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Pediatric Obstructive Sleep Apnea

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https://www.readbyqxmd.com/read/28541508/self-efficacy-and-short-term-adherence-to-continuous-positive-airway-pressure-treatment-in-children
#1
Melissa S Xanthopoulos, Ji Young Kim, Michael Blechner, Ming-Yu Chang, Mary Kate Menello, Christina Brown, Edward Matthews, Terri E Weaver, Justine Shults, Carole L Marcus
Study Objectives: Infants, children and adolescents are increasingly being prescribed continuous positive airway pressure (CPAP) for treatment of obstructive sleep apnea (OSAS), yet adherence is often poor. The purpose of this study was to examine the relationship between caregiver and patient-reported health cognitions about CPAP prior to starting CPAP, and CPAP adherence at one month. We hypothesized that greater caregiver-reported self-efficacy would be positively associated with CPAP adherence in children...
May 24, 2017: Sleep
https://www.readbyqxmd.com/read/28522103/urinary-biomarkers-and-obstructive-sleep-apnea-in-patients-with-down-syndrome
#2
Ibrahim Elsharkawi, David Gozal, Eric A Macklin, Lauren Voelz, Gil Weintraub, Brian G Skotko
STUDY OBJECTIVES: The study aimed to compare urinary biomarkers in patients with Down syndrome (DS) with and without obstructive sleep apnea (OSA) to those of age- and sex-matched neurotypically developing healthy controls (HC). We further investigated whether we could predict OSA in patients with DS using these biomarkers. METHODS: Urine samples were collected from 58 patients with DS the night before or the morning after their scheduled overnight polysomnogram or both, of whom 47 could be age- and sex-matched to a sample of 43 HC...
June 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28490038/pediatric-sleep-disordered-breathing-an-update-on-diagnostic-testing
#3
Brian McGrath, Jerrold Lerman
PURPOSE OF REVIEW: Recent advances in diagnostic testing for obstructive sleep apnea in children have refined the standard tests while identifying several new tools that hold promise to radically change how we diagnose sleep apnea. RECENT FINDINGS: Studies have demonstrated that the polysomnogram may be modified to permit home assessment of sleep disturbed breathing in children to ensure more widespread access to the test. Alternately, questionnaires, nocturnal oximetry, and diagnostic urinary biomarkers have shown great promise as both sensitive and specific tools to diagnose sleep apnea in children as well as track the severity of the disease...
June 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28479786/study-of-sleep-disorders-among-young-children-using-hindi-translated-and-validated-version-of-pediatric-sleep-questionnaire
#4
Ravi Gupta, Ramjan Ali, Sunanda Verma, Kriti Joshi, Mohan Dhyani, Kanchan Bhasin, Neha Bhasin, Jatin Goyal
OBJECTIVE: The objective of this study is to assess the prevalence of sleep disorders among children aging between 4 and 9 years using Hindi version of Pediatric Sleep Questionnaire (PSQ). METHODS: This study had two parts first, translation and validation of PSQ into Hindi language, and second, assessment of the prevalence of sleep disorders using PSQ Hindi version. Hindi PSQ was distributed in randomly chosen primary schools in a semi-urban area. The children were requested to get them filled by their parents...
April 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28474375/angiopoietin-2-and-soluble-tie-2-receptor-plasma-levels-in-children-with-obstructive-sleep-apnea-and-obesity
#5
David Gozal, Abdelnaby Khalyfa, Zhuanghong Qiao, Dale L Smith, Mona F Philby, Dorit Koren, Leila Kheirandish-Gozal
OBJECTIVE: Obstructive sleep apnea (OSA) is a prevalent condition, especially in children with obesity, and is associated with increased risk for metabolic syndrome (MetS). Angiopoietins have been identified as potential biomarkers of endothelial dysfunction and MetS. In adults, angiopoietin-2 (Ang-2) and its soluble receptor (sTie-2) are associated with diabetes, hypertension, and obesity and could be increased in children with OSA and obesity, particularly those with evidence of cardiometabolic alterations...
