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Early neglect and later trauma

Julia Woodhall-Melnik, James R Dunn, Stephen Svenson, Caroline Patterson, Flora I Matheson
Previous studies that have explored the association between childhood trauma and homelessness indicate that traumatic events can lead to survivor distrust of interpersonal relationships and institutions, prolonged homelessness and poor health and social outcomes. The majority of this literature relies on quantitative data and fails to investigate the personal experiences of childhood trauma that are found to impact housing status later in life. Semi-structured, qualitative interviews were conducted with 25 men living in an urban area in Ontario who had spent more than 30 consecutive nights in an emergency shelter over the course of their housing histories...
April 4, 2018: Child Abuse & Neglect
Yuliya I Kuras, Naomi Assaf, Myriam V Thoma, Danielle Gianferante, Luke Hanlin, Xuejie Chen, Alexander Fiksdal, Nicolas Rohleder
Childhood adversity, such as neglect, or physical, emotional, or sexual abuse, is prevalent in the U.S. and worldwide, and connected to an elevated incidence of disease in adulthood. A pathway in this relationship might be altered hypothalamic-pituitary-adrenal (HPA) axis functioning, as a result of differential hippocampal development in early life. A blunted diurnal cortisol slope is a precursor for many disorders. While studies have focused on HPA reactivity in relation to childhood adversity, there has been markedly less research on basal HPA functioning in those with low-to-moderate adversity...
2017: Frontiers in Human Neuroscience
Jingbo Gong, Raymond C K Chan
The aim of the current study was to examine whether early maladaptive schemas (EMSs) mediate the association between different kinds of childhood maltreatment and later psychopathology and the effect of different kinds of childhood maltreatment on psychological distress in later life. A total of 1102 college students from two local universities participated in the study; their average age was 20.46 ± 1.13 years. The participants completed the Childhood Trauma Questionnaire (CTQ), the Early Maladaptive Schemas Scale (EMSs), the Zung Self-Rating Depression Scale (SDS), and the Zung Self-Rating Anxiety Scale (SAS)...
January 2018: Psychiatry Research
E Asselmann, J Stender, H J Grabe, J König, C O Schmidt, A O Hamm, C A Pané-Farré
BACKGROUND: Although research suggests that (a) childhood adversities and more recent stressful life events/conditions are risk factors for panic pathology and that (b) early life stress increases vulnerability to later psychopathology, it remains unclear whether childhood adversities amplify the association between more recent stressful life events/conditions and panic pathology. METHODS: Data were derived from a general population sample (Study of Health in Pomerania, SHIP)...
January 1, 2018: Journal of Affective Disorders
Magdalena Romanowicz, Alastair J McKean, Jennifer Vande Voort
BACKGROUND: Long-term effects of neglect in early life are still widely unknown. Diversity of outcomes can be explained by differences in genetic risk, epigenetics, prenatal factors, exposure to stress and/or substances, and parent-child interactions. Very common sub-threshold presentations of children with history of early trauma are challenging not only to diagnose but also in treatment. CASE PRESENTATION: A Caucasian 4-year-old, adopted at 8 months, male patient with early history of neglect presented to pediatrician with symptoms of behavioral dyscontrol, emotional dysregulation, anxiety, hyperactivity and inattention, obsessions with food, and attachment issues...
September 11, 2017: BMC Psychiatry
Christa Krüger, Lizelle Fletcher
We investigate the types of childhood maltreatment and abuser-abused relational ties that best predict a dissociative disorder (DD). Psychiatric inpatients (n = 116; mean age = 35; F:M = 1.28:1) completed measures of dissociation and trauma. Abuse type and abuser-abused relational ties were recorded in the Traumatic Experiences Questionnaire. Multidisciplinary team clinical diagnosis or administration of the SCID-D-R to high dissociators confirmed DD diagnoses. Logit models described the relationships between abuser-abused relational tie and the diagnostic grouping of patients, DD present (n = 16) or DD absent (n = 100)...
