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https://www.readbyqxmd.com/read/29132768/pr%C3%A3-vention-et-prise-en-charge-de-l%C3%A2-infection-herp%C3%A3-tique-au-cours-de-la-grossesse-et-de-l%C3%A2-accouchement%C3%A2-recommandations-pour-la-pratique-clinique-%C3%A2-%C3%A2-texte-des-recommandations-texte-court
#1
M-V Sénat, O Anselem, O Picone, L Renesme, N Sananès, C Vauloup-Fellous, Y Sellier, J-P Laplace, L Sentilhes
OBJECTIVE: Identify measures to diagnose, prevent and treat genital herpes infection during pregnancy and childbirth and neonatal infection. METHODS: Bibliographic search from Medline, Cochrane Library databases and research of international clinical practice guidelines. RESULTS: Genital herpes lesion is most often due to HSV2 (LE2). The risk of HSV seroconversion during pregnancy is 1 to 5% (LE2). Genital herpes ulceration during pregnancy in a woman with history of genital herpes corresponds with a recurrence...
November 10, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29115946/seropositivity-to-herpes-simplex-virus-type-2-but-not-type-1-is-associated-with-cervical-cancer-nhanes-1999-2014
#2
Sen Li, Xi Wen
BACKGROUND: Herpes simplex virus types 1 and 2 (HSV1 and HSV2) are infectious agents, and their association with cancer occurrence in human is a controversial topic for decades. We addressed this subject using all available continuous National Health and Nutrition Examination Survey (NHANES) cross-sectional data from 1999 to 2014. METHODS: Eight data cycles (1999-2000, 2001-2002, 2003-2004, 2005-2006, 2007-2008, 2009-2010, 2011-2012, and 2013-2014) were employed, and a sample of 8184 female participants was used in this study according to the availability of cancer history and HSV serostatus...
November 7, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29113531/detection-of-cytomegalovirus-herpes-virus-simplex-and-parvovirus-b19-in-spontaneous-abortion-placentas
#3
Gabriela Mafra de Oliveira, Marcelo Antônio Pascoal-Xavier, Daniel R Moreira, Vitor Souza Guimarães, Regina Amélia Lopes Pessoa de Aguiar, Débora Marques de Miranda, Roberta Maia de Castro Romanelli
OBJECTIVE: This study aims to investigate the presence of Cytomegalovirus (CMV), herpes virus simplex (HSV), and parvovirus B19 (PVB19) in the placental tissue of patients who underwent abortions without an otherwise-defined aetiology. STUDY DESIGN: This cross-sectional study was conducted in a high-risk obstetric maternity facility at a University Hospital in Belo Horizonte, Brazil, from January 2013 to December 2015. We included placenta samples obtained from spontaneous abortions of unknown aetiology...
November 7, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29045430/the-association-between-herpes-virus-infections-and-functional-somatic-symptoms-in-a-general-population-of-adolescents-the-trails-study
#4
Iris Jonker, Robert Schoevers, Hans Klein, Judith Rosmalen
BACKGROUND: FSS have been suggested to follow activation of the immune system, triggered by herpes virus infections. The aim of this study was to find out whether herpes virus infections were associated with the experience of FSS in adolescents, and whether this association was mediated by hsCRP, as a general marker of immune activation. METHODS: This study was performed in TRAILS, a large prospective population cohort of 2230 adolescents (mean age: 16.1 years, SD = ...
2017: PloS One
https://www.readbyqxmd.com/read/29036805/determining-the-igm-and-igg-antibodies-titer-against-hsv1-hsv2-and-cmv-in-the-serum-of-schizophrenia-patients
#5
Masome Mohagheghi, Mohammad Yousef Alikhani, Mohammad Taheri, Mohammad Mahdi Eftekharian
Schizophrenia is a destructive clinical syndrome with diverse mental pathologies. Different mechanisms and factors have a role in this disease. A possible mechanism is that teratogenic viruses cause brain changes and results in the disease appearance. The schizophrenia patients were diagnosed by psychologists and with the consent of patients, five CC of venous blood was drawn. Than Serum samples were isolated and immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies against herpes simplex virus-1 (HSV-1), herpes simplex virus-2 (HSV-2) and cytomegalovirus (CMV) were quantified by ELISA sandwich kit...
