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https://www.readbyqxmd.com/read/28212586/effects-of-resistance-band-exercise-on-vascular-activity-and-fitness-in-older-adults
#1
Mark F Smith, Mistrelle Ellmore, Geoff Middleton, Paul M Murgatroyd, Thomas I Gee
This study investigated the effects of a low to moderately intense resistance-band exercise intervention on cutaneous microvascular function in an older population. 18 sedentary healthy participants (age: 58±5) were assessed for their upper and lower-limb endothelial cutaneous vascular conductance using laser Doppler fluximetry with endothelial-dependent (80 μl acetylcholine chloride), and -independent vasodilation (80 μl sodium nitroprusside). In addition, participants underwent a range of functional assessments (cardiopulmonary fitness, strength, flexibility), and completed a perceived quality of life questionnaire...
February 17, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28212584/hyaluronic-acid-serum-albumin-conjugate-based-nanoparticles-for-targeted-cancer-therapy
#2
Ravit Edelman, Yehuda G Assaraf, Inna Levitzky, Tal Shahar, Yoav D Livney
Multiple carcinomas including breast, ovarian, colon, lung and stomach cancer, overexpress the hyaluronic acid (HA) receptor, CD44. Overexpression of CD44 contributes to key cancer processes including tumor invasion, metastasis, recurrence, and chemoresistance. Herein, we devised novel targeted nanoparticles (NPs) for delivery of anticancer chemotherapeutics, comprised of self-assembling Maillard reaction-based conjugates of HA and bovine serum albumin (BSA). HA served as the hydrophilic block, and as the ligand for actively targeting cancer cells overexpressing CD44...
February 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28212579/suicidal-ideation-among-chinese-cancer-inpatients-of-general-hospitals-prevalence-and-correlates
#3
Bao-Liang Zhong, Si-Heng Li, Shu-Yan Lv, Shun-Li Tian, Zhi-Dong Liu, Xu-Bin Li, Hong-Qing Zhuang, Ran Tao, Wei Zhang, Chuan-Jun Zhuo
Cancer patients are at high risk for suicide, particularly when they are informed about the cancer diagnosis or hospitalized for cancer treatment. Therefore, oncology healthcare settings such as large general hospitals in China, may represent an ideal setting to identify and treat suicidality in cancer patients. However, the clinical epidemiology of suicidality of Chinese cancer patients remains largely unknown. This study examined the prevalence and correlates of suicidal ideation among Chinese cancer inpatients of large general hospitals...
February 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28212542/two-stage-genome-wide-association-study-identifies-a-novel-susceptibility-locus-associated-with-melanoma
#4
Katherine J Ransohoff, Wenting Wu, Hyunje G Cho, Harvind C Chahal, Yuan Lin, Hong-Ji Dai, Christopher I Amos, Jeffrey E Lee, Jean Y Tang, David A Hinds, Jiali Han, Qingyi Wei, Kavita Y Sarin
Genome-wide association studies have identified 21 susceptibility loci associated with melanoma. These loci implicate genes affecting pigmentation, nevus count, telomere maintenance, and DNA repair in melanoma risk. Here, we report the results of a two-stage genome-wide association study of melanoma. The stage 1 discovery phase consisted of 4,842 self-reported melanoma cases and 286,565 controls of European ancestry from the 23andMe research cohort and the stage 2 replication phase consisted of 1,804 melanoma cases and 1,026 controls from the University of Texas M...
February 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28212526/can-you-feel-the-body-that-you-see-on-the-relationship-between-interoceptive-accuracy-and-body-image
#5
Giorgia Zamariola, Flavia Cardini, Emanuel Mian, Andrea Serino, Manos Tsakiris
Interoception and exteroception for body signals are two different ways of perceiving the self: the first from within, the second from outside. We investigated the relationship between Interoceptive Accuracy (IAcc) and external perception of the body and we tested if seeing the body from an external perspective can affect IAcc. Fifty-two healthy female subjects performed a standard heartbeat perception task to assess the IAcc, before and after the Body Image Revealer (BIR), which is a body perception task designed to assess the different aspects of body-image...
February 14, 2017: Body Image
https://www.readbyqxmd.com/read/28212481/-workplace-bullying-during-specialty-training-in-a-pediatric-hospital-in-mexico-a-little-noticed-phenomenon
#6
Ana Carolina Sepúlveda-Vildósola, Alma Rebeca Mota-Nova, Germán Enrique Fajardo-Dolci, L Isabel Reyes-Lagunes
BACKGROUND: Workplace bullying (WB) is a hostile or intimidating behavior that is practiced against workers and has a negative impact on health, job performance, and the learning process. The objective was to research WB magnitude and its associated factors in Mexico. METHODS: Mixed method study. A survey was designed and administered to all the residents in a pediatric hospital in Mexico who agreed to participate. The survey was divided in two sections: a) resident self-reported events of workplace bullying and associated factors, b) situations and factors of abuse were interrogated in a targeted manner...