May 2017: Journal of Trauma & Dissociation
Aïda Cancel, Magali Comte, Claire Boutet, Fabien C Schneider, Pierre-François Rousseau, Sarah Boukezzi, Aurélia Gay, Torrance Sigaud, Catherine Massoubre, Fabrice Berna, Xavier Y Zendjidjian, Jean-Michel Azorin, Olivier Blin, Eric Fakra
Childhood trauma strongly impacts emotional responses in schizophrenia. We have explored an association between early trauma and the amygdala functional connectivity using generalized psychophysiological interaction during an emotional task. Twenty-one schizophrenia patients and twenty-five controls were included. In schizophrenia patients, higher levels of sexual abuse and physical neglect during childhood were associated with decreased connectivity between the amygdala and the posterior cingulate/precuneus region...
June 2017: Schizophrenia Research
Kelly Quinn, Lauren Boone, Joy D Scheidell, Pedro Mateu-Gelabert, Susan P McGorray, Nisha Beharie, Linda B Cottler, Maria R Khan
BACKGROUND: We examined associations between childhood trauma and adulthood prescription pain reliever misuse (PPRM) and injection drug use (IDU) in a nationally-representative U.S. sample to further understanding of factors associated with these epidemics. METHODS: National Longitudinal Study of Adolescent to Adult Health data (N=12,288) yielded nine childhood traumas: neglect; emotional, physical, sexual abuse; parental incarceration and binge drinking; witnessed, threatened with, and experienced violence...
December 1, 2016: Drug and Alcohol Dependence
Beth S Brodsky
Adverse childhood experiences are associated with higher risk for suicide and suicidal behavior later in life. There are known associations between childhood trauma, particularly sexual abuse, and higher rates of suicide, non-lethal suicide attempts, and non-suicidal self-injurious behaviors in adolescence and adulthood. Emotional abuse/neglect, disrupted parental attachment, and cumulative effect of multiple forms of maltreatment, also increase risk. Yet, the causal relationship remains unclear. The diathesis-stress model provides a framework for understanding how early life adverse experiences contribute to suicide vulnerability...
September 2016: Current Psychiatry Reports
Sebastian Wolff, Julia Holl, Malte Stopsack, Elisabeth A Arens, Anja Höcker, Katharina A Staben, Philipp Hiller, Michael Klein, Ingo Schäfer, Sven Barnow
BACKGROUND/AIMS: Maltreatment in childhood and adolescence is a risk factor for substance use disorders (SUDs) in adulthood. This association has rarely been investigated in the light of emotion dysregulation. To fill this gap, this study examines emotion dysregulation and SUDs among adults with a history of early maltreatment. METHODS: Comparison of emotion dysregulation in adults with a history of early abuse and neglect who developed either an SUD (n = 105) or no mental disorder (n = 54)...
2016: European Addiction Research
Darcey H Merritt, Sacha Klein
Young children under 6 years old are over-represented in the U.S. child welfare system (CWS). Due to their exposure to early deprivation and trauma, they are also highly vulnerable to developmental problems, including language delays. High quality early care and education (ECE) programs (e.g. preschool, Head Start) can improve children's development and so policymakers have begun calling for increased enrollment of CWS-supervised children in these programs. However, it is not a given that ECE will benefit all children who experience maltreatment...
January 2015: Child Abuse & Neglect
Stefan Kempke, Patrick Luyten, Sarah De Coninck, Boudewijn Van Houdenhove, Linda C Mayes, Stephan Claes
BACKGROUND: There is a paucity of studies that have investigated the assumption that early childhood trauma is associated with hypothalamic-pituitary-adrenal (HPA) axis dysfunction in Chronic Fatigue Syndrome (CFS). The current study is the first to simultaneously investigate relationships among early childhood trauma, cortisol activity, and cortisol stress reactivity to psychosocial stress in a sample of well-screened CFS patients. We also examined whether self-critical perfectionism (SCP) plays a mediating role in the potential relationship between early trauma and neurobiological stress responses...
February 2015: Psychoneuroendocrinology
Jerrold S Meyer, Amanda F Hamel
Stressful life events have been linked to the onset of severe psychopathology and endocrine dysfunction in many patients. Moreover, vulnerability to the later development of such disorders can be increased by stress or adversity during development (e.g., childhood neglect, abuse, or trauma). This review discusses the methodological features and results of various models of stress in nonhuman primates in the context of their potential relevance for human psychopathology and endocrine dysfunction, particularly mood disorders and dysregulation of the hypothalamic-pituitary-adrenocortical (HPA) system...
