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https://www.readbyqxmd.com/read/29676856/age-related-changes-in-cortical-and-subcortical-structures-of-healthy-adult-brains-a-surface-based-morphometry-study
#1
Fenglian Zheng, Yulin Liu, Zilong Yuan, Xiaodong Gao, Yaoyao He, Xiaojing Liu, Dong Cui, Rui Qi, Tiao Chen, Jianfeng Qiu
BACKGROUND: Cerebral structures in both cortical and subcortical regions change with aging. More specific and comprehensive studies are needed to better elucidate these changes. PURPOSE: To investigate the relationships between age and cerebral structures regarding cortical and subcortical changes. STUDY TYPE: Cross-cohort research. POPULATION: 54 healthy adults (28 females) aged 21-71 years. FIELD STRENGTH/SEQUENCE: T1 -weighted imaging was performed at 1...
April 20, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29673966/automated-search-of-control-points-in-surface-based-morphometry
#2
Antonietta Canna, Andrea G Russo, Sara Ponticorvo, Renzo Manara, Alessandro Pepino, Mario Sansone, Francesco Di Salle, Fabrizio Esposito
Cortical surface-based morphometry is based on a semi-automated analysis of structural MRI images. In FreeSurfer, a widespread tool for surface-based analyses, a visual check of gray-white matter borders is followed by the manual placement of control points to drive the topological correction (editing) of segmented data. A novel algorithm combining radial sampling and machine learning is presented for the automated control point search (ACPS). Four data sets with 3 T MRI structural images were used for ACPS validation, including raw data acquired twice in 36 healthy subjects and both raw and FreeSurfer preprocessed data of 125 healthy subjects from public databases...
April 16, 2018: NeuroImage
https://www.readbyqxmd.com/read/29672876/regional-brain-volume-changes-in-alcohol-dependent-individuals-during-short-term-and-long-term-abstinence
#3
Xiaowei Zou, Timothy C Durazzo, Dieter J Meyerhoff
BACKGROUND: Widespread brain atrophy in alcohol-dependent individuals (ALC) has been consistently documented in pathological and magnetic resonance imaging (MRI) studies. Longitudinal MRI studies have shown that the regional brain volume losses in ALC are partially reversible during abstinence from alcohol. The goal of this study was to determine volume reductions in cortical and subcortical regions functionally important to substance use behavior and their changes during short-term (1 week to 1 month) and long-term abstinence (1 month to 7 months) from alcohol...
April 19, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29672584/fast-csf-mri-for-brain-segmentation-cross-validation-by-comparison-with-3d-t1-based-brain-segmentation-methods
#4
Lisa A van der Kleij, Jeroen de Bresser, Jeroen Hendrikse, Jeroen C W Siero, Esben T Petersen, Jill B De Vis
OBJECTIVE: In previous work we have developed a fast sequence that focusses on cerebrospinal fluid (CSF) based on the long T2 of CSF. By processing the data obtained with this CSF MRI sequence, brain parenchymal volume (BPV) and intracranial volume (ICV) can be automatically obtained. The aim of this study was to assess the precision of the BPV and ICV measurements of the CSF MRI sequence and to validate the CSF MRI sequence by comparison with 3D T1-based brain segmentation methods. MATERIALS AND METHODS: Ten healthy volunteers (2 females; median age 28 years) were scanned (3T MRI) twice with repositioning in between...
2018: PloS One
https://www.readbyqxmd.com/read/29671056/progressive-symptom-associated-prefrontal-volume-loss-occurs-in-first-episode-schizophrenia-but-not-in-affective-psychosis
#5
Toshiyuki Ohtani, Elisabetta Del Re, James J Levitt, Margaret Niznikiewicz, Jun Konishi, Takeshi Asami, Toshiro Kawashima, Tomohide Roppongi, Paul G Nestor, Martha E Shenton, Dean F Salisbury, Robert W McCarley
Although smaller gray matter volumes (GMV) in the prefrontal cortex (PFC) in schizophrenia and bipolar disorder have been reported cross-sectionally, there are, to our knowledge, no reports of longitudinal comparisons using manually drawn, gyrally based ROI, and their associations with symptoms. The object of this study was to determine whether first-episode schizophrenia (FESZ) and first-episode affective psychosis (FEAFF) patients show initial and progressive PFC GMV reduction in bilateral frontal pole, superior frontal gyrus (SFG), middle frontal gyrus (MFG), and inferior frontal gyrus (IFG) and examine their symptom associations...
