an important indicator. In this work, we developed an AFB1 electrochemical aptasensor based on tetrahedral DNA nanostructures (TDNs) immobilized three dimensionally ordered macroporous MoS2-AuNPs hybrid (3DOM MoS2-AuNPs) recognition interface and horseradish peroxidase (HRP) functionalized magnetic signal amplifier. To greatly enhance the recognition efficiency, sensitivity and stability of the aptasensor, the AFB1 aptamer-incorporated TDNs were ingeniously combined with the 3DOM MoS2-AuNPs film for the construction of the sensing interface...
May 7, 2018: ACS Applied Materials & Interfaces
Ming-Fang Li, Yu-Huan Li, Ying-Hua He, Qin Wang, Ying Zhang, Xiao-Feng Li, Xiao-Ming Meng, Cheng Huang, Jun Li
Circular RNAs (circRNAs) are non-coding RNAs that play key roles in the pathogenesis of diseases and are associated with human hepatocellular carcinoma (HCC). Previous reports have shown the circRNA hsa_circ_0005075 is highly expressed in HCC tissues, but its function is unknown. In this study, we confirmed circ_0005075 is significantly increased in HCC tissues and cell lines. This overexpression was associated with increased numbers of proliferative, migrated and invasive SMMC-7721 cells. In addition, hsa_circ_0005075 inhibited the transcription activity of miR-431 measured by dual-luciferase reporter assays...
March 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Xian-Hu Zha, Ji-Chang Ren, Li Feng, Xiaojing Bai, Kan Luo, Yaqing Zhang, Jian He, Qing Huang, Joseph S Francisco, Shiyu Du
MXenes represent a new family of two-dimensional materials that have attracted considerable attention in recent years. Because of the remarkably different structures of Sc2C(OH)2 and Sc2CO2 MXene and their recently reported properties, this study explored the structural evolution and mechanism of chemical conversion between these two MXenes. Using first-principles density functional theory (DFT), the mechanism for dehydrogenation/hydrogenation is investigated by gradually removing/adding surface hydrogen atoms for Sc2C(OH)2/Sc2CO2 supercells...
April 30, 2018: Nanoscale
Xiu-Feng Huang, Lue Xiang, Wan Cheng, Fei-Fei Cheng, Kai-Wen He, Bo-Wen Zhang, Si-Si Zheng, Ru-Yi Han, Yi-Han Zheng, Xiao-Tao Xu, Huan-Yun Yu, Wenjuan Zhuang, Yuk Fai Leung, Zi-Bing Jin
Ocular coloboma is a developmental structural defect of the eye that often occurs as complex ocular anomalies. However, its genetic etiology remains largely unexplored. Here we report the identification of mutation (c.331C>T, p.R111C) in the IPO13 gene in a consanguineous family with ocular coloboma, microphthalmia, and cataract by a combination of whole-exome sequencing and homozygosity mapping. IPO13 encodes an importin-B family protein and has been proven to be associated with the pathogenesis of coloboma and microphthalmia...
April 27, 2018: Experimental & Molecular Medicine
Renyao Huang, Li He, Tao Zhang, Dianqing Li, Pinggui Tang, Yingying Zhao, Yongjun Feng
Magnesium silicate as a high-performance adsorption material has attracted increasing attention for the removal of organic dye pollution. Here, we prepared a series of magnesium silicate hydrates (MSH) in a hydrothermal route, and carefully investigated the corresponding adsorption behavior towards methylene blue (MB) as well as the effect of surface charge on adsorption capacity. The results show that surface charge plays a key role in the adsorption performance of MSH for MB, a negative surface charge density follows the increase of Si/Mg feeding ratio from 1...
