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NT-Pro-BNP

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https://www.readbyqxmd.com/read/29785232/effects-of-fasudil-on-patients-with-pulmonary-hypertension-associated-with-left-ventricular-heart-failure-with-preserved-ejection-fraction-a-prospective-intervention-study
#1
Xiang Zhang, Xueming Zhang, Saihua Wang, Jun Luo, Zhihong Zhao, Changzhu Zheng, Jieyan Shen
Background: Pulmonary hypertension due to left ventricular heart failure with preserved ejection fraction (PH-HFpEF) is an increasingly medical problem. The aim of the study was to evaluate the clinical efficacy of fasudil on PH-HFpEF elderly patients and to figure out the subtype of PH-HFpEF which may be the therapeutic object of fasudil. Method: 58 PH-HFpEF elderly patients were enrolled. Patients were diagnosed with passive pulmonary hypertension (PPH) or reactive pulmonary hypertension (RPH) by right heart catheterization and all receiving Rho kinase inhibitor fasudil for 2 weeks...
2018: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/29762842/the-role-of-commonly-used-clinical-indicators-in-the-diagnosis-of-acute-heart-failure
#2
X-L Wang, J-M Lei, Y Yuan, L Feng, Y Ning, Y-F Liu
OBJECTIVE: Acute heart failure (AHF) is one of the most commonly seen clinical cases, with a high rate of re-hospitalization and mortality. AHF can be divided into two categories based on the systolic function of the left ventricle, which are heart failure with reduced ejection fraction (HFREF) and heart failure with preserved ejection fraction (HFPEF). Pathogenesis and treatment of the two are quite different. In this article we attempted to explore the value of combined use of clinical and laboratory indicators in the differential diagnosis of AHFREF and AHFPEF...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29744629/cost-effectiveness-of-b-type-natriuretic-peptide-guided-care-in-patients-with-heart-failure-a-systematic-review
#3
REVIEW
Abdosaleh Jafari, Aziz Rezapour, Marjan Hajahmadi
Measuring the level of B-type natriuretic peptide (BNP), as a guide to pharmacotherapy, can increase the survival of patients with heart failure. This study is aimed at systematically reviewing the studies conducted on the cost-effectiveness of BNP-guided care in patients with heart failure. Using the systematic review method, we reviewed the published studies on the cost-effectiveness of BNP-guided care in patients with heart failure during the years 2004 to 2017. The results showed that all studies clearly stated the time horizon of the study and included direct medical costs in their analysis...
May 10, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29716708/the-effect-of-percutaneous-coronary-revascularization-on-plasma-n-terminal-pro-b-type-natriuretic-peptide-levels-in-stable-coronary-artery-disease
#4
Amit Gupta, Jahangir Rashid Beig, Nisar A Tramboo, Dil Afroze, Imran Hafeez, Hilal A Rather
BACKGROUND: This study was conducted to assess the effect of percutaneous coronary revascularization (PCR) on plasma NT-proBNP concentration in patients with chronic stable angina (CSA). METHODS: This prospective open label interventional study included 22 patients with moderate to severe CSA, normal left ventricular (LV) systolic functions and critical (>90%) proximal stenosis in one of the three major epicardial coronary arteries. After stabilization of medications for 8 weeks, resting supine plasma NT-proBNP levels were measured and patients underwent PCR of the involved vessels...
March 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29696164/the-design-and-rationale-of-the-beijing-vascular-disease-patients-evaluation-study-best-study
#5
Huan Liu, Jinbo Liu, Hongwei Zhao, Lihong Li, Guangyun Shang, Yingyan Zhou, Hongyu Wang
Aims: Arteriosclerosis and arterial stiffness increasing are the basic pathophysiological changes of vascular-related diseases, and also the predictor factors of future cardiovascular events. Plasma biomarkers such as glucose, lipids, Homocysteine (Hcy), N-terminal pro-brain natriuretic peptide (NT-proBNP) have been shown to be involved the development of arteriosclerosis. The present study is a prospective observational and follow-up study of the characteristics of subclinical vascular disease detected by non-invasive methods that can predict progression of clinical overt vascular events in a Chinese population...
