keyword
https://read.qxmd.com/read/38655418/split-doses-versus-whole-dose-bowel-preparation-using-polyethylene-glycol-for-colonoscopy-a-multicentric-prospective-lebanese-randomized-trial-between-2021-and-2023
#21
JOURNAL ARTICLE
Blaybel Sara, Hammoud Ghinwa, Mourda Layla, Hallal Mahmoud, Khalil Ali, Mckey Remy
BACKGROUND AND AIMS: Bowel preparation is considered as major obstacle before colonoscopy, and it is often reported as the most feared part of the procedure. The aim of this study is to determine the difference in efficacy between a split dose of PEG and the previous day regimen in cleaning the colon, using Boston bowel preparation scale. In addition, also to evaluate patient satisfaction regarding the modality of preparation. METHODS: The study included 200 hospitalized patients undergoing colonoscopy at Beirut hospitals between 2021 and 2023...
April 2024: Health Science Reports
https://read.qxmd.com/read/38655381/recombinant-pth-infusion-in-a-child-with-sanjad-sakati-syndrome-refractory-to-conventional-therapy
#22
Ibrahim Bali, Reem Al Khalifah
Hypoparathyroidism is the most common endocrinological feature in children with Sanjad-Sakati syndrome. Treatment includes active vitamin D and calcium supplementation. Here, we report a case of a newborn with Sanjad-Sakati syndrome who had severe hypocalcemia since birth who responded to PTH subcutaneous pump infusion. The child was born at 35 weeks with hypocalcemia since the first day of life. The standard medical treatment proved ineffective for the newborn, necessitating the administration of unusually high doses of oral and IV calcium and vitamin D analogue for a 2 months...
April 2024: JCEM Case Rep
https://read.qxmd.com/read/38655276/reliability-of-renal-point-of-care-ultrasound-pocus-performed-by-pediatric-postgraduates-to-diagnose-hydronephrosis-in-infants
#23
JOURNAL ARTICLE
Eun Jung Cheon, Jung Min Yoon
PURPOSE: Point-of-care ultrasound (POCUS) has gained prominence in a variety of medical specialties due to advances in ultrasound technology. POCUS has not been fully integrated into pediatric residency training programs despite its widespread use and proven benefits. At our institution, renal POCUS is performed by pediatric residents for the evaluation of hydronephrosis, which is the main pathology for which ultrasound is used in the clinical practice of pediatric nephrology. This study was conducted to evaluate the quality of renal POCUS performed by pediatric residents in infants...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38655258/effect-of-high-dose-spirulina-supplementation-on-hospitalized-adults-with-covid-19-a-randomized-controlled-trial
#24
RANDOMIZED CONTROLLED TRIAL
Mohammad Reza Aghasadeghi, Mohammad Ali Zaheri Birgani, Saeedreza Jamalimoghadamsiyahkali, Hadiseh Hosamirudsari, Ali Moradi, Majid Jafari-Sabet, Nooshin Sadigh, Pooneh Rahimi, Rezvan Tavakoli, Mojtaba Hamidi-Fard, Golnaz Bahramali, Zohal Parmoon, Sina Arjmand Hashjin, Ghasem Mirzajani, Reza Kouhkheil, Somayeh Roshangaran, Samineh Khalaf, Mohammad Khademi Nadoushan, Ghazaleh Gholamiyan Yousef Abad, Nima Shahryarpour, Mohammad Izadi, Abolfazl Zendedel, Shayesteh Jahanfar, Omid Dadras, SeyedAhmad SeyedAlinaghi, Daniel Hackett
OBJECTIVE: Spirulina ( arthrospira platensis ) is a cyanobacterium proven to have anti-inflammatory, antiviral, and antioxidant effects. However, the effect of high-dose Spirulina supplementation on hospitalized adults with COVID-19 is currently unclear. This study aimed to evaluate the efficacy and safety of high-dose Spirulina platensis for SARS-CoV-2 infection. STUDY DESIGN: We conducted a randomized, controlled, open-label trial involving 189 patients with COVID-19 who were randomly assigned in a 1:1 ratio to an experimental group that received 15...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38655247/epidemiological-characteristics-of-human-infections-with-avian-influenza-a-h5n6-virus-china-and-laos-a-multiple-case-descriptive-analysis-february-2014-june-2023
#25
JOURNAL ARTICLE
Simran Sandhu, Christina Ferrante, Aaron MacCosham, Nicole Atchessi, Christina Bancej
BACKGROUND: The first human infection with highly pathogenic avian influenza A(H5N6) virus was reported in 2014. From then until June 30, 2023, 85 human cases with confirmed A(H5N6) infection have been reported worldwide. OBJECTIVE: To address the present gap in knowledge of the overall epidemiology of human A(H5N6) infections, the epidemiological characteristics of human infection with A(H5N6) in China from February 2014 to June 2023 are described. METHODS: Considering the severity of human infections with A(H5N6) virus (case fatality rate: 39%), the increased frequency of case reports from 2021 to present day, and lack of comprehensive epidemiologic analysis of all cases, we conducted a multiple-case descriptive analysis and a literature review to create an epidemiologic profile of reported human cases...