April 24, 2018: Nanomaterials
M Ablikim, M N Achasov, S Ahmed, M Albrecht, M Alekseev, A Amoroso, F F An, Q An, J Z Bai, Y Bai, O Bakina, R Baldini Ferroli, Y Ban, K Begzsuren, D W Bennett, J V Bennett, N Berger, M Bertani, D Bettoni, F Bianchi, E Boger, I Boyko, R A Briere, H Cai, X Cai, O Cakir, A Calcaterra, G F Cao, S A Cetin, J Chai, J F Chang, G Chelkov, G Chen, H S Chen, J C Chen, M L Chen, P L Chen, S J Chen, X R Chen, Y B Chen, X K Chu, G Cibinetto, F Cossio, H L Dai, J P Dai, A Dbeyssi, D Dedovich, Z Y Deng, A Denig, I Denysenko, M Destefanis, F De Mori, Y Ding, C Dong, J Dong, L Y Dong, M Y Dong, Z L Dou, S X Du, P F Duan, J Fang, S S Fang, Y Fang, R Farinelli, L Fava, S Fegan, F Feldbauer, G Felici, C Q Feng, E Fioravanti, M Fritsch, C D Fu, Q Gao, X L Gao, Y Gao, Y G Gao, Z Gao, B Garillon, I Garzia, A Gilman, K Goetzen, L Gong, W X Gong, W Gradl, M Greco, M H Gu, Y T Gu, A Q Guo, R P Guo, Y P Guo, A Guskov, Z Haddadi, S Han, X Q Hao, F A Harris, K L He, X Q He, F H Heinsius, T Held, Y K Heng, T Holtmann, Z L Hou, H M Hu, J F Hu, T Hu, Y Hu, G S Huang, J S Huang, X T Huang, X Z Huang, Z L Huang, T Hussain, W Ikegami Andersson, Q Ji, Q P Ji, X B Ji, X L Ji, X S Jiang, X Y Jiang, J B Jiao, Z Jiao, D P Jin, S Jin, Y Jin, T Johansson, A Julin, N Kalantar-Nayestanaki, X S Kang, M Kavatsyuk, B C Ke, T Khan, A Khoukaz, P Kiese, R Kliemt, L Koch, O B Kolcu, B Kopf, M Kornicer, M Kuemmel, M Kuhlmann, A Kupsc, W Kühn, J S Lange, M Lara, P Larin, L Lavezzi, H Leithoff, C Li, Cheng Li, D M Li, F Li, F Y Li, G Li, H B Li, H J Li, J C Li, J W Li, Jin Li, K J Li, Kang Li, Ke Li, Lei Li, P L Li, P R Li, Q Y Li, W D Li, W G Li, X L Li, X N Li, X Q Li, Z B Li, H Liang, Y F Liang, Y T Liang, G R Liao, J Libby, C X Lin, D X Lin, B Liu, B J Liu, C X Liu, D Liu, F H Liu, Fang Liu, Feng Liu, H B Liu, H L Liu, H M Liu, Huanhuan Liu, Huihui Liu, J B Liu, J Y Liu, K Liu, K Y Liu, Ke Liu, L D Liu, Q Liu, S B Liu, X Liu, Y B Liu, Z A Liu, Zhiqing Liu, Y F Long, X C Lou, H J Lu, J G Lu, Y Lu, Y P Lu, C L Luo, M X Luo, X L Luo, S Lusso, X R Lyu, F C Ma, H L Ma, L L Ma, M M Ma, Q M Ma, T Ma, X N Ma, X Y Ma, Y M Ma, F E Maas, M Maggiora, Q A Malik, Y J Mao, Z P Mao, S Marcello, Z X Meng, J G Messchendorp, G Mezzadri, J Min, R E Mitchell, X H Mo, Y J Mo, C Morales Morales, N Yu Muchnoi, H Muramatsu, A Mustafa, Y Nefedov, F Nerling, I B Nikolaev, Z Ning, S Nisar, S L Niu, X Y Niu, S L Olsen, Q Ouyang, S Pacetti, Y Pan, M Papenbrock, P Patteri, M Pelizaeus, J Pellegrino, H P Peng, Z Y Peng, K Peters, J Pettersson, J L Ping, R G Ping, A Pitka, R Poling, V Prasad, H R Qi, M Qi, T Y Qi, S Qian, C F Qiao, N Qin, X S Qin, Z H Qin, J F Qiu, K H Rashid, C F Redmer, M Richter, M Ripka, M Rolo, G Rong, Ch Rosner, A Sarantsev, M Savrié, C Schnier, K Schoenning, W Shan, X Y Shan, M Shao, C P Shen, P X Shen, X Y Shen, H Y Sheng, X Shi, J J Song, W M Song, X Y Song, S Sosio, C Sowa, S Spataro, G X Sun, J F Sun, L Sun, S S Sun, X H Sun, Y J Sun, Y K Sun, Y Z Sun, Z J Sun, Z T Sun, Y T Tan, C J Tang, G Y Tang, X Tang, I Tapan, M Tiemens, B Tsednee, I Uman, G S Varner, B Wang, B L Wang, D Wang, D Y Wang, Dan Wang, K Wang, L L Wang, L S Wang, M Wang, Meng Wang, P Wang, P L Wang, W P Wang, X F Wang, Y Wang, Y D Wang, Y F Wang, Y Q Wang, Z Wang, Z G Wang, Z Y Wang, Zongyuan Wang, T Weber, D H Wei, J H Wei, P Weidenkaff, S P Wen, U Wiedner, M Wolke, L H Wu, L J Wu, Z Wu, L Xia, Y Xia, D Xiao, Y J Xiao, Z J Xiao, Y G Xie, Y H Xie, X A Xiong, Q L Xiu, G F Xu, J J Xu, L Xu, Q J Xu, Q N Xu, X P Xu, F Yan, L Yan, W B Yan, W C Yan, Y H Yan, H J Yang, H X Yang, L Yang, Y H Yang, Y X Yang, Yifan Yang, M Ye, M H Ye, J H