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introduction to the diagnosis and classification of monocytic

https://read.qxmd.com/read/33183116/monitoring-immunomodulation-in-patients-with-sepsis
#1
JOURNAL ARTICLE
Evdoxia Kyriazopoulou, Evangelos J Giamarellos-Bourboulis
Introduction This review aims to summarize current progress of the last ten years in the development of biomarkers used for classifying the immune response of the septic host and for monitoring the efficacy of the applied adjunctive immunotherapy. Areas covered An extensive search of the literature was performed. In this review the authors discuss available biomarkers of host immune response in sepsis towards two directions; immunosuppression and hyperinflammation. Ferritin, sCD163, sIL-2ra and IL-18 may help in the diagnosis of macrophage activation syndrome (MAS) complicating sepsis whereas lymphopenia, decreased HLA-DR expression on monocytes, overexpression of Programmed cell death protein-1 (PD-1)/Programmed death-ligand 1 (PD-L1) and IL-10 are indicators of sepsis-induced immunosuppression...
November 12, 2020: Expert Review of Molecular Diagnostics
https://read.qxmd.com/read/26282340/introduction-to-the-diagnosis-and-classification-of-monocytic-lineage-leukemias-by-flow-cytometry
#2
REVIEW
Sergio Matarraz, Julia Almeida, Juan Flores-Montero, Quentin Lécrevisse, Valentina Guerri, Antonio López, Susana Bárrena, Vincent H J Van Der Velden, Jeroen G Te Marvelde, Jacques J M Van Dongen, Alberto Orfao
Despite diagnostic criteria are currently available for the distinct subtypes of monocytic-lineage neoplasias, a number of partially overlapping features still remain evident, which may hamper their differential diagnosis. An accurate identification and characterization of monocytic cells is of major relevance for the diagnosis and classification of these neoplasias. In this regard, as compared to other conventional techniques, flow cytometry has shown the highest sensitivity for detection of early monocytic commitment of (normal and neoplastic) bone marrow CD34+ hematopoietic precursors as well as of monocytic aberrations and maturation blockades, which are frequently associated with clonal myeloid disorders...
May 2017: Cytometry. Part B, Clinical Cytometry
https://read.qxmd.com/read/9301644/myelodysplasia-and-the-leukemias
#3
REVIEW
P Jacobs
The armistice after World War II marked the beginning of an era that was to last to the end of the present century. It was an era in which many changes in medicine and nursing combined to alter the entire philosophy of managing malignant disease. More specifically, the fluid-phase tumors, which comprise myelodysplasia and the leukemias, were singled out for special attention. First there was the ease with which blood and bone marrow could be sampled, making serial investigations simple and practical. Second, cytotoxic drugs became available ranging from nitrogen mustard through cytosine arabinoside, the anthracycline antibiotics, and the epi-podophyllotoxins...
August 1997: Disease-a-month: DM
https://read.qxmd.com/read/6296379/-radiological-aspects-of-malignant-histiocytic-pathology
#4
JOURNAL ARTICLE
V Turculet
The histiocyte, macrophage of tissue monocyte is a cell of the mononuclear system. At the moment several different types of classification of the malignant histiocytic pathology are use. Seven cases of this pathology are documented: two cases of malignant histiocytosis, two cases of malignant histiocytic lymphoma, two cases of malignant histiocytoma of soft tissue and one malignant histiocytic tumor of bone. The purpose of this study is to analyse the usefulness the roentgenologic methods: conventional radiography, radionuclide scanning, computed tomography, sonography, xeroradiography, angiography...
November 1982: Journal de Radiologie
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