2014: ILAR Journal
Andrea Schulz, Mathias Becker, Sandra Van der Auwera, Sven Barnow, Katja Appel, Jessie Mahler, Carsten Oliver Schmidt, Ulrich John, Harald J Freyberger, Hans J Grabe
OBJECTIVE: Data suggests that traumatic experiences at early age contribute to the onset of major depressive disorder (MDD) in later life. This study aims at investigating the influence of dispositional resilience on this relationship. METHODS: Two thousand and forty-six subjects aged 29-89 (SD=13.9) from a community based sample who were free of MDD during the last 12 months prior to data collection were diagnosed for Lifetime diagnosis of MDD by the Munich-Composite International Diagnostic Interview (M-CIDI) according to DSM-IV criteria...
August 2014: Journal of Psychosomatic Research
Kathryn L Humphreys, Charles H Zeanah
Current frameworks for understanding the link between early adverse childhood experiences and later negative life outcomes, including psychopathology, focus on the mediating negative impact on brain and biological systems in the developing child resulting broadly from stress and trauma. Although this approach is useful, we argue that the framework could be functionally extended by distinguishing the effects of two different types of abnormal input, both deviations from the expectable environment in early childhood...
January 2015: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
Peter A Bos, Estrella R Montoya, David Terburg, Jack van Honk
Animal studies show that exposure to parental neglect alters stress regulation and can lead to neural hyposensitivity or hypersensitivity in response to cortisol, most pronounced in the hippocampus. Cortisol, the end product of the hypothalamic-pituitary-adrenal (HPA) axis, has also been related to parenting more directly, for example, in both sexes, cortisol levels increase when listening to infants crying, possibly to activate and facilitate effective care behavior. Severe trauma is known to negatively affect the HPA-axis in humans; however, it is unknown whether normal variation in parental care in the healthy population can alter sensitivity of the hippocampus to cortisol...
October 2014: Human Brain Mapping
Karen A Matthews, Yue-Fang Chang, Rebecca C Thurston, Joyce T Bromberger
OBJECTIVE: Elevated inflammation biomarkers are associated with incident cardiovascular disease. Several studies suggest that childhood abuse may be associated with inflammation later in life. This study examined whether childhood abuse predicted elevated levels of C-reactive protein (CRP) and whether the association was due to body size. METHODS: Participants were 326 (104 Black, 222 White) women from the Pittsburgh site of the Study of Women's Health Across the Nation (SWAN)...
February 2014: Brain, Behavior, and Immunity
Regina M Sullivan
Decades of research have shown that childhood experiences interact with our genetics to change the structure and function of the brain. Within the range of normal experiences, this system enables the brain to be modified during development to adapt to various environments and cultures. Experiences with and attachment to the caregiver appear particularly important, and recent research suggests this may be due, in part, to the attachment circuitry within the brain. Children have brain circuitry to ensure attachment to their caregivers...
August 2012: Hastings Law Journal
Charlotte Jaite, Ernst Pfeiffer, Ulrike Lehmkuhl, Harriet Salbach-Andrae
OBJECTIVES: Some studies suggest that both early sexual and early physical abuse are non-specific risk factors for the later development of eating disorders (EDs). However, only little is known about the role of emotional abuse in EDs. METHODS: The sample included 77 inpatients with Anorexia nervosa (AN-R: n = 50; AN-BP: n = 27), 26 psychiatric control participants and 44 healthy control participants, all of whom were females. The diagnosis of AN and the diagnosis of psychiatric control participants were confirmed by structured interviews (SIAB-EX, Fichter & Quadflieg, 1999; CIDI-DIA-X,Wittchen & Pfister, 1997)...
March 2013: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
M D Bartholomeusz, R Callister, D M Hodgson
There is considerable evidence that early life stress (ELS) can have a lasting impact upon adult physiology. Various childhood (and even prenatal) stressors such as parental separation, neglect, and trauma, can leave an enduring impact upon immune, autonomic and endocrine systems. These changes are increasingly understood to represent vulnerabilities to developing later life medical (and psychological) morbidity. In this article it is hypothesized that these enduring physiological changes may also serve as markers to detect the presence of ELS or rather it's impact upon the individual...
February 2013: Medical Hypotheses
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