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Juey-Ming Shih, Yao-Ming Shih, Yu-Chen Hou, Man-Hui Pai, Chiu-Li Yeh, Sung-Ling Yeh
This study investigated the effects of a fish oil-based lipid emulsion (FO) on local skeletal muscle and remote renal damage at 72 h post-reperfusion in a murine model of hind limb ischemia-reperfusion (IR) injury. Mice were assigned to 1 sham group and 3 IR groups. The IR groups were treated daily with either saline or FO from 3 days prior to limb ischemia till 3 days after reperfusion. Limb IR was induced by applying a 4.5-oz orthodontic rubber band above the left greater trochanter for 120 min followed by band-released reperfusion for 72 h...
August 13, 2018: Cytokine
Maodian Liu, Long Chen, Yipeng He, Zofia Baumann, Robert P Mason, Huizhong Shen, Chenghao Yu, Wei Zhang, Qianggong Zhang, Xuejun Wang
The global pollutant mercury (Hg), especially as methylmercury (MeHg), threatens human and ecosystem health. But major contributors of MeHg exposure to people in China remain highly debated. We developed the China Mercury Exposure Assessment (CMEA) model, which incorporates human exposure pathways for MeHg and total Hg (THg), the interregional, including international and interprovincial, food trading as well as human physiology to provide a comprehensive system that can evaluate the pathway of Hg forms to human consumers in China...
August 13, 2018: Environment International
Yong-Zhen Zhang, Wei-Chen Wu, Mang Shi, Edward C Holmes
Despite a substantial increase in our knowledge of the biodiversity and evolution of vertebrate RNA viruses, far less is known about the diversity, evolution and origin of RNA viruses across the diverse phylogenetic range of viruses, and particularly in healthy animals that are often only rarely utilized for virological sampling. Fortunately, recent advances in virus discovery using metagenomic approaches are beginning to reveal a multitude of RNA viruses in vertebrates other than birds and mammals. In particular, fish harbor a remarkable array of RNA viruses, including the relatives of important pathogens...
August 13, 2018: Current Opinion in Virology
Mahtab Mohammadi, Nasrollah Mahboobi-Soofiani, Omidvar Farhadian, Pedram Malekpouri
Changes in water temperature and pH levels have substantial adverse effects on aquatic organisms, hence causing physiological constraint on their well-being. To understand the physiological responses of Chondrostoma regium to temperature or pH changes, standard metabolic rate (SMR), maximum metabolic rate (MMR), absolute and factorial aerobic scope (AS&FAS) as well as the specific rate of ammonia excretion (Jamm ) were measured at following temperatures: acute low (3.5-4.5 °C), 24 h low (5.5-6.5 °C), 7 d low (5...
August 10, 2018: Science of the Total Environment
Thomas H Miller, Matteo D Gallidabino, James R MacRae, Stewart F Owen, Nicolas R Bury, Leon P Barron
The application of machine learning has recently gained interest from ecotoxicological fields for its ability to model and predict chemical and/or biological processes, such as the prediction of bioconcentration. However, comparison of different models and the prediction of bioconcentration in invertebrates has not been previously evaluated. A comparison of 24 linear and machine learning models is presented herein for the prediction of bioconcentration in fish and important factors that influenced accumulation identified...
August 10, 2018: Science of the Total Environment
E Prato, F Biandolino, I Parlapiano, S Giandomenico, G Denti, M Calò, L Spada, A Di Leo
Seafood is recognized as a healthy food choice due to high contents of essential nutrients, including polyunsaturated fatty acids (PUFAs) of the n-3 family. However, seafood is often contaminated by toxic compounds, which have adverse effects on human health. The aim of this study was to provide information about the percentage of edible part, condition index and the benefit and risk for human consumers health associated to the consumption of eight bivalve species (Flexopecten glaber, Mimachlamys varia, Modiolus barbatus, Mytilus galloprovincialis, Ostrea edulis, Ruditapes philippinarum, Solen marginatus and Venus verrucosa) of high commercial value, purchased from Taranto local fish markets...
July 31, 2018: Science of the Total Environment
Zhengrui Zhang, Zhenkui Qin
Midkine (Mdk)is a cytokine involved in controlling tissue repair and new tissue development, and regulating inflammation involved in several signaling pathway, such as the mitogen-activated protein kinase (MAPK) and phosphatidyl inositol 3-kinase (PI3K)/AKT pathways. But the role of Mdk in the development of Cynoglossus semilaevis is poorly understood. In this study, the Midkine of C. semilaevis (CsMdk) was cloned, and its spatiotemporal expression pattern and structural characteristics were analyzed. Furthermore, the essential genes related to nervous system development and germ layer formation marker gene were identified by qRT-PCR and in situ hybridization after overexpression the CsMdk via zebrafish model...
