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https://www.readbyqxmd.com/read/28633322/the-detrimental-consequences-of-overestimating-future-health-in-late-life
#1
Jeremy M Hamm, Stefan T Kamin, Judith G Chipperfield, Raymond P Perry, Frieder R Lang
Objectives: Although forecasting a positive future can be adaptive, it may not be when expectations are unmet. Our study examined whether such inaccurate expectations about future health status (overestimation) were maladaptive for older adults who commonly experience late life declines in physical functioning. Method: We analyzed data from the nationally representative German Aging Survey (DEAS; 1996-2011; n = 2,539; age range 60-85 years) using multilevel growth models that assessed the influence of inaccurate health expectations on older adults' physical functioning over a 9-year period...
June 13, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28630627/changes-in-polyphenols-contents-and-antioxidant-capacities-of-organically-and-conventionally-cultivated-tomato-solanum-lycopersicum-l-fruits-during-ripening
#2
Dea Anton, Ingrid Bender, Tanel Kaart, Mati Roasto, Marina Heinonen, Anne Luik, Tõnu Püssa
Polyphenols of fruits and vegetables form an important part of human dietary compounds. Relatively little is known about accumulation of phenolics during fruits ripening process. The goal of this work was to study the changes in antioxidant activity and in content of 30 polyphenols during ripening of tomato fruits. Five organically and conventionally grown tomato cultivars were investigated at three different ripening stages. Phenolic compounds were extracted with methanol and extracts were analyzed by HPLC-DAD-MS/MS...
2017: International Journal of Analytical Chemistry
https://www.readbyqxmd.com/read/28608318/denitrifying-bacterial-communities-display-different-temporal-fluctuation-patterns-across-dutch-agricultural-soils
#3
Nguyen E López-Lozano, Michele C Pereira E Silva, Franck Poly, Nadine Guillaumaud, Jan Dirk van Elsas, Joana Falcão Salles
Considering the great agronomic and environmental importance of denitrification, the aim of the present study was to study the temporal and spatial factors controlling the abundance and activity of denitrifying bacterial communities in a range of eight agricultural soils over 2 years. Abundance was quantified by qPCR of the nirS, nirK and nosZ genes, and the potential denitrification enzyme activity (DEA) was estimated. Our data showed a significant temporal variation considerably high for the abundance of nirK-harboring communities, followed by nosZ and nirS communities...
June 12, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/28603892/flexible-zinc-tin-oxide-thin-film-transistors-operating-at-1-kv-for-integrated-switching-of-dielectric-elastomer-actuators-arrays
#4
Alexis Marette, Alexandre Poulin, Nadine Besse, Samuel Rosset, Danick Briand, Herbert Shea
Flexible high-voltage thin-film transistors (HVTFTs) operating at more than 1 kV are integrated with compliant dielectric elastomer actuators (DEA) to create a flexible array of 16 independent actuators. To allow for high-voltage operation, the HVTFT implements a zinc-tin oxide channel, a thick dielectric stack, and an offset gate. At a source-drain bias of 1 kV, the HVTFT has a 20 µA on-current at a gate voltage bias of 30 V. Their electrical characteristics enable the switching of DEAs which require drive voltages of over 1 kV, making control of an array simpler in comparison to the use of external high-voltage switching...
June 12, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28601863/the-curvilinear-effect-of-bmi-on-functional-health-evidence-of-the-long-running-german-ageing-survey
#5
André Hajek, Hans-Helmut König
AIMS: We aimed at determining the effect of BMI on functional health among older Germans longitudinally. METHODS: Data from four waves (2002-2014) of the German Ageing Survey ('Deutscher Alterssurvey'; DEAS), a representative sample of community-dwelling individuals aged 40 years and above, were used. Functional health was quantified by the subscale 'physical functioning' of the 36-Item Short Form Health Survey (SF-36). Fixed effects regressions were used to estimate the predictors of functional health...
