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Coffee derivatives

Anja Rahn, Chahan Yeretzian
This study examined the influence of consumer behavior on furan, 2-methylfuran, 3-methylfuran, 2,5-dimethylfuran and 2,3-dimethylfuran exposure in coffee. Coffees brewed using a filter, fully automatic, capsule machine or reconstituted instant coffee were found to have a significant different cup concentrations of furan derivatives. Coffee brewed with the fully automatic machine contained the highest furan and furan derivative concentrations (99.05 µg/L furan, 263.91 µg/L 2-methylfuran, 13.15 µg/L 3-methylfuran and 8...
January 30, 2019: Food Chemistry
Gilberto V de Melo Pereira, Dão P de Carvalho Neto, Antonio I Magalhães Júnior, Zulma S Vásquez, Adriane B P Medeiros, Luciana P S Vandenberghe, Carlos R Soccol
The aim of this review is to describe the volatile aroma compounds of green coffee beans and evaluate sources of variation in the formation and development of coffee aroma through postharvest processing. The findings of this survey showed that the volatile constituents of green coffee beans (e.g., alcohols, aldehydes, and alkanes) have no significant influence on the final coffee aroma composition, as only a few such compounds remain in the beans after roasting. On the other hand, microbial-derived, odor-active compounds produced during removal of the fruit mucilage layer, including esters, higher alcohols, aldehydes, and ketones, can be detected in the final coffee product...
January 30, 2019: Food Chemistry
Nivedita Singh, Ashwinee Kumar Shreshtha, M S Thakur, Sanjukta Patra
Medicinal plants have been the basis for discovery of various important marketed drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine, theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc. giving them popular recognition. These compounds are best known for their diverse pharmaceutical applications as cyclic nucleotide phosphodiesterase inhibition, antagonization of adenosine receptor, anti-inflammatory, anti-microbial, anti-oxidant and anti-tumor activities...
October 2018: Heliyon
Cees vanRijn
We have measured the dynamic surface tension of emanating coffee surfaces with a new method by studying the dynamics of an emanating liquid-air interface and compared obtained data with literature at small time scales between 1 and 100 ms. The emanating liquid-air interface is being described with an equation related to the well-known hydrostatic Young-Laplace equation for a pending liquid-air interface in which the only relevant forces are gravity g and surface tension γ. We explain that under specific constraints all mass parts of an emanating interface with density ρ will experience a same acceleration a(t)...
October 8, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
Ningjian Liang, David D Kitts
Understanding the potential effect of chlorogenic acid (CGA) isomers on the intestinal epithelium is important because coffee intake exposes consumers to the six major CGA isomers, 3-caffeoylquinic acid (3-CQA), 4-caffeoylquinic acid (4-CQA), 5-caffeoylquinic acid (5-CQA), 3,4-dicaffeoylquinic acid (3,4-diCQA), 3,5-dicaffeoylquinic acid (3,5-diCQA) and 4,5-dicaffeoylquinic acid (4,5-diCQA). The present study determined the relative effects of CGA isomers on the antioxidant status of inflamed Caco-2 intestinal cells by investigating the oxidative stress-responsive pathway and nuclear factor-erythroid-derived 2-like 2 (Nrf2) signaling...
September 27, 2018: Journal of Agricultural and Food Chemistry
Xiumin Chen, Kaiwen Mu, David D Kitts
Our previous study reported that different tea processing methods along with the age of coffee leaves affected antioxidant and anti-inflammatory bioactivities; however, identification of phytochemical components or associated mixtures that contribute to the anti-/pro-inflammatory activities was not determined. Herein, we report results of additional experiments designed to characterize the phytochemical composition of fractionated coffee leaf extract, derived from Japanese-style-green-tea-process-young (JGTP-Y) and black-tea-process-mature (BTP-M) leaves and related these data to anti-/pro-inflammatory activities...
January 15, 2019: Food Chemistry
Cheol Soo Yoon, Min Keun Kim, Yeon Sook Kim, Suk Keun Lee
RAW 264.7 cells and HUVECs were compared to evaluate the effects of dialyzed coffee extract (DCE) and artificial coffee (AC). Immunoprecipitation high performance liquid chromatography (IP-HPLC) showed DCE-2.5- (equivalent to 2.5 cups of coffee a day) and DCE-5-induced protein expression that was beneficial to human health, i.e., they led to significant increases in proliferation-, immunity-, cellular protection-, antioxidant signaling-, and osteogenesis-related proteins but decreases in inflammation-, NFkB signaling-, cellular apoptosis-, and oncogenic signaling-related proteins in RAW 264...
