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https://www.readbyqxmd.com/read/30511213/lower-urinary-tract-symptoms-treatment-constraints-assessment-luts-tca-a-new-tool-for-a-global-evaluation-of-neurogenic-bladder-treatments
#1
Nicolas Turmel, Pierre Lévy, Claire Hentzen, Camille Chesnel, Audrey Charlanes, Samer Sheikh-Ismael, Gérard Amarenco, Philippe Manceau
OBJECTIVES: To develop a new tool to assess constraints due to urinary treatments in neurological patients. MATERIALS AND METHODS: A prospective, monocentric study has been conducted from January to May 2017. Out-patients (multiple sclerosis, spinal cord injury, Parkinson disease) were included in a referral center if they had LUTS treatment for at least 3 months. To validate psychometric properties, we conducted a literature review, qualitative interviews, and discussion with a panel of six experts...
December 4, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/30499226/bladder-management-experiences-among-people-living-with-neurologic-disease-a-systematic-review-and-meta-synthesis-of-qualitative-research
#2
Blayne Welk, Patrick McGarry, Michael Kennelly, Jeremy Myers
AIM: To systematically review the qualitative literature on neurogenic bladder management to better understand the relevant psychosocial issues. METHODS: We used two reviewers to systematically review EMBASE, CINAHL, and PsycINFO for qualitative studies that included a neurogenic bladder patient population and were relevant to bladder management. We used a meta-ethnography technique to summarize and synthesize the data. RESULTS: We found 13 studies that were relevant...
November 29, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/30489193/earlier-decompression-8-hours-results-in-better-neurological-and-functional-outcome-after-traumatic-thoracolumbar-spinal-cord-injury
#3
Christof Wutte, Barbara Klein, Johannes Becker, Orpheus Mach, Stephanie Panzer, Martin Strowitzki, Doris Maier, Lukas Grassner
The optimal timing of surgical intervention following spinal cord injury (SCI) remains under debate. Recent studies indicate a potential neurological and functional benefit of early surgery (< 8 hours) after cervical SCI. For thoracolumbar SCI syndromes, fewer studies exist. Bladder and bowel dysfunction are highly relevant for these patients and impair their quality of life. Hence, we performed a retrospective study on patients with thoracolumbar SCI who were operated at our institution and who met inclusion as well as exclusion criteria (n=58 patients)...
November 29, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/30484975/-about-the-indications-to-urodynamic-studies-and-to-a-prior-antibioprophylaxy
#4
Lionel A Micol, Arnas Rakauskas, Brigitte Schurch
In this review article, we refer to recent publications dealing with the indication to pressure-volume and pressure-flow studies using cystometry as well as the indication for antibioprophylaxis prior to these examinations. We conclude that despite various indications these examinations must be reserved for complex cases after exhaustive preliminary evaluation. Moreover, in case of complex urinary incontinence or neurogenic bladder videocystomanometry is recommended for a correct and complete diagnosis. In addition, antibiotic prophylaxis is no longer considered as necessary before these examinations, including for neurological patients...
November 28, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/30473954/an-overview-of-the-pathology-and-emerging-treatment-approaches-for-interstitial-cystitis-bladder-pain-syndrome
#5
REVIEW
Asad Ali, Nouman Safdar Ali, Muhammad Bilal Malik, Zohaib Sayyed, Malik Qistas Ahmad
Our article will discuss bladder pain syndrome (BPS), which is the presence of chronic suprapubic pain to bladder filling accompanied by other urinary symptoms, such as frequency, urgency, discomfort with filling, and relief with emptying of the bladder in the absence of infections or other pathology. It is mostly seen in females and occurs in 0.06%-30% of the population. Some of the proposed mechanisms causing BPS include damage to the bladder lining, a problem manifesting in the pelvic musculature, endocrine, neurological, allergic, autoimmune system, and inflammatory system; however, a definite cause has not been yet identified...