April 18, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29665490/smaller-hippocampal-volume-in-current-but-not-in-past-depression-in-comparison-to-healthy-controls-minor-evidence-from-an-older-adults-sample
#6
Ismaïl Bensassi, Jorge Lopez-Castroman, Jerome J Maller, Chantal Meslin, Marilyn Wyart, Karen Ritchie, Philippe Courtet, Sylvaine Artero, Raffaella Calati
BACKGROUND: Structural neuroimaging studies revealed a consistent pattern of volumetric reductions in both hippocampus (HC) and anterior cingulate cortex (ACC) of individuals with major depressive episode(s) (MDE). This study investigated HC and ACC volume differences in currently depressed individuals (n = 150), individuals with a past lifetime MDE history (n = 79) and healthy controls (n = 287). METHODS: Non-demented individuals were recruited from a cohort of community-dwelling older adults (ESPRIT study)...
April 9, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29665283/accelerated-executive-functions-decline-and-gray-matter-structural-changes-in-middle-aged-type-1-diabetes-patients-with-proliferative-retinopathy
#7
Eelco van Duinkerken, Martijn D Steenwijk, Martin Klein, Frederik Barkhof, Daniel C Mograbi, Michaela Diamant, Frank J Snoek, Richard G Ijzerman
BACKGROUND: The aim of this study was to determine trajectories of cognitive and cortical changes over time in middle-aged patients with type 1 diabetes and proliferative retinopathy. METHODS: Twenty-five patients and 25 controls underwent neuropsychological assessment and neuroimaging twice in 3.56 ± 0.65 and 3.94 ± 0.91 years respectively (P = 0.098). Cognitive assessment included the domains of general cognitive ability, memory, information processing speed, executive functions, attention, motor and psychomotor speed...
April 17, 2018: Journal of Diabetes
https://www.readbyqxmd.com/read/29663507/grappa-reconstructed-wave-caipi-mp-rage-at-7-tesla
#8
Jolanda M Schwarz, Eberhard D Pracht, Daniel Brenner, Martin Reuter, Tony Stöcker
PURPOSE: The aim of this project was to develop a GRAPPA-based reconstruction for wave-CAIPI data. Wave-CAIPI fully exploits the 3D coil sensitivity variations by combining corkscrew k-space trajectories with CAIPIRINHA sampling. It reduces artifacts and limits reconstruction induced spatially varying noise enhancement. The GRAPPA-based wave-CAIPI method is robust and does not depend on the accuracy of coil sensitivity estimations. METHODS: We developed a GRAPPA-based, noniterative wave-CAIPI reconstruction algorithm utilizing multiple GRAPPA kernels...
April 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29660812/tremor-severity-in-parkinson-s-disease-and-cortical-changes-of-areas-controlling-movement-sequencing-a-preliminary-study
#9
Julián Benito-León, J Ignacio Serrano, Elan D Louis, Ales Holobar, Juan P Romero, P Povalej-Bržan, Félix Bermejo-Pareja, M Dolores Del Castillo, Ignacio J Posada, Eduardo Rocon
There remains much to learn about the changes in cortical anatomy that are associated with tremor severity in Parkinson's disease (PD). For this reason, we used a combination of structural neuroimaging to measure cortical thickness and neurophysiological studies to analyze whether PD tremor was associated with cortex integrity. Magnetic resonance imaging and neurophysiological assessment were performed in 13 nondemented PD patients (9 women, 69.2%) with a clearly tremor-dominant phenotype. Cortical reconstruction and volumetric segmentation were performed with the Freesurfer image analysis software...
April 16, 2018: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29659656/sexual-risk-taking-and-subcortical-brain-volume-in-adolescence
#10
Sarah W Feldstein Ewing, Karen A Hudson, Justin Caouette, Andrew R Mayer, Rachel E Thayer, Sephira G Ryman, Angela D Bryan
Background : The developmental period of adolescence marks the initiation of new socioemotional and physical behaviors, including sexual intercourse. However, little is known about neurodevelopmental influences on adolescent sexual decision-making. Purpose: We sought to determine how subcortical brain volume correlated with condom use, and whether those associations differed by gender and pubertal development. Methods: We used FreeSurfer to extract subcortical volume among N = 169 sexually experienced youth (mean age 16...