September 14, 2018: Scientific Reports
Julius Schuster, Ellen S Mitchell
In general, preparations of coffee, teas, and cocoa containing high levels of polyphenols, L-theanine and other bioactive compounds selectively enhance mood and cognition effects of caffeine. This review summarizes the bioactive components of commonly consumed natural caffeine sources (e.g. guayusa, mate and camellia teas, coffee and cocoa) and analyzes the psychopharmacology of constituent phytochemicals: methylxanthines, polyphenols, and L-theanine. Acute and chronic synergistic effects of these compounds on mood and cognition are compared and discussed...
September 10, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
Praetinee Pattamayutanon, Chi-Chung Peng, Chainarong Sinpoo, Panuwan Chantawannakul
This study was carried out to assess the impact of pollen feeding from common floral sources in Thailand (e.g., tea, coffee, and bitter bush) on royal jelly (RJ) properties (i.e., protein pattern, (E)-9-hydroxydec-2-enoic acid (9-HDA), and (E)-10-hydroxy-2-decenoic acid (10-HDA) contents and antibacterial activity). The protein patterns from three different pollen were different, while RJ samples derived from bee colonies fed by different pollen, exhibited similar protein patterns. RJ samples from bee colonies fed by pollen from bitter bush and coffee possessed the higher 10-HDA levels than RJ collected from bee colonies fed by tea pollen...
August 31, 2018: Journal of Economic Entomology
Chiara Magoni, Ilaria Bruni, Lorenzo Guzzetti, Mario Dell'Agli, Enrico Sangiovanni, Stefano Piazza, Maria Elena Regonesi, Mariateresa Maldini, Roberto Spezzano, Donatella Caruso, Massimo Labra
Coffee is the second traded food commodity in the world. Beyond roasted seeds, the most part of the original fruit -and in particular pulp- is discarded as waste, with severe environmental and economic consequences in many developing countries. Our research focused on developing an eco-friendly extraction protocol of phytocomplexes from coffee pulp and evaluating their bioactivity and beneficial effects to human health as food supplements. Antioxidant activity assays (Folin-Ciocalteu and DPPH assays) were adopted to select the most effective extraction technique and results show antioxidant activity of coffee pulp extracts...
October 2018: Food Research International
Alexandra Kasabova-Angelova, Diana Tzankova, Javor Mitkov, Maya Georgieva, Virginia Tzankova, Alexander Zlatkov, Magdalena Kondeva-Burdina
Parkinson's disease (PD) is a neurodegenerative and debilitating disease that affects 1% of elderly population. Patient's motor disability results in an extreme difficulty to deal with daily activities. Conventional treatment is limited to dopamine replacement therapy, which fails to delay disease's progression and is often associated with a number of adverse reactions. Recent progress in understanding the mechanisms involved in PD has revealed new molecular targets for therapeutic approaches. Among them, caffeine and xanthine derivatives are promising drug candidates, because of the possible symptomatic benefits in PD...
August 21, 2018: Current Medicinal Chemistry
Sisse Fagt, Jeppe Matthiessen, Camilla Thyregod, Karsten Kørup, Anja Biltoft-Jensen
Breakfast is considered by many to be the most important meal of the day. This study examined the intake of nutrients and foods at breakfast among Danes and the relation to the overall dietary quality. Data were derived from the Danish National Survey on Diet and Physical Activity 2011⁻2013, a cross-sectional national food consumption study. A total of 3680 participants aged 6⁻75 years were included in the analyses of breakfast consumption. The Nutrient Rich Food Index 9.3 method was used to examine the overall dietary quality of the diet...
August 14, 2018: Nutrients
Runa B Barnung, Therese H Nøst, Stine M Ulven, Guri Skeie, Karina S Olsen
Norwegians are the second highest consumers of coffee in the world. Lately, several studies have suggested that beneficial health effects are associated with coffee consumption. By analyzing whole-blood derived, microarray based mRNA gene expression data from 958 cancer-free women from the Norwegian Women and Cancer Post-Genome Cohort, we assessed the potential associations between coffee consumption and gene expression profiles and elucidated functional interpretation. Of the 958 women included, 132 were considered low coffee consumers (<1 cup of coffee/day), 422 moderate coffee consumers (1⁻3 cups of coffee/day), and 404 were high coffee consumers (>3 cups of coffee/day)...
August 9, 2018: Nutrients
Chyara Elisa Nofianti, Intan Novita Sari, Marlina, Novialdi, Jeanne Adiwinata Pawitan
Background: We have developed a simple lipoaspirate washing method using a coffee filter to eliminate liposuction noxious material before isolating adipose tissue derived mesenchymal stem cells (AT-MSCs), and used them in clinical trials. Before administration to patients, MSCs are usually suspended in physiologic saline. However, MSCs only survive for a limited time in physiologic saline. Therefore, alternative solution that can preserve MSC survival will be beneficial. Therefore, the purpose of this study was to compare the use of physiologic saline and Dulbecco's modified Eagle's Medium (DMEM) as temporary storage solution for our AT-MSCs...
