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Restorative proctocolectomy

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https://www.readbyqxmd.com/read/30540661/abnormal-pouchogram-predicts-pouch-failure-even-in-asymptomatic-patients
#1
Philip H Sossenheimer, Laura R Glick, Abraham Dachman, Kinga B Skowron, Michele Rubin, Konstantin Umanskiy, Radhika Smith, Lisa Cannon, Roger D Hurst, Russell D Cohen, Neil H Hyman, David T Rubin
BACKGROUND: Anastomotic complications after restorative total proctocolectomy with IPAA for ulcerative colitis alter functional outcomes and quality of life and may lead to pouch failure. Routine contrast enema of the pouch assesses anastomotic integrity before ileostomy reversal, but its clinical use is challenged. OBJECTIVE: The purpose of this research was to assess the relationship among preoperative clinical characteristics, abnormal pouchography, and long-term pouch complications...
November 28, 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/30527503/clinical-outcomes-after-ileal-pouch-anal-anastomosis-in-pediatric-patients
#2
Christina C Huang, Frederick J Rescorla, Matthew P Landman
BACKGROUND: Ileal pouch-anal anastomosis (IPAA) is the standard surgical reconstruction for patients with familial adenomatous polyposis (FAP) and ulcerative colitis (UC) who undergo total proctocolectomy (TPC). Although patients receive the same reconstruction, their postoperative complications can differ. We hypothesize that indication for TPC and other preoperative clinical factors are associated with differences in postoperative outcomes following IPAA. METHODS: A retrospective cohort of pediatric patients who underwent proctocolectomy with IPAA from 1996 to 2016 was identified...
February 2019: Journal of Surgical Research
https://www.readbyqxmd.com/read/30470567/bilateral-pyoderma-gangrenosum-associated-with-ulcerative-colitis-and-restorative-proctocolectomy
#3
Mónica Llorente Barrio, Santiago García López, Yolanda Gilaberte Calzada, Rosario María Monzón Báez, Diego Casas Deza, Luis Javier Lamuela Calvo
No abstract text is available yet for this article.
November 20, 2018: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/30460346/long-term-outcomes-following-restorative-proctocolectomy-ileal-pouch-anal-anastomosis-in-pediatric-ulcerative-colitis-patients-multicenter-national-study-in-japan
#4
Hiroki Ikeuchi, Motoi Uchino, Akira Sugita, Kitaro Futami, Kouhei Fukushima, Keisuke Hata, Kazutaka Koganei, Masato Kusunoki, Keiichi Uchida, Riichiro Nezu, Hideaki Kimura, Kenichi Takahashi, Michio Itabashi, Hitoshi Kameyama, Daijiro Higashi, Fumikazu Koyama, Takeshi Ueda, Tsunekazu Mizushima, Yasuo Suzuki
Background: Few studies have investigated surgical outcomes following a colectomy in pediatric patients with ulcerative colitis (UC). Purpose: This study aimed to determine long-term outcomes in a large cohort of pediatric patients who underwent proctocolectomy with ileal pouch-anal anastomosis (IPAA) for UC. Methods: Pediatric patients (<17 years old) who underwent surgery at 12 different hospitals in Japan between May 1979 and March 2015 were included in this study...
November 2018: Annals of gastroenterological surgery
https://www.readbyqxmd.com/read/30454506/j-pouch-prolapse-as-a-late-complication-of-restorative-proctocolectomy
#5
Remil Simon, Keith Hollister, J Daniel Stanley, Shauna Lorenzo-Rivero
No abstract text is available yet for this article.
September 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/30430012/diagnosis-and-management-of-floppy-pouch-complex
#6
REVIEW
Freeha Khan, Tracy L Hull, Bo Shen
Restorative proctocolectomy with ileal pouch-anal anastomosis has become the surgical treatment of choice for patients with refractory ulcerative colitis, colitis-associated dysplasia or familial adenomatous polyposis. There are various pouch disorders and associated complications. Floppy pouch complex is defined as the presence of pouch prolapse, afferent limb syndrome, enterocele, redundant loop and folding pouch on pouchoscopy, gastrografin pouchogram or defecography. Common clinical presentation includes dyschezia, bloating, abdominal pain, straining or the sense of incomplete evacuation...
November 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/30416152/-recalcitrant-pouchitis-treated-by-budesonide-foam-a-case-report
#7
Naoyuki Tominaga, Sanae Tsuruta, Takahiro Yukimoto, Shimpei Shirai, Shinichi Ogata
This report presents the case of a 54-year-old man who had undergone restorative proctocolectomy with ileal pouch-anal anastomosis 15 years previously because of acute severe ulcerative colitis. After the operation, he experienced recalcitrant pouchitis and recurrent ulcer bleeding. There was a marked improvement in his symptoms following the administration of twice-daily budesonide 2mg foam injection for two months. Budesonide foam is suggested as a new therapy for pouchitis.