August 13, 2018: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
Scott C Cutmore, Thomas H Cribb, Russell Q-Y Yong
Fishes of the elasmobranch superorder Batoidea and the basal teleost superorder Elopomorpha were assessed for blood flukes (Digenea: Aporocotylidae) during a parasitological survey conducted in Moreton Bay, Queensland, Australia. A new blood fluke genus and species, Ogawaia glaucostegi n. gen., n. sp., is described from the Giant shovelnose ray, Glaucostegus typus (Anonymous [Bennett]) (Rhinopristiformes: Glaucostegidae). Ogawaia glaucostegi differs from species of all other aporocotylid genera in the combination of the absence of anterior caeca and oral sucker, having a pronounced distal oesophageal chamber, a strongly coiled testis and a common genital pore...
August 13, 2018: Parasitology International
John Eme, Casey A Mueller, Abigail H Lee, Christopher Melendez, Richard G Manzon, Christopher M Somers, Douglas R Boreham, Joanna Y Wilson
Lake whitefish (Coregonus clupeaformis) utilize overwintering embryonic development (up to 180 days), and such stenothermic, cold-water embryos may be particularly susceptible to thermal shifts. We incubated whitefish embryos in temperature treatments that were constant temperature (2.0 ± 0.1 °C, 5.0 ± 0.1 °C, and 8.0 ± 0.1 °C; mean ± SD) or variable temperature (VT, mean = 5.0 ± 0.3 °C). In the VT, a daily 2 °C temperature change followed a continuous pattern throughout development: 2-4-6-8-6-4-2 °C...
August 13, 2018: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
Bénédicte Mj Merle, Johanna M Colijn, Audrey Cougnard-Grégoire, Alexandra P M de Koning-Backus, Marie-Noëlle Delyfer, Jessica C Kiefte-de Jong, Magda Meester-Smoor, Catherine Féart, Timo Verzijden, Cécilia Samieri, Oscar H Franco, Jean-François Korobelnik, Caroline C W Klaver, Cécile Delcourt
OBJECTIVE: To investigate associations of adherence to the Mediterranean diet (MeDi) with incidence of advanced AMD (the symptomatic form of AMD) in two European population-based prospective cohorts. DESIGN: Prospective cohorts: the Rotterdam Study I (RS-I) and the Alienor Study. PARTICIPANTS: 4 446 participants aged ≥55 years from RS-I (The Netherlands) and 550 French adults aged 73 years or older from Alienor Study with complete ophthalmologic and dietary data were included in the present study...
August 13, 2018: Ophthalmology
Laura Sedra, Jean-Paul Paluzzi, Angela B Lange
In this study, a long neuropeptide F receptor of the blood-feeding hemipteran, Rhodnius prolixus (RhoprNPFR) has been cloned and characterized. Approximately 70% of the RhoprNPFR deduced protein sequence is identical to that of other hemipteran NPFRs. RhoprNPFR has seven highly-conserved transmembrane domains, two cysteine residues in the 2nd and 3rd extracellular loops that likely form a disulfide bond integral for maintaining the structure of the receptor, and a conserved DRY motif after the third transmembrane domain...
2018: PloS One
Yevhen Horokhovatskyi, Mariola A Dietrich, Ievgen Lebeda, Pavlo Fedorov, Marek Rodina, Borys Dzyuba
In many fish species, sperm cryopreservation has deleterious effects and leads to a significant decrease in spermatozoa viability. However, the effect of cryopreservation on sperm cells that survive this process and are still viable is not fully understood. The objective of this study was to compare the viability and proteomes of fresh and cryopreserved sterlet (Acipenser ruthenus) sperm samples before and after live-dead cell separation using Percoll density gradient centrifugation. Both fresh and cryopreserved sperm samples were divided into two groups (with or without application of Percoll separation)...
2018: PloS One
Xiujuan Lei, Xiaoqin Yang, Fangxiang Wu
It is well known that essential proteins play an extremely important role in controlling cellular activities in living organisms. Identifying essential proteins from protein protein interaction (PPI) networks is conducive to the understanding of cellular functions and molecular mechanisms. Hitherto, many essential proteins detection methods have been proposed. Nevertheless, those existing identification methods are not satisfactory because of low efficiency and low sensitivity to noisy data. This paper presents a novel computational approach based on artificial fish swarm optimization for essential proteins prediction in PPI networks (called AFSO_EP)...