Yin, Z Y You, B X Yu, C X Yu, J S Yu, C Z Yuan, Y Yuan, A Yuncu, A A Zafar, Y Zeng, Z Zeng, B X Zhang, B Y Zhang, C C Zhang, D H Zhang, H H Zhang, H Y Zhang, J Zhang, J L Zhang, J Q Zhang, J W Zhang, J Y Zhang, J Z Zhang, K Zhang, L Zhang, S Q Zhang, X Y Zhang, Y Zhang, Y H Zhang, Y T Zhang, Yang Zhang, Yao Zhang, Yu Zhang, Z H Zhang, Z P Zhang, Z Y Zhang, G Zhao, J W Zhao, J Y Zhao, J Z Zhao, Lei Zhao, Ling Zhao, M G Zhao, Q Zhao, S J Zhao, T C Zhao, Y B Zhao, Z G Zhao, A Zhemchugov, B Zheng, J P Zheng, Y H Zheng, B Zhong, L Zhou, Q Zhou, X Zhou, X K Zhou, X R Zhou, X Y Zhou, A N Zhu, J Zhu, K Zhu, K J Zhu, S Zhu, S H Zhu, X L Zhu, Y C Zhu, Y S Zhu, Z A Zhu, J Zhuang, B S Zou, J H Zou
The cross section of the e^{+}e^{-}→Λ_{c}^{+}Λ[over ¯]_{c}^{-} process is measured with unprecedented precision using data collected with the BESIII detector at sqrt[s]=4574.5, 4580.0, 4590.0 and 4599.5 MeV. The nonzero cross section near the Λ_{c}^{+}Λ[over ¯]_{c}^{-} production threshold is cleared. At center-of-mass energies sqrt[s]=4574.5 and 4599.5 MeV, the higher statistics data enable us to measure the Λ_{c} polar angle distributions. From these, the Λ_{c} electric over magnetic form-factor ratios (|G_{E}/G_{M}|) are measured for the first time...
March 30, 2018: Physical Review Letters
Shan Feng, Xin He, Peiru Zhong, Jinyi Zhao, Cong Huang, Zhuohan Hu
Radix Angelicae dahuricae , containing coumarins, which might affect cytochrome P450 enzyme (CYP450) activity, has been co-administered with ligustrazine, a substrate of CYP450s, for the clinical treatment of migraine. However, whether a pharmacokinetic-based synergy exists between Radix Angelicae dahuricae and ligustrazine is still unknown. In this study, the total coumarin extract (TCE) of Radix Angelicae dahuricae (50 mg/kg, orally) reinforced the anti-migraine activity of ligustrazine by declining head scratching, plasma calcitonin gene-related peptide, and serum nitric oxide, as well as increasing plasma endothelin levels in rats ( p < 0...
April 25, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Hai Huang, Chao Wang, Fei Liu, Hui-Zhen Li, Guang Peng, Xu Gao, Ke-Qin Dong, Hong-Ru Wang, De-Pei Kong, Min Qu, Li-He Dai, Kai-Jian Wang, Zhe Zhou, Jun Yang, Ze-Yu Yang, Yan-Qiong Cheng, Qin-Qin Tian, Dan Liu, Chuan-Liang Xu, Dan-Feng Xu, Xin-Gang Cui, Ying-Hao Sun
PURPOSE: Cancer stem-like cells (CSCs) contribute to the progression and androgen deprivation therapy (ADT) resistance of prostate cancer. Since CSCs depend on their specific niche, including tumor-associated macrophages (TAMs), elucidating the network between CSCs and TAMs may help to effectively inhibit the progression and ADT resistance of prostate cancer. EXPERIMENTAL DESIGN: The underlying intracellular mechanism that sustains the stem-like characteristics of CSCs in prostate cancer was assessed via RNA-seq, co-IP, ChIP and other assays...
April 24, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Mingzhen He, Jia Jia, Junmao Li, Bei Wu, Wenping Huang, Mi Liu, Yan Li, Shilin Yang, Hui Ouyang, Yulin Feng
Efficient targeted identification of chemical constituents from traditional Chinese medicine is still a major challenge. In this study, we used a characteristic ion filtering strategy to characterize compounds of Eucommia ulmoides Oliv. by ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry (UHPLC-ESI-Q-TOF-MS/MS). By using the ion filtering approach, target constituents of Eucommia ulmoides Oliv. were easily tentatively identified from the enormous LC/MS data set...
April 17, 2018: Journal of Chromatography. A
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