2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28212464/oxytocin-reduces-ethanol-self-administration-in-mice
#7
Courtney E King, William C Griffin, Lauryn N Luderman, Malcolm M Kates, Jacqueline F McGinty, Howard C Becker
BACKGROUND: Excessive ethanol consumption remains an important health concern and effective treatments are lacking. The central oxytocin system has emerged as a potentially important therapeutic target for alcohol and drug addiction. These studies tested the hypothesis that oxytocin reduces ethanol consumption. METHODS: Male C57BL/6J mice were given access to ethanol (20% v/v) using a model of binge-like drinking ("drinking-in-the-dark") that also included the use of lickometer circuits to evaluate the temporal pattern of intake as well as 2-bottle choice drinking in the home cage...
February 17, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28212449/energy-intake-and-energy-expenditure-of-pre-professional-female-contemporary-dancers
#8
Meghan A Brown, Glyn Howatson, Edel Quin, Emma Redding, Emma J Stevenson
Many athletes in aesthetic and weight dependent sports are at risk of energy imbalance. However little is known about the exercise and eating behaviours of highly trained dance populations. This investigation sought to determine the energy intake and energy expenditure of pre-professional female contemporary dancers. Twenty-five female contemporary dance students completed the study. Over a 7-day period, including five week days (with scheduled dance training at a conservatoire) and two weekend days (with no scheduled dance training at the conservatoire), energy intake (self-reported weighed food diary and 24 h dietary recall) and expenditure (tri-axial accelerometry) were recorded...
2017: PloS One
https://www.readbyqxmd.com/read/28212440/emergent-inequality-and-self-organized-social-classes-in-a-network-of-power-and-frustration
#9
Benoit Mahault, Avadh Saxena, Cristiano Nisoli
We propose a simple agent-based model on a network to conceptualize the allocation of limited wealth among more abundant expectations at the interplay of power, frustration, and initiative. Concepts imported from the statistical physics of frustrated systems in and out of equilibrium allow us to compare subjective measures of frustration and satisfaction to collective measures of fairness in wealth distribution, such as the Lorenz curve and the Gini index. We find that a completely libertarian, law-of-the-jungle setting, where every agent can acquire wealth from or lose wealth to anybody else invariably leads to a complete polarization of the distribution of wealth vs...
2017: PloS One
https://www.readbyqxmd.com/read/28212421/a-low-cost-dac-bist-structure-using-a-resistor-loop
#10
Jaewon Jang, Heetae Kim, Sungho Kang
This paper proposes a new DAC BIST (digital-to-analog converter built-in self-test) structure using a resistor loop known as a DDEM ADC (deterministic dynamic element matching analog-to-digital converter). Methods for both switch reduction and switch effect reduction are proposed for solving problems related to area overhead and accuracy of the conventional DAC BIST. The proposed BIST modifies the length of each resistor in the resistor loop via a merging operation and reduces the number of switches and resistors...
2017: PloS One
https://www.readbyqxmd.com/read/28212400/surveys-of-public-knowledge-and-attitudes-with-regard-to-antibiotics-in-poland-did-the-european-antibiotic-awareness-day-campaigns-change-attitudes
#11
Beata Mazińska, Izabela Strużycka, Waleria Hryniewicz
BACKGROUND: Antimicrobial resistance is a global public health problem. Monitoring the level of knowledge regarding antibiotics is a part of the European Union Community strategy against antimicrobial resistance. OBJECTIVE: To assess knowledge by the general public in Poland regarding antibiotics, AMR, and the impact of the European Antibiotic Awareness Day campaigns. METHODS: The repeated cross-sectional study was developed and carried out among the general public in Poland (in 5 waves between 2009 and 2011, embracing a total of 5004 respondents)...
2017: PloS One
https://www.readbyqxmd.com/read/28212391/an-empirical-examination-of-the-factor-structure-of-compassion
#12
Jenny Gu, Kate Cavanagh, Ruth Baer, Clara Strauss
Compassion has long been regarded as a core part of our humanity by contemplative traditions, and in recent years, it has received growing research interest. Following a recent review of existing conceptualisations, compassion has been defined as consisting of the following five elements: 1) recognising suffering, 2) understanding the universality of suffering in human experience, 3) feeling moved by the person suffering and emotionally connecting with their distress, 4) tolerating uncomfortable feelings aroused (e...
2017: PloS One
https://www.readbyqxmd.com/read/28212340/prospective-prediction-of-juvenile-homicide-attempted-homicide-among-early-onset-juvenile-offenders
#13
Michael T Baglivio, Kevin T Wolff
While homicide perpetrated by juveniles is a relatively rare occurrence, between 2010 and 2014, approximately 7%-8% of all murders involved a juvenile offender. Unfortunately, few studies have prospectively examined the predictors of homicide offending, with none examining first-time murder among a sample of adjudicated male and female youth. The current study employed data on 5908 juvenile offenders (70% male, 45% Black) first arrested at the age of 12 or younger to prospectively examine predictors of an arrest for homicide/attempted homicide by the age of 18...