April 6, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29656266/cortical-and-subcortical-changes-in-patients-with-premenstrual-syndrome
#11
Peng Liu, Ying Wei, Yingying Fan, Hai Liao, Geliang Wang, Ru Li, Gaoxiong Duan, Demao Deng, Wei Qin
BACKGROUND: Premenstrual syndrome (PMS) is characterized by a series of emotional, physical and behavioral symptoms. Although PMS is related to dysfunctions of the central nervous system, the neuropathological mechanism of PMS still has not been clearly established. The aim of this study is to evaluate potential differences in both cortical thickness and subcortical volumes in PMS patients compared to healthy controls (HCs). METHODS: Twenty PMS patients and twenty HCs underwent a structural magnetic resonance imaging scan and clinical assessment...
April 7, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29625365/morphometric-mri-features-and-surgical-outcome-in-patients-with-epilepsy-related-to-hippocampal-sclerosis-and-low-intellectual-quotient
#12
Larissa Botelho Gaça, Maria Teresa Fernandes Castilho Garcia, Gabriel Barbosa Sandim, Idaiane Batista Assumption Leme, Maria Helena Silva Noffs, Henrique Carrete, Ricardo Silva Centeno, João Ricardo Sato, Elza Márcia Targas Yacubian
OBJECTIVE: The objectives of this study were to verify in a series of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) if those with low intellectual quotient (IQ) levels have more extended areas of atrophy compared with those with higher IQ levels and to analyze whether IQ could be a variable implicated on a surgical outcome. MATERIAL AND METHODS: Patients (n=106) with refractory MTLE-HS submitted to corticoamygdalohippocampectomy (CAH) (57 left mesial temporal lobe epilepsy (MTLE); 45 males) were enrolled...
April 3, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29618790/identification-of-individual-subjects-on-the-basis-of-their-brain-anatomical-features
#13
Seyed Abolfazl Valizadeh, Franziskus Liem, Susan Mérillat, Jürgen Hänggi, Lutz Jäncke
We examined whether it is possible to identify individual subjects on the basis of brain anatomical features. For this, we analyzed a dataset comprising 191 subjects who were scanned three times over a period of two years. Based on FreeSurfer routines, we generated three datasets covering 148 anatomical regions (cortical thickness, area, volume). These three datasets were also combined to a dataset containing all of these three measures. In addition, we used a dataset comprising 11 composite anatomical measures for which we used larger brain regions (11LBR)...
April 4, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29615675/predicting-individual-responses-to-the-electroconvulsive-therapy-with-hippocampal-subfield-volumes-in-major-depression-disorder
#14
Bo Cao, Qinghua Luo, Yixiao Fu, Lian Du, Tian Qiu, Xiangying Yang, Xiaolu Chen, Qibin Chen, Jair C Soares, Raymond Y Cho, Xiang Yang Zhang, Haitang Qiu
Electroconvulsive therapy (ECT) is one of the most effective treatments for major depression disorder (MDD). ECT can induce neurogenesis and synaptogenesis in hippocampus, which contains distinct subfields, e.g., the cornu ammonis (CA) subfields, a granule cell layer (GCL), a molecular layer (ML), and the subiculum. It is unclear which subfields are affected by ECT and whether we predict the future treatment response to ECT by using volumetric information of hippocampal subfields at baseline? In this study, 24 patients with severe MDD received the ECT and their structural brain images were acquired with magnetic resonance imaging before and after ECT...
April 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29614912/probing-culture-in-the-head-the-neural-correlates-of-relational-models
#15
Joseph Dien, Valerie Karuzis, Henk J Haarmann
Relational Models Theory or RMT proposes that there are four universal ways in which socio-economic relations can be organized. According to the RMT, each of its four relational models (Communal Sharing, Authority Ranking, Equality Matching, and Market Pricing) is associated with a distinct cognitive representation, with a cumulative pattern in which each relational model is a superset of the next lower model. This report for the first time uses a combination of cognitive and the social neuroscience to put this model to the test...
