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https://www.readbyqxmd.com/read/29322617/preview-prevention-of-diabetes-through-lifestyle-intervention-in-a-multicentre-study-in-europe-in-children-10-17y-design-methods-and-baseline-results
#1
Elke Dorenbos, Mathijs Drummen, Jesse Rijks, Tanja Adam, Pauline Stouthart, J Alfredo Martínez, Santiago Navas-Carretero, Gareth Stratton, Nils Swindell, Mikael Fogelholm, Anne Raben, Margriet Westerterp-Plantenga, Anita Vreugdenhil
Insulin resistance (IR) in adolescence is associated with T2DM. The PREVIEW study assesses the effectiveness of a high-protein, low-glycaemic index diet and moderate-protein, moderate-glycaemic index diet to decrease IR in insulin resistant children with overweight/obesity. Inclusion criteria were age 10-17y, HOMA-IR≥2.0 and overweight/obesity. In 126 children (13.6±2.2y, BMI z-score 3.04±0.66, HOMA-IR 3.48±2.28) anthropometrics, fat mass percentage (FM%), metabolic parameters, physical activity, food intake and sleep were measured...
January 11, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29308639/s-layer-protein-for-resistive-switching-and-flexible-nonvolatile-memory-device
#2
Akshay Moudgil, Neeti Kalyani, Gaurav Sinsinbar, Samaresh Das, Prashant Mishra
In this work, flexible resistive switching memory device consisting of S-layer protein is demonstrated for the first time. This novel device (Al/Slp/ITO/PET) based on simple and easy fabrication method is capable of bistable - LRS (low resistive state) and HRS (high resistive state) - switching. This device exhibits bistable memory behavior with stability and long retention time (>4x103 s), stable up to 500 cycle endurance test and significant HRS/LRS ratio. The device possesses consistent switching performance for more than 100 times bending, corresponding to desired applicability for biocompatible wearable electronics...
January 8, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29305652/-doping-with-illegal-and-legal-substances-in-old-age
#3
REVIEW
Thomas Münzer
The number of old persons who participate in sports and can even achieve peak performances is increasing steadily. Normal aging, however, is associated with decreased muscle strength and a decline in cardiovascular endurance even in those persons who regularly participate in sports. Thus, it seems obvious to impact on muscle mass and muscle strength by using anabolic substances. The number of older persons who illegally use doping substances is currently unknown. Besides classical anabolic drugs, other proteins and amino acids are used to impact on muscle mass or strength...
January 5, 2018: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/29284921/splenic-localization-of-primary-hydatid-cyst-in-a-27-year-old-sportsman-treated-by-pair-technique-imaging-anatomy-assessment
#4
Dzenan Jahic, Eldan Kapur, Edin Begic, Enver Zerem
Introduction: In this paper, we report our experience with a case of primary hydatid cyst involving only the spleen in a 27-year-old sportsman treated by PAIR technique. Case Report: Five years before, a 27-year-old handball player being admitted to our hospital, it was detected the cyst in his spleen which size was 35 x 30 mm in diameter, by abdominal ultrasound during a systematic examination. There was no pain or any other symptoms at that time. Tests on the presence of echinococcus cysts were negative...
December 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/29282165/in-vitro-effects-of-sports-and-energy-drinks-on-streptococcus-mutans-biofilm-formation-and-metabolic-activity
#5
LaQuia A Vinson, Amy K Goodlett, Ruijie Huang, George J Eckert, Richard L Gregory
PURPOSE: Sports and energy drinks are being increasingly consumed and contain large amounts of sugars, which are known to increase Streptococcus mutans biofilm formation and metabolic activity. The purpose of this in vitro study was to investigate the effects of sports and energy drinks on S. mutans biofilm formation and metabolic activity. METHODS: S. mutans UA159 was cultured with and without a dilution (1:3 ratio) of a variety of sports and energy drinks in bacterial media for 24 hours...
September 15, 2017: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/29280665/use-of-nutritional-supplements-and-ergogenic-aids-in-professional-tennis-players
#6
Álvaro López-Samanes, Víctor Moreno-Pérez, Mark S Kovacs, Jesús G Pallarés, Ricardo Mora-Rodríguez, Juan F Ortega
INTRODUCTION: Nutritional supplements and ergogenic aids (NS&EA) are used between training/matches with the goal of enhancing tennis performance. Scientific literature about prevalence and use of NS&EA in professional tennis players is scarce. OBJECTIVE: The aim of the study was to describe the NS&EA used by professional tennis players during a season. METHODS: Using a validated self-administered questionnaire, 62 professional male and 9 professional female tennis players (11% in their gender specific top 100 tennis world ranking (i...
November 17, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29226558/detection-of-the-human-anti-actrii-antibody-bimagrumab-in-serum-by-means-of-affinity-purification-tryptic-digestion-and-lc-hrms
#7
Katja Walpurgis, Andreas Thomas, Frank Dellanna, Wilhelm Schänzer, Mario Thevis
PURPOSE: Inhibitors of the ActRII signaling pathways represent promising therapeutics for the treatment of muscular diseases, but also pose risks as performance-enhancing agents in sports. Bimagrumab is a human anti-ActRII antibody which was found to increase muscle mass and function by blocking ActRII signaling. As it has considerable potential for being misused as doping agent in sports, the aim of this study was to develop a mass spectrometric detection assay for doping control serum samples...
