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https://www.readbyqxmd.com/read/29333864/non-digestible-carbohydrates-in-infant-formula-as-substitution-for-human-milk-oligosaccharide-functions-effects-on-microbiota-and-gut-maturation
#1
Renate Akkerman, Marijke M Faas, Paul de Vos
Human milk (HM) is the golden standard for nutrition of newborn infants. Human milk oligosaccharides (HMOs) are abundantly present in HM and exert multiple beneficial functions, such as support of colonization of the gut microbiota, reduction of pathogenic infections and support of immune development. HMO-composition is during lactation continuously adapted by the mother to accommodate the needs of the neonate. Unfortunately, for many valid reasons not all neonates can be fed with HM and are either totally or partly fed with cow-milk derived infant formulas, which do not contain HMOs...
January 15, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29330270/cutis-marmorata-telangiectatica-congenita-and-major-lower-limb-asymmetry
#2
Joana Amaral, Sara Peixoto, Gabriela Mimoso, Dolores Pereira
A 39-week-old male newborn presented at birth with atrophic erythematous and purpuric skin lesions, in a typical right-sided segmental distribution. Lesions were persistent and unaffected by rewarming in the postpartum period. Postnatal echocardiogram showed a predominance of the right cavities and an upper atrial septal defect. Cerebral and abdominal ultrasound were normal along with ophthalmological examination. On follow-up, lower limbs asymmetry was noted. The right lower limb was shorter in length and had a smaller diameter...
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29317419/cohort-profile-effect-of-malaria-in-early-pregnancy-on-fetal-growth-in-benin-recipal-preconceptional-cohort
#3
Manfred Accrombessi, Emmanuel Yovo, Gilles Cottrell, Gino Agbota, Agnès Gartner, Yves Martin-Prevel, Nadia Fanou-Fogny, Diane Djossinou, Jennifer Zeitlin, Nicaise Tuikue-Ndam, Florence Bodeau-Livinec, Sandrine Houzé, Nicola Jackson, Paul Ayemonna, Achille Massougbodji, Michel Cot, Nadine Fievet, Valérie Briand
PURPOSE: REtard de Croissance Intra-uterin et PALudisme (RECIPAL) is an original preconceptional cohort designed to assess the consequences of malaria during the first trimester of pregnancy, which is a poorly investigated period in Africa and during which malaria may be detrimental to the fetus. PARTICIPANTS: For this purpose, a total of 1214 women of reproductive age living in Sô-Ava and Akassato districts (south Benin) were followed up monthly from June 2014 to December 2016 until 411 of them became pregnant...
January 8, 2018: BMJ Open
https://www.readbyqxmd.com/read/29316198/co-causation-of-reduced-newborn-size-by-maternal-undernutrition-infections-and-inflammation
#4
Per Ashorn, Lotta Hallamaa, Lindsay H Allen, Ulla Ashorn, Upeksha Chandrasiri, Megan Deitchler, Ronan Doyle, Ulla Harjunmaa, Josh M Jorgensen, Steve Kamiza, Nigel Klein, Kenneth Maleta, Minyanga Nkhoma, Brietta M Oaks, Basho Poelman, Stephen J Rogerson, Christine P Stewart, Mamane Zeilani, Kathryn G Dewey
More than 20 million babies are born with low birthweight annually. Small newborns have an increased risk for mortality, growth failure, and other adverse outcomes. Numerous antenatal risk factors for small newborn size have been identified, but individual interventions addressing them have not markedly improved the health outcomes of interest. We tested a hypothesis that in low-income settings, newborn size is influenced jointly by multiple maternal exposures and characterized pathways associating these exposures with newborn size...
January 8, 2018: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29311590/vitamin-a-and-e-nutritional-status-in-relation-to-leptin-adiponectin-igf-i-and-igf-ii-in-early-life-a-birth-cohort-study
#5
Qinwen Du, Zhong-Cheng Luo, Anne Monique Nuyt, Francois Audibert, Pierre Julien, Shu-Qin Wei, Dan-Li Zhang, William Fraser, Emile Levy
The metabolic health effects of vitamin A and E nutritional status in early life are largely unknown. We assessed whether vitamin A and vitamin E nutritional status may affect circulating leptin, adiponectin, insulin-like growth factor (IGF)-I and IGF-II levels in early life in humans. In a singleton birth cohort (n = 248), vitamin A and E nutritional status in fetuses/newborns were assessed by cord plasma concentrations of retinol, β-carotene, α- and γ-tocopherols. The primary outcomes were cord plasma leptin, adiponectin, IGF-I and IGF-II concentrations...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29309515/infant-feeding-in-relation-to-the-risk-of-advanced-islet-autoimmunity-and-type-1-diabetes-in-children-with-increased-genetic-susceptibility-a-cohort-study
#6
Leena Hakola, Hanna-Mari Takkinen, Sari Niinistö, Suvi Ahonen, Jaakko Nevalainen, Riitta Veijola, Jorma Ilonen, Jorma Toppari, Mikael Knip, Suvi M Virtanen
Breastfeeding, age at introduction of foods, and food diversity in infancy were studied for associations with advanced islet autoimmunity and type 1 diabetes. During 1996--2004, a total of 5,915 newborns with human leukocyte antigen-conferred susceptibility to type 1 diabetes were enrolled in the prospective Finnish Type 1 Diabetes Prediction and Prevention Nutrition Study. Children were assessed at intervals of 3-12 months for the appearance of 4 types of islet autoantibodies and type 1 diabetes up to the age of 15 years...
January 1, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29305749/dna-methylation-variability-in-a-single-locus-of-the-rxr%C3%AE-promoter-from-umbilical-vein-blood-at-term-pregnancy
#7
Diana Chávez-Lizárraga, Paola Zárate-Segura, Jorge Beltrán-Montoya, Carmen Canchola-Sotelo, Felipe Vadillo-Ortega, Erika Chavira-Suárez
DNA methylation status of RXRα gene promoter has been correlated with maternal diet during early pregnancy, and associated with offspring's adiposity and bone mineral content. In adult life, increased methylation of RXRα promoter region is associated with myocardium pathologies. Early growth response proteins (EGR) are zinc finger transcription factors associated with several cellular pathways such as inflammation, apoptosis, and cardiopathies. DNA-binding sequences of EGR proteins have been reported in the RXRα gene promoter using chromatin immunoprecipitation methods...
January 6, 2018: Biochemical Genetics
https://www.readbyqxmd.com/read/29303286/-cystic-fibrosis-in-adults
#8
Libor Fila
Cystic fibrosis (CF) is an inherited disease caused by mutations in the transmembrane conductance regulator (CFTR) gene. The disease leads to dysfunction of the exocrine glands with high concentration of chloride in the sweat and formation of abnormally viscous mucus in the respiratory, digestive and reproductive tract. Chronic sinopulmonary disease, exocrine pancreatic insufficiency, liver disease, intestinal obstruction, impaired nutritional status, salt loss syndrome and male infertility dominates in the clinical presentation...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29302553/breastfeeding-practice-and-knowledge-among-women-attending-primary-health-care-centers-in-riyadh-2016
#9
Norah Faleh Al-Mutairi, Yousef Abdullah Al-Omran, P J Parameaswari
Introduction: Breast milk is the best natural essential nutrition to newborns and infants. However, the practice of breastfeeding (BF) has declined in Saudi Arabia. Objective: The objective of this study was to assess the knowledge and practice of BF with their determinants among mothers in Riyadh. Materials and Methods: In this cross-sectional study, 252 mothers attending the well-baby clinics in Riyadh from March 2016 to May 2017 were selected randomly with their consent and studied by a standardized questionnaire...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29302313/the-national-evaluation-platform-for-maternal-newborn-and-child-health-and-nutrition-from-idea-to-implementation
#10
REVIEW
Rebecca Heidkamp
No abstract text is available yet for this article.
