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History of pediatrics

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https://www.readbyqxmd.com/read/29785658/incidence-and-risk-factors-for-positive-urine-culture-at-the-time-of-pediatric-urologic-surgery
#1
Michael A Maccini, David J Chalmers, Vijaya M Vemulakonda, Jeffrey B Campbell
PURPOSE: Urinary tract infections are relatively common in pediatric patients. Unrecognized bacteriuria at the time of urologic surgery puts patients at increased risk for perioperative complications. Many pediatric urologists obtain preoperative or intraoperative urine cultures prior to surgery, but data are lacking regarding rates and risk factors for positive intraoperative urine cultures. We conducted a retrospective cohort study of patients undergoing pediatric urologic surgery to examine factors associated with positive intraoperative urine cultures...
May 21, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29784471/rotavirus-gastroenteritis-surveillance-in-azerbaijan-2011-2016
#2
Nazifa Mursalova, Nazim Shugayev, Javahir Suleymanova, Danni S Daniels, Annemarie Wasley, Adam L Cohen, Negar Aliabadi
INTRODUCTION: Rotavirus is a leading cause of acute gastroenteritis and mortality among children worldwide but data describing rotavirus disease in Azerbaijan are lacking. This analysis describes the rotavirus disease burden in Baku, the largest city in Azerbaijan. METHODS: We conducted active, prospective, sentinel hospital surveillance with laboratory confirmation for rotavirus among children under 5 years of age hospitalized at a large pediatric hospital in Baku during 2011-2016...
May 18, 2018: Vaccine
https://www.readbyqxmd.com/read/29782992/single-ultra-high-dose-cholecalciferol-to-prevent-vitamin-d-deficiency-in-pediatric-hematopoietic-stem-cell-transplantation
#3
Gregory Wallace, Sonata Jodele, Kasiani C Myers, Christopher E Dandoy, Javier El-Bietar, Adam Nelson, Ashley Teusink-Cross, Pooja Khandelwal, Cynthia Taggart, Catherine M Gordon, Stella M Davies, Jonathan C Howell
BACKGROUND: Vitamin D (vitD) deficiency is prevalent among childhood hematopoietic stem cell transplantation (HSCT) recipients and associated with inferior transplant survival at 100 days after transplantation. Achieving and maintaining therapeutic vitD levels in HSCT recipients is extremely challenging in the first 3-6 months after transplant due to poor compliance in the setting of mucositis, and concomitant use of critical transplant drugs that interfere with vitD absorption. We sought to evaluate the safety and efficacy of a single, ultra-high dose of vitD given prior to childhood HSCT to maintain levels in a therapeutic range during the peri-transplantation period...
May 18, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29779933/-hereditary-optic-neuropathies-in-pediatric-ophthalmology
#4
C Orssaud, M P Robert, D Bremond Gignac
INTRODUCTION: Hereditary optic neuropathies (HON) often begin in adulthood. However, some of them can have an early onset. These may have specific clinical features and natural histories. PATIENTS AND METHODS: Retrospective study of HON patients with onset before the age of 14 years seen in a referral center. In addition to the age of onset, we evaluated the genetic etiology, visual acuity at 15 years, last best corrected visual acuity, optic disc appearance, visual field and extra-ophthalmological manifestations...
May 17, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29779911/piloting-medication-histories-in-a-pediatric-postanesthesia-care-unit
#5
Nathan Lake, Humaira Nawer, Deborah Wagner
PURPOSE: Develop a medication history process for pediatric postanesthesia care unit (PACU) patients to identify discrepancies between home and inpatient medications and prevent medication errors. DESIGN: Pilot an evidence-based practice change to perform PACU medication histories. METHODS: Inpatients or surgical admissions to general care units at a pediatric tertiary care 348-bed hospital ages 2-18 years were included. Parents/guardians were asked about their child's prescription and over-the-counter medications, allergies, and adherence...
May 18, 2018: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29778284/-clinical-and-epidemiological-profile-of-pediatric-uveitis-course-of-inflammatory-uveitis-treated-with-anti-tnf-alpha
#6
D Osswald, A C Rameau, C Speeg-Schatz, J Terzic, A Sauer
INTRODUCTION: Uveitis is the leading cause of acquired childhood blindness with a prevalence of 30 cases per 100,000 inhabitants. There are multiple causes ; nevertheless, there is no standardized etiological assessment. The goal of our study is to define an epidemiological and clinical profile of uveitis diagnosed in a university hospital and their course when treated with anti-tumor necrosis factor (TNF) α. PATIENTS AND METHODS: All cases of uveitis under 18 years old, from 1994 to 2016, were included...