September 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29673259/exploring-potential-biomarkers-associated-with-health-related-quality-of-life-in-patients-with-coronary-artery-disease-and-heart-failure
#6
Nijole Kazukauskiene, Julius Burkauskas, Jurate Macijauskiene, Narseta Mickuviene, Julija Brozaitiene
OBJECTIVE: There has been a lack of research examining associations between biomarkers and health-related quality of life (HRQoL) in patients with coronary artery disease and heart failure. In patients with coronary artery disease and heart failure, we aimed to explore potential associations between biomarkers of health such as serum levels of thyroid hormones, N-terminal pro-B-type natriuretic peptide (NT-pro-BNP), inflammatory biomarkers and HRQoL. METHODS: In sum, 482 patients (75% male; mean age 58±10 years) with coronary artery disease and heart failure were evaluated for socio-demographic and clinical coronary artery disease risk factors...
April 1, 2018: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29668337/reduced-longitudinal-cardiac-strain-in-asthma-patients
#7
I Tuleta, N Eckstein, F Aurich, G Nickenig, C Schaefer, D Skowasch, R Schueler
OBJECTIVE: There is limited knowledge about the potential relationship between asthma and heart function. Aim of our present study was to examine if asthma may be associated with manifest or subclinical heart dysfunction. METHODS: 72 allergic mild-to-moderate and severe asthma patients and 20 matched controls were enrolled in the study. Depending on the anti-asthmatic therapy, four subgroups of asthma patients were created: patients under long-acting beta2-agonists (LABA) and inhaled cortisone without oral cortisone treatment with (1a) versus without (1b) additional omalizumab therapy; patients with LABA, inhaled cortisone and omalizumab treatment with (2a) versus without (2b) oral cortisone...
April 18, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29666561/comparison-of-barricor%C3%A2-vs-lithium-heparin-tubes-for-selected-routine-biochemical-analytes-and-evaluation-of-post-centrifugation-stability
#8
Anne Marie Dupuy, Stéphanie Badiou, Delphine Daubin, Anne Sophie Bargnoux, Chloé Magnan, Kadda Klouche, Jean Paul Cristol
Introduction: Obtaining suitable results unaffected by pre- or postanalytical phases is pivotal for clinical chemistry service. We aimed comparison and stability of nine biochemical analytes after centrifugation using Barricor™ plasma tubes with mechanical separator vs standard Vacutainer® lithium heparin tubes. Materials and methods: We collected samples on six healthy volunteers and nine patients from intensive care units into 6 mL plastic Vacutainer® lithium heparin tubes and 5...
June 15, 2018: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/29623136/the-effects-of-continuous-positive-airway-pressure-on-premature-ventricular-contractions-and-ventricular-wall-stress-in-patients-with-heart-failure-and-sleep-apnea
#9
Sabri Seyis, Adnan Kazım Usalan, Ibrahim Rencuzogullari, Özge Kurmuş, Adil Can Gungen
Background: We aimed to investigate the effects of continuous positive airway pressure (CPAP) treatment on electrocardiography (ECG), premature ventricular contraction load on 24-hour Holter recordings, and implantable cardioverter defibrillator (ICD) shocks in patients with obstructive sleep apnea syndrome (OSAS) and heart failure. Methods: Patients with heart failure and ICD and patients with newly diagnosed OSAS were divided into two groups according to CPAP treatment...
2018: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/29595686/risk-factors-and-outcomes-of-sepsis-induced-myocardial-dysfunction-and-stress-induced-cardiomyopathy-in-sepsis-or-septic-shock-a-comparative-retrospective-study
#10
COMPARATIVE STUDY
Han Saem Jeong, Tae Hyub Lee, Cho Hee Bang, Jong-Ho Kim, Soon Jun Hong
While both sepsis-induced myocardial dysfunction (SIMD) and stress-induced cardiomyopathy (SICMP) are common in patients with sepsis, the pathogenesis of the 2 diseases is different, and they require different treatment strategies. Thus, we aimed to investigate risk factors and outcomes between the 2 diseases.This retrospective study enrolled patients diagnosed with sepsis or septic shock, admitted to intensive care unit via emergency department in Korea University Anam Hospital, and who underwent transthoracic echocardiography within the first 24 hours of admission...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29590730/serum-osteoprotegerin-in-patients-with-calcified-aortic-valve-stenosis-in-relation-to-heart-failure
#11
Sandra Makarović, Zorin Makarović, Ines Bilić-Ćurčić, Jasminka Milas-Ahić, Ivan Mihaljević, Maja Franceschi, Tomislav Jukić
The aim of the study was to assess the role of serum osteoprotegerin (OPG) as a biomarker in patients with aortic valve stenosis (AS) in relation to heart failure and symptomatic status. This was a case control study, which included 51 patients with AS and 39 control subjects. At the time of study enrolment, detailed medical history was obtained and all subjects underwent physical examination, chest x-ray and echocardiography. OPG levels were measured in all subjects, and serum N-terminal of the pro b-type natriuretic peptide (NT pro BNP) levels were determined in patients with AS...