2018: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/30346218/long-term-functional-outcome-after-restorative-proctocolectomy-a-cross-sectional-study
#8
Ilona Helavirta, Marja Hyöty, Heini Huhtala, Pekka Collin, Petri Aitola
OBJECTIVE: Restorative proctocolectomy is the procedure of choice in the surgical treatment of ulcerative colitis. Functional outcome is the key result of surgery. The aim of this study was to evaluate the long term-functional outcome after the procedure. MATERIAL AND METHODS: The study comprised 282 ulcerative colitis patients over 18 years of age who underwent restorative proctocolectomy between1985 and 2009. The median follow-up time was 13 years (range 4-28)...
October 22, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/30327916/characterization-of-megapouch-in-patients-with-restorative-proctocolectomy
#9
Preeti Shashi, Bo Shen
BACKGROUND: Megapouch is a rare functional complication of restorative proctocolectomy with ileal pouch-anal anastomosis characterized by pouch ± small bowel dilatation with no evidence of obstruction on endoscopy and imaging. Little is known about clinical characteristics and outcomes of this entity. METHODS: We included all patients diagnosed with megapouch at our institution, identified from a pouch database. Data on baseline characteristics, management, and outcomes were documented and analyzed from electronic medical records...
October 16, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30324385/are-radiologic-pouchogram-and-pouchoscopy-useful-before-ileostomy-closure-in-asymptomatic-patients-operated-for-ulcerative-colitis
#10
Georgios Exarchos, Linda Metaxa, Antonios Gklavas, Vassilis Koutoulidis, Ioannis Papaconstantinou
OBJECTIVES: Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the "gold standard" procedure for patients with ulcerative colitis (UC) requiring surgical intervention. A de-functioning ileostomy is usually performed, as a step for the IPAA procedure. The aim of this study is to present the methodology and results of the routine double assessment of IPAA integrity in asymptomatic patients prior to the ileostomy reversal and evaluate its necessity. METHODS: This is a retrospective study of 61 UC patients, who underwent IPAA construction, in 2010-2016...
October 15, 2018: European Radiology
https://www.readbyqxmd.com/read/30312385/risk-factors-for-small-bowel-obstruction-after-laparoscopic-ileal-pouch-anal-anastomosis-for-inflammatory-bowel-disease-a-multivariate-analysis-in-4-expert-centres-in-europe
#11
D Mege, F Colombo, M E Stellingwerf, A Germain, L Maggiori, D Foschi, C J Buskens, A de Buck van Overstraeten, G Sampietro, A D'Hoore, W Bemelman, Y Panis
Background and Aims: Although laparoscopic a1pproach is associated with the reduction of adhesions, no data are available about risk factors for small bowel obstruction (SBO) after laparoscopic ileal pouch-anal anastomosis (IPAA). The objective is to identify risk factors for SBO after laparoscopic IPAA for inflammatory bowel disease (IBD). Methods: All consecutive patients undergoing laparoscopic IPAA for IBD in 4 European expert centres were included and divided into Groups A (SBO during follow up) and B (no SBO)...
October 11, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/30270685/long-term-outcomes-of-initial-infliximab-therapy-for-inflammatory-pouch-pathology-a-multi-centre-retrospective-study
#12
Jonathan P Segal, Lawrence Penez, Soad Mohsen Elkady, Guy H T Worley, Simon D McLaughlin, Benjamin H Mullish, Mohammed N Quraishi, Nik S Ding, Tamara Glyn, Kesavan Kandiah, Mark A Samaan, Peter M Irving, Omar D Faiz, Susan K Clark, Ailsa L Hart
BACKGROUND: Restorative proctocolectomy with ileal pouch-anal anastomosis is considered the procedure of choice in patients with ulcerative colitis refractory to medical therapy. Subsequent inflammation of the pouch is a common complication and in some cases, pouchitis fails to respond to antibiotics, the mainstay of treatment. In such cases, corticosteroids, immunomodulatory or biologic treatments are options. However, our understanding of the efficacy of anti-tumour necrosis factor medications in both chronic pouchitis and Crohn's-like inflammation is based on studies that include relatively small numbers of patients...
September 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/30269715/j-pouch-prolapse-as-a-late-complication-of-restorative-proctocolectomy
#13
Remil Simon, Keith Hollister, J Daniel Stanley, Shauna Lorenzo-Rivero
No abstract text is available yet for this article.