August 15, 2018: IEEE/ACM Transactions on Computational Biology and Bioinformatics
Stefan Grigorakis, Kenneth Gregory Drouillard
Diet assimilation efficiencies (AEs) of polychlorinated biphenyls (PCBs) absorbed to microplastics and food were determined in goldfish (Carassius auratus). Microplastics were spiked with 14 environmentally rare PCBs and incorporated into fish pellets previously spiked with a technical PCB mixture (Aroclor 1254). Five diet treatments were created having microplastic contents of 0, 5, 10, 15, 20 and 25% and fed to fish within 24 h of the diet creation. Fish from each treatment were fed a microplastic amended food pellet and PCB AEs were determined by mass balance...
August 16, 2018: Environmental Science & Technology
Yi-Tzu Kuo, Ya-Ting Chao, Wan-Chieh Chen, Ming-Che Shih, Song-Bin Chang
Background and Aims: Orchidaceae is a large plant family, and its extraordinary adaptations may have guaranteed its evolutionary success. Flavonoids are a group of secondary metabolites that mediate plant acclimation to challenge environments. Chalcone synthase (CHS) catalyses the initial step in the flavonoid biosynthetic pathway. This is the first chromosome-level investigation of the CHS gene family in Phalaenopsis aphrodite and was conducted to elucidate if divergence of this gene family is associated with chromosome evolution...
August 2, 2018: Annals of Botany
Anne M R Schrader, Patty M Jansen, Maarten H Vermeer, Johanna K Kleiverda, Joost S P Vermaat, Rein Willemze
Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT) and primary cutaneous follicle center lymphoma (PCFCL) are cutaneous B-cell lymphomas (CBCL) with different clinical characteristics and behavior. PCDLBCL-LT is the most aggressive CBCL with a relatively poor prognosis. In nodal diffuse large B-cell lymphoma (DLBCL), rearrangements of the MYC gene, especially in combination with a second hit in BCL2 and/or BCL6, and double protein expression of MYC and BCL2 (DE) are adverse prognostic factors...
August 14, 2018: American Journal of Surgical Pathology
I V Korobko, M V Shepelev
Atypical RhoV GTPase (Chp/Wrch-2) is a member of the human Rho GTPase family, which belongs to the superfamily of Ras-related small GTPases. The biological functions of RhoV, regulation of its activity, and mechanisms of its action remain largely unexplored. Rho GTPases regulate a wide range of cellular processes by interacting with protein targets called effectors. Several putative RhoV effectors have been identified, including protein kinases of the Pak (p21-activated kinase) family: Pak1, Pak2, Pak4, and Pak6...
July 2018: Molekuliarnaia Biologiia
Conor P Kerley
Growing evidence has emerged about the role of dietary patterns and components in heart failure (HF) incidence and severity. The objective here is to provide a comprehensive summary of the current evidence regarding dietary patterns/components and HF. A comprehensive search of online databases was conducted using multiple relevant keywords to identify relevant human studies. The Dietary Approaches to Stop Hypertension (DASH) and Mediterranean diets have consistently been associated with decreased HF incidence and severity...
August 16, 2018: Nutrition Research Reviews
Vinita Vishwakarma, Balakrishnan Anandkumar
Concrete structures develop biofilms when exposed to various environments. At a certain stage, the microbial films destroy the concrete structures leading to significant deterioration. Culture-dependent techniques give an incomplete picture of the microbial communities on the concrete surface. Culture independent techniques or molecular biological tools pave a new way to analyze microbial communities involved in concrete biodeterioration. This study highlights the need to 'build' a database, for Microbiologically Influenced Concrete Corrosion (MICC) involving microbial groups that are being identified using culture dependent and independent techniques...
August 16, 2018: Environmental Technology
Claudia Kasper, Francois Olivier Hebert, Nadia Aubin-Horth, Barbara Taborsky
Juveniles of the cooperatively-breeding cichlid fish Neolamprologus pulcher either consistently provide help in form of alloparental egg care ('cleaners') or consistently abstain from helping ('non-cleaners'). These phenotypes are not based on heritable genetic differences. Instead they arise during ontogeny, which should lead to differences in brain structure or physiology, a currently untested prediction. We compared brain gene expression profiles of cleaners and non-cleaners in two experimental conditions, a helping opportunity and a control condition...
August 15, 2018: Molecular Ecology
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