June 2017: Obesity
https://www.readbyqxmd.com/read/28468151/tracheal-cartilaginous-sleeve-in-syndromic-craniosynostosis-an-underrecognized-source-of-significant-morbidity-and-mortality
#6
Brent B Pickrell, Jesse D Meaike, Karina T Cañadas, Binoy M Chandy, Edward P Buchanan
Tracheal cartilaginous sleeve (TCS) is a rare and previously unrecognized source of morbidity and mortality in patients with certain craniosynostosis syndromes. There is a paucity of reporting on this airway anomaly, and the true incidence of TCS is largely unknown. The purpose of this study was to investigate the incidence of TCS among patients with syndromic craniosynostosis at our institution. Patients with syndromic craniosynostosis who underwent direct bronchoscopy and laryngoscopy were evaluated retrospectively by pediatric otolaryngologists for the presence of TCS and associated anomalies...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28454600/sleep-and-breathing-the-first-night-after-adenotonsillectomy-in-obese-children-with-obstructive-sleep-apnea
#7
Aliva De, Temima Waltuch, Nathan J Gonik, Ngoc Nguyen-Famulare, Hiren Muzumdar, John P Bent, Carmen R Isasi, Sanghun Sin, Raanan Arens
STUDY OBJECTIVES: There are few studies measuring postoperative respiratory complications in obese children with obstructive sleep apnea (OSA) undergoing adenotonsillectomy (AT). These complications are further compounded by perioperative medications. Our objective was to study obese children with OSA for their respiratory characteristics and sleep architecture on the night of AT. METHODS: This was a prospective study at a tertiary pediatric hospital between January 2009-February 2012...
April 25, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28452099/poor-sleep-quality-has-an-adverse-effect-on-childhood-asthma-control-and-lung-function-measures
#8
Youn Ho Sheen, Sun Hee Choi, Sun Jung Jang, Ji Hyeon Baek, Hye Mi Jee, Mi Ae Kim, Kyu Young Chae, Man Yong Han
BACKGROUND: It is unclear as to whether sleep respiratory breathing disorder (SRBD) is a risk factor for uncontrolled asthma in children. We investigated whether the SRBD may have an adverse effect on levels of childhood asthma control and lung function measures. METHODS: This is a cross-sectional study of 220 children with well-controlled (n=108), partly-controlled (n=92), and uncontrolled asthma (n=20) according to the GINA guideline. SRBD was assessed by using the Pediatric Sleep Questionnaire (PSQ)...
April 28, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28443988/efficacy-of-minimally-invasive-tonsil-surgery-for-treatment-of-obstructive-sleep-apnea-hypopnea-syndrome-in-children
#9
X-Q Zhang, H Wang, J Zhou, P Zeng, Y Zhao, Y Zhang, C Liu, L-Q Jiang, Y-J Lan
This study aimed to investigate the efficacy of minimally invasive tonsil surgery for the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) in children. Tonsil ablation or turbinate reduction was performed on 49 pediatric patients with OSAHS by minimally invasive tonsil surgery. In order to evaluate the efficacy of surgery, a comparison was conducted between pre-operation and post-operation data in terms of the symptoms, signs and polysomnography test. Total effectiveness rate of the surgery was 83...
April 20, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28439197/clinical-and-polysomnographic-features-of-children-evaluated-with-polysomnography-in-pediatric-sleep-laboratory
#10
Hatice Ezgi Barış, Yasemin Gökdemir, Ela Erdem Eralp, Nilay Baş İkizoğlu, Fazilet Karakoç, Bülent Karadağ, Refika Ersu
AIM: Sleep disordered breathing is a common problem in childhood that encompasses a spectrum of disorders extending from primary snoring to obstructive sleep apnea. This study aims to investigate the results of children undergoing evaluation with polysomnography in the sleep laboratory of a tertiary care hospital. MATERIAL AND METHODS: Demographic and clinical features as well as sleep associated symptoms, scores of pediatric sleep questionnaire and Pittsburgh sleep quality index and polysomnography results are retrospectively evaluated...
