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Postpartum cardiomyopathy

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https://www.readbyqxmd.com/read/30104111/management-of-high-risk-cardiac-conditions-in-pregnancy-anticoagulation-severe-stenotic-valvular-disease-and-cardiomyopathy
#1
REVIEW
Emily Lau, Doreen DeFaria Yeh
Cardiovascular disease contributes to approximately one third of all maternal mortality and remains a significant source of peri‑ and postpartum morbidity. As more women at risk for and with cardiovascular disease are desiring pregnancy, it is imperative that general cardiologists and obstetricians participate collaboratively in preconception counseling and are more facile with management of these lesions during peri‑ and postpartum periods. This review aims to address this growing need and highlights the management strategies for some of the major high risk cardiac conditions encountered during pregnancy including anticoagulation, cardiomyopathies as well as severe mitral and aortic stenosis; aortopathy, pulmonary hypertension, and severe congenital heart lesions will not be addressed...
July 22, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30087040/reducing-late-maternal-death-due-to-cardiovascular-disease-a-pragmatic-pilot-study
#2
Karen Sliwa, Feriel Azibani, Johann Baard, Ayesha Osman, Liesl Zühlke, Anthony Lachmann, Elena Libhaber, Ashley Chin, Mpiko Ntsekhe, Priya Soma-Pillay, Mark R Johnson, Jolien Roos-Hesselink, John Anthony
BACKGROUND: Late maternal mortality (up-to 1-year postpartum) is poorly reported globally and is commonly due to cardiovascular disease (CVD). We investigated targeted interventions aiming at reducing peripartum heart failure admission and late maternal death. METHODS AND RESULTS: Prospective single-centre study of 269 peripartum women presenting with CVD in pregnancy, or within 6-months postpartum. Both cardiac disease maternity (CDM) Group-I and Group-II were treated by a dedicated cardiac-obstetric team...
August 3, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/30083036/vitamin-d-deficiency-associated-with-dilated-cardiomyopathy-in-early-infancy-caused-by-maternal-cholestasis
#3
Tomona Omotobara-Yabe, Shuji Kuga, Masahiro Takeguchi, Kenji Ihara
Breast feeding is known to be a major cause of vitamin D deficiency in infants because the content of vitamin D in breast milk is significantly lower than that in formula. We report a case of a 1-mo-old boy who developed hypocalcemic seizures and dilated cardiomyopathy caused by vitamin D deficiency despite being fed a sufficient amount of regular formula. The cause of vitamin D deficiency in this case was maternal vitamin deficiency due to severe hyperemesis and insufficient sunlight exposure, induced mainly by the malabsorption of fat-soluble vitamins caused by maternal cholestasis...
2018: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/30051292/peripartum-cardiomyopathy-an-update
#4
REVIEW
Feriel Azibani, Karen Sliwa
PURPOSE OF REVIEW: Peripartum cardiomyopathy (PPCM) is an idiopathic disorder defined as heart failure occurring in women during the last month of pregnancy and up to 5 months postpartum. In this review, we outline recent reports about the disease pathogenesis and management and highlight the use of diagnosis and prognosis biomarkers. RECENT FINDINGS: Novel data strengthen the implication of endothelial function in PPCM pathogenesis. The first international registry showed that patient presentations were similar globally, with heterogeneity in patient management and outcome...
July 26, 2018: Current Heart Failure Reports
https://www.readbyqxmd.com/read/29997384/severe-course-of-peripartum-cardiomyopathy-and-subsequent-recovery-in-a-patient-with-a-novel-ttn-gene-truncating-mutation
#5
Karolina E Kryczka, Zofia Dzielińska, Maria Franaszczyk, Izabela Wojtkowska, Jan Henzel, Mateusz Śpiewak, Janina Stępińska, Zofia T Bilińska, Rafał Płoski, Marcin Demkow
BACKGROUND Peripartum cardiomyopathy (PPCM) is a potentially life-threatening, pregnancy-associated cause of heart failure affecting previously healthy women. Recent research suggests a possible role of 16-kDa prolactin in promoting cardiomyocyte damage. However, the genetic predisposition is not well recognized. CASE REPORT We report the case of a 25-year-old woman with a severe course of PPCM with left ventricle ejection fraction of 25-30%, complicated by ventricular arrhythmia and postpartum thyroiditis...