June 10, 2017: Obesity Facts
https://www.readbyqxmd.com/read/28599949/quetiapine-extended-release-versus-aripiprazole-in-children-and-adolescents-with-first-episode-psychosis-the-multicentre-double-blind-randomised-tolerability-and-efficacy-of-antipsychotics-tea-trial
#6
Anne Katrine Pagsberg, Pia Jeppesen, Dea Gowers Klauber, Karsten Gjessing Jensen, Ditte Rudå, Marie Stentebjerg-Olesen, Peter Jantzen, Simone Rasmussen, Eva Ann-Sofie Saldeen, Maj-Britt Glenn Lauritsen, Niels Bilenberg, Anne Dorte Stenstrøm, Louise Nyvang, Sarah Madsen, Thomas M Werge, Theis Lange, Christian Gluud, Maria Skoog, Per Winkel, Jens Richardt M Jepsen, Birgitte Fagerlund, Christoph U Correll, Anders Fink-Jensen
BACKGROUND: Head-to-head trials to guide antipsychotic treatment choices for paediatric psychosis are urgently needed because extrapolations from adult studies might not be implementable. In this superiority trial with two-sided significance testing, we aimed to compare the efficacy and safety of quetiapine-extended release (quetiapine-ER) versus aripiprazole in children and adolescents with first-episode psychosis, to determine whether differences between the two treatments were sufficient to guide clinicians in their choice of one drug over the other...
June 6, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28590860/inclusion-of-disability-status-in-investigations-of-child-maltreatment-lifetime-prevalence
#7
Myriah E McNew, Dea Garic
No abstract text is available yet for this article.
July 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28574782/rna-based-ovarian-cancer-research-from-a-gene-to-systems-biomedicine-perspective
#8
Esra Gov, Medi Kori, Kazim Yalcin Arga
Ovarian cancer remains the leading cause of death from a gynecologic malignancy, and treatment of this disease is harder than any other type of female reproductive cancer. Improvements in the diagnosis and development of novel and effective treatment strategies for complex pathophysiologies, such as ovarian cancer, require a better understanding of disease emergence and mechanisms of progression through systems medicine approaches. RNA-level analyses generate new information that can help in understanding the mechanisms behind disease pathogenesis, to identify new biomarkers and therapeutic targets and in new drug discovery...
August 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/28574273/breathable-microgel-colloidosome-gas-switchable-microcapsules-with-o2-and-co2-tunable-shell-permeability-for-hierarchical-size-selective-control-release
#9
Lei Lei, Qi Zhang, Shuxian Shi, Shiping Zhu
Microcapsules enabling precise delivery and controlled release are highly desirable. However, it is still challenging to control the release profile by regulating the microcapsule shell permeability. In this work, gas-switchable microgel colloidosome (MGC) with oxygen (O2) and carbon dioxide (CO2) dual gas-tunable shell permeability has been developed and tested for control release of water-soluble cargo molecules, based on the size exclusion mechanism. The O2 and CO2 dual gas-switchable poly(2-(diethylamino)ethyl methacrylate-co-2,3,4,5,6-pentafluorostyrene), P(DEA-co-FS), microgels having surface modified with amino group (-NH2) were synthesized and used to stabilize oil-in-water (O/W) Pickering emulsions...
June 8, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28570507/trends-in-prevalence-of-advanced-hiv-disease-at-antiretroviral-therapy-enrollment-10-countries-2004-2015
#10
Andrew F Auld, Ray W Shiraishi, Ikwo Oboho, Christine Ross, Moses Bateganya, Valerie Pelletier, Jacob Dee, Kesner Francois, Nirva Duval, Mayer Antoine, Chris Delcher, Gracia Desforges, Mark Griswold, Jean Wysler Domercant, Nadjy Joseph, Varough Deyde, Yrvel Desir, Joelle Deas Van Onacker, Ermane Robin, Helen Chun, Isaac Zulu, Ishani Pathmanathan, E Kainne Dokubo, Spencer Lloyd, Rituparna Pati, Jonathan Kaplan, Elliot Raizes, Thomas Spira, Kiren Mitruka, Aleny Couto, Eduardo Samo Gudo, Francisco Mbofana, Melissa Briggs, Charity Alfredo, Carla Xavier, Alfredo Vergara, Ndapewa Hamunime, Simon Agolory, Gram Mutandi, Naemi N Shoopala, Souleymane Sawadogo, Andrew L Baughman, Adebobola Bashorun, Ibrahim Dalhatu, Mahesh Swaminathan, Dennis Onotu, Solomon Odafe, Oseni Omomo Abiri, Henry H Debem, Hank Tomlinson, Velephi Okello, Peter Preko, Trong Ao, Caroline Ryan, George Bicego, Peter Ehrenkranz, Harrison Kamiru, Harriet Nuwagaba-Biribonwoha, Gideon Kwesigabo, Angela A Ramadhani, Kahemele Ng'wangu, Patrick Swai, Mohamed Mfaume, Ramadhani Gongo, Deborah Carpenter, Timothy D Mastro, Carol Hamilton, Julie Denison, Fred Wabwire-Mangen, Olivier Koole, Kwasi Torpey, Seymour G Williams, Robert Colebunders, Julius N Kalamya, Alice Namale, Michelle R Adler, Bridget Mugisa, Sundeep Gupta, Sharon Tsui, Eric van Praag, Duc B Nguyen, Sheryl Lyss, Yen Le, Abu S Abdul-Quader, Nhan T Do, Modest Mulenga, Sebastian Hachizovu, Owen Mugurungi, Beth A Tippett Barr, Elizabeth Gonese, Tsitsi Mutasa-Apollo, Shirish Balachandra, Stephanie Behel, Trista Bingham, Duncan Mackellar, David Lowrance, Tedd V Ellerbrock