March 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28417683/tracheostomy-for-severe-pediatric-obstructive-sleep-apnea-indications-and-outcomes
#11
Christopher J Rizzi, Julian D Amin, Amal Isaiah, Tulio A Valdez, Anita Jeyakumar, Suzanne E Smart, Kevin D Pereira
Objectives (1) To describe characteristics of pediatric patients undergoing tracheostomy for obstructive sleep apnea (OSA). (2) To highlight perioperative events and outcomes of the procedure. Study Design Case series with chart review. Setting Four tertiary care academic children's hospitals. Subjects and Methods Twenty-nine children aged <18 years from January 1, 2010, to December 31, 2015, who underwent tracheostomy for severe OSA, defined as an apnea-hypopnea index (AHI) >10, were included in the study...
April 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28410811/long-term-non-invasive-ventilation-therapies-in-children-a-scoping-review
#12
REVIEW
Maria L Castro-Codesal, Kristie Dehaan, Robin Featherstone, Prabhjot K Bedi, Carmen Martinez Carrasco, Sherri L Katz, Elaine Y Chan, Glenda N Bendiak, Fernanda R Almeida, Deborah L Olmstead, Rochelle Young, Vicki Woolf, Karen A Waters, Colin Sullivan, Lisa Hartling, Joanna E MacLean
Long-term non-invasive ventilation (NIV) is a common modality of breathing support used for a range of sleep and respiratory disorders. The aim of this scoping review was to provide a summary of the literature relevant to long-term NIV use in children. We used systematic methodology to identify 11,581 studies with final inclusion of 289. We identified 76 terms referring to NIV; the most common term was NIV (22%). Study design characteristics were most often single center (84%), observational (63%), and retrospective (54%)...
March 2, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28378061/tongue-surgeries-for-pediatric-obstructive-sleep-apnea-a-systematic-review-and-meta-analysis
#13
REVIEW
Macario Camacho, Michael W Noller, Soroush Zaghi, Lauren K Reckley, Camilo Fernandez-Salvador, Erika Ho, Brandyn Dunn, Dylan Chan
OBJECTIVES: To evaluate the international literature for studies reporting outcomes for obstructive sleep apnea (OSA) in children undergoing isolated tongue surgeries. METHODS: Two authors searched from inception through November 14, 2016 in four databases including PubMed/MEDLINE. RESULTS: 351 studies were screened. Eleven studies (116 children) met criteria. Most children were syndromic and had craniofacial disorders, co-morbidities, or other serious medical issues...
April 4, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28364508/financial-analysis-of-an-intensive-pediatric-continuous-positive-airway-pressure-program
#14
E Brooks Riley, Evan S Fieldston, Melissa S Xanthopoulos, Suzanne E Beck, Mary Kate Menello, Edward Matthews, Carole L Marcus
Study Objectives: Continuous positive airway pressure (CPAP) is effective in treating obstructive sleep apnea in children, but adherence to therapy is low. Our center created an intensive program that aimed to improve adherence. Our objective was to estimate the program's efficacy, cost, revenue and break-even point in a generalizable manner relative to a standard approach. Methods: The intensive program included device consignment, behavioral psychology counseling, and follow-up telephone calls...
February 1, 2017: Sleep
https://www.readbyqxmd.com/read/28364431/validation-of-the-sonomat-against-psg-and-quantitative-measurement-of-partial-upper-airway-obstruction-in-children-with-sleep-disordered-breathing
#15
Mark B Norman, Sonia M Pithers, Arthur Y Teng, Karen A Waters, Colin E Sullivan
Study Objectives: To validate the Sonomat against polysomnography (PSG) metrics in children and to objectively measure snoring and stertor to produce a quantitative indicator of partial upper airway obstruction that accurately reflects the pathology of pediatric sleep-disordered breathing (SDB). Methods: Simultaneous PSG and Sonomat recordings were performed in 76 children (46 male, age 5.8 ± 2.8, BMI = 18.5 ± 3.8 kg/m2). Sleep time, individual respiratory events and the apnea/hypopnea index (AHI) were compared...