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29301912/monitoring-the-postnatal-growth-of-preterm-infants-a-paradigm-change
#11
REVIEW
Jose Villar, Francesca Giuliani, Fernando Barros, Paola Roggero, Irma Alejandra Coronado Zarco, Maria Albertina S Rego, Roseline Ochieng, Maria Lorella Gianni, Suman Rao, Ann Lambert, Irina Ryumina, Carl Britto, Deepak Chawla, Leila Cheikh Ismail, Syed Rehan Ali, Jane Hirst, Jagjit Singh Teji, Karim Abawi, Jacqueline Asibey, Josephine Agyeman-Duah, Kenny McCormick, Enrico Bertino, Aris T Papageorghiou, Josep Figueras-Aloy, Zulfiqar Bhutta, Stephen Kennedy
There is no consensus regarding how the growth of preterm infants should be monitored or what constitutes their ideal pattern of growth, especially after term-corrected age. The concept that the growth of preterm infants should match that of healthy fetuses is not substantiated by data and, in practice, is seldom attained, particularly for very preterm infants. Hence, by hospital discharge, many preterm infants are classified as postnatal growth-restricted. In a recent systematic review, 61 longitudinal reference charts were identified, most with considerable limitations in the quality of gestational age estimation, anthropometric measures, feeding regimens, and how morbidities were described...
January 4, 2018: Pediatrics
https://www.readbyqxmd.com/read/29299997/systemic-and-local-cues-drive-neural-stem-cell-niche-remodelling-during-neurogenesis-in-drosophila
#12
Pauline Spéder, Andrea H Brand
Successful neurogenesis requires adequate proliferation of neural stem cells (NSCs) and their progeny, followed by neuronal differentiation, maturation and survival. NSCs inhabit a complex cellular microenvironment, the niche, which influences their behaviour. To ensure sustained neurogenesis, niche cells must respond to extrinsic, environmental changes whilst fulfilling the intrinsic requirements of the neurogenic program and adapting their roles accordingly. However, very little is known about how different niche cells adjust their properties to such inputs...
January 4, 2018: ELife
https://www.readbyqxmd.com/read/29298968/nutrition-during-breastfeeding-impact-on-human-milk-composition
#13
REVIEW
Agnieszka Bzikowska, Aneta Czerwonogrodzka-Senczyna, Aleksandra Wesołowska, Halina Weker
Breastfeeding or breast milk feeding is a gold standard of feeding of newborns and infants. According to the guidelines of the World Health Organisation exclusive feeding with breast milk should be applied until the end of 6 months of age and should be continued during subsequent months with simultaneous introduction of supplementary food. Composition of breast milk varies and the composition of individual nutrients is affected by, among others, the diet of a breastfeeding mother. The paper aimed to present a literature review in order to assess a correlation between the mother's diet and breast milk composition...
December 22, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29297809/congenital-nutritional-myodegeneration-white-muscle-disease-in-a-giraffe-giraffa-camelopardalis-calf
#14
Jan H Bos, Fokko C Klip, Marja J L Kik
It is well known that vitamin E and selenium deficiencies in domestic ruminants can lead to white muscle disease. After a clinically normal gestation period at Ouwehand Zoo in the Netherlands, a newborn giraffe ( Giraffa camelopardalis) calf showed clinical signs of white muscle disease almost immediately after birth. The calf was rejected by the mother and was euthanized 3 days later because of deterioration of clinical signs. At necropsy, pulmonary edema and pallor of skeletal and heart muscles was noted...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29294576/-study-on-the-risk-of-mortality-and-associated-factors-among-hiv-exposed-children-in-henan-province-2002-2014
#15
Q Wang, N Ma, H Si, Y M Ma, N Li, Y G Nie, D Y Sun, Z Wang
Objective: To investigate the status of survival and related risk factors among HIV-exposed children in Henan province from 2002 to 2014. Methods: A follow-up program was set up when infants as 1, 3, 6, 9, 12, 18 month olds. Data regarding the HIV-exposed children and their mothers were collected, including service of PMTCT, antiviral therapy, incidence of infectious disease and survival status of infants. Univariate and multivariate logistic regression models were used to explore the risk factors. Results: A total number of 1 705 HIV-infected infants were reported from 2002 to 2014...