May 16, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29778231/clinical-germline-diagnostic-exome-sequencing-for-hereditary-cancer-findings-within-novel-candidate-genes-are-prevalent
#7
Zöe Powis, Carin R Espenschied, Holly LaDuca, Kelly D Hagman, Tripti Paudyal, Shuwei Li, Hiroto Inaba, Ann Mauer, Katherine L Nathanson, James Knost, Elizabeth C Chao, Sha Tang
Clinical diagnostic exome sequencing (DES) has been effective in diagnosing individuals with suspected genetic conditions; nevertheless little has been described regarding its clinical utility in individuals with a personal and family history of cancer. This study aimed to assess diagnostic yield and clinical characteristics of pediatric and adult patients undergoing germline DES for hereditary cancer. We retrospectively reviewed 2171 patients referred for DES; cases with a personal and/or family history of cancer were further studied...
August 2018: Cancer Genetics
https://www.readbyqxmd.com/read/29778122/provider-language-proficiency-and-decision-making-when-caring-for-limited-english-proficiency-children-and-families
#8
Yolanda N Evans, Sarah A Rafton, Eriberto Michel, Beth E Ebel
OBJECTIVE: To examine associations between self-assessed language ability and provision of clinical care without professional interpretation. METHODS: We conducted an anonymous web-based survey of pediatric residents at a large pediatric training program. Respondents self-rated their language ability, and then reported on their willingness to deliver clinical care without professional interpretation in standardized clinical scenarios. RESULTS: All pediatric residents completed the survey (n=81; 100%)...
June 2018: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29777892/surgically-treated-de-novo-cervico-medullary-arachnoid-cyst-in-a-symptomatic-adult-patient
#9
William Clifton, Gazanfar Rahmathulla, Kourosh Tavanaiepour, Dunbar Alcindor, George Jakubek, Daryoush Tavanaiepour
Arachnoid cysts are a relatively common finding in adult patients, especially with the advent of advanced imaging techniques. The overall incidence ranges from 1-2%, and the majority are clinically silent1,2 . Arachnoid cysts are postulated to arise by congenital anomalies or trauma1 . De novo formation of arachnoid cysts has been reported, but is exceptionally rare and mostly found in the pediatric population after head trauma3-5 . There have only been two reported cases of symptomatic de novo arachnoid cyst formation in adult patients to date, both with histories of head trauma6,7 ...
May 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29776891/chronic-recurrent-multifocal-osteomyelitis-in-pediatrics-a-diagnostic-challenge
#10
N Roig-Abraham, M Méndez-Hernández, M Martínez-Morillo
Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory disease that presents with aseptic bone inflammation and can be accompanied by multisystemic symptoms. We present the case of a 14-year-old male with a 2-week history of pain located at the tibial metaphysis and fever. X-ray revealed a lytic lesion in the tibial metaphysis. MRI revealed an intramedullary bone lesion with perilesional bone oedema. CT-guided biopsy discounted malignancy and microbiological cultures were negative. The patient's symptoms and fever worsened after the biopsy; therefore antibiotherapy was commenced for a suspected superinfection...
May 15, 2018: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/29776870/historical-bibliometric-analysis-of-the-top-cited-articles-on-vesicoureteral-reflux-1950-2016-and-incorporation-of-a-novel-impact-index
#11
N Fernandez, A Puerto, A Azuero, F O'Kelly, J Hannick, M Rickard, A Kirsch, A Caldamone, M Koyle
INTRODUCTION AND OBJECTIVES: Vesicoureteral reflux (VUR) has been one of the defining conditions unique to pediatric urology since its inception. The clinical implications of this disease process depend on intrinsic patient factors such as age, genetics, epigenetics, voiding habits, anatomic anomalies, and extrinsic factors such as the pathogenicity of infectious agents. Knowledge about its natural history, the implications of conservative and surgical management, and their associated outcomes have evolved dramatically over time...
April 24, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29770297/current-status-and-future-perspectives-of-the-pumpkin-trial
#12
REVIEW
Iki Adachi
Similar to the adult experience, the use of continuous-flow ventricular assist devices (VADs) has been increasing in the pediatric population. According to the PediMACS registry, continuous-flow VAD currently accounts for >60% of the durable device implantations in the U.S. Nonetheless, the continuous-flow VADs currently in use are designed for adults; this inevitably causes the patient-device size mismatch issue, especially when applied for small children. Pulsatile VADs, therefore, represent the only practical option for this group of patients despite the known risk profile of pulsatile VADs...
April 2018: Translational Pediatrics
https://www.readbyqxmd.com/read/29769453/comparison-of-the-long-term-efficacy-and-safety-of-gamma-knife-radiosurgery-for-arteriovenous-malformations-in-pediatric-and-adult-patients
#13
Hirotaka Hasegawa, Shunya Hanakita, Masahiro Shin, Mariko Kawashima, Wataru Takahashi, Osamu Ishikawa, Satoshi Koizumi, Hirofumi Nakatomi, Nobuhito Saito
It is debated whether the efficacy and long-term safety of gamma knife radiosurgery (GKRS) for arteriovenous malformations (AVMs) differs between adult and pediatric patients. We aimed to clarify the long-term outcomes of GKRS in pediatric patients and how they compare to those in adult patients. We collected data for 736 consecutive patients with AVMs treated with GKRS between 1990 and 2014 and divided the patients into pediatric (age < 20 years, n = 144) and adult (age ≥ 20 years, n = 592) cohorts. The mean follow-up period in the pediatric cohort was 130 months...
