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Prevention Of Delayed Haemolysis Reactions In Transfusion Reactions

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https://www.readbyqxmd.com/read/8751307/post-transfusion-hyperhaemolysis-in-a-patient-with-sickle-cell-disease-use-of-steroids-and-intravenous-immunoglobulin-to-prevent-further-red-cell-destruction
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J O Cullis, N Win, J M Dudley, T Kaye
Delayed haemolytic transfusion reactions (DHTRs) are seen more frequently in patients with sickle cell disease (SCD) than in other groups of patients, and are characterised by a positive direct antiglobulin test and the appearance of previously undetected red blood cell (RBC) alloantibodies in the patient's serum. Recently a syndrome of post-transfusion hyperhaemolysis has been described in children with SCD, characterised by destruction of both autologous and transfused RBCs with negative serological findings: continuation of RBC transfusion exacerbated haemolysis further...
1995: Vox Sanguinis
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