December 11, 2017: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/29198760/impact-of-long-distance-rowing-on-biological-health-a-pilot-study
#8
Miguel A Frias, Julien Virzi, Olivier Golaz, Baris Gencer, François Mach, Nicolas Vuilleumier
OBJECTIVES: To determine the impact of long distance rowing (160km, nonstop) on standard biological parameters and to study the relation between inflammation, myocardial necrosis, lipid profile, heart rate and energy expenditure. METHODS: Electrolytes, lipid profile, C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), procalcitonin (PCT), high-sensitive troponin T (hs-cTnT), and N-terminal pro-brain natriuretic peptide (NT-proBNP), were measured on non-fasting venous blood samples collected 8h before and after the rowing race on five healthy competitors...
November 30, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/29198116/characterization-and-detection-of-epo-fc-fusion-proteins-using-lc-ms
#9
Natalia V Mesonzhnik, Pavel V V Postnikov, Svetlana A Appolonova, Grigory I Krotov
EPO-Fc fusion proteins are potential drug candidates that have been designed for the treatment of anaemia in humans by stimulating erythrocyte production. Such compounds can be considered performance enhancing agents that may be used by athletes in endurance sports. This study describes the primary structure of commercially available EPO-Fc based on comprehensive liquid-chromatography coupled with mass-spectrometry (LC-MS) analysis. A bottom-up approach and the intact molecular weight (MW) measurement of deglycosylated protein and its IdeS proteolytic fractions was used to determine the amino acid sequence of EPO-Fc...
December 2, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/29160809/evaluation-of-dietary-intakes-and-supplement-use-in-paralympic-athletes
#10
Robyn F Madden, Jane Shearer, Jill A Parnell
Dietary intakes and supplement use in Paralympic athletes remains largely unexplored, and specialized recommendations are lacking. The aim of this study was to evaluate nutrient intakes and supplement use in high-performance athletes with physical disabilities using three-day food records and a validated dietary supplement use questionnaire. A secondary aim examined gender differences in nutrient and supplement intakes. Male (n = 18) and female (n = 22) athletes were recruited from nine Paralympic sports through sporting organizations, coaches, and social media...
November 21, 2017: Nutrients
https://www.readbyqxmd.com/read/29158725/nutritional-supplement-practices-of-professional-ugandan-athletes-a-cross-sectional-study
#11
Haruna Muwonge, Robert Zavuga, Peninnah Aligawesa Kabenge, Timothy Makubuya
Background: The use of nutritional supplements (NS) places athletes at great risk for inadvertent doping. Due to the paucity of data on supplement use, this study aimed to determine the proportion of Ugandan athletes using nutritional supplements and to investigate the athletes' motivation to use these supplements. Methods: A cross-sectional study was conducted in which an interviewer-administered questionnaire was used to collect data from 359 professional athletes participating in individual (boxing, cycling, athletics) and team (basketball, rugby, football, netball, and volleyball) sports...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29156929/-role-of-the-egg-in-the-diet-of-athletes-and-physically-active-people
#12
Ana M López Sobaler, Aránzazu Aparicio Vizuete, Rosa M Ortega
The practice of sport and medium-high intensity exercise increases the needs of energy and nutrients. Proper nutrition is very important for reaching the maximum performance, reducing the risk of injury, and ensuring the best recovery. It must also ensure the achievement of optimum nutritional status and prevent health problems at the present and in the future time. Eggs are a very nutritious food that can help athletes to achieve a correct diet. It contains proteins of high quality and bioavailability, a profile of fatty acids very favorable from the cardiovascular point of view, and vitamins and minerals involved in energy and protein metabolism, in defense against oxidative stress and inflammation, in cell growth and tissue repair...
October 15, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29153178/a-100-year-review-the-production-of-fluid-market-milk
#13
David M Barbano
During the first 100 years of the Journal of Dairy Science, dairy foods and dairy production dairy scientists have partnered to publish new data and research results that have fostered the development of new knowledge. This knowledge has been the underpinning of both the commercial development of the fluid milk processing industry and regulations and marketing policies for the benefit of dairy farmers, processors, and consumers. During the first 50 years, most of the focus was on producing and delivering high-quality raw milk to factories and improving the shelf life of pasteurized fluid milk...
