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https://www.readbyqxmd.com/read/28719229/experiences-using-pre-exposure-prophylaxis-for-safer-conception-among-hiv-serodiscordant-heterosexual-couples-in-the-united-states
#1
Angela R Bazzi, Ashley A Leech, Dea L Biancarelli, Meg Sullivan, Mari-Lynn Drainoni
Antiretroviral pre-exposure prophylaxis (PrEP) is a promising HIV prevention strategy for HIV serodiscordant couples (HIV-infected male, uninfected female) seeking safer conception. However, most research on PrEP for safer conception has focused on couples in sub-Saharan Africa; little is known about the perspectives or experiences of heterosexual couples in the United States. We conducted qualitative interviews with six couples (six women and five of their male partners) receiving PrEP for conception services at an urban safety net hospital in the US Northeast...
July 18, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28717637/phage-therapy-in-a-16-year-old-boy-with-netherton-syndrome
#2
Pikria Zhvania, Naomi Sulinger Hoyle, Lia Nadareishvili, Dea Nizharadze, Mzia Kutateladze
Netherton syndrome (NS) is a rare autosomal recessive disorder, characterized by a classical triad of clinical features, including congenital ichthyosiform erythroderma, trichorrhexis invaginata, and atopic diathesis coupled with frequent bacterial infections (1). The genetic basis for the disease has been recently identified with mutations in gene SPINK5, which is involved in the regulation of formation of skin barriers. We report on a 16-year-old male with all the typical manifestations of NS, including atopic diathesis and ongoing serious staphylococcal infections and allergy to multiple antibiotics whose family sought help at the Eliava Phage Therapy Center when all other treatment options were failing...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28715162/designation-of-alpha-phenylacetoacetonitrile-apaan-a-precursor-chemical-used-in-the-illicit-manufacture-of-phenylacetone-methamphetamine-and-amphetamine-as-a-list-i-chemical-final-rule
#3
(no author information available yet)
The Drug Enforcement Administration (DEA) is finalizing the designation of the chemical alpha-phenylacetoacetonitrile (APAAN) and its salts, optical isomers, and salts of optical isomers, as a list I chemical under the Controlled Substances Act (CSA). The DEA proposed control of APAAN, due to its use in clandestine laboratories to illicitly manufacture the schedule II controlled substances phenylacetone (also known as phenyl-2-propanone or P2P), methamphetamine, and amphetamine. This rulemaking finalizes, without change, the control of APAAN as a list I chemical...
July 14, 2017: Federal Register
https://www.readbyqxmd.com/read/28714830/efficiency-of-inpatient-orthopedic-surgery-in-japan-a-medical-claims-database-analysis
#4
Yoshinori Nakata, Tatsuya Yoshimura, Yuichi Watanabe, Hiroshi Otake, Giichiro Oiso, Tomohiro Sawa
Purpose The purpose of this paper is to determine the characteristics of healthcare facilities that produce the most efficient inpatient orthopedic surgery using a large-scale medical claims database in Japan. Design/methodology/approach Reimbursement claims data were obtained from April 1 through September 30, 2014. Input-oriented Banker-Charnes-Cooper model of data envelopment analysis (DEA) was employed. The decision-making unit was defined as a healthcare facility where orthopedic surgery was performed...
July 10, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28712077/insecticidal-effect-and-impact-of-fitness-of-three-diatomaceous-earths-on-different-maize-hybrids-for-the-eco-friendly-control-of-the-invasive-stored-product-pest-prostephanus-truncatus-horn
#5
Nickolas G Kavallieratos, Christos G Athanassiou, Gerassimos G Peteinatos, Maria C Boukouvala, Giovanni Benelli
Diatomaceous earths (DEs) are able to successfully protect grain commodities from noxious stored-product insect and mite infestations; however, their effectiveness may be moderated by the grain hybrid or variety they are applied to. There is a gap of information on the comparison of the efficacy of different DEs when are applied on different maize hybrids against Prostephanus truncatus (Horn). Therefore, here we tested three commercially available DEs (DEA-P at 75 and 150 ppm, Protect-It at 500 ppm, and PyriSec at 500 ppm) on five different maize hybrids (Calaria, Doxa, Rio Grande, Sisco, and Studio) for the control of P...
