Guhan Venkatakrishnan, Manikandan Kathirvel, Binoj Sivasankara Pillai Thankamony Amma, Abhijith K Muraleedharan, Johns S Mathew, Christi T Varghese, Krishnanunni Nair, Shweta Mallick, Madhu Srinivasan D, Unnikrishnan Gopalakrishnan, Dinesh Balakrishnan, Sudheer Othiyil Vayoth, Sudhindran Surendran
BACKGROUND: To compare the safety and efficacy of once-daily tacrolimus (ODT) versus twice-daily tacrolimus (BDT) in adult live donor liver transplantation (LDLT). METHODS: In this open-labelled randomized trial, 174 adult patients undergoing LDLT were randomized into ODT or BDT, combined with basiliximab induction and mycophenolate mofetil (steroid-free regimen). Tacrolimus was started at a total dose of 1 mg and the trough level was aimed at 3-7 ng/ml...
October 26, 2023: HPB: the Official Journal of the International Hepato Pancreato Biliary Association