March 1, 2017: Sleep
https://www.readbyqxmd.com/read/28364411/urinary-cysteinyl-leukotriene-e4-level-and-therapeutic-response-to-montelukast-in-children-with-mild-obstructive-sleep-apnea
#16
Kanokkarn Sunkonkit, Suchada Sritippayawan, Montida Veeravikrom, Jitladda Deerojanawong, Nuanchan Prapphal
BACKGROUND: Antileukotriene has been used for alleviating disease severity in children with adenotonsillar hypertrophy (ATH) and mild obstructive sleep apnea (OSA). Previous study showed the relationship between urinary cysteinyl leukotriene E₄ (uLTE₄) level and therapeutic response to montelukast in asthmatic adults. However, this relationship has never been investigated in pediatric OSA. OBJECTIVES: To determine the relationship between uLTE₄ level and therapeutic response to montelukast in children with ATH and mild OSA...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28356177/automated-screening-of-children-with-obstructive-sleep-apnea-using-nocturnal-oximetry-an-alternative-to-respiratory-polygraphy-in-unattended-settings
#17
Daniel Álvarez, María L Alonso-Álvarez, Gonzalo C Gutiérrez-Tobal, Andrea Crespo, Leila Kheirandish-Gozal, Roberto Hornero, David Gozal, Joaquín Terán-Santos, Félix Del Campo
STUDY OBJECTIVES: Nocturnal oximetry has become known as a simple, readily available, and potentially useful diagnostic tool of childhood obstructive sleep apnea (OSA). However, at-home respiratory polygraphy (HRP) remains the preferred alternative to polysomnography (PSG) in unattended settings. The aim of this study was twofold: (1) to design and assess a novel methodology for pediatric OSA screening based on automated analysis of at-home oxyhemoglobin saturation (SpO2), and (2) to compare its diagnostic performance with HRP...
May 15, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28350680/airway-and-feeding-outcomes-of-mandibular-distraction-tongue-lip-adhesion-and-conservative-management-in-pierre-robin-sequence-a-prospective-study
#18
Ibrahim Khansa, Courtney Hall, Lauren L Madhoun, Mark Splaingard, Adriane Baylis, Richard E Kirschner, Gregory D Pearson
BACKGROUND: Pierre Robin sequence is characterized by mandibular retrognathia and glossoptosis resulting in airway obstruction and feeding difficulties. When conservative management fails, mandibular distraction osteogenesis or tongue-lip adhesion may be required to avoid tracheostomy. The authors' goal was to prospectively evaluate the airway and feeding outcomes of their comprehensive approach to Pierre Robin sequence, which includes conservative management, mandibular distraction osteogenesis, and tongue-lip adhesion...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28323671/codeine-and-opioid-metabolism-implications-and-alternatives-for-pediatric-pain-management
#19
Vidya Chidambaran, Senthilkumar Sadhasivam, Mohamed Mahmoud
PURPOSE OF REVIEW: Use of perioperative opioids for surgical pain management of children presents clinical challenges because of concerns of serious adverse effects including life-threatening respiratory depression. This is especially true for children with history of obstructive sleep apnea. This review will explore current knowledge of clinically relevant factors and genetic polymorphisms that affect opioid metabolism and postoperative outcomes in children. RECENT FINDINGS: Within the past several years, an increasing number of case reports have illustrated clinically important respiratory depression, anoxic brain injuries and even death among children receiving appropriate weight-based dosages of codeine and other opioids for analgesia at home setting particularly following tonsillectomy...
June 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28320866/adenotonsillotomy-versus-adenotonsillectomy-in-pediatric-obstructive-sleep-apnea-an-rct
#20
Anna Borgström, Pia Nerfeldt, Danielle Friberg
BACKGROUND: Adenotonsillectomy (ATE) is a well-established and effective treatment of pediatric obstructive sleep apnea (OSA). In recent years, a more conservative method, adenotonsillotomy (ATT), has gained popularity because it is associated with less postoperative morbidity. Yet no previous randomized study has compared these 2 methods regarding their effectiveness in treating pediatric OSA in terms of polysomnographic data, which was the primary aim of this study. The hypothesis was that ATT is noninferior to ATE after 1 year...
March 20, 2017: Pediatrics
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