July 15, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28709946/frailty-and-sarcopenia-do-not-predict-adverse-events-in-an-elderly-population-undergoing-non-complex-primary-elective-surgery-for-degenerative-conditions-of-the-lumbar-spine
#6
Raphaële Charest-Morin, John Street, Honglin Zhang, Taren Roughead, Tamir Ailon, Michael Boyd, Marcel Dvorak, Brian Kwon, Scott Paquette, Nicolas Dea, Charles G Fisher, Alana M Flexman
BACKGROUND CONTEXT: Sarcopenia measured by normalized total psoas area (NTPA) has been shown to predict mortality and adverse events (AE) in numerous surgical populations. The relationship between sarcopenia and postoperative outcomes after surgery for degenerative spine disease (DSD) has not been investigated. PURPOSE: This study aimed to determine the relationships between sarcopenia, frailty and postoperative adverse events in the elderly DSD population. Secondary objectives were to describe the distribution and predictors of NTPA and to determine the relationship between sarcopenia, frailty and length of stay, discharge to a facility and in-hospital mortality...
July 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28709422/evaluation-on-equality-and-efficiency-of-health-resources-allocation-and-health-services-utilization-in-china
#7
Jian Sun, Hongye Luo
BACKGROUND: China is faced with a daunting challenge to equality and efficiency in health resources allocation and health services utilization in the context of rapid economic growth. This study sought to evaluate the equality and efficiency of health resources allocation and health services utilization in China. METHODS: Demographic, economic, and geographic area data was sourced from China Statistical Yearbook 2012-2016. Data related to health resources and health services was obtained from China Health Statistics Yearbook 2012-2016...
July 14, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28695572/isomer-selectivity-in-low-energy-electron-attachment-to-nitroimidazoles
#8
Anita Ribar, Katharina Fink, Michael Probst, Stefan E Huber, Linda Feketeová, Stephan Denifl
Low-energy electrons effectively decompose the isomers 2-nitroimidazole and 4(5)-nitroimidazole by dissociative electron attachment (DEA) into a variety of fragment anions and radicals. We show in the present study that a distinct selectivity in the DEA reactions for the two isomers occurs. Several new decay channels are observed for 2-nitroimidazole including a dominant one leading to the loss of molecular H2O via the attachment of a low-energy electron. In contrast, the loss of a single hydrogen atom is a much more efficient reaction in DEA to 4(5)-nitroimidazole...
July 11, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28691588/the-relation-between-the-motor-evoked-potential-and-diffusion-tensor-tractography-for-the-corticospinal-tract-in-chronic-hemiparetic-patients-with-cerebral-infarct
#9
Sung Ho Jang, Dea Hee Kim, Seong Ho Kim, Jeong Pyo Seo
We examined the relation between the results of transcranial magnetic stimulation (TMS) and diffusion tensor tractography (DTT) for the corticospinal tract (CST) in chronic hemiparetic patients with a middle cerebral artery (MCA) territory infarct. The amplitude of motor evoked potential (MEP) was closely related to the FN of the CST on DTT in chronic hemiparetic patients with an MCA infarct. We believe that our results would be helpful in more precise estimation of the CST.