July 12, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29973095/is-there-a-role-for-cardiac-magnetic-resonance-imaging-during-pregnancy
#6
Matthew Romagano, Adetola Louis-Jacques, Joanne Quinones, Ronald Freudenberger, Laurie Fleming, John Smulian, Matthew Martinez
PURPOSE: To assess the role of cardiac magnetic resonance imaging (CMR) for the evaluation and management of women with cardiac disorders in pregnancy and postpartum. METHODS: Retrospective record review of women at a university-affiliated, single institution referred for CMR without contrast due to known or suspected cardiac disorders between January 2010 and December 2015. Medical records, echocardiogram and CMR reports were reviewed. Instances where clinical management was changed based on CMR findings were identified...
July 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29923132/pregnancy-among-survivors-of-childhood-cancer-cardiovascular-considerations
#7
REVIEW
Michael C Honigberg, Amy A Sarma
PURPOSE OF REVIEW: To educate clinicians on cardiovascular considerations and management strategies surrounding pregnancy in childhood cancer survivors. RECENT FINDINGS: With advances in oncologic treatment, growing numbers of childhood cancer survivors are now able to consider pregnancy. A significant proportion of survivors have received cardiotoxic therapy, particularly anthracyclines, and/or chest radiation. Cardiomyopathy is the most common cardiac complication of cancer-directed therapy; pericardial disease, valvular disease, premature coronary artery disease, and conduction abnormalities are other potential sequelae...
June 19, 2018: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29896993/prolonged-veno-arterial-extracorporeal-life-support-for-cardiac-failure
#8
Sabina Pw Guenther, Yasuhiro Shudo, William Hiesinger, Dipanjan Banerjee
OBJECTIVES: In intractable cardiogenic shock, extracorporeal life support frequently is the last treatment option. Outcomes of prolonged veno-arterial extracorporeal life support for cardiac failure are poorly defined. METHODS: We retrospectively analyzed 10 patients (4 females, age = 36 ± 16 years) who underwent prolonged extracorporeal life support (≥7 days) from December 2015 to March 2017 for cardiogenic shock. The primary endpoint was survival to hospital discharge...
August 2018: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29894997/metabolic-syndrome-in-hyperprolactinemia
#9
Marianne Andersen, Dorte Glintborg
The metabolic syndrome (MetS) is a conglomerate of clinical findings that convey into increased morbidity and mortality from type 2 diabetes mellitus (T2D) and cardiovascular disease. Hyperprolactinemia (hyperPRL) is associated with components of MetS, especially during pregnancy. Endogenous levels of sex steroids are high during pregnancy in contrast to untreated or replaced hypogonadism in most patients with a prolactinoma and hypogonadism may confer increased risk of MetS in hyperPRL. Dopamine-D2-agonist therapy can improve MetS in patients with a prolactinoma and lower glucose levels in patients with T2D...
2018: Frontiers of Hormone Research
https://www.readbyqxmd.com/read/29871663/two-potentially-lethal-conditions-of-probable-immune-origin-occurring-in-a-pregnant-woman-a-case-report
#10
H M Senanayake, M Patabendige
BACKGROUND: Thrombotic thrombocytopenic purpura and peripartum cardiomyopathy are potentially lethal complications of pregnancy. We describe a case in which both of these developed in the same patient. The etiologies of both conditions remain uncertain, but they share immune hyperreactivity as a possible cause. CASE PRESENTATION: A 33-year-old Lankan primigravida gave birth at 38 weeks of gestation by cesarean section when she presented with right-sided abdominal pain and a provisional diagnosis of appendicitis...