September 8, 2017: Human Antibodies
https://www.readbyqxmd.com/read/28979799/network-analysis-of-the-hominin-origin-of-herpes-simplex-virus-2-from-fossil-data
#6
Simon J Underdown, Krishna Kumar, Charlotte Houldcroft
Herpes simplex virus 2 (HSV2) is a human herpesvirus found worldwide that causes genital lesions and more rarely causes encephalitis. This pathogen is most common in Africa, and particularly in central and east Africa, an area of particular significance for the evolution of modern humans. Unlike HSV1, HSV2 has not simply co-speciated with humans from their last common ancestor with primates. HSV2 jumped the species barrier between 1.4 and 3 MYA, most likely through intermediate but unknown hominin species. In this article, we use probability-based network analysis to determine the most probable transmission path between intermediate hosts of HSV2, from the ancestors of chimpanzees to the ancestors of modern humans, using paleo-environmental data on the distribution of African tropical rainforest over the last 3 million years and data on the age and distribution of fossil species of hominin present in Africa between 1...
July 2017: Virus Evolution
https://www.readbyqxmd.com/read/28962197/differential-expression-of-mrna-and-mirna-in-guinea-pigs-following-infection-with-hsv2v
#7
Lin Kuang, Yihui Deng, Xiaodan Liu, Zhixiang Zou, Lan Mi
MicroRNAs (miRNAs) are 22-nucleotide single-stranded RNAs which regulate gene expression by targeting 3' untranslated regions. Previous studies have suggested that miRNAs may be used as markers for investigating the molecular regulation of gene expression. In the present study, miRNA and mRNA expression profiles were investigated using a massively parallel next generation sequencing technique to compare herpes simplex virus (HSV)2-infected (n=3) and healthy (n=3) epithelial tissues from guinea pigs. Total RNA was isolated and RNA sequencing was performed using a HiSeq 2000 sequencing system...
September 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28954265/differential-detection-of-enterovirus-and-herpes-simplex-virus-in-cerebrospinal-fluid-by-real-time-rt-pcr
#8
Brenda Sarquiz-Martínez, César R González-Bonilla, Clara Esperanza Santacruz-Tinoco, José E Muñoz-Medina, Héctor D Pardavé-Alejandre, Elizabeth Barbosa-Cabrera, José Ernesto Ramírez-González, José Alberto Díaz-Quiñonez
BACKGROUND: Enterovirus (EV) and herpes simplex virus 1 and 2 (HSV1 and HSV2) are the main etiologic agents of central nervous system infections. Early laboratory confirmation of these infections is performed by viral culture of the cerebrospinal fluid (CSF), or the detection of specific antibodies in serum (e.g., HSV). The sensitivity of viral culture ranges from 65 to 75%, with a recovery time varying from 3 to 10 days. Serological tests are faster and easy to carry out, but they exhibit cross-reactivity between HSV1 and HSV2...
September 28, 2017: Intervirology
https://www.readbyqxmd.com/read/28929964/-investigation-of-bacterial-and-viral-etiology-in-community-acquired-central-nervous-system-infections-with-molecular-methods
#9
Hasip Kahraman, Alper Tünger, Şebnem Şenol, Hörü Gazi, Meltem Avcı, Bahar Örmen, Nesrin Türker, Sabri Atalay, Şükran Köse, Sercan Ulusoy, Meltem Işıkgöz Taşbakan, Oğuz Reşat Sipahi, Tansu Yamazhan, Zeynep Gülay, Sema Alp Çavuş, Hüsnü Pullukçu
In this multicenter prospective cohort study, it was aimed to evaluate the bacterial and viral etiology in community-acquired central nervous system infections by standart bacteriological culture and multiplex polymerase chain reaction (PCR) methods. Patients hospitalized with central nervous system infections between April 2012 and February 2014 were enrolled in the study. Demographic and clinical information of the patients were collected prospectively. Cerebrospinal fluid (CSF) samples of the patients were examined by standart bacteriological culture methods, bacterial multiplex PCR (Seeplex meningitis-B ACE Detection (Streptococcus pneumoniae, Neisseria meningitidis, Haemophilus influenzae, Listeria monocytogenes, Group B streptococci) and viral multiplex PCR (Seeplex meningitis-V1 ACE Detection kits herpes simplex virus-1 (HSV1), herpes simplex virus-2 (HSV2), varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein Barr virus (EBV) and human herpes virus 6 (HHV6)) (Seeplex meningitis-V2 ACE Detection kit (enteroviruses))...
July 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28746988/the-association-between-clinical-outcome-and-cd8-lymphocytic-infiltration-in-advanced-stages-of-colorectal-cancer-differs-by-latent-virus-infection-in-the-tumour-tissue
#10
Britta Kleist, Marius Bagdonas, Prakash Oommen, Irina Schoenhardt, Janina Levermann, Micaela Poetsch
AIMS: In near future, an immunoscore based on the quantification of lymphocytic populations can be expected as fundamental supplement of colorectal cancer (CRC) classification. This study explored, whether latent viral infection has an influence on prognostic relevant host immunity in CRC. METHODS AND RESULTS: CD8+ lymphocytic infiltration in three tumour compartments of 121 CRC was compared with clinical data and occurrence of latent infection with HSV1, HSV2, CMV, EBV, HPV16, and HPV18 in the tumour tissue, which was determined by PCR...