July 9, 2017: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/28687994/measurement-and-decomposition-of-energy-efficiency-of-northeast-china-based-on-super-efficiency-dea-model-and-malmquist-index
#10
Xiaojun Ma, Yan Liu, Xiaoxue Wei, Yifan Li, Mengchen Zheng, Yudong Li, Chaochao Cheng, Yumei Wu, Zhaonan Liu, Yuanbo Yu
Nowadays, environment problem has become the international hot issue. Experts and scholars pay more and more attention to the energy efficiency. Unlike most studies, which analyze the changes of TFEE in inter-provincial or regional cities, TFEE is calculated with the ratio of target energy value and actual energy input based on data in cities of prefecture levels, which would be more accurate. Many researches regard TFP as TFEE to do analysis from the provincial perspective. This paper is intended to calculate more reliably by super efficiency DEA, observe the changes of TFEE, and analyze its relation with TFP, and it proves that TFP is not equal to TFEE...
July 7, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28686147/surgical-management-of-spinal-osteoblastomas
#11
Anne L Versteeg, Nicolas Dea, Stefano Boriani, Peter P Varga, Alessandro Luzzati, Michael G Fehlings, Mark H Bilsky, Laurence D Rhines, Jeremy J Reynolds, Mark B Dekutoski, Ziya L Gokaslan, Niccole M Germscheid, Charles G Fisher
OBJECTIVE Osteoblastoma is a rare primary benign bone tumor with a predilection for the spinal column. Although of benign origin, osteoblastomas tend to behave more aggressively clinically than other benign tumors. Because of the low incidence of osteoblastomas, evidence-based treatment guidelines and high-quality research are lacking, which has resulted in inconsistent treatment. The goal of this study was to determine whether application of the Enneking classification in the management of spinal osteoblastomas influences local recurrence and survival time...
July 7, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28670830/resonant-formation-of-strand-breaks-in-sensitized-oligonucleotides-induced-by-low-energy-electrons-0-5-9-0-ev
#12
Ilko Bald, Robin Schürmann, Thupten Tsering, Tanzer Katrin, Stephan Denifl, S V K Kumar
Halogenated nucleobases act as radiosensitizers in cancer radiation therapy, enhancing the reactivity of DNA to secondary low-energy electrons (LEEs). LEEs induce DNA strand breaks at specific energies (resonances) via dissociative electron attachment (DEA). Although halogenated nucleobases show intense DEA resonances at various electron energies in the gas phase, it is inherently difficult to investigate the influence of halogenated nucleobases on the actual DNA strand breakage over a broad range of electron energies in which DEA can take place (< 12 eV)...
July 3, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28664329/in-type-2-diabetes-subjects-trabecular-bone-score-is-better-associated-with-carotid-intima-media-thickness-than-bmd
#13
Carla Caffarelli, Amalia Giambelluca, Viola Ghini, Valentina Francolini, Maria Dea Tomai Pitinca, Ranuccio Nuti, Stefano Gonnelli
Literature data reported that in elderly subjects, carotid intima-media thickness (IMT) was negatively associated with bone mineral density (BMD). Paradoxically, type-2 diabetes (T2DM) patients, despite having higher BMD, present an increased risk of fragility fractures and cardiovascular complications. Some studies have reported trabecular bone score (TBS), an index of trabecular bone quality, as possibly being reduced in T2DM. This study aimed to evaluate whether in T2DM subjects TBS was better associated with IMT with respect to BMD...
June 29, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28662180/kai-1-and-kai-2-characterization-of-these-dog-erythrocyte-antigens-by-monoclonal-antibodies
#14
Jae Ho Lee, Urs Giger, Hee Young Kim
Dog Erythrocyte Antigens (DEA) have thus far been found by sensitizing dogs with canine allogeneic blood and are clinically important regarding blood transfusion incompatibilities, but remain poorly defined. The goals of this study were to discover and characterize two DEAs, named as Kai 1 and Kai 2. The monoclonal antibodies were produced by mouse hybridoma techniques and examined by ELISA isotyping, immunoblotting, and affinity chromatography. Canine blood samples were typed and the development of alloantibodies was examined in transfused dogs...
