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https://www.readbyqxmd.com/read/29928771/polyhydroxybutyrate-production-by-an-extremely-halotolerant-halomonas-elongata-strain-isolated-from-the-hypersaline-meromictic-f%C3%A4-r%C3%A4-fund-lake-transylvanian-basin-romania
#1
Adorján Cristea, Andreea Baricz, Nicolae Leopold, Călin Gabriel Floare, Gheorghe Borodi, Irina Kacso, Septimiu Tripon, Paul Adrian Bulzu, Ștefan Andrei Adrian, Oana Cadar, Erika Andrea Levei, Horia Leonard Banciu
AIM: This study aimed at unprecedented physical and chemical evaluation of the 'green plastics' polyhydroxyalkanoates (PHAs), in an extremely halotolerant Halomonas elongata strain 2FF under high salt concentration. METHODS AND RESULTS: The investigated bacterial strain was isolated from the surface water of the hypersaline Fără Fund Lake. The 16S rRNA gene sequence phylogeny and phenotypic analysis indicated that the isolate belonged to Halomonas elongata. PHA inclusions were observed by Sudan Black B, Nile Red staining and by transmission electron microscopy (TEM) during growth at high salinity (10%, w/v, NaCl) on 1% (w/v) D-glucose...
June 21, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29040928/calorimetric-and-spectroscopic-studies-of-the-interaction-between-zidovudine-and-human-serum-albumin
#2
Adrian Pîrnău, Mihaela Mic, Silvia Neamţu, Călin G Floare, Mircea Bogdan
A quantitative analysis of the interaction between zidovudine (AZT) and human serum albumin (HSA) was achieved using Isothermal titration calorimetry (ITC) in combination with fluorescence and1 H NMR spectroscopy. ITC directly measure the heat during a biomolecular binding event and gave us thermodynamic parameters and the characteristic association constant. By fluorescence quenching, the binding parameters of AZT-HSA interaction was determined and location to binding site I of HSA was confirmed. Via T1 NMR selective relaxation time measurements the drug-protein binding extent was evaluated as dissociation constants Kd and the involvement of azido moiety of zidovudine in molecular complex formation was put in evidence...
February 15, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/27840767/the-influence-of-the-variety-vineyard-and-vintage-on-the-romanian-white-wines-quality
#3
Anamaria Hosu, Veronica Floare-Avram, Dana Alina Magdas, Ioana Feher, Mihai Inceu, Claudia Cimpoiu
The wine is one of the most consumed drinks over the world, being subjected to falsification or adulteration regarding the variety, vintage, and geographical region. In this study, the influence of different characteristics of wines (type, production year, and origin) on the total phenolic content, total flavonoids content, antioxidant activity, total sugars content, pH, and (18)O/(16)O isotopic ratio was investigated. The differentiation of selected wines on the basis of tested parameters was investigated using chemometric techniques, such as analysis of variance, cluster analysis, and principal component analysis...
2016: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/25826271/radiological-protection-evaluation-of-the-bucharest-tandetron-3%C3%A2-mv-accelerator
#4
I O Mitu, G Floare, D G Ghiţă, D V Moşu, Gh Căta-Danil
Low energy heavy charged particle accelerators are generators of ionizing radiation, due to the ion beam interactions into the machine components, targets and surrounding materials. Nowadays there are available computational tools allowing realistic estimates of radiation doses and residual activity of the activated components. These evaluations are further used to design the radiological safety system required by licensing and operation of the equipment.This paper presents results of measurements and numerical simulations of the radiation doses and residual activity, at the recently commissioned Bucharest 3 MV Cockcroft-Walton type Tandetron accelerator presently used mainly for Ion Beam Analysis (IBA) research...