July 26, 2017: Histopathology
https://www.readbyqxmd.com/read/28688377/no-role-of-herpes-simplex-virus-type-2-hsv-2-infection-on-hiv-progression-in-na%C3%A3-ve-hiv-patients
#11
Minoo Mohraz, Arezoo Aghakhani, Saeedeh Moayedi-Nia, Mohammad Banifazl, Alireza Janbakhsh, Setareh Mamishi, Afsaneh Karami, Anahita Bavand, Pegah Mirzapour, Amitis Ramezani
Background: Herpes simplex virus type 2 (HSV-2) is a common infection in human immunodeficiency virus (HIV) patients and may accelerate HIV progression by rising HIV viral load and decreasing CD4 count. However, the available data regarding the influence of HSV-2 seropositivity on HIV progression in HIV individuals are inconclusive. Therefore, we aimed to determine HSV-2 seroprevalence in naïve HIV patients and normal controls and also investigate the relation of HIV viral load and CD4 count with HSV-2 seropositivity...
July 9, 2017: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/28683784/decreasing-seroprevalence-of-herpes-simplex-virus-type-1-and-type-2-in-germany-leaves-many-people-susceptible-to-genital-infection-time-to-raise-awareness-and-enhance-control
#12
Gerit Korr, Michael Thamm, Irina Czogiel, Christina Poethko-Mueller, Viviane Bremer, Klaus Jansen
BACKGROUND: Herpes simplex infections (HSV1/2) are characterized by recurrent symptoms, a risk of neonatal herpes, and the facilitation of HIV transmission. In Germany, HSV1/2 infections are not notifiable and data are scarce. A previous study found higher HSV1/2 seroprevalences in women in East Germany than in women in West Germany. We assessed changes in the HSV1/2 seroprevalences over time and investigated determinants associated with HSV1/2 seropositivity to guide prevention and control...
July 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28566076/-evaluation-of-viral-etiology-in-central-nervous-system-infections-from-a-university-hospital-point-of-view-in-izmir-based-on-seven-years-data
#13
Ayşın Zeytinoğlu, Selda Erensoy, Rüçhan Sertöz, İmre Altuğlu, Candan Çiçek, Münevver Kayın, Hadiye Şirin, Şafak Taner
The serious diseases of the central nervous system (CNS); encephalitis and meningitis, have high mortality and morbidity rate especially not diagnosed and treated in time. Nucleic acid testing (NAT) is the tool of choice for viral diagnosis in CNS infections. In this study, viral etiological agents found in cerebrospinal fluid (CSF) samples sent to our university hospital virology laboratory for laboratory diagnosis of CNS infections were retrospectively evaluated and results were compared with other reports from our country...
April 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28491117/herpes-virus-seroepidemiology-in-the-adult-swedish-population
#14
Jan Olsson, Eloise Kok, Rolf Adolfsson, Hugo Lövheim, Fredrik Elgh
BACKGROUND: Herpes viruses establish a life-long latency and can cause symptoms during both first-time infection and later reactivation. The aim of the present study was to describe the seroepidemiology of Herpes simplex type 1 (HSV1), Herpes simplex type 2 (HSV2), Cytomegalovirus (CMV), Varicella Zoster virus (VZV) and Human herpes virus type 6 (HHV6) in an adult Swedish population (35-95 years of age). METHODS: Presence of antibodies against the respective viruses in serum from individuals in the Betula study was determined with an enzyme-linked immunosorbent assay (ELISA)...