September 17, 2018: Curēus
https://www.readbyqxmd.com/read/30467135/protocol-for-a-phase-ii-open-label-exploratory-study-investigating-the-efficacy-of-fesoterodine-for-treatment-of-adult-patients-with-spinal-cord-injury-suffering-from-neurogenic-detrusor-overactivity-for-amelioration-of-autonomic-dysreflexia
#6
Matthias Walter, Andrea L Ramirez, Amanda Hx Lee, Daniel Rapoport, Alex Kavanagh, Andrei V Krassioukov
INTRODUCTION: Managing and preventing risk factors associated with cardiovascular and cerebrovascular impairment is well studied in able-bodied individuals. However, individuals with spinal cord injury (SCI) at or above the spinal segment T6 are prone to experience autonomic dysreflexia (AD) but also to suffer from neurogenic detrusor overactivity (NDO). Treatment of NDO would not only improve lower urinary tract function but could also reduce the severity and frequency of life-threatening episodes of AD...
November 21, 2018: BMJ Open
https://www.readbyqxmd.com/read/30451783/a-classification-system-for-spinal-cord-compression-and-its-association-with-neurological-deficit-in-spinal-epidural-abscess
#7
Akash A Shah, Huiliang Yang, Mitchel B Harris, Joseph H Schwab
STUDY DESIGN: This was a retrospective case-control study. OBJECTIVE: We aim to describe a novel 5-point grading system to determine the degree and severity of spinal cord compression secondary to a spinal epidural abscess (SEA). Secondarily, we aim to correlate the degree of compression with clinical presentation and outcomes. SUMMARY OF BACKGROUND DATA: Mechanical compression plays an important role in the pathophysiology of neurological dysfunction in SEA...
November 16, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/30428857/rare-case-of-neglected-large-sacral-chordoma-in-a-young-female-treated-by-wide-en-bloc-resection-and-sacrectomy
#8
Zi Hao Phang, Xue Yi Saw, Noreen Fadzlina Binti Mat Nor, Zolqarnain Bin Ahmad, Sa'adon Bin Ibrahim
BACKGROUND: Sacral chordoma is a locally aggressive malignant tumour originating from ectopic notochordal cells. The natural history of sacral chordoma is a slow growing tumour arising at the midline of the lower sacrum that can invade the sacrum and progressively increase in size expanding cranially and anteriorly. Metastasis is very rare even when the tumour is large. Sacral chordoma affects males more than females and is more commonly found in middle age and elderly patients. CASE PRESENTATION: A 25 years old female had neglected an extremely large midline sacral mass for 2 years...
November 14, 2018: BMC Cancer
https://www.readbyqxmd.com/read/30397007/comparison-of-efficacy-and-safety-between-electroacupuncture-at-four-sacral-points-and-conventional-electroacupuncture-for-the-treatment-of-urinary-incontinence-after-stroke-study-protocol-for-a-randomised-controlled-trial
#9
Shan Chen, Siyou Wang, Lihua Xuan, Hanti Lu, Zhikai Hu, Chao Zhang, Huifang Zhang
INTRODUCTION: Electroacupuncture at 'four sacral points', also known as electrical pudendal nerve stimulation therapy, combines the advantages of pudendal nerve neuromodulation and the technique of deep insertion of long acupuncture needles. It has been used to treat stress urinary incontinence, female urgency-frequency syndrome, idiopathic urgency urinary incontinence and neurological bladders in previous studies. Here, we describe the protocol for a randomised controlled trial for evaluation of the efficacy and safety of electroacupuncture at 'four sacral points' for the management of urinary incontinence after stroke...
November 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/30374372/-blunt-abdominal-trauma-causing-acute-pancreatitis-presentation-of-the-case-study
#10
Youssef Khaoula, Jawhar Mokni, Aloui Feten, Beizig Ameni, Maksoudi Chedly
Acute pancreatitis is a serious disease having a guarded prognosis. Its etiology involves either bladder or alcohol. Traumatic origin is extremely rare and it is often associated with other intra-abdominal lesions. We here report the case of a 56-year old man with a history of psychiatric disorders for which he was under therapy with neuroleptics and of left nephrotomy. He presented, after a stair fall occurred 3 days before, with occlusive syndrome. Clinical examination showed normal respiratory hemodynamic and neurological status as well as epigastric tenderness...