2018: Stem Cell Investigation
Andrew M Freeman, Pamela B Morris, Karen Aspry, Neil F Gordon, Neal D Barnard, Caldwell B Esselstyn, Emilio Ros, Stephen Devries, James O'Keefe, Michael Miller, Dean Ornish, Kim A Williams, Travis Batts, Robert J Ostfeld, Sheldon Litwin, Monica Aggarwal, Andrea Werner, Kathleen Allen, Beth White, Penny Kris-Etherton
The potential cardiovascular (CV) benefits of many trending foods and dietary patterns are still incompletely understood, and scientific inquiry continues to evolve. In the meantime, however, a number of controversial dietary patterns, foods, and nutrients have received significant media attention and are mired by "hype." This second review addresses some of the more recent popular foods and dietary patterns that are recommended for CV health to provide clinicians with current information for patient discussions in the clinical setting...
July 31, 2018: Journal of the American College of Cardiology
Edyta Adamska-Patruno, Katarzyna Billing-Marczak, Marek Orlowski, Maria Gorska, Marcin Krotkiewski, Adam Kretowski
This study investigated the efficacy of a plant-derived dietary supplement with respect to decreasing postprandial glucose and insulin peaks after the intake of real-world meals. Two randomized, double-blind, placebo-controlled, cross-over experiments were conducted on healthy subjects who received a supplement containing extracts of white mulberry, white bean, and green coffee or one containing the three extracts with added fibre before consuming high-GI/GL (glycaemic index/glycaemic load) meals. In study one, 32 subjects received an investigational product/placebo before a standardized meal at two visits...
July 25, 2018: Nutrients
Junko Kawahara, Yoshitaka Imaizumi, Keisuke Kuroda, Yasunobu Aoki, Noriyuki Suzuki
Acrylamide is a probable human carcinogen and known human neurotoxin. This study estimated hypothetical long-term dietary exposure to acrylamide of the Japanese people using probabilistic and deterministic approaches by combining the concentration of acrylamide in foods with the amount and frequency of food consumption in the population. Data included acrylamide concentrations in more than 2400 individual food samples from a national survey and the literature from 2004 to 2013. Food consumption amounts were derived from the data of 24,293 Japanese citizens aged 1 year and older in the 2012 National Health and Nutrition Survey...
September 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Megan Jarman, Nonsikelelo Mathe, Fatemeh Ramazani, Mohammadreza Pakseresht, Paula J Robson, Steven T Johnson, Rhonda C Bell
Few studies have explored pre-pregnancy diet and its relationship with pregnancy outcomes. The objectives of this study were to: (1) derive pre-pregnancy dietary patterns for women enrolled in a prospective cohort in the province of Alberta, Canada; (2) describe associations between dietary patterns and socio-demographic characteristics; and (3) describe associations between dietary patterns and pregnancy complications. Upon enrolment into the Alberta Pregnancy Outcomes and Nutrition (APrON) study (median age of gestation, 17 weeks), women ( n = 1545) completed a validated 142-item food frequency questionnaire recording food and beverages consumed "in the 12 months prior to pregnancy"...
July 17, 2018: Nutrients
Joseph A Rothwell, Francisco Madrid-Gambin, Mar Garcia-Aloy, Cristina Andres-Lacueva, Caomhan Logue, Alison M Gallagher, Carina Mack, Sabine E Kulling, Qian Gao, Giulia Praticò, Lars O Dragsted, Augustin Scalbert
Non-alcoholic beverages are important sources of nutrients and bioactive compounds that may influence human health and increase or decrease the risk of chronic diseases. A wide variety of beverage constituents are absorbed in the gut, found in the systemic circulation and excreted in urine. They may be used as compliance markers in intervention studies or as biomarkers of intake to improve measurements of beverage consumption in cohort studies and reveal new associations with disease outcomes that may have been overlooked when using dietary questionnaires...
2018: Genes & Nutrition
Mirko De Rosso, Silvia Colomban, Riccardo Flamini, Luciano Navarini
Chlorogenic acids are relevant coffee quality markers, taste, and aroma precursors as well as important bioactive compounds. A number of mono-acyl, di-acyl, and tri-acyl quinic acid isomers were found in green coffee beans, being mono-caffeoyl, mono-feruloyl, mono-p-coumaroyl, and di-caffeoylquinic acid isomers considered as quantitatively major compounds. Roasting process increases the chemical complexity of coffee by inducing the formation of a number of lactones (quinides), shikimates, and other chlorogenic acids derivatives...
July 4, 2018: Journal of Mass Spectrometry: JMS
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