September 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/30268206/j-pouch-prolapse-as-a-late-complication-of-restorative-proctocolectomy
#14
Remil Simon, Keith Hollister, J Daniel Stanley, Shauna Lorenzo-Rivero
No abstract text is available yet for this article.
September 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/30259096/judging-the-j-pouch-a-pictorial-review
#15
REVIEW
Shannon P Sheedy, David J Bartlett, Amy L Lightner, Steven W Trenkner, David H Bruining, Jeff L Fidler, Wendaline M VanBuren, Christine O Menias, Joshua D Reber, Joel G Fletcher
Restorative total proctocolectomy with ileal pouch-anal anastomosis is the surgery of choice for patients with medically refractory ulcerative colitis, ulcerative colitis with high-grade dysplasia or multi-focal low-grade dysplasia, and for patients with familial adenomatous polyposis. The natural history of the surgery is favorable, and patients generally experience improved quality of life and acceptable long-term functional outcome. However, some patients experience significant long-term morbidity from early and/or late pouch-related complications...
September 27, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/30241963/current-surgical-practice-in-pediatric-ulcerative-colitis-a-systematic-review
#16
REVIEW
Sharman P Tan Tanny, Minjung Yoo, John M Hutson, Jacob C Langer, Sebastian K King
BACKGROUND: Surgical management of adult ulcerative colitis (UC) is well-studied, but not readily applicable to children. Restorative proctocolectomy with ileal pouch-anal anastomosis (RPC-IPAA), performed as one-, two-, or three-stage procedure, is preferred in pediatric patients with adequate anal sphincter function. PURPOSE: METHODS: Systematic review of Cochrane Register of Controlled Trials, PubMed, and EMBASE databases was conducted (January 1987-December 2016), in accordance with PRISMA...
September 7, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30218632/acceptability-effectiveness-and-safety-of-a-renew-%C3%A2-anal-insert-in-patients-who-have-undergone-restorative-proctocolectomy-with-ileal-pouch-anal-anastomosis
#17
Jonathan P Segal, Cosimo Alex Leo, Jonathan D Hodgkinson, Emanuel Cavazzoni, Elissa Bradshaw, Phillip F C Lung, Rajpandian Ilangovan, Carolynne J Vaizey, Omar D Faiz, Ailsa L Hart, Susan K Clark
INTRODUCTION: Restorative proctocolectomy has gained acceptance in the surgical management of medically refractive ulcerative colitis and cancer prevention in familial adenomatous polyposis. Incontinence following restorative proctocolectomy occurs in up to 25% of patients overnight. The Renew® insert is an inert single use device which acts as an anal plug. The aim of this study was to assess the acceptability, effectiveness and safety of the Renew® insert in patients who have undergone restorative proctocolectomy...
September 15, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/30151202/vedolizumab-in-the-treatment-of-crohn-s-disease-of-the-pouch
#18
Freeha Khan, Xian-Hua Gao, Amandeep Singh, Jessica R Philpott, Bo Shen
Background: Our recent study showed the efficacy and safety of vedolizumab in the treatment of chronic antibiotic-refractory pouchitis. However, there are no published studies on its efficacy and safety in Crohn's disease (CD) of the pouch. The aim of this study was to assess the efficacy and safety of vedolizumab in those patients. Methods: This case series included all eligible patients with CD of the pouch from our prospectively maintained, IRB-approved Pouchitis Registry from 2015 to 2017...
August 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/30124882/a-comprehensive-approach-to-pouch-disorders
#19
Kevin P Quinn, Amy L Lightner, William A Faubion, Laura E Raffals
Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical procedure of choice for patients with medically refractory ulcerative colitis (UC) or indeterminate colitis, UC with colonic dysplasia or neoplasia, and familial adenomatous polyposis. In general, patients experience good function outcomes and quality of life with an IPAA. Although pouchitis is the most well-recognized and frequent complication after IPAA, a number of additional inflammatory, postsurgical, structural, neoplastic, and functional complications may occur, resulting in pouch dysfunction...
August 16, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/30112936/indications-and-outcomes-of-home-parenteral-nutrition-in-patients-with-an-ileoanal-pouch
#20
S M Oke, J Segal, S K Clark, A L Hart, S M Gabe
INTRODUCTION: Restorative proctocolectomy is a surgical treatment for patients with medically refractory ulcerative colitis and some cases of familial adenomatous polyposis. Intestinal failure, defined as an inability to maintain adequate hydration and micronutrient balances when on a conventionally accepted normal diet, is a rare complication of restorative proctocolectomy. We describe our experience of patients with restorative proctocolectomy who have developed intestinal failure requiring parenteral support...
August 16, 2018: Annals of the Royal College of Surgeons of England
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