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Mehmet Volkan Harput, Ayda Parnian Fard, Ugur Türe
Intramedullary tumors of the spinal cord are rare and account for 2% to 8.5% of all central nervous system tumors. In adults, ependymomas are the most common intramedullary tumors. The primary choice of treatment should be radical surgical removal, as this is curative for most tumors. Adequate tumor exposure is crucial and mostly achieved through standard laminectomy followed by midline myelotomy. However, extensive removal of posterior spinal elements may lead to worsening kyphotic deformities. After obtaining patient consent, this 3-dimensional video publication was prepared to present microneurosurgical removal of a C3-C6 cervical intramedullary tumor using right-sided hemilaminoplasty...
December 12, 2018: Operative Neurosurgery (Hagerstown, Md.)
S S Malchau, A A Henningsen, J Forman, A Loft, A Nyboe Andersen, A Pinborg
STUDY QUESTION: Is the number of aspirated oocytes in the first ART cycle associated with the cumulative live birthrates (CLBR) in subsequent cycles? SUMMARY ANSWER: The number of aspirated oocytes in the first cycle was associated with CLBR in subsequent cycles. Previous treatment response predicts outcome in future cycles. WHAT IS KNOWN ALREADY: Previous reports have shown a positive association between the number of retrieved oocytes and live birthrate per fresh treatment cycle...
December 12, 2018: Human Reproduction
Sheldon P Hersh, Joshua N Hersh
Red ear syndrome (RES) is an unusual, often unrecognized condition that has rarely been reported in the otolaryngology literature despite the presence of symptoms and associated disorders of relevance to the otolaryngologist. When present, RES may have diagnostic value when uncertainties arise in cases of sinus headache and referred otalgia. Despite the appearance of a distinctive red ear, as well as symptoms and associated disorders relating to otolaryngology, discussion of RES is generally limited to neurology-based publications...
December 2018: Ear, Nose, & Throat Journal
Lely Solari
We are going through a moment in which acts of disregard to the ethics in the public function are being disclosed at all levels. It is important to know the codes of ethics and good practices of each of the functions performed. In the field of scientific publications, it is highly recommended that all researchers who wish to publish their studies get to know the good scientific practices and the basic ethical principles of publications in science. The vast majority of medical journals are guided by the recommendations of the International Committee of Medical Journal Editors (ICMJE) and with respect to ethical shortcomings, by the guidelines of the COPE (Committee on Ethics in Publications)...
July 2018: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
Alastair J S Webb
OBJECTIVES: Vasodilating antihypertensives prevent stroke and potentially cerebral small vessel disease but their effects on cerebrovascular haemodynamics beyond blood pressure lowering are unclear. METHODS: We searched PubMed, Medline, Embase, Cinahl, Psychinfo, Health Business Elite and Health Management Information Consortium for randomized studies of vasodilating medications, compared to no treatment or nonvasodilators, that reported effects on cerebral blood flow (CBF), mean blood flow velocity (MFV) or cerebrovascular reactivity...
December 11, 2018: Journal of Hypertension
Mikhail Khaimov, Jordan Fakhoury, Farhan Karim, Adam Bitterman, Scott Alpert
CASE: Isolated patella absentia is an extremely rare phenomenon, with only a few published cases and even fewer follow-up reports. Nearly 40 years after the initial presentation of 2 brothers with bilateral congenital absence of the patella and the publication of a case report, we report the clinical and radiographic findings of their subsequent tibiofemoral osteoarthritis, which was treated with bilateral total knee arthroplasty. CONCLUSION: Understanding the biomechanical complications associated with congenital absence of the patella as it relates to a stable knee is vital; in the case of degenerative changes, total knee arthroplasty appears to provide a long-term solution for these patients...