December 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/29289991/effects-of-dietary-advice-on-insulin-like-growth-factors-among-healthy-newborns
#16
Emre Özgür Bulduk, Sıdıka Bulduk, Burcu Biral Coşkun
OBJECTIVES: In fetal life, insulin, insulin-like growth factor (IGF) 1, IGF 2 and IGF-binding protein (IGFBP) 3 are essential growth factors. The purpose of this study is to investigate the effects of dietary intervention on insulin-like growth factors in the cord blood of neonates. METHODS: The study involved 52 pregnant women who were followed up in Gazi University Medical School Hospital at Ankara, Turkey. They were randomly divided into two groups: The experimental group was involved in nutrition education...
December 30, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29285339/medium-chain-acyl-coa-dehydrogenase-deficiency-in-a-premature-infant
#17
Steven F Dobrowolski, Lina Ghaloul-Gonzalez, Jerry Vockley
Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is identified by newborn screening (NBS). The natural history of MCADD includes metabolic decompensation with hypoglycemia, hyperammonemia, seizures, coma, and death. NBS enables expectant management thus severe symptoms are rare in managed patients. We report premature birth of an MCADD affected infant and resultant management challenges. Nutritional support advanced from parenteral nutrition at 24 hours to enteral feeds. A NBS sample was collected day 2, positive results for MCADD was reported day six, and diagnostic tests were performed day seven...
November 21, 2017: Pediatric Reports
https://www.readbyqxmd.com/read/29273309/the-satisfactory-growth-and-development-at-2-years-of-age-of-the%C3%A2-intergrowth-21st-fetal-growth-standards-cohort-support-its%C3%A2-appropriateness-for-constructing-international-standards
#18
José Villar, Leila Cheikh Ismail, Eleonora Staines Urias, Francesca Giuliani, Eric O Ohuma, Cesar G Victora, Aris T Papageorghiou, Douglas G Altman, Cutberto Garza, Fernando C Barros, Fabien Puglia, Roseline Ochieng, Yasmin A Jaffer, Julia A Noble, Enrico Bertino, Manorama Purwar, Ruyan Pang, Ann Lambert, Cameron Chumlea, Alan Stein, Michelle Fernandes, Zulfiqar A Bhutta, Stephen H Kennedy
BACKGROUND: The World Health Organization recommends that human growth should be monitored with the use of international standards. However, in obstetric practice, we continue to monitor fetal growth using numerous local charts or equations that are based on different populations for each body structure. Consistent with World Health Organization recommendations, the INTERGROWTH-21st Project has produced the first set of international standards to date pregnancies; to monitor fetal growth, estimated fetal weight, Doppler measures, and brain structures; to measure uterine growth, maternal nutrition, newborn infant size, and body composition; and to assess the postnatal growth of preterm babies...
December 19, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29259931/bone-marrow-necrosis-and-fat-embolism-syndrome-a-dreadful-complication-of-hemoglobin-sickle-cell-disease
#19
Eduardo Pelegrineti Targueta, André Carramenha de Góes Hirano, Fernando Peixoto Ferraz de Campos, João Augusto Dos Santos Martines, Silvana Maria Lovisolo, Aloisio Felipe-Silva
Sickle cell disease encompasses a wide range of genotypic presentation with particular clinical features. The entity affects millions of people, particularly those whose ancestors came from sub-Saharan Africa and other countries in the Western Hemisphere, Saudi Arabia, and India. Currently, the high frequency of S and C genes reflects natural selection through the protection of heterozygotes against severe malaria, the high frequency of consanguineous marriages, improvement of some public health policies and the nutritional standards in the poorer countries where newborns are now living long enough to present for diagnosis and management...
October 2017: Autopsy & Case Reports
https://www.readbyqxmd.com/read/29248382/risk-factors-for-nosocomial-infections-after-cardiac-surgery-in-newborns-with-congenital-heart-disease
#20
Heladia García, Beatriz Cervantes-Luna, Héctor González-Cabello, Guadalupe Miranda-Novales
BACKGROUND: Congenital heart diseases are among the most common congenital malformations. Approximately 50% of the patients with congenital heart disease undergo cardiac surgery. Nosocomial infections (NIs) are the main complications and an important cause of increased morbidity and mortality associated with congenital heart diseases. This study's objective was to identify the risk factors associated with the development of NIs after cardiac surgery in newborns with congenital heart disease...
November 23, 2017: Pediatrics and Neonatology
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