June 2015: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/25653521/clinical-and-pathological-implications-of-mirna-in-bladder-cancer
#5
REVIEW
Cornelia Braicu, Roxana Cojocneanu-Petric, Sergiu Chira, Anamaria Truta, Alexandru Floares, Bogdan Petrut, Patriciu Achimas-Cadariu, Ioana Berindan-Neagoe
MicroRNAs (miRNAs) are small, noncoding RNA species with a length of 20-22 nucleotides that are recognized as essential regulators of relevant molecular mechanisms, including carcinogenesis. Current investigations show that miRNAs are detectable not only in different tissue types but also in a wide range of biological fluids, either free or trapped in circulating microvesicles. miRNAs were proven to be involved in cell communication, both in pathological and physiological processes. Evaluation of the global expression patterns of miRNAs provides key opportunities with important practical applications, taking into account that they modulate essential biological processes such as epithelial to mesenchymal transition, which is a mechanism relevant in bladder cancer...
2015: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/25591256/-the-place-of-osteosynthesis-with-screwed-up-metallic-plates-in-the-treatment-of-the-shaft-fractures-of-the-forearm-bones
#6
G Floareş, N Georgescu, A Ciureanu
The modern findings regarding the biomechanics of the forearm call for an as perfect as possible reduction of the fractures at this level. That is why, especially in adults, the surgical treatment is gaining more and more ground. In this context the osteosynthesis with screwed up metallic plates, preferably with compression, any time the local situation allows, it, represents the method of choice. In the 333 cases operated upon during 1971-1980 it has offered us full satisfaction. The taping with Küntscher nail was indicated--especially in the past--only in some fractures of ulna, mainly in the oblique ones, in which the rod is blocking more easily the rotary motions...
January 1982: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/24286093/solid-parotid-tumors-an-individual-and-integrative-analysis-of-various-ultrasonographic-criteria-a-prospective-and-observational-study
#7
COMPARATIVE STUDY
Alexandru Florin Badea, Simion Bran, Attila Tamas-Szora, Alexandru Floareş, Radu Badea, Grigore Baciut
OBJECTIVES: The purpose of the study is to identify and validate ultrasound criteria for parotid tumors evaluation, as well as to elaborate a multimodal, multi-criteria and integrative ultrasound approach for allowing tumor discrimination in a non-invasive manner. MATERIAL AND METHOD: Twenty patients with solid parotid tumors (12 benign, 8 malignant) were examined by ultrasound: real-time "grey scale" ultrasound, Doppler ultrasound, elastography, harmonic ultrasound imaging with i...
December 2013: Medical Ultrasonography
https://www.readbyqxmd.com/read/20658719/oxaliplatin-in-patients-with-metastatic-colorectal-cancer-efficacy-and-pharmacokinetics-parameters
#8
C Burz, I Berindan-Neagoe, O Balacescu, N Todor, D Pelau, C Floares, G Kacso, C Tanaselia, M Ursu, L Vlase, S E Leucuta, V Cristea, A Irimie
PURPOSE: The aim of this study was to investigate the efficiency of the FOLFOX-4 regimen and to evaluate the pharmacokinetics of oxaliplatin in untreated patients with metastatic colorectal cancer. METHODS: 43 patients were enrolled in the study. Patients received oxaliplatin 85 mg/m(2) as 2-h i.v. infusion, on day 1, and bolus 5-fluorouracil (5FU) 400 mg/m(2) plus leucovorin (LV) 200 mg/m(2) followed by 5FU 600 mg/m(2) as 22-h infusion on day 1 and 2, every 2 weeks...
April 2010: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/18495406/binding-interaction-of-indomethacin-with-human-serum-albumin
#9
M Bogdan, A Pirnau, C Floare, Carmen Bugeac
The interaction between indomethacin and human serum albumin (HSA) was investigated by fluorescence quenching technique and UV-vis absorption spectroscopy. The results of fluorescence titration revealed that indomethacin, strongly quench the intrinsic fluorescence of HSA by static quenching and nonradiative energy transfer. The binding site number n and the apparent binding constant K(A), were calculated using linear and nonlinear fit to the experimental data. The distance r between donor (HSA) and acceptor (indomethacin) was obtained according to fluorescence resonance energy transfer (FRET)...