Monitoring prevalence of advanced human immunodeficiency virus (HIV) disease (i.e., CD4+ T-cell count <200 cells/μL) among persons starting antiretroviral therapy (ART) is important to understand ART program outcomes, inform HIV prevention strategy, and forecast need for adjunctive therapies.*(,)(†)(,)(§) To assess trends in prevalence of advanced disease at ART initiation in 10 high-burden countries during 2004-2015, records of 694,138 ART enrollees aged ≥15 years from 797 ART facilities were analyzed...
June 2, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28562753/group-b-streptococcus-detection-in-pregnant-women-via-culture-and-pcr-methods
#11
Cláudia Wollheim, Rosa Dea Sperhacke, Sabrina Kahler Ribeiro Fontana, Andréa Cristina Vanni, Sérgio Kakuta Kato, Patricia Regina de Araújo, Afonso Luis Barth, José Mauro Madi
INTRODUCTION: Group B Streptococcus (GBS), a source of neonatal infection, colonizes the gastrointestinal and genitourinary tracts of pregnant women. Routine screening for maternal GBS in late pregnancy and consequent intrapartum antibiotic prophylaxis have reduced the incidence of early-onset GBS neonatal infection. The aim of this study was to evaluate the performance of PCR, compared to culture (gold standard), in GBS colonization screening of pregnant women, and to establish the prevalence of GBS colonization among this population...
March 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28556539/simple-rapid-and-environmentally-friendly-method-for-the-separation-of-isoflavones-using-ultra-high-performance-supercritical-fluid-chromatography
#12
Wenjie Wu, Yuan Zhang, Hanqiu Wu, Weie Zhou, Yan Cheng, Hongna Li, Chuanbin Zhang, Lulu Li, Ying Huang, Feng Zhang
Isoflavones are natural substances that exhibit hormone-like pharmacological activities. The separation of isoflavones remains an analytical challenge because of their similar structures. We show that ultra-high performance supercritical fluid chromatography can be an appropriate tool to achieve the fast separation of 12 common dietary isoflavones. Among the five tested columns the Torus DEA column was found to be the most effective column for the separation of these isoflavones. The impact of individual parameters on the retention time and separation factor was evaluated...
May 27, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28550341/development-of-a-risk-algorithm-to-better-target-sti-testing-and-treatment-among-australian-aboriginal-and-torres-strait-islander-people
#13
Handan Wand, Joanne Bryant, Marian Pitts, Dea Delaney-Thiele, John M Kaldor, Heather Worth, James Ward
Identifying and targeting those at greatest risk will likely play a significant role in developing the most efficient and cost-effective sexually transmissible infections (STI) prevention programs. We aimed to develop a risk prediction algorithm to identify those who are at increased risk of STI. A cohort (N = 2320) of young sexually active Aboriginal and Torres Strait Islander people (hereafter referred to as Aboriginal people) were included in this study. The primary outcomes were self-reported high-risk sexual behaviors and past STI diagnosis...
May 26, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28545456/towards-an-equitable-healthcare-in-china-evaluating-the-productive-efficiency-of-community-health-centers-in-jiangsu-province
#14
Lulin Zhou, Xinglong Xu, Henry Asante Antwi, Linna Wang
BACKGROUND: While the demand for the health service keeps escalating at the grass root or rural areas of China, a substantial portion of healthcare resources remains stagnant in the more developed cities and this has entrenched health inequity in many parts of China. At its conception, the Deepening Health Care Reform in 2012 China was intended to flush out these discrepancies and promote a more equitable and efficient distribution of health resources. Nearly half a decade of this reform, there are uncertainties as to whether the attainment of the objectives of the reform is in sight...