2018: Pan African Medical Journal
https://www.readbyqxmd.com/read/30369491/-a-case-of-retro-odontoid-pseudotumor-in-a-very-elderly-individual
#11
Toru Yoshiura, Terushige Toyooka, Yohei Otsuka, Takashi Fujii, Takashi Matsumoto, Kousuke Kumagai, Kazuya Fujii, Satoshi Tomura, Arata Tomiyama, Naoki Otani, Kojiro Wada, Kentaro Mori
Retro-odontoid pseudotumors are mainly caused by aging or rheumatoid arthritis. We treated a very elderly patient with retro-odontoid pseudotumor. A 92-year-old man was admitted with the chief complaints of difficulty walking and progressive numbness in the right upper and lower extremities. Neurological examination revealed muscle weakness and exaggerated tendon reflexes of the right upper and lower extremities, and disturbance in skilled motor activities of the fingers, bilaterally. He had no bladder or rectal disturbances...
October 2018: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/30350478/wwox-the-fra16d-gene-a-target-of-and-a-contributor-to-genomic-instability
#12
REVIEW
Tabish Hussain, Bin Liu, Morgan S Shrock, Terence Williams, C Marcelo Aldaz
WWOX is one of the largest human genes spanning over 1.11 Mbp in length at chr16q23.1-q23.2 and containing FRA16D, the second most common chromosomal fragile site (CFS). FRA16D is a hotspot of genomic instability, prone to breakage and for causing germline and somatic copy number variants (CNVs). Consequentially WWOX is frequent target for deletions in cancer. Esophageal, stomach, colon, bladder, ovarian and uterine cancers are those most commonly affected by WWOX deep focal deletions. WWOX deletions significantly correlate with various clinicopathological features in esophageal carcinoma...
October 23, 2018: Genes, Chromosomes & Cancer
https://www.readbyqxmd.com/read/30347525/factors-affecting-early-and-1-year-motor-recovery-following-lumbar-microdiscectomy-in-patients-with-lumbar-disc-herniation-a-prospective-cohort-review
#13
Vibhu Krishnan Viswanathan, Rajasekaran Shanmuganathan, Siddharth Narasimhan Aiyer, Rishi Kanna, Ajoy Prasad Shetty
Study Design: Prospective cohort study. Purpose: The study was aimed at evaluating clinicoradiological factors affecting recovery of neurological deficits in cases of lumbar disc herniation (LDH) treated by lumbar microdiscectomy. Overview of Literature: The majority of the available literature on neurological recovery following neurodeficit is limited to retrospective series. The literature is currently limited regarding variables that can help predict the recovery of neurodeficits following LDH...
October 24, 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/30346310/current-concepts-central-cord-syndrome
#14
Sohaib Z Hashmi, Angelo Marra, Louis G Jenis, Alpesh A Patel
Central cord syndrome (CCS) represents a clinical phenomenon characterized by disproportionately greater motor impairment of the upper than of the lower extremities, bladder dysfunction. CSS is the most common form of incomplete traumatic spinal cord injury. The initial description of CSS was reported in 1887 secondary to cervical spinal trauma. However, recent literature describes a heterogenous injury patterns including high-energy and low-energy mechanisms and bimodal patient age distributions. Pathophysiology of clinical symptoms and neurological deficits often is affected by preexisting cervical spondylosis...
October 22, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/30346309/depression-increases-the-rates-of-neurological-complications-and-failed-back-surgery-syndrome-in-patients-undergoing-lumbar-spine-surgery
#15
Kyle Schoell, Christopher Wang, Anthony D'Oro, Patrick Heindel, Larry Lee, Jeffrey C Wang, Zorica Buser
STUDY DESIGN: This was a retrospective database study. OBJECTIVE: The aim of this study was to use a large sample to accurately determine risk factors and rates of neurological complications in patients undergoing commonly performed lumbar spine surgeries. SUMMARY OF BACKGROUND DATA: Damage to neurological structures and failed back surgery syndrome (FBSS) are among the most feared complications of lumbar spine surgery. Despite the large impact on quality of life these complications have, reported rates of neurological complications vary immensely, ranging from 0...