August 5, 2008: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/18243654/a-reverse-engineering-algorithm-for-neural-networks-applied-to-the-subthalamopallidal-network-of-basal-ganglia
#10
Alexandru George Floares
Modeling neural networks with ordinary differential equations systems is a sensible approach, but also very difficult. This paper describes a new algorithm based on linear genetic programming which can be used to reverse engineer neural networks. The RODES algorithm automatically discovers the structure of the network, including neural connections, their signs and strengths, estimates its parameters, and can even be used to identify the biophysical mechanisms involved. The algorithm is tested on simulated time series data, generated using a realistic model of the subthalamopallidal network of basal ganglia...
March 2008: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/16296534/-reconstruction-of-the-anterior-cruciate-ligament-of-the-knee-by-lindemann-s-procedure
#11
G Floareş, N Georgescu
No abstract text is available yet for this article.
October 1976: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/16296499/-indications-of-the-treatment-with-enders-elastic-nail-in-fractures-of-the-femur
#12
G Floareş, N Georgescu, L Popescu, C Săvescu
No abstract text is available yet for this article.
July 1978: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/15352791/freezing-on-heating-of-liquid-solutions
#13
M Plazanet, C Floare, M R Johnson, R Schweins, H P Trommsdorff
We report a reversible liquid-solid transition upon heating of a simple solution composed of a-cyclodextrine (alpha CD), water, and 4-methylpyridine. These solutions are homogeneous and transparent at ambient temperature and solidify when heated to temperatures between 45 degrees and 75 degrees. Quasielastic and elastic neutron scattering show that molecular motions are slowed down in the solid and that crystalline order is established. The solution "freezes on heating." This process is fully reversible, on cooling the solid melts...
September 15, 2004: Journal of Chemical Physics
https://www.readbyqxmd.com/read/14298686/-considerations-on-a-case-of-fibrous-dysplasia-of-the-jaffe-lichtenstein-type
#14
G FLOARES
No abstract text is available yet for this article.
April 1964: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/14298658/-albright-s-syndrome
#15
G FLOARES, C DOLINESCU, MIHAILESCU
No abstract text is available yet for this article.
January 1964: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/14222112/-endocrine-disorders-in-polyostotic-fibrous-dysplasia
#16
G FLOARES
No abstract text is available yet for this article.
1964: Studii şi Cercetari de Endocrinologie
https://www.readbyqxmd.com/read/12092153/-history-of-orthopedics-and-traumatology
#17
G Floareş
No abstract text is available yet for this article.
January 2001: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/10756757/-a-rare-form-of-osteopoikilosis
#18
REVIEW
G Floareş, E Zbranca, A Creţu, O Cernomaz
The authors report a typical case of osteopoikilosis striata Voorhoeve in a 51-years-old female. In connection with case they make some consideration concerning the diagnostic of this very infrequent sclerotic bone dysplasia.
January 1997: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/9524664/-the-treatment-of-giant-cell-tumors-of-the-lower-extremity-of-the-radius-by-resection-reconstruction
#19
REVIEW
G Floareş
The location of the mega-cell tumours in the inferior extremity of radius is relatively frequent and it represents 10 percent from all mega-cell tumours. The aggressive tumours and the relapsed one must be cut-away. In 3 of the cases which were operated, after a large cutting of the tumour, the author used for reconstruction a grafting from the fibula-bone without vascularisation. The fixing of the focus metallic plates is highly superior to other osteosynthesis. After 3 years, now relapse was remarked. The functional results can be considered good-enough, even some of patients can not perform hard-working...
January 1995: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/9455476/-the-therapeutic-orientation-in-vertical-fractures-of-the-patella
#20
G Floareş, A Creţu, S Hobincă
Starting from the rareness of vertical fractures of the patella, in connection with a clinical case, the authors present this entity and the therapeutical problems in correction with this type of fracture. Interfragmentary diastasis is more than 3 mm, so the authors choose for treatment the osteosynthesis with a spongious screw placed horizontally, perpendicular on the fracture, keeping the integrity of the prepatellar fibrous planes. The authors appreciate that orthopedic treatment is reserved to the incomplete fractures or fractures without displacement...
July 1996: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
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