2017: Immunity & Ageing: I & A
https://www.readbyqxmd.com/read/28468588/a-herpes-simplex-virus-type-2-encoded-microrna-promotes-tumor-cell-metastasis-by-targeting-suppressor-of-cytokine-signaling-2-in-lung-cancer
#15
Xudong Wang, Shupeng Liu, Zhenhua Zhou, Hongli Yan, Jianru Xiao
Certain viruses use microRNAs to regulate the expression of their own genes, host genes, or both. A number of microRNAs expressed by herpes simplex virus type 2 have been confirmed by previous studies. However, whether these microRNAs play a role in the metastasis of lung cancers and how these viral microRNAs precisely regulated the tumor biological process in lung cancer bone metastasis remain obscure. We recently identified the high expression of an acutely and latently expressed viral microRNA, Hsv2-miR-H9-5p, encoded by herpes simplex virus type 2 latency-associated transcript through microarray and quantitative polymerase chain reaction analyses which compared the expression of microRNAs in bone metastasis from lung cancer with primary lung cancers...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28282487/establishment-of-multiplex-solid-phase-strip-pcr-test-for-detection-of-24-ocular-infectious-disease-pathogens
#16
Satoko Nakano, Sunao Sugita, Yasuhiro Tomaru, Ayumi Hono, Takako Nakamuro, Toshiaki Kubota, Hiroshi Takase, Manabu Mochizuki, Masayo Takahashi, Norio Shimizu
Purpose: To establish and evaluate a new multiplex solid-phase strip polymerase chain reaction (strip PCR) for concurrent detection of common ocular infectious disease pathogens. Methods: A new multiplex strip PCR was established to detect 24 common ocular infectious disease pathogens: herpes simplex virus (HSV) 1, HSV2, varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), human herpes virus (HHV) 6, HHV7, HHV8, human T-cell lymphotropic virus (HTLV)-1, adenovirus, Mycobacterium tuberculosis, Treponema pallidum, Propionibacterium acnes (P...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28242091/-dermatoses-and-herpes-superinfection-a-retrospective-study-of-34%C3%A2-cases
#17
V Seta, F Fichel, J-F Méritet, S Bouam, N Franck, M-F Avril, N Dupin
BACKGROUND: Although varicelliform Kaposi eruption is a well-known complication of dermatoses, it has not been widely investigated. AIM: To investigate features of dermatoses and herpes superinfection in patients hospitalized in a dermatology department. PATIENTS AND METHODS: We performed a single-centre, retrospective study between 2008 and 2014 that included cases of Kaposi varicelliform eruptions defined by positive PCR of an unconventional site of herpetic recurrence in a setting of active dermatitis...
March 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28178213/neurotrophic-factors-ngf-gdnf-and-ntn-selectively-modulate-hsv1-and-hsv2-lytic-infection-and-reactivation-in-primary-adult-sensory-and-autonomic-neurons
#18
Andy A Yanez, Telvin Harrell, Heather J Sriranganathan, Angela M Ives, Andrea S Bertke
Herpes simplex viruses (HSV1 and HSV2) establish latency in peripheral ganglia after ocular or genital infection, and can reactivate to produce different patterns and frequencies of recurrent disease. Previous studies showed that nerve growth factor (NGF) maintains HSV1 latency in embryonic sympathetic and sensory neurons. However, adult sensory neurons are no longer dependent on NGF for survival, some populations cease expression of NGF receptors postnatally, and the viruses preferentially establish latency in different populations of sensory neurons responsive to other neurotrophic factors (NTFs)...
February 7, 2017: Pathogens
https://www.readbyqxmd.com/read/28150409/bizarre-cell-dysplasia-of-the-cervix
#19
Ondrej Ondič, Radoslav Ferko, Jana Kašpírková, Marián Švajdler, Boris Rýchly, Peter Talarčík, Jiří Bouda, Michal Michal
AIM: The aim of this study was the characterization of a new subtype of high-grade cervical squamous intraepithelial lesion (HSIL) with enlarged cells containing bizarre nuclei: so-called bizarre cell dysplasia (BCD). METHODS: A total of 29 cervical cone biopsy samples of this type of dysplasia were studied. Multi-target polymerase chain reaction and in situ hybridization human papillomavirus (HPV) detection was performed in all cases. BCD was defined as a subtype of HSIL characterized by the presence of large dysplastic cells with abnormal, large pleomorphic nuclei or multinucleation causing nucleomegaly...
February 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28043100/erratum-increased-expression-of-herpes-virus-encoded-hsv1-mir-h18-and-hsv2-mir-h9-5p-in-cancer-containing-prostate-tissue-compared-to-that-in-benign-prostate-hyperplasia-tissue
#20
Seok Joong Yun, Pildu Jeong, Ho Won Kang, Helen Ki Shinn, Ye-Hwan Kim, Chunri Yan, Young-Ki Choi, Dongho Kim, Dong Hee Ryu, Yun-Sok Ha, Tae-Hwan Kim, Tae Gyun Kwon, Jung Min Kim, Sang Heon Suh, Seon-Kyu Kim, Seon-Young Kim, Sang Tae Kim, Won Tae Kim, Ok-Jun Lee, Sung-Kwon Moon, Nam-Hyung Kim, Isaac Yi Kim, Jayoung Kim, Hee-Jae Cha, Yung-Hyun Choi, Eun-Jong Cha, Wun-Jae Kim
[This corrects the article on p. 122 in vol. 20, PMID: 27377944.].
December 2016: International Neurourology Journal
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