December 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29582447/sleep-study-guided-multidisciplinary-therapy-sgmt-for-patients-with-acute-coronary-syndrome-trial-rationale-and-design
#12
Ai-Ping Chua, Chieh-Yang Koo, William Kristanto, Maria Victoria Jane Macalalag Parot, Eugene Siang-Joo Tan, Esther Hui-Ting Koh, Munirah Binte Abd Gani, Pipin Kojodjojo, Tun-Oo Han, Siew-Pang Chan, Jenny Pek-Ching Chong, Christopher Frampton, Arthur Mark Richards, Chi-Hang Lee
BACKGROUND: Obstructive sleep apnea (OSA) is an emerging risk marker for acute coronary syndrome (ACS). This randomized trial aims to determine the effects of Sleep Study-Guided Multidisciplinary Therapy (SGMT) comprising overnight sleep study, continuous positive airway pressure, and behavioral therapy for OSA during the sub-acute phase of ACS. METHODS: We hypothesize that SGMT will reduce (1) the plasma levels of N-terminal pro brain natriuretic peptide (NT-pro BNP) and suppression of tumorigenicity 2 (ST2), (2) the estimated 10-year risk of cardiovascular mortality as measured by the European SCORE algorithm, and (3) the cardiovascular event rate during a 3-year follow-up, compared with standard therapy...
March 26, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29575641/nt-pro-bnp-a-marker-for-worsening-respiratory-status-and-mortality-in-infants-and-young-children-with-pulmonary-hypertension
#13
Shahnawaz M Amdani, Muhammad Umair M Mian, Ron L Thomas, Robert D Ross
AIM: To evaluate predictors of morbidity and mortality in pediatric patients with pulmonary hypertension (PH), laboratory and echocardiographic measures of PH were analyzed. METHODS: A retrospective review of all infants and children < 2 years of age with PH from January 2011 to August 2016 was conducted. Correlations were determined using Spearman's rank correlation coefficients. Differences in characteristics between survivors and nonsurvivors were analyzed and Kaplan-Meier survival curves were generated...
March 25, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/29562571/value-of-three-dimensional-speckle-tracking-imaging-for-predicting-left-ventricular-function-after-non-st-segment-elevation-myocardial-infarction-with-percutaneous-coronary-intervention
#14
Yongjuan Luo, Yujie Liu, Xin Guan, Ying Zhang, Jing Li
BACKGROUND: Percutaneous coronary intervention (PCI) is the recommended treatment for high risk patients with non-ST-segment elevation myocardial infarction (NSTEMI). OBJECTIVE: To investigate the application of three dimensional-speckle tracking imaging (3D-STI) on patients diagnosed with NSTEMI undergoing PCI. METHODS: Forty-four NSTEMI patients and 20 healthy subjects that received basic clinical and laboratory examinations were included in our study...
2018: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29544658/impact-of-internal-and-external-electrical-cardioversion-on-cardiac-specific-enzymes-and-inflammation-in-patients-with-atrial-fibrillation-and-heart-failure
#15
Philipp Stieger, Obaida R Rana, Erol Saygili, Haschmatulla Zazai, Thomas Rauwolf, Conrad Genz, Rajen Bali, Ruediger C Braun-Dullaeus, Samir M Said
BACKGROUND: Implantable cardioverter/defibrillator (ICD) shocks can cause myocardial injury, contributing to the progression of the underlying heart disease. The aim was to evaluate whether internal electrical cardioversion (int-CV) via the ICD or conventional external CV (ext-CV) of persistent atrial fibrillation (AF) in heart failure (HF) patients induces myocardial injury and initiates inflammation. METHODS AND RESULTS: A total of 115 HF patients with an ejection fraction between 20% and 45% were prospectively enrolled...