December 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29130715/relationship-of-long-term-macronutrients-intake-on-anabolic-catabolic-hormones-in-female-elite-volleyball-players
#14
Juan Mielgo Ayuso, Michael C Zourdos, Aritz Urdampilleta, Julio Calleja González, Jesús Seco, Alfredo Córdova
INTRODUCTION: Specific macronutrient distribution and training can alter acute and chronic hormone behavior and, subsequently, sport performance. OBJECTIVE: The main aim was to examine relationships between dietary intake and anabolic/catabolic hormone response in elite female volleyball players during a 29-week season. METHODS: Twenty-two elite female volleyballers (26.4 ± 5.6 years; 178 ± 9 cm; 67.1 ± 7.5 kg) had dietary intake (seven-day dietary recall and food frequency questionnaire), blood concentration of anabolic/catabolic hormones concentration, physical performance, and body composition assessed at four time points: a) T1: baseline/pre-testing; b) T2: eleven weeks after T1; c) T3: ten weeks after T2; and d) T4: eight weeks after T3...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29127759/is-irisin-the-new-player-in-exercise-induced-adaptations-or-not-a-2017-update
#15
REVIEW
Ioannis G Fatouros
Irisin is produced by a proteolytic cleavage of fibronectin type III domain-containing protein 5 (FNDC5) and has emerged as a potential mediator of exercise-induced energy metabolism. The purpose of this study was to review the results of studies that investigated irisin responses to acute and chronic exercise and provide an update. A comprehensive search in the databases of MEDLINE was performed (74 exercise studies). The focus of the analysis was on data concerning FNDC5 mRNA expression in skeletal muscle and circulating irisin concentration relatively to exercise mode, intensity, frequency and duration and the characteristics of the sample used...
November 11, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29126218/libra-wa-a-web-application-for-ligand-binding-site-detection-and-protein-function-recognition
#16
Daniele Toti, Viet Hung Le, Valentina Tortosa, Valentina Brandi, Fabio Polticelli
Summary: Recently, LIBRA, a tool for active/ligand binding site prediction, was described. LIBRA's effectiveness was comparable to similar state-of-the-art tools; however, its scoring scheme, output presentation, dependence on local resources and overall convenience were amenable to improvements. To solve these issues, LIBRA-WA, a web application based on an improved LIBRA engine, has been developed, featuring a novel scoring scheme consistently improving LIBRA's performance, and a refined algorithm that can identify binding sites hosted at the interface between different subunits...
November 6, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29116863/hypothermia-promotes-cell-protective-and-chondroprotective-effects-after-blunt-cartilage-trauma
#17
Jana Riegger, Madeleine Zimmermann, Helga Joos, Thomas Kappe, Rolf E Brenner
BACKGROUND: Cryotherapy is routinely administered after sports injuries of synovial joints. Although positive clinical effects on periarticular swelling and pain have been described, the effects on the cell biological activities of cartilage and synovial cells remain largely unknown so far. HYPOTHESIS: Local hypothermia alleviates synovial reactions and prevents chondrocyte death as well as cartilage destructive processes after blunt cartilage trauma. STUDY DESIGN: Controlled laboratory study...
November 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29104456/sports-and-hdl-quality-reflected-by-serum-amyloid-a-and-surfactant-protein-b
#18
Michael Sponder, Chantal Kopecky, Ioana-Alexandra Campean, Michael Emich, Monika Fritzer-Szekeres, Brigitte Litschauer, Senta Graf, Marcus D Säemann, Jeanette Strametz-Juranek
Background: The aim of this prospective study was to investigate the influence of long-term physical activity on HDL quality, reflected by serum amyloid A (SAA) and surfactant protein B (SPB). Methods and results: 109 healthy subjects were recruited, 98 completed the study. Participants perform within the calculated training pulse for 8 months. The performance gain was measured/quantified by bicycle stress tests at the beginning and end of the observation period. SAA and SPB were measured at baseline and after 4 and 8 months by ELISA...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29096980/arthroscopic-management-of-septic-arthritis-of-the-native-shoulder-a-systematic-review
#19
REVIEW
Muzammil Memon, Jeffrey Kay, Lydia Ginsberg, Darren de Sa, Nicole Simunovic, Kristian Samuelsson, George S Athwal, Olufemi R Ayeni
PURPOSE: To investigate arthroscopic management of native shoulder joint septic arthritis-specifically, indications, patient outcomes, and complications. METHODS: PubMed, MEDLINE, and Embase were used to search the literature, and data abstraction was performed independently and in duplicate. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) checklist guided reporting and data abstraction. The quality of all included studies was assessed with the Methodological Index for Non-randomized Studies (MINORS) criteria...
October 30, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29073820/acute-changes-in-plasma-total-tau-levels-are-independent-of-subconcussive-head-impacts-in-college-football-players
#20
Keisuke Kawata, Leah H Rubin, Leroy Wesley, Jong Lee, Thomas Sim, Masahiro Takahagi, Al Bellamy, Ryan Tierney, Dianne Langford
Athletes in contact sports sustain repetitive subconcussive head impacts in a brief window, yet neurophysiological sequelae from repetitive subconcussion remain unclear. This prospective longitudinal study examined a relationship between changes in plasma Tau protein levels and subconcussive impact kinematic data in 23 Division-I collegiate football players during a series of pre-season practices. Plasma measures for Tau and S100β proteins, symptom scores, and near point of convergence were obtained at preseason baseline and pre-post practices...
October 26, 2017: Journal of Neurotrauma
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