January 1, 2024: Canada Communicable Disease Report
https://read.qxmd.com/read/38655069/machine-learning-based-predictive-modeling-of-readmissions-following-extracorporeal-membrane-oxygenation-hospitalizations
#26
JOURNAL ARTICLE
Jeffrey Balian, Sara Sakowitz, Arjun Verma, Amulya Vadlakonda, Emma Cruz, Konmal Ali, Peyman Benharash
BACKGROUND: Despite increasing utilization and survival benefit over the last decade, extracorporeal membrane oxygenation (ECMO) remains resource-intensive with significant complications and rehospitalization risk. We thus utilized machine learning (ML) to develop prediction models for 90-day nonelective readmission following ECMO. METHODS: All adult patients receiving ECMO who survived index hospitalization were tabulated from the 2016-2020 Nationwide Readmissions Database...
June 2024: Surgery open science
https://read.qxmd.com/read/38655023/cohort-study-of-patients-with-advanced-cancer-outcomes-associated-with-duration-of-antibiotic-therapy-for-non-ventilator-hospital-acquired-pneumonia
#27
JOURNAL ARTICLE
Seohyuk Lee, Jemma Benson, Avi Cohen, Vincent Quagliarello, Manisha Juthani-Mehta, Rupak Datta
In this single-center observational study of 118 older adults with advanced cancer who developed non-ventilator hospital-acquired pneumonia, prolonged antibiotic durations (8-14 and ≥15 vs ≤7 d) were not associated with reduced adjusted odds of 90-day all-cause readmission or death. These data may inform antimicrobial stewardship efforts in palliative care settings.
2024: Antimicrob Steward Healthc Epidemiol
https://read.qxmd.com/read/38654950/a-troublesome-complication-of-hydatid-cysts-intra-abdominal-rupture-a-10-year-study-from-a-high-volume-center
#28
JOURNAL ARTICLE
Hüseyin Yönder, Mehmet Sait Berhuni, Hasan Elkan, Abdullah Özgönül, Ahmet Bertan, Vedat Kaplan, Ali Uzunköy
BACKGROUND: Hydatid cyst is a parasitic infection, often caused by Echinococcus granulosus . Although it is classified as a benign disease, cyst ruptures in the abdomen can be fatal. Ruptures occur spontaneously or after trauma. We aimed to report data from patients who underwent emergency surgery due to spontaneous intra-abdominal hydatid cyst rupture. METHODS: Upon a retrospective review of the records at Department of General Surgery, Faculty of Medicine, Harran University, Şanlıurfa, Turkey, we found that 34 cases were operated on due to hydatid cyst rupture between January 2012 and October 2022...
2024: Iranian Journal of Parasitology
https://read.qxmd.com/read/38654948/isolation-of-schistosoma-haematobium-in-bronchoalveolar-lavage-in-an-immunocompromised-individual-a-case-report
#29
Shailesh Bhanudas Meshram, Hiral Gulab Ramnani, Spandana Chaudhury
Schistosomiasis is a parasitic disease caused by trematodes (body flukes), affecting millions worldwide. However, its pulmonary manifestations are rare. We report a rare case of a 51-year-old People Living with HIV male, managed in a tertiary care hospital in west India in May 2023, vegetable vendor who was admitted with complaints of dysphagia, odynophagia, fever and chest pain for 3 days, cough and breathlessness for 1 month. Chest x-ray and CT scan were suggestive of hypodense fluid collection with rim enhancement along right lateral and posterior aspect of thoracic esophagus...
2024: Iranian Journal of Parasitology
https://read.qxmd.com/read/38654944/visceral-leishmaniasis-vl-clinical-presentation-laboratory-findings-treatment-options-and-outcome
#30
JOURNAL ARTICLE
Mahmoud Khodabandeh, Elham Moradian, Maedeh Sarvari, Mahsa Soti Khiabani
BACKGROUND: Black disease, also known as visceral leishmaniasis (VL), is a parasitic illness caused by various Leishmania species. The risk of morbidity and mortality increases with delayed diagnosis and treatment. Early VL diagnosis and fast appropriate treatment are critical issues in endemic areas. METHODS: This study was a retrospective cross-sectional study to investigate the diagnostic and therapeutic course of patients admitted with the diagnosis of VL in the Children's Medical Center (CMC) Hospital, Tehran, Iran...