December 12, 2018: JBJS Case Connector
Cienwen J Town, James Johnson, André Van Zundert, Haakan Strand
OBJECTIVES: The review article was designed to assess the effectiveness of regional anesthesia, specifically peripheral nerve blocks, in the treatment of burn pain; with noting of clinical indications and contraindications for peripheral nerve block application, along with discussion of evidence-based analgesic strategies for providing improved, comprehensive burn pain management. METHODS: A search of relevant literature was performed using CINAHL, PubMed, EMBASE, Web of Science and SCOPUS with a publication date between January 2005 and December 2017...
December 11, 2018: Clinical Journal of Pain
Csaba Gaál
No abstract text is available yet for this article.
December 2018: Magyar Sebészet
(no author information available yet)
[This erratum is being published to correct a number of errors, including inaccurate references, on pages 380 and 383 of the following article:].
December 2018: Health Promotion and Chronic Disease Prevention in Canada
Jacqueline Galica, Alyssandra Chee-A-Tow, Shikha Gupta, Atul Jaiswal, Andrea Monsour, Andrea C Tricco, Kelly D Cobey, Nancy J Butcher
Background and purpose: Dissemination of research results is a key component of the research continuum and is commonly achieved through publication in peer-reviewed academic journals. However, issues of poor quality reporting in the research literature are well documented. A lack of formal training in journalology (i.e., publication science) may contribute to this problem. To help address this gap in training, the Enhancing the QUAlity and Transparency Of health Research (EQUATOR) Canada Publication School was developed and facilitated by internationally-renowned faculty to train researchers and clinicians in reporting and publication best practices...
2018: BMC Proceedings
Huma Ilyas, Ilyas Masih, Jan Peter van der Hoek
This paper investigates disinfection by-products (DBPs) formation and their relationship with governing factors in chlorinated swimming pools. The study compares concentrations of DBPs with WHO guidelines for drinking water quality recommended to screen swimming pool water quality. The statistical analysis is based on a global database of 188 swimming pools accumulated from 42 peer-reviewed journal publications from 16 countries. The mean and standard deviation of dichloroacetic acid and trichloroacetic acid were estimated as 282 ± 437 and 326 ± 517 μg L-1 , respectively, which most often surpassed the WHO guidelines...
December 2018: Journal of Water and Health
Bianca Marques Dos Santos, Rose Mary Costa Rosa Andrade Silva, Eliane Ramos Pereira, Fabiana Lopes Joaquim, Ticiane Roberta Pinto Goés
OBJECTIVE: To analyze the productions of knowledge about the students' perception of humanized care. METHOD: Study of bibliographical revision of the integrative type. The databases Pubmed, Lilacs, Cuiden and the SciELO virtual library were chosen for selection in October 2017, using the health descriptors "Students, Nursing", "Perception" and "Humanization of assistance", in the languages Portuguese, English and Spanish. RESULTS: Only eight studies were included that met the objectives of the study, where the majority portrays the Brazilian reality...
2018: Revista Brasileira de Enfermagem
Aline Dos Santos Sampaio, Matias Epifanio, Caroline Abud Drumond Costa, Vera Lúcia Bosa, Franceliane Jobim Benedetti, Edgar Enrique Sarria, Suelen Goecks Oliveira, Eduardo Mundstock, Rita Mattiello
This article aims to review systematically the evidence on nutritional assessment techniques and parameters used to determine the nutritional status of children and adolescents. The literature review and the selection of publications were performed using the Medline, Lilacs, SciELO, Embase, personal files. 17 studies were identified, 7 addressed the anthropometric indices as the main outcome, 7 analyzed the growth and development of children and adolescents through growth curves, and the remainder surveyed body composition...
December 2018: Ciência & Saúde Coletiva
Han Gao, Feng-Yan Huang, Zhi-Ping Wang
Background: Macrophage polarization is involved in the development of many diseases such as obesity, diabetes, and cancer. This study aimed to understand the trends and hotspots of macrophage polarization research. Methods: We searched through the Web of Science Core Collection database to obtain original articles in this research domain. CiteSpace, HistCite, and VOSviewer software were used to facilitate the analysis and visualization of scientific productivity and emerging trends...