October 22, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/30340910/pla2g6-associated-neurodegeneration-new-insights-into-brain-abnormalities-and-disease-progression
#16
Alejandra Darling, Sergio Aguilera-Albesa, Cristina Aisha Tello, Mercedes Serrano, Miguel Tomás, Rafael Camino-León, Joaquín Fernández-Ramos, Adriano Jiménez-Escrig, Pilar Poó, Mar O'Callaghan, Carlos Ortez, Andrés Nascimento, Ramón Candau Fernández Mesaque, Marcos Madruga, Luisa Arrabal, Susana Roldan, Hilario Gómez-Martín, Cristina Garrido, Teresa Temudo, Cristina Jou-Muñoz, Jordi Muchart, Thierry A G M Huisman, Andrea Poretti, Vincenzo Lupo, Carmen Espinós, Belén Pérez-Dueñas
INTRODUCTION: PLA2G6-associated neurodegeneration (PLAN) comprises a continuum of three phenotypes with overlapping clinical and radiologic features. METHODS: Observational clinical study in a cohort of infantile and childhood onset PLAN patients and genetic analysis of the PLA2G6 gene. We analysed chronological evolution in terms of age at onset and disease course through a 66-item questionnaire. We performed qualitative and quantitative assessment of MRI abnormalities and searched for clinical and radiological phenotype and genotype correlations...
October 13, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/30325607/pelvic-floor-electromyography-and-urine-flow-patterns-in-children-with-vesicoureteral-reflux-and-lower-urinary-tract-symptoms
#17
Lida Sharifi-Rad, Seyedeh-Sanam Ladi-Seyedian, Hossein Amirzargar, Abdol-Mohammad Kajbafzadeh
OBJECTIVE: To determine the different urine flow patterns and active pelvic floor electromyography (EMG) during voiding in children with vesicoureteral reflux (VUR) as well as presenting the prevalence of lower urinary tract symptoms in these patients. MATERIALS AND METHODS: We retrospectively reviewed the charts of children diagnosed with VUR after toilet training from Sep 2013 to Jan 2016. 225 anatomically and neurologically normal children were included. The reflux was diagnosed with voiding cystourethrography...
September 25, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/30322260/bladder-recovery-patterns-in-patients-with-complete-cauda-equina-syndrome-a-single-center-study
#18
Ashok Pedabelle Reddy, Rajat Mahajan, Tarush Rustagi, Harvinder Singh Chhabra
Study Design: Retrospective case series. Purpose: Cauda equina syndrome (CES) is associated with etiologies such as lumbar disc herniation (LDH) and lumbar canal stenosis (LCS). CES has a prevalence of 2% among patients with LDH and exhibits variable outcomes, even with early surgery. Few studies have explored the factors influencing the prognosis in terms of bladder function. Therefore, we aimed to assess the factors contributing to bladder recovery and propose a simplified bladder recovery classification...
October 16, 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/30315796/impact-of-isolated-cerebral-perfusion-technique-for-aortic-arch-aneurysm-repair-in-elderly-patients
#19
Keiichiro Kasama, Keiji Uchida, Norihisa Karube, Shigeo Takebayashi, Kiyotaka Imoto, Munetaka Masuda
BACKGROUND: In aortic surgery, a severely atherosclerotic aorta is a known risk factor for perioperative stroke. We adopted a novel procedure of selective cerebral perfusion, named isolated cerebral perfusion (ICP), for the prevention of stroke during aortic arch surgery. METHODS: Between January 2010 and June 2016, 48 patients (mean age, 80 ± 3 years) underwent total aortic arch replacement at our institute, which included nine emergency cases with rupture. ICP was routinely performed for extracorporeal circulation during total arch replacement...
October 10, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/30310640/thoracic-spinal-cord-injury-without-radiologic-abnormality-in-a-pediatric-patient-case-report
#20
Juan Iaconis Campbell, Federico Coppola, Emilio Volpe, Eduardo Salas Lopez
Spinal Cord Injury Without Radiologic Abnormality (SCIWORA) accounts for up to 19% of spinal cord related lesions in pediatric population, mostly comprising the cervical spine. A 2-year-old patient is presented, who suffered a motor-vehicle accident. After being admitted, neither X-Ray nor spinal TC scan showed any structural abnormalities. Neurological examination showed complete sensory and motor loss under T7 as well as bladder and bowel dysfunction. Magnetic resonance imaging (MRI) showed spinal cord lesion extending from T7 to T10...
October 2018: Journal of Surgical Case Reports
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