March 12, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29533251/prevalence-of-myocardial-fibrosis-by-left-ventricular-assist-device-apical-core-biopsy-and-correlation-with-other-markers-of-myocardial-recovery
#16
Jessica Schultz, Ranjit John, Cindy Martin, Forum Kamdar, Thenappan Thenappan, Rebecca Cogswell
Myocardial fibrosis identified by apical core pathology at the time of left ventricular assist device (LVAD) implantation may add information regarding myocardial recovery potential. In this analysis, we report the prevalence of myocardial fibrosis by cardiomyopathy type and its association with other known markers of left ventricular recovery. Left ventricular assist device core pathology was reviewed on 332 patients who underwent LVAD implantation at a single institution between 2005 and 2016. Baseline clinical and echocardiographic characteristics were compared among patients with and without myocardial fibrosis by cardiomyopathy type...
March 10, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29532140/a-prospective-comparative-study-on-improvement-of-hyperthyroid-cardiovascular-dysfunction-in-patients-undergoing-total-thyroidectomy-versus-medical-management
#17
S Muthukumar, K Ravikumar, S Dhalapathy, T Gomathy, S Umadevi, D Maruthupandian
INTRODUCTION: Cardiovascular dysfunction (CVD) is a well-recognized complication in patients with hyperthyroidism and is the major cause of mortality. Very few studies have compared the outcome of CVD following different treatment modalities. In this study we intended to compare treatment modalities (antithyroid drugs vs surgery) for reversal of CVD. MATERIALS AND METHODS: Patients with newly detected hyperthyroidism were grouped into, Group I [n = 123, age <60 years, undergoing total thyroidectomy], Group II [n = 42, age <60 years, treated with antithyroid medications] were evaluated with 2D echocardiography, serum N terminal pro brain natriuretic peptide (NT-pro-BNP) at the time of diagnosis (Point A), after achieving euthyroidism (Point B) with antithyroid drugs and 6 months after surgery/continuation of antithyroid medications (Point C)...
May 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29531564/efficacy-of-combined-endurance-resistance-training-versus-endurance-training-in-patients-with-heart-failure-after-percutaneous-coronary-intervention-a-randomized-controlled-trial
#18
Sara Abolahrari-Shirazi, Javad Kojuri, Zahra Bagheri, Zahra Rojhani-Shirazi
Background: This study aimed to compare the effects of combined endurance-resistance training (CT) versus endurance training (ET) on some cardiovascular markers in patients with heart failure after percutaneous coronary intervention (PCI). Materials and Methods: The study applied a randomized, controlled design in which 75 patients with heart failure who had undergone PCI were randomly assigned to one of three groups: ET, CT, and control. The ET group performed ET for 45 min, three times a week for 7 weeks...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29516694/-effects-of-moxibustion-on-ventricular-mass-index-and-expression-of-apoptosis-related-proteins-in-myocardium-of-rats-with-chronic-heart-failure
#19
Dan Li, Qing-Ling Li, Qiang Ma, Na-Na Liu, Jia-Hui Yang, Yong-Lei Zeng, Ling He, Hui Tan, Xue-Zhao Jia, Jing Wang
OBJECTIVE: To observe the effect of moxibustion on cardiac function and the expression of B-cell lymphoma-2 (Bcl-2), Bcl-2 associated X (Bax), Fas, Fas ligand (FasL) in cardiomyocytes of chronic heart failure (CHF) rats, so as to explore its underlying mechanisms in preventing and treating CHF. METHODS: SD rats were randomly divided into normal control, model, moxibustion, Captopril and moxibustion + Captopril (M+C) groups ( n =12 rats/group). The CHF model was established by intraperitoneal injection of Adriamycin (ADR, from 1 to 4 mg/kg, once every other day for 15 days)...
February 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29430691/left-ventricular-function-of-patients-with-pregnancy-induced-hypertension-evaluated-using-velocity-vector-imaging-echocardiography-and-n-terminal-pro-brain-natriuretic-peptide
#20
Li Yu, Qichang Zhou, Qinghai Peng, Zurong Yang
PURPOSE: To investigate whether acute and transient pressure overload in patients with pregnancy-induced hypertension (PIH) affects left ventricular (LV) systolic function. METHODS: From pregnancy to 3 months after delivery, 82 patients were analyzed: 27, 25, and 30 with gestational hypertension, preeclampsia, and the healthy control group, respectively. Conventional echocardiography and velocity vector imaging (VVI) were performed, and blood levels of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) were analyzed...
April 2018: Echocardiography
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