December 20, 2018: Chinese Medical Journal
Chao Dai, Fan Zhou, Jiang-Hua Shao, Lin-Quan Wu, Xin Yu, Xiang-Bao Yin
Objective: Sorafenib, an oral vascular endothelial growth factor receptor tyrosine-kinase inhibitor, has become a cornerstone in the treatment of various malignancies. However, concerns have arisen regarding the risk of hemorrhage with sorafenib use. Nevertheless, the contribution of sorafenib to hemorrhage and the underlying risk factors remains unclear. Materials and Methods: We performed a meta-analysis to determine the incidence and risk of hemorrhage associated with sorafenib treatment...
December 2018: Journal of Cancer Research and Therapeutics
Rosa Martin-Mateos, Thiago M De Assuncao, Juan Pablo Arab, Nidhi Jalan-Sakrikar, Usman Yaqoob, Thomas Greuter, Vikas K Verma, Angela J Mathison, Sheng Cao, Gwen Lomberk, Philippe Mathurin, Raul Urrutia, Robert C Huebert, Vijay H Shah
BACKGROUND & AIMS: Transdifferentiation of hepatic stellate cells (HSCs) into myofibroblasts is a key event in the pathogenesis of liver fibrosis. Transforming growth factor β (TGF-β) and platelet-derived growth factor (PDGF) are canonical HSC activators after liver injury. The aim of this study was to analyze the epigenetic modulators that differentially control TGF-β and PDGF signaling pathways. METHODS: We performed a transcriptomic comparison of HSCs treated with TGF-β or PDGF-BB using RNA sequencing...
September 15, 2018: Cellular and Molecular Gastroenterology and Hepatology
Vinit Kumar Singh, Sneha Karmani, Palash Kumar Malo, H G Virupaksha, Daliboina Muralidhar, Ganesan Venkatasubramanian, Kesavan Muralidharan
BACKGROUND: Metabolic syndrome (MS) is reportedly associated with high mortality from mostly cardiovascular causes in patients with severe mental disorders (SMD). Lifestyle interventions augment effective management of MS in patients with SMD. The present meta-analysis aims at updating the recent evidence on the effectiveness of lifestyle intervention for MS in patients with SMD. METHOD: A literature search for English Language publications of randomized controlled trials (RCTs) from 2001 to 2016 comparing lifestyle modification (LM) with treatment as usual (TAU) in the management of MS were identified...
December 2018: Schizophrenia Research
Mate Vamos, Julia Wiebke Erath, Alexander Philipp Benz, Renato Delascio Lopes, Stefan Hans Hohnloser
In 2015, 3 independent meta-analyses raised concerns about digoxin therapy being associated with an increased mortality risk in patients with atrial fibrillation (AF) and with heart failure (HF). Although several other studies have been published since then fostering these safety issues, the most recent 2016 European guidelines for AF still recommend this therapy as a class I indication. We performed an updated systematic review and random-effect meta-analysis on publications up to March 2018 reporting data on digoxin associated mortality in subjects with AF or HF...
January 1, 2019: American Journal of Cardiology
Joanna Mader, Catherine Craig
We discuss the management of GBS positive women with PPROM, an aspect of obstetrical management that remains controversial despite the publication of new randomized control trials in recent years. Clinical practice guidelines from several countries' national organizations are compared and contrasted, and areas of uncertainty are identified.
December 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Lisa Ta, Laura Gosa, David A Nathanson
When it comes to biobanking and working with different types of laboratory specimens, it is important to understand potential biohazards to ensure safety of the operator and laboratory personnel. Biological safety levels (BSL) are a series of designations used to inform laboratory personnel about the level of biohazardous risks in a laboratory setting. There are a total of four levels ranked in order of increasing risk as stipulated by the Center of Disease Control and Prevention (CDC) (Biosafety in microbiological and biomedical laboratories, 5th edn...
2019: Methods in Molecular Biology
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