June 6, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29749620/peripartum-cardiomyopathy-a-systematic-review-of-the-literature
#11
REVIEW
Zain Ul Abideen Asad, Mirwais Maiwand, Fahmi Farah, Tarun W Dasari
Peripartum cardiomyopathy (PPCM) is a rare cause of heart failure. It is defined as cardiomyopathy that develops in the last month of pregnancy or within 5 months of the postpartum period without an identifiable cause. We conducted a systematic review of literature of prospective studies with a focus on echocardiographic and long-term clinical outcomes in PPCM. We searched MEDLINE and Embase up to October 1, 2017. Prospective studies (sample size ≥20) reporting all-cause mortality and follow-up duration of ≥1 year were included...
May 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29747728/management-of-obstructive-sleep-apnea-in-pregnancy
#12
REVIEW
Jennifer E Dominguez, Linda Street, Judette Louis
The spectrum of sleep-disordered breathing (SDB) ranges from mild snoring to obstructive sleep apnea, the most severe form of SDB. Current recommendations are to treat these women with continuous positive airway pressure despite limited data. SDB in early and mid-pregnancy is associated with preeclampsia and gestational diabetes. Pregnant women with a diagnosis of obstructive sleep apnea at delivery were at significantly increased risk of having cardiomyopathy, congestive heart failure, pulmonary embolism, and in-hospital death...
June 2018: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/29699420/analysis-of-preventability-of-hypertensive-disorder-in-pregnancy-related-maternal-death-using-the-nationwide-registration-system-of-maternal-deaths-in-japan
#13
Shinji Katsuragi, Hiroaki Tanaka, Junichi Hasegawa, Masamitsu Nakamura, Naohiro Kanayama, Masahiko Nakata, Takeshi Murakoshi, Jun Yoshimatsu, Kazuhiro Osato, Kayo Tanaka, Akihiko Sekizawa, Isamu Ishiwata, Tomoaki Ikeda
OBJECTIVE: Hypertensive disorder of pregnancy (HDP) is a major cause of maternal death. The goal of this study was to investigate factors associated with maternal death due to HDP. STUDY DESIGN: HDP-related maternal deaths in Japan reported to the Committee of the Ministry of Health, Labor and Welfare from 2010 to 2015 were examined. RESULTS: Out of 47 cases of HDP, 30 were identified as the major cause of maternal death. The median maternal age was 34 years (range 24-45) and the mortality in women aged ≥40 years was seven times higher that than in women aged <34 years...
April 26, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29601327/peripartum-cardiomyopathy-approach-to-management
#14
Sorel Goland, Uri Elkayam
PURPOSE OF REVIEW: To provide recommendations for the diagnosis and management of patients with peripartum cardiomyopathy (PPCM). RECENT FINDINGS: PPCM is pregnancy-associated myocardial disease that occurs during pregnancy or postpartum and is characterized by the development of heart failure due to marked left ventricular (LV) systolic dysfunction. The disease is relatively uncommon, but its incidence is increasing, and it remains an important cause of cardiac-related maternal morbidity and mortality in previously healthy young women...
May 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29578284/long-term-prognosis-subsequent-pregnancy-contraception-and-overall-management-of-peripartum-cardiomyopathy-practical-guidance-paper-from-the-heart-failure-association-of-the-european-society-of-cardiology-study-group-on-peripartum-cardiomyopathy
#15
Karen Sliwa, Mark C Petrie, Denise Hilfiker-Kleiner, Alexandre Mebazaa, Alice Jackson, Mark R Johnson, Peter van der Meer, Amam Mbakwem, Johann Bauersachs
Peripartum cardiomyopathy is an idiopathic cardiomyopathy presenting with heart failure secondary to left ventricular systolic dysfunction towards the end of pregnancy or in the months following delivery, where no other cause for heart failure is identified. Outcome varies from full recovery to residual left ventricular systolic dysfunction and even death. Many women return to their physician to acquire information on their long-term prognosis, to seek medical advice regarding contraception, or when planning a subsequent pregnancy...
June 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29544927/pregnancy-and-newborn-outcomes-in-arrhythmogenic-right-ventricular-cardiomyopathy-dysplasia
#16
E Gandjbakhch, E Varlet, G Duthoit, V Fressart, P Charron, C Himbert, C Maupain, C Bordet, F Hidden-Lucet, J Nizard
INTRODUCTION: The prognosis of pregnancy in patients with Arrhythmogenic Right Ventricular Cardiomyopathy/dysplasia (ARVC/D) is poorly documented. The aim of this study is to assess the cardiac risks during pregnancy and the impact of ARVC/D on fetuses/neonates/children. METHODS: We included all ARVC/D women with a history of pregnancy from the ARVC/D Pitié-Salpêtrière registry. Cardiac and obstetrical events having occurred during pregnancy/delivery/post-partum periods and neonatal data/follow-up were collected...
May 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29530774/anomalous-left-coronary-artery-from-the-pulmonary-artery-masquerading-as-peripartum-cardiomyopathy
#17
Jonathan Frigault, Valérie Lafrenière-Bessi, Jean Perron, Élisabeth Bédard, François Philippon, Paul Poirier, Éric Larose, Frédéric Jacques
Diagnosed with peripartum cardiomyopathy 8 years earlier, a 45-year-old woman had sudden cardiac death. After resuscitation, the patient was diagnosed with an anomalous origin of the left coronary artery from the pulmonary artery and underwent a successful coronary repair. The management of a patient with clinical features of cardiomyopathy is reviewed.
July 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29416222/clinical-course-and-treatment-of-dilated-cardiomyopathy-during-twenty-years-of-follow-up
#18
Edin Begic, Zijo Begic, Nabil Naser
Objective: Demonstration of idiopathic dilated cardiomyopathy with unusual flow, unpredictable clinical picture and complex therapy. Case report: Patient A.P., female, 38 years old, had symptoms of dilated cardiomyopathy (with possible infectious myocarditis in the background) at age 17. After hospitalization for ten months and ten days, while waiting for heart transplantation (with threatening death outcome), without a clearly pronounced threatening arrhythmia, but with a low ejection fraction and a poor general condition, remission occurred...
February 2018: Medical Archives
https://www.readbyqxmd.com/read/29395758/what-s-going-wrong-with-this-postpartum-woman
#19
Bedriye Müge Sönmez, Murat Doğan İşcanlı, Tamer Durdu, İrfan Kala, Nurullah Tarhan, Pınar Uysal
Peripartum cardiomyopathy (PPCM) is a left ventricular systolic dysfunction failure emerges during the antepartum or puerperal period, and can result in maternal death. Reported incidences are increasing and differing globally. Echocardiography is the cornerstone for the diagnosis. The immediate goals in acute management are the stabilization of the hemodynamic state, providing symptomatic relief, and ensuring fetal wellbeing. Emergency physicians should be aware of PPCM at the differential diagnosis of dyspnea in pregnancy related emergencies and play role in early diagnosis...
April 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29339690/the-rationale-and-design-of-the-national-peripartum-cardiomyopathy-registries-in-turkey-the-artemis-i-and-artemis-ii-studies
#20
Meral Kayıkçıoğlu, Lale Tokgözoğlu, Ferit Onur Mutluer, Dilek Ural, Murat Biteker
OBJECTIVE: Peripartum cardiomyopathy (PPCM) is left ventricular (LV) systolic dysfunction with an ejection fraction of ≤45% occurring in the later stages of pregnancy or soon after delivery. Although various risk factors have been identified, the exact cause of the disease is unknown. Unlike most countries in the European region, Turkey has yet to determine the current PPCM burden. A registry for this purpose does not exist. To close this gap, the A RegisTry of pEripartuM cardIomyopathy in Turkish patientS (ARTEMIS-I and ARTEMIS-II), was planned and endorsed by the Turkish Society of Cardiology...
January 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
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