April 3, 2018: Social Neuroscience
https://www.readbyqxmd.com/read/29609076/negative-fateful-life-events-in-midlife-and-advanced-predicted-brain-aging
#16
Sean N Hatton, Carol E Franz, Jeremy A Elman, Matthew S Panizzon, Donald J Hagler, Christine Fennema-Notestine, Lisa T Eyler, Linda K McEvoy, Michael J Lyons, Anders M Dale, William S Kremen
Negative fateful life events (FLEs) such as interpersonal conflict, death in the family, financial hardship, and serious medical emergencies can act as allostatic stressors that accelerate biological aging. However, the relationship between FLEs and neuroanatomical aging is not well understood. We examined 359 men (mean age 62 years) participating in the Vietnam Era twin study of aging (VETSA) to determine whether negative midlife FLEs are associated with advanced brain aging after controlling for physical, psychological, and lifestyle factors...
March 8, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29605667/epitools-a-software-suite-for-presurgical-brain-mapping-in-epilepsy-intracerebral-eeg
#17
S Medina Villalon, R Paz, N Roehri, S Lagarde, F Pizzo, B Colombet, F Bartolomei, R Carron, C-G Bénar
BACKGROUND: In pharmacoresistant epilepsy, exploration with depth electrodes can be needed to precisely define the epileptogenic zone. Accurate location of these electrodes is thus essential for the interpretation of Stereotaxic EEG (SEEG) signals. As SEEG analysis increasingly relies on signal processing, it is crucial to make a link between these results and patient's anatomy. Our aims were thus to develop a suite of software tools, called "EpiTools", able to i) precisely and automatically localize the position of each SEEG contact and ii) display the results of signal analysis in each patient's anatomy...
March 29, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29593628/gray-matter-and-white-matter-abnormalities-in-temporal-lobe-epilepsy-patients-with-and-without-hippocampal-sclerosis
#18
Iman Beheshti, Daichi Sone, Farnaz Farokhian, Norihide Maikusa, Hiroshi Matsuda
The presentation and distribution of gray matter (GM) and white matter (WM) abnormalities in temporal lobe epilepsy (TLE) have been widely studied. Here, we investigated the GM and WM abnormalities in TLE patients with and without hippocampal sclerosis (HS) in five groups of participants: healthy controls (HCs) ( n  = 28), right TLE patients with HS ( n  = 26), right TLE patients without HS ( n  = 30), left TLE patients with HS ( n  = 25), and left TLE patients without HS ( n  = 27). We performed a flexible factorial statistical test in a whole-brain voxel-based morphometry analysis to identify significant GM and WM abnormalities and analysis of variance of hippocampal and amygdala regions among the five groups using the FreeSurfer procedure...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29572926/regional-brain-volumetry-and-brain-function-in-severely-brain-injured-patients
#19
Jitka Annen, Gianluca Frasso, Julia Sophia Crone, Lizette Heine, Carol Di Perri, Charlotte Martial, Helena Cassol, Athena Demertzi, Lionel Naccache, Steven Laureys
OBJECTIVE: The relationship between residual brain tissue in patients with disorders of consciousness (DOC) and the clinical condition is unclear. This observational study aimed to quantify gray (GM) and white matter (WM) atrophy in states of (altered) consciousness. METHODS: Structural T1-weighted magnetic resonance images were processed for 102 severely brain-injured and 52 healthy subjects. Regional brain volume was quantified for 158 (sub)cortical regions using Freesurfer...
March 24, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29567425/association-between-self-reported-impulsiveness-and-gray-matter-volume-in-healthy-adults-an-exploratory-mri-study
#20
J David Guerrero-Apolo, J Blas Navarro-Pastor, Antonio Bulbena-Vilarrasa, Julián Gabarre-Mir
This exploratory study investigated the association between self-reported impulsiveness and cortical gray matter volume (GMV) of the entire cortex in healthy adults. As a secondary objective and based on preliminary findings concerning the positive association between self-reported impulsiveness and the slant of the forehead degrees (SFD), we analyzed associations between SFD, GMV and impulsiveness. We obtained 48 structural magnetic resonances. The participants also completed BIS 11 and profile pictures were obtained...
March 19, 2018: Neuroscience Letters
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