May 17, 2018: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/29766143/when-should-screening-of-pediatric-trauma-patients-for-adult-behaviors-start
#14
Adrian A Maung, Robert D Becher, Kevin M Schuster, Kimberly A Davis
Background: Care of patients with trauma is not only limited to the sustained physical injuries but also requires addressing social issues, such as substance abuse and interpersonal violence, which are responsible for trauma-related recidivism. This study investigates whether there are age-related variations in these problematic social behaviors to analyze whether there is an age cut-off at which point adolescents should be screened for adult social behaviors. Methods: Retrospective review of patients with trauma aged 12-21 admitted to an urban Level 1 adult and pediatric trauma center between February 2013 and April 2016...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29765943/juvenile-xanthogranuloma-in-a-pediatric-patient-with-langerhans-cell-histiocytosis
#15
Radha Ram, Marissa D Marolf, Patricia Chévez-Barrios, Honey H Herce
Purpose: To report a case of juvenile xanthogranuloma that simulated a chalazion and to discuss the association between juvenile xanthogranuloma and Langerhans cell histiocytosis. Method: Case report and review of literature. Results: A 13-year-old boy with a prior history of Langerhans cell histiocytosis was referred to our clinic for a possible chalazion. The patient had undergone treatment for Langerhans cell histiocytosis 10 years prior...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29765934/autoimmune-gastritis-in-the-pediatric-age-an-underestimated-condition-report-of-two-cases-and-review
#16
Chiara Saglietti, Amedeo Sciarra, Karim Abdelrahman, Vanessa Schneider, Arti Karpate, Andreas Nydegger, Christine Sempoux
Background: Diagnosis of pediatric autoimmune gastritis (AIG) in children is important due to poor outcome and risk of malignancy. This condition is often underestimated in the clinico-pathologic diagnostic work-up, leading to delayed time-to-diagnosis. To increase the awareness of this condition in the pediatric population, we present two cases encountered at our institution, discuss their clinical, biological, and histological presentations in relation with evidence from the literature, and propose an algorithm for diagnosis and follow-up of AIG in children...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29763444/cholelithiasis-and-choledocholithiasis-in-children-risk-factors-for-development
#17
Barbora Frybova, Jiri Drabek, Jindra Lochmannova, Ladislav Douda, Stepan Hlava, Daniela Zemkova, Vladimir Mixa, Martin Kyncl, Lubos Zeman, Michal Rygl, Radan Keil
PURPOSE: To compare anthropometric data (body mass index [BMI]) in patients without lithiasis to patients with symptomatic simple cholelithiasis or choledocholithiasis. METHODS: We retrospectively reviewed data from 147 patients undergoing laparoscopic cholecystectomy between 2001-2015. Complete growth data from 98 patients was compared with anthropometric data from the population of the Czech Republic and a control group (BMI of 100 consecutive patients without biliary stones in abdominal ultrasound who were admitted to a surgical department for suspected appendicitis)...
2018: PloS One
https://www.readbyqxmd.com/read/29762378/history-of-acquired-monosaccharide-intolerance-in-houston-texas
#18
William J Klish
It is appropriate that we begin the clinical part of this conference with a discussion of acquired monosaccharide intolerance. This disease is the most severe form of carbohydrate malabsorption and maldigestion that can afflict an infant. The following article describes the pathophysiology of the disease, as well as its treatment, much of which was based on studies done by the Section of Pediatric Gastroenterology and Nutrition at Baylor College of Medicine. Acquired monosaccharide intolerance has almost disappeared from the United States but remains a problem in the developing world where it is included as part of the diagnosis of environmental enteropathy...
June 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29762373/use-of-starch-and-modified-starches-in-infant-feeding-a-historical-perspective
#19
Frank R Greer
There is a long history of the use of starch in infant feeding. Proprietary infant foods (1867-1920) contained added starch from either cereal grains or malted carbohydrates. When evaporated milk became available in the 1920s, the use of proprietary foods fell out of favor. Evaporated milk formulas were a mixture of milk, water, and modified starch or milk sugar (lactose). By the late 1920s, however, corn syrup became the most common modified starch added to evaporated milk formulas as it was widely available, inexpensive, and readily accepted...
June 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29762362/on-king-saul-two-missing-mules-and-kingella-kingae-the-serendipitous-discovery-of-a-pediatric-pathogen
#20
Pablo Yagupsky, Ron Dagan
For the first two decades following Kingella kingae's initial characterization, this fastidious organism was considered an unusual cause of human infection until a study published in 1992 reported that inoculation of synovial fluid aspirates into blood culture vials improved the recovery of the bacterium. The authors of the original publication report herein the history of the discovery and review the progress made in the research of the organism.
May 14, 2018: Pediatric Infectious Disease Journal
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