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controlling blood sugar levels

Bruna Andrade Aguiar, Dailiany Orechio, Paula Fratini, Ana Claudia Oliveira Carreira, Patricia Castelucci, Maria Angelica Miglino
The incidence of diabetes mellitus in dogs is increasing in recent years, mainly because of genetic and/or environmental factors, including endocrine disorders (like in humans); failure of suitable control of blood sugar levels, which triggers hyperglycemia; glycosuria and weight loss, which demands the development of innovative treatments to cure or treat this complex disease in dogs. The present study established for the first time a protocol to obtain and characterize cells derived from pancreas of canine fetuses...
October 17, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
Leyla Saeidi, Hamid Ghaedi, Mirsaber Sadatamini, Rouhollah Vahabpour, Ali Rahimipour, Mehrnoosh Shanaki, Zahra Mansoori, Faranak Kazerouni
Long non-coding RNAs (LncRNAs) are non-coding RNAs. The potential roles of lncRNAs in type 2 diabetes mellitus (T2DM) are not well-known. In this study, we aim to assess the expression levels of LY86-AS1 and HCG27_201 in T2DM patients and a healthy control group. We obtained whole blood and serum samples from 100 T2DM and 100 non-diabetic subjects. Peripheral blood mononuclear cells (PBMCs) were extracted from whole blood samples using Ficoll. Total RNA was isolated from PBMCs obtained from patients with type 2 diabetes mellitus and healthy control individuals using TRIzol LS reagent (GeneAll Biotechnology Co...
October 16, 2018: Molecular Biology Reports
Bahar Azemati, Roya Kelishadi, Zeinab Ahadi, Gita Shafiee, MajZoubeh Taheri, Hasan Ziaodini, Mostafa Qorbani, Ramin Heshmat
AIMS: Only a few studies have attempted to assess the relationship between junk food consumption and cardiometabolic risk factors in Iranian children and adolescents; therefore, the aim of our study was to determine the association between junk food intake and cardiometabolic risk factors in this population. STUDY DESIGN: This is a cross-sectional study. METHODS: A total of 14,400 students were selected from 30 provinces of Iran using multistage, stratified cluster sampling method...
October 11, 2018: Eating and Weight Disorders: EWD
Kara Stoudt, Sanjay Chawla
Stress hyperglycemia is the transient increase in blood glucose as a result of complex hormonal changes that occur during critical illness. It has been described in the critically ill for nearly 200 years; patient harm, including increases in morbidity, mortality, and lengths of stay, has been associated with hyperglycemia, hypoglycemia, and glucose variability. However, there remains a contentious debate regarding the optimal glucose ranges for this population, most notably within the past 15 years. Recent landmark clinical trials have dramatically changed the treatment of stress hyperglycemia in the intensive care unit (ICU)...
October 11, 2018: Journal of Intensive Care Medicine
Julie Dupas, Annie Feray, Anthony Guernec, Morgane Pengam, Manon Inizan, François Guerrero, Jacques Mansourati, Christelle Goanvec
Background: Metabolic Syndrom has become a public health problem. It mainly results from the increased consumption of fat and sugar. In this context, the benefits of personalized moderate exercise training were investigated on a metabolic syndrome male wistar rat model food with fructose drinking water (20-25% w / v ). Different markers including body weight, metabolic measurements, blood biochemistry related to metabolic syndrome complications have been evaluated. Methods: Male Wistar rats were randomly allocated to 4 groups: control (sedentary (C, n  = 8) and exercise trained (Ex, n = 8)), fructose fed (sedentary (FF, n = 8) and exercise trained fructose fed rats (ExFF, n  = 10))...
2018: Nutrition & Metabolism
Suleiman Furmli, Rami Elmasry, Megan Ramos, Jason Fung
This case series documents three patients referred to the Intensive Dietary Management clinic in Toronto, Canada, for insulin-dependent type 2 diabetes. It demonstrates the effectiveness of therapeutic fasting to reverse their insulin resistance, resulting in cessation of insulin therapy while maintaining control of their blood sugars. In addition, these patients were also able to lose significant amounts of body weight, reduce their waist circumference and also reduce their glycated haemoglobin level.
October 9, 2018: BMJ Case Reports
Manjitpal Singh, Vimal Upreti, Yashpal Singh, Anand S Kannapur, Monish Nakra, Narendra Kotwal
Background: Evidence suggests a role of glycemic variability in intensive care unit (ICU) mortality. Objective: To assess effect of glycemic variability and ICU/in-hospital mortality. Design: Prospective, observational study. Setting: A 20-bedded medical/surgical ICU in a tertiary care hospital. Patients: Critically ill patients requiring life-support measures admitted to the ICU between November 1, 2015 and December 30, 2016 with hyperglycemia [random blood sugar (RBS) ≥200 mg%] and sequential organ failure assessment (SOFA) scores ≤9...
September 2018: Indian Journal of Endocrinology and Metabolism
B P Amrith, Prayas Sethi, Manish Soneja, Naval Vikram, Arvind Kumar, Praveen Aggarwal, Viveka P Jyotsna, R M Pandey, Naveet Wig
Background: Hyperglycemia is a common comorbidity in hospitalized patients and may add to adverse outcomes. Various associations have issued guidelines for optimal management of hyperglycemia in ill patients. This study aims to assess the adherence to current guidelines in inpatient setting and the impact of educational interventions on the improvement in adherence to guidelines as well as its effect on the level of blood sugar control and patient outcomes. Materials and Methods: It was a quasi-experimental pretest and posttest study and was done in three phases, viz...
September 2018: Indian Journal of Endocrinology and Metabolism
Young Chul Suh, Beatriz Hatse Kushida-Contreras, Hyun Suk, Peter Suh, Ho Seung Lee, Woo Je Lee, Seung Hwan Lee, Joon Pio Hong
BACKGROUND: The benefits of total transmetatarsal amputation (TMA) over higher level amputation are well known. However, there are no studies evaluating the effects of first or the first two ray sparing transmetatarsal amputation with flap coverage. We evaluated this approach in regards to functional outcome and to identify long-term complications. MATERIAL AND METHOD: Retrospective data of 59 patients were evaluated according to their surgical method. Complete TMA with free flap reconstruction was designated as group TMA with 27 patients and first or first two rays preserving TMA with free flap reconstruction was designated as group Ray with 32 patients...
October 1, 2018: Plastic and Reconstructive Surgery
Keith R Martin, Lacey Burrell, Jennifer Bopp
Subclinical inflammation is frequently noted in chronic diseases such as diabetes, cardiovascular disease (CVD) and obesity. Accumulating epidemiological evidence demonstrates that diets rich in vegetables and fruits, e.g., cherries, may significantly reduce the risk of chronic disease, in part, via antioxidant and anti-inflammatory activities. In this randomized, placebo-controlled crossover study, we recruited 10 at-risk participants (38.1 ± 12.5 years; 8 females, 2 males) with BMI >25.0 kg m-2 (32.2 ± 4...
October 17, 2018: Food & Function
Neel Shimpi, Ingrid Glurich, Dixie Schroeder, Callahan Katrak, Po-Huang Chyou, Amit Acharya
This cross-sectional study sought to assess the current awareness, knowledge, and behavior regarding diabetes mellitus (DM) and periodontal disease (PD) association among a convenience sample of patients from a large Wisconsin-based integrated medical-dental health care organization serving largely rurally based communities. An anonymous 10-question survey was distributed at regional medical and dental centers of dental and medical clinics of a single health care institution over a 4-week period, to achieve a cross-sectional sampling of patients aged 18 to 80 years...
September 21, 2018: Health Promotion Practice
Mohamed F A Farghly, Enas A M Ahmad, Mahmoud Alagawany, Mohamed E Abd El-Hack, Reham A M Ali, Shaaban S Elnesr, Ayman E Taha, Ayman S Salah
The management practices implemented by the poultry sector as using some nutritional additives in the early stage of a bird's life can potentially detect other challenges to production development in the poultry farms. Many potential supplements can be included in the early feeding as which are added to drinking water. In this study, 180 1-day-old chicks were randomly distributed into six groups to investigate the use of some nutritional supplements in drinking water of growing turkeys during 1st month of age and their effect on growth performance, carcass traits, meat quality, leg problems, blood profile and oxidative status...
September 20, 2018: Journal of Animal Physiology and Animal Nutrition
Anika Nier, Annette Brandt, Ina Barbara Conzelmann, Yelda Özel, Ina Bergheim
The role of nutrition and diet in the development of non-alcoholic fatty liver disease (NAFLD) is still not fully understood. In the present study, we determined if dietary pattern and markers of intestinal permeability differ between overweight children with and without NAFLD. In addition, in a feasibility study, we assessed the effect of a moderate dietary intervention only focusing on nutrients identified to differ between groups on markers of intestinal barrier function and health status. Anthropometric data, dietary intake, metabolic parameters, and markers of inflammation, as well as of intestinal permeability, were assessed in overweight children ( n = 89, aged 5⁻9) and normal-weight healthy controls ( n = 36, aged 5⁻9)...