May 25, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28544336/regulation-of-controlled-substance-prescribing-an-overview-for-certified-nurse-midwives-and-certified-midwives
#15
Kathryn Osborne
In addition to the regulation of prescriptive authority and prescribing practices conducted by individual states, the prescription of controlled substances is also regulated at the federal level by the US Drug Enforcement Administration (DEA). While there are variations in state laws relative to controlled substance prescribing, federal law is uniform across states as established by the Controlled Substances Act (21 United States Code § 801-890) and the DEA Regulations (Title 21, Code of Federal Regulations)...
May 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28542362/a-window-dea-based-efficiency-evaluation-of-the-public-hospital-sector-in-greece-during-the-5-year-economic-crisis
#16
Angeliki Flokou, Vassilis Aletras, Dimitris Niakas
The main objective of this study was to apply the non-parametric method of Data Envelopment Analysis (DEA) to measure the efficiency of Greek NHS hospitals between 2009-2013. Hospitals were divided into four separate groups with common characteristics which allowed comparisons to be carried out in the context of increased homogeneity. The window-DEA method was chosen since it leads to increased discrimination on the results especially when applied to small samples and it enables year-by-year comparisons of the results...
2017: PloS One
https://www.readbyqxmd.com/read/28528092/structural-strength-analysis-of-amorphous-trehalose-maltodextrin-systems
#17
V A Maidannyk, B Nurhadi, Y H Roos
Fundamental knowledge of physical state of materials gives practically important information for food, biological and pharmaceutical industry. Based on Williams-Landel-Ferry (WLF) equation, the strength concept was introduced. This concept provides a simple parameter, S, to express resistance of solids to flow above the glass transition temperature. To develop this approach, miscible trehalose-maltodextrin (0:100; 20:80; 40:60; 60:40; 80:20 and 100:0) systems with different ratios of components were used in the present study...
June 2017: Food Research International
https://www.readbyqxmd.com/read/28508651/sugar-breathing-glycopolymersomes-for-regulating-glucose-level
#18
Yufen Xiao, Hui Sun, Jianzhong Du
Diabetes mellitus is a chronic, life-threatening illness that affects people of every age and ethnicity. It is a long-term pain for those who are affected and must regulate their blood glucose level by frequent subcutaneous injection of insulin every day. Herein, we propose a noninsulin and antidiabetic drug-free strategy for regulating blood glucose level by a nanosized "sugar sponge" which is a lectin-bound glycopolymersome capable of regulating glucose due to the dynamic recognition between the lectin and different carbohydrates...
June 7, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28502766/anterior-cingulate-serotonin-1b-receptor-binding-is-associated-with-emotional-response-inhibition
#19
Sofi da Cunha-Bang, Liv Vadskjær Hjordt, Vibeke Høyrup Dam, Dea Siggaard Stenbæk, Dorte Sestoft, Gitte M Knudsen
Serotonin has a well-established role in emotional processing and is a key neurotransmitter in impulsive aggression, presumably by facilitating response inhibition and regulating subcortical reactivity to aversive stimuli. In this study 44 men, of whom 19 were violent offenders and 25 were non-offender controls, completed an emotional Go/NoGo task requiring inhibition of prepotent motor responses to emotional facial expressions. We also measured cerebral serotonin 1B receptor (5-HT1BR) binding with [(11)C]AZ10419369 positron emission tomography within regions of the frontal cortex...
May 8, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28492652/low-energy-electron-induced-decomposition-of-%C3%AE-3-c3h5-ru-co-3br-a-potential-focused-electron-beam-induced-deposition-precursor-with-a-heteroleptic-ligand-set
#20
Rachel M Thorman, Joseph A Brannaka, Lisa McElwee-White, Oddur Ingólfsson
Here we describe in detail low energy electron induced fragmentation of a potential focused electron beam induced deposition (FEBID) precursor, π-allyl ruthenium tricarbonyl bromide, i.e. (η(3)-C3H5)Ru(CO)3Br, specially designed to allow comparison of the effect of different ligands on the efficiency of low energy electron induced fragmentation of FEBID precursors. Specifically, we discuss the efficiency of dissociative electron attachment (DEA) and dissociative ionization (DI) with respect to electron-induced removal of the allyl, bromide and carbonyl ligands...
May 24, 2017: Physical Chemistry Chemical Physics: PCCP
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