2024: Iranian Journal of Parasitology
https://read.qxmd.com/read/38654888/active-amphetamine-abuse-in-total-hip-arthroplasty-carries-increased-risk-for-postoperative-surgical-and-medical-complications
#31
JOURNAL ARTICLE
Mackenzie Kelly, Thomas Huff, Kathryn Schabel, Jung Yoo, Elizabeth Lieberman, Ryland Kagan
BACKGROUND: The impact of amphetamine abuse on total hip arthroplasty (THA) outcomes has yet to be studied. As the rates of methamphetamine abuse continue to rise, understanding the risk profile of this population is imperative. This study aims to determine the risk of major surgical and medical complications for those with amphetamine abuse undergoing THA, with the hypothesis that amphetamine abuse carries increased risk. METHODS: A retrospective review was performed with all-claims data files of a large national database querying International Classification of Disease, tenth revision, procedure codes identifying 333,038 primary THA, and 1027 with active amphetamine abuse...
June 2024: Arthroplasty Today
https://read.qxmd.com/read/38654860/the-association-between-different-anesthetic-techniques-and-outcomes-in-patients-undergoing-transfemoral-aortic-valve-replacement
#32
JOURNAL ARTICLE
Ahmad Abuzaid, Ibrahim AbdelAal, Ahmed Galal
BACKGROUND: There is an increasing number of patients undergoing transfemoral aortic valve replacement (TAVR) with sedation. There is limited data assessing the efficacy and safety of the different types of sedative drugs. The objective was to compare two sedation techniques with regard to the need for vasoactive support, respiratory support, rate of conversion to general anesthesia (GA), common perioperative morbidities, intensive care unit (ICU) stay, and in-hospital mortality. METHODS: A retrospective chart review study conducted among patients who underwent TAVR at a specialized cardiac center between January 2016 and December 2019...
2024: Saudi Journal of Anaesthesia
https://read.qxmd.com/read/38654842/translation-and-validation-of-the-sinus-and-nasal-quality-of-life-surgery-survey-in-serbian
#33
JOURNAL ARTICLE
Nevena Jovicic, Masa Petrovic, Bojana Salovic, Aleksandar Matejic, Ana Tomic, Nina Milanovic, Teja Scepanovic, Nabil Alhayek, Ivan Soldatovic
OBJECTIVE: The aim of this study was to translate the Sinus and Nasal Quality of Life Surgery Survey into the Serbian language to evaluate the test-retest reliability and validity. STUDY DESIGN: The study included 49 consecutive patients between 12 and 18 years old with rhinologic symptoms. Patients were given a paper survey to complete along with a link to complete the online survey within the same day. SETTING: The study was conducted at the University Children's Hospital Clinic for Pulmonology and Allergology between January 2023 and March 2023...
2024: OTO Open
https://read.qxmd.com/read/38654840/abdominal-physical-examinations-in-early-stages-benefit-critically-ill-patients-without-primary-gastrointestinal-diseases-a-retrospective-cohort-study
#34
JOURNAL ARTICLE
Xiao Cui, Yu Shi, Xinlei He, Mingyuan Zhang, Hua Zhang, Jianhong Yang, Yuxin Leng
BACKGROUND: Gastrointestinal (GI) function is critical for patients in intensive care units (ICUs). Whether and how much critically ill patients without GI primary diseases benefit from abdominal physical examinations remains unknown. No evidence from big data supports its possible additive value in outcome prediction. METHODS: We performed a big data analysis to confirm the value of abdominal physical examinations in ICU patients without GI primary diseases. Patients were selected from the Medical Information Mart for Intensive Care (MIMIC)-IV database and classified into two groups depending on whether they received abdominal palpation and auscultation...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38654819/plasmapheresis-in-post-covid-19-myelitis-a-case-report
#35
JOURNAL ARTICLE
Witoon Mitarnun, Lisa Kongngern, Praewa Tantisungvarakoon, Theerapun Boonsayomphu, Nithit Tianchetsada, Tanluck Potchanapong
BACKGROUND: Previous studies have delineated different neurological manifestations associated with coronavirus disease 2019 (COVID-19). Myelitis is identified as a rare neurological complication resulting from a COVID-19 infection. Limited information is available regarding the treatment of patients experiencing this condition. CASE REPORT: This report extracts data from the medical record of a post-COVID-19 myelitis patient at Buriram Hospital and follows up prospectively on the patient's symptoms after treatment...