September 19, 2018: Nutrients
Sarah V Liu, Lori B Moore, Tanya M Halliday, A Hope Jahren, Jyoti Savla, Valisa E Hedrick, Elaina L Marinik, Brenda M Davy
BACKGROUND: Consumption of added sugars (AS) and sugar-sweetened beverages (SSB) may adversely affect adolescents' weight and cardiovascular disease risk. Reliance on self-reported dietary assessment methods is a common research limitation, which could be overcome by dietary intake biomarkers. AIM: The investigation was a proof-of-concept study to evaluate the proposed carbon isotope ratio (δ13 C) biomarker of AS intake in adolescents, using a controlled feeding design...
September 20, 2018: Nutrition and Health
Anping Xu, Jian Sun, Jie Li, Weidong Chen, Ruoyang Zheng, Zhonghou Han, Ling Ji
BACKGROUND: HbA1c is the standard bio-marker for glycemic control in patients with diabetes. Here, we report a α-globin chain variant and evaluate its effect on HbA1c measurements. METHODS: A 21-year-old female was suspected of harboring a hemoglobin variant following HbA1c measurement during a routine examination using Variant II Turbo 2.0 (Bio-Rad). An oral glucose tolerance test was performed using an AU5800 clinical chemistry system (Beckman Coulter). HbA1c was reanalyzed using D10 (Bio-Rad), Capillarys 2 Flex Piercing (Sebia), and Premier Hb9210 (Trinity Biotech)...
September 17, 2018: Journal of Clinical Laboratory Analysis
Asieh Zarvasi, Ali Ansari Jaberi, Tayebeh Negahban Bonabi, Mahnaz Tashakori
Background: Uncontrolled symptoms of diabetes can lead to irreparable damage to vital organs. Despite the global trend towards the use of complementary alternative therapies, few studies have evaluated the effectiveness of self-acupressure in diabetes patients. Objective: The aim of this study was to determine the effect of self-acupressure on FBS and insulin level in type 2 diabetes patients. Methods: This randomized clinical trial was performed from September 2016 to February 2017...
August 2018: Electronic Physician
Essam Abdel-Sattar, Eman T Mehanna, Sabah H El-Ghaiesh, Hala M F Mohammad, Hanan A Elgendy, Sawsan A Zaitone
Background and purpose: Russelioside B (RB) is a pregnane glycoside obtained from Caralluma quadrangula ; a herb with antidiabetic, anti-inflammatory, and antihyperlipidemic activities. The present experiment tested the possible role of RB in controlling weight gain in rats fed on high fat (HF) diet. Methods: RB was separated from the n-butanol fraction of the crude methanolic extract by chromatographic separation on a Si gel column according to the procedures described previously. The experiment of the biological assessment of RB used 32 male Wistar rats (4 groups, n = 8)...
2018: Frontiers in Pharmacology
Farhana Rizwan, Harun Ur Rashid, Saquiba Yesmine, Forhad Monjur, Tapan Kumar Chatterjee
Background: Stevia, Stevia rebaudiana (Bertoni), has become an important economic plant for its commercial use as a sweetener. Stevia plays a significant role in the healthcare practice of different cultures and in population. Previous animal and clinical studies demonstrated the efficacy of Stevia against chronic diseases like diabetes and hypertension. This study aimed to investigate the beneficial effect of Stevia in chronic kidney disease (CKD) patients after three (3) months of treatment along with the conventional antihypertensive and anti diabetic medications...
December 2018: Contemporary Clinical Trials Communications
Alireza Askari, Ali Khani Jeihooni, Seyyed Mansour Kashfi, Atefeh Marzban, Zahra Khiyali
Background: Diabetes is the most common disease related to metabolism disorders. Today, diabetes in the elderly is one of the major epidemics of the century. This study aimed to investigate the effect of nutrition and jogging-based Belief, Attitude, Subjective Norm, and Enabling Factors (BASNEF) model in changes in metabolic parameters that performed in elderly patients with type II diabetes in Fasa city. Methods: This study was a randomized clinical trial on 108 elderly patients with type II diabetes (54 patients in the experimental group and 54 in control group) referred to the diabetes center in Fasa City, Fars Province, Iran, in 2016...
2018: International Journal of Preventive Medicine
Zahra Abbaspoor, Anis Amani, Poorandokht Afshari, Sima Jafarirad
Introduction Gestational diabetes is increasing in developed and developing countries. This study aimed to evaluate the effect of SMS messaging on the self-care among pre-diabetic pregnant women. Methods This randomized controlled trial conducted on 100 pre-diabetic pregnant women referred to Ahvaz Health Centers, Iran, Sep to Dec, 2016. Women were randomly assigned into the face to face education group and short message systems in addition to the face to face education group. Self-care variables were compared between the groups...
September 7, 2018: Journal of Telemedicine and Telecare
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