February 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28212339/adamantane-in-drug-delivery-systems-and-surface-recognition
#14
REVIEW
Adela Štimac, Marina Šekutor, Kata Mlinarić-Majerski, Leo Frkanec, Ruža Frkanec
The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins, and dendrimers based on or incorporating adamantane derivatives. Our recent concept of adamantane as an anchor in the lipid bilayer of liposomes has promising applications in the field of targeted drug delivery and surface recognition. The results reported here encourage the development of novel adamantane-based structures and self-assembled supramolecular systems for basic chemical investigations as well as for biomedical application...
February 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28212279/do-mothers-benefit-from-a-child-focused-cognitive-behavioral-treatment-cbt-for-childhood-functional-abdominal-pain-a-randomized-controlled-pilot-trial
#15
Claudia Calvano, Martina Groß, Petra Warschburger
While the efficacy of cognitive-behavioral treatment (CBT) approaches for childhood functional abdominal pain (FAP) is well-established for child outcomes, only a few studies have reported on parent-specific outcomes. This randomized controlled pilot trial analyzed effects of a group CBT on maternal variables (i.e., pain-related behavior, worries and self-efficacy, as well as general psychosocial strain). Methods: The sample constituted of 15 mothers in the intervention group (IG) and 14 mothers in the waitlist control group (WLC)...
February 15, 2017: Children
https://www.readbyqxmd.com/read/28212196/prison-nursing-formation-of-a-stable-professional-identity
#16
Khurshid Choudhry, David Armstrong, Alexandru Dregan
AIM: The aim of this study was to analyze how working within prison environments can influence the self-identity and professional identity of nurses. BACKGROUND: The prison environment can be a difficult environment for nurses to deliver care within, with nurses having to carry out activities that seem to go against their professional role, while at the same time providing care to prisoners who have greater health needs than the general population. There is a lack of theoretical consideration of how prison nurses carry out their role in the face of such challenges...
January 2017: Journal of Forensic Nursing
https://www.readbyqxmd.com/read/28212174/categorizing-and-assessing-negative-symptoms
#17
Paola Bucci, Silvana Galderisi
PURPOSE OF REVIEW: To provide a review on studies published in the last year relevant to the categorization and assessment of negative symptoms. RECENT FINDINGS: Recent research supported the validity of the 'deficit/non-deficit schizophrenia' categorization. Few studies confirmed the validity of the category 'persistent negative symptoms', whereas no recent study explored the validity of the category 'predominant negative symptoms'. The two-factor structure of the negative dimension is supported by studies reporting different correlates for the two subdomains: diminished expression and avolition/apathy...
February 15, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28212171/ability-based-emotional-intelligence-in-schizophrenia
#18
Beatrice Frajo-Apor, Alex Hofer
PURPOSE OF REVIEW: As one part of social cognition, emotional intelligence is a controversially discussed construct. Although well founded critique on the conceptualization of emotional intelligence has emerged over the last years, studies about emotional intelligence - especially the ability-based approach by Mayer and Salovey - can persistently be found in schizophrenia research. RECENT FINDINGS: Studies published between October 2015 and October 2016 were included in this review...
February 15, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28212132/hydrocarbon-enema-an-unusual-cause-of-chemical-burn
#19
Justin Mygatt, Mustafa Amani, Patrick Ng, Brian Benson, Jeremy Pamplin, Leopoldo Cancio
Hydrocarbons are a wide-ranging group of flammable chemicals and are often used in suicide attempts either by ingestion or as accelerant in self-immolation. In this case study, we present a 37-year-old female who suffered 6% TBSA partial-thickness burns to her perineum and buttocks, which she claims resulted from diarrhea after ingesting a bottle of lighter fluid. The patient underwent decontamination and medical treatment for her burns and during her inpatient stay, it became apparent that the burns were more likely sustained from an intentional rectal administration of lighter fluid...
February 13, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28212131/psychometric-properties-of-a-new-instrument-for-assessing-irrational-thoughts-in-burn-victims-scale-of-irrational-thoughts-after-burn-injuries
#20
Zahra Zare, Homayoun Sadeghi-Bazargani, Fatemeh Ranjbar, Diana Stark Ekman, Mostafa Farahbakhsh, Hemmat Maghsoudi, Robert Ekman, Farideh Nasiri
The objective of this study was to develop and evaluate a scale for assessing irrational thoughts among burned patients. The present study was mixed (qualitative-methodologic) which was performed in several stages such as investigating similar or related scales, interviewing with patients and psychologists. Content validity was calculated by modified KAPPA basis on relevance and clarity. The reliability of the scale was measured using internal consistency and the test-retest method. To determine the construct validity, exploratory factor analysis approach using maximum likelihood extraction with varimax rotation was conducted...
February 9, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
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