Gianluca Conte, Sebastiano Antonio Pacino, Salvatore Urso, Doris Greiling, Pasquale Caponnetto, Eugenio Pedullà, Luigi Generali, Ugo Consolo, Vittorio Checchi, Stefan Gospodaru, Gheorghe Bordeniuc, Valeriu Fala, Jan Kowalski, Maciej Nowak, Renata Górska, Amaliya Amaliya, Iain Chapple, Michael Milward, Robert Maclure, Gianna Maria Nardi, Riccardo Polosa
BACKGROUND: Although the detrimental effects of conventional combustible cigarettes on oral health and dental esthetics are well known, there is limited information about the long-term impact of combustion-free nicotine alternatives (C-F NA) such as e-cigarettes or heated tobacco products. OBJECTIVE: This multicenter, prospective, 3-parallel-arm randomized controlled trial will investigate whether switching from combustible cigarettes to C-F NA will lead to measurable improvements in oral health parameters and dental esthetics over 18 months in adult smokers with limited gum disease...
February 23, 2024: JMIR Research Protocols