2024: Qatar Medical Journal
https://read.qxmd.com/read/38654816/surgical-treatment-of-multiple-magnet-ingestion-by-children-a-single-center-experience-from-china
#36
JOURNAL ARTICLE
Chen Zhang, Xiao-Wen Zhang, Shao-Mei Liu, Ke-Hua Huang, Zi-Min Chen
BACKGROUND: The incidence of magnet ingestion in children has escalated concurrent with the rise in popularity of magnetic playthings, bearing the capacity to induce substantial morbidity. AIM: The objective of this study was to encapsulate our accumulated expertise in handling pediatric cases featuring multiple magnetic foreign bodies within the gastrointestinal tract sometimes necessitating surgical intervention, as well as to formulate a clinical management algorithm...
2024: Qatar Medical Journal
https://read.qxmd.com/read/38654784/correlation-of-platelet-parameters-with-the-severity-of-thrombocytopenia-in-dengue-fever-in-children-aged-less-than-18-years-at-a-tertiary-care-centre-a-cross-sectional-study
#37
JOURNAL ARTICLE
Rachana A Sontakke, Nisha R Aglave, Himanshu Dua
Introduction Dengue is a tropical viral disease caused by dengue virus with varied severity ranging from dengue fever to dengue shock syndrome. In dengue infection, there is thrombocytopenia with platelet activation. According to various proposed theories, activation of platelets during thrombocytopenia leads to changes in platelet parameters like mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), and platelet index (PI). So, this study was conducted to correlate platelet parameters with the severity of thrombocytopenia in children with dengue fever at a tertiary care hospital...
March 2024: Curēus
https://read.qxmd.com/read/38654771/the-relationship-between-blood-culture-c-reactive-protein-and-neonatal-sepsis-a-cross-sectional-study
#38
JOURNAL ARTICLE
Amjed A Ali, Mustafa Ahmed, Sufian K Noor, Leena Mustafa, Waad Ibrahim, Mohamed ElAmin, Hatim M Badri, Hatim A Natto, Wahaj A Khan, Ahmed A Osman
Background Sepsis is one of the most common causes of morbidity and mortality in newborns. Diagnosis of neonatal sepsis may be difficult because the clinical presentations are often nonspecific. Neonatal sepsis may have an early onset (zero to three days) or a late onset (four days or later). Onset is most rapid in premature neonates. In this study, we aimed to assess the correlation between positive cultures, high C-reactive protein (CRP) levels, and the diagnosis of neonatal sepsis. Methodology This descriptive, prospective, cross-sectional study was undertaken over four months starting from December 15, 2019, to April 15, 2020, in Atbara Teaching Hospital, Sudan...
March 2024: Curēus
https://read.qxmd.com/read/38654729/reduced-prevalence-of-drug-related-problems-in-psychiatric-inpatients-after-implementation-of-a-pharmacist-supported-computerized-physician-order-entry-system-a-retrospective-cohort-study
#39
JOURNAL ARTICLE
Katharina Wien, Julia Thern, Anika Neubert, Britta-Lena Matthiessen, Stefan Borgwardt
INTRODUCTION: In 2021, a computerized physician order entry (CPOE) system with an integrated clinical decision support system (CDSS) was implemented at a tertiary care center for the treatment of mental health conditions in Lübeck, Germany. To date, no study has been reported on the types and prevalence of drug-related problems (DRPs) before and after CPOE implementation in a psychiatric inpatient setting. The aim of this retrospective before-and-after cohort study was to investigate whether the implementation of a CPOE system with CDSS accompanied by the introduction of regular medication plausibility checks by a pharmacist led to a decrease of DRPs during hospitalization and unsolved DRPs at discharge in psychiatric inpatients...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38654668/monocyte-response-to-sars-cov-2-protein-orf8-is-associated-with-severe-covid-19-infection-in-patients-with-chronic-lymphocytic-leukemia
#40
JOURNAL ARTICLE
Gordon J Ruan, Xiaosheng Wu, Kimberly A Gwin, Michelle K Manske, Jithma P Abeykoon, Vaishali Bhardwaj, Taylor L Witter, Matthew J Schellenberg, Kari G Rabe, Neil E Kay, Sameer A Parikh, Thomas E Witzig
The open reading frame 8 (ORF8) protein, encoded by the SARS-CoV-2 virus after infection, stimulates monocytes/macrophages to produce pro-inflammatory cytokines. We hypothesized that a positive ex vivo monocyte response to ORF8 protein pre-COVID-19 would be associated with subsequent severe COVID-19. We tested ORF8 ex vivo on peripheral blood mononuclear cells (PBMCs) from 26 anonymous healthy blood donors and measured intracellular cytokine/chemokine levels in monocytes by flow cytometry. The % monocytes staining positive in the sample and change in mean fluorescence intensity (ΔMFI) after ORF8 were used to calculate the adjusted MFI for each cytokine...
April 24, 2024: Haematologica
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