2017: PloS One
https://www.readbyqxmd.com/read/28647263/a-zero-valent-iron-and-organic-matter-mixture-enhances-herbicide-and-herbicide-degradation-product-removal-in-subsurface-waters
#15
Kaisa Kerminen, Ville Salovaara, Merja Hannele Kontro
The pesticide atrazine, its degradation products, and 2,6-dichlorobenzamide (BAM) are persistent in groundwater environment. We studied whether their dissipation can be enhanced with a mixture of a complex carbon source and zero-valent iron (ZVI) called EHC®. The application rates were 1.0% and 2.0% (by weight) in subsurface sediments slurries (atrazine 30mg/L), and 2.0% in 1.5m pilot-scale sediment columns with groundwater flowing through (atrazine 0.08, desethylatrazine DEA 0.03, BAM 0.02μg/L). In the slurries under aerobic conditions, atrazine of 0...
July 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28646089/answer-to-july-2017-photo-quiz
#16
EDITORIAL
Aurore Bousquet, Jean-Baptiste Souraud, Audrey Mérens, Dea Garcia-Hermoso, Anne-Claire Fougerousse
No abstract text is available yet for this article.
July 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28646086/photo-quiz-a-25-year-old-male-with-chronic-firm-mass-of-the-foot
#17
EDITORIAL
Aurore Bousquet, Jean-Baptiste Souraud, Audrey Mérens, Dea Garcia-Hermoso, Anne-Claire Fougerousse
No abstract text is available yet for this article.
July 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28641073/gonorrhoea-testing-and-positivity-in-non-remote-aboriginal-community-controlled-health-services
#18
Mary Ellen Harrod, Sophia Couzos, James Ward, Mark Saunders, Basil Donovan, Belinda Hammond, Dea Delaney-Thiele, Mary Belfrage, Sid Williams, Lucy Watchirs Smith, John M Kaldor
Background: Gonorrhoea occurs at high levels in young Aboriginal and Torres Strait Islander people living in remote communities, but there are limited data on urban and regional settings. An analysis was undertaken of gonorrhoea testing and positivity at four non-remote Aboriginal Community Controlled Health Services participating in a collaborative research network. Methods: This was a retrospective analysis of clinical encounter data derived from electronic medical records at participating services. Data were extracted using the GRHANITE program for all patients aged 15-54 years from 2009 to 2013...
June 22, 2017: Sexual Health
https://www.readbyqxmd.com/read/28639650/mechanisms-of-h-and-co-loss-from-the-uracil-nucleobase-following-low-energy-electron-irradiation
#19
Mark A Fennimore, Tolga N V Karsili, Spiridoula Matsika
Ionising radiation in cells generates secondary low energy electrons (LEEs) which can induce biomolecular damage when incident upon a particular biomolecule. Notable biomolecules include those contained within double-stranded DNA and RNA helices, which upon exposure to LEEs, may form reactive intermediate products that show detriment to their specific structures and functions. Such damaging processes are understood to proceed via dissociative electron attachment (DEA). Using anion resonance stabilisation methods, coupled to state-of-the-art electronic structure methods, and reaction path mapping, the work presented herein highlights the detailed mechanisms associated with molecular elimination of CO and H from the uracil nucleobase following LEE irradiation - providing a rationale for earlier experiments...
June 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28634925/technical-efficiency-of-selected-hospitals-in-eastern-ethiopia
#20
Murad Ali, Megersa Debela, Tewfik Bamud
This study examines the relative technical efficiency of 12 hospitals in Eastern Ethiopia. Using six-year-round panel data for the period between 2007/08 and 2012/13, this study examines the technical efficiency, total factor productivity, and determinants of the technical inefficiency of hospitals. Data envelopment analysis (DEA) and DEA- based Malmquist productivity index used to estimate relative technical efficiency, scale efficiency, and total factor productivity index of hospitals. Tobit model used to examine the determinants of the technical inefficiency of hospitals...
December 2017: Health Economics Review
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