Tristan Equey, Olivier Salamin, Federico Ponzetto, Raul Nicoli, Tiia Kuuranne, Jonas Saugy, Martial Saugy, Reid Aikin, Norbert Baume
CONTEXT: Detection of endogenous anabolic androgenic steroids (EAAS), like testosterone (T), as doping agents has been improved with the launch of the Steroidal Module of the Athlete Biological Passport (ABP) in urine samples. OBJECTIVE: To target doping practices with EAAS, particularly in individuals with low level of biomarkers excreted in urine, by including new target compounds measured in blood. DESIGN: T and T/Androstenedione (T/A4) distributions were obtained from 4 years of anti-doping data and applied as priors to analyze individual profiles from two T administration studies in female and male subjects...
February 16, 2023: Journal of Clinical Endocrinology and Metabolism