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https://www.readbyqxmd.com/read/28328632/use-of-processed-nerve-allografts-to-repair-nerve-injuries-greater-than-25-mm-in-the-hand
#1
Brian Rinker, Jozef Zoldos, Renata V Weber, Jason Ko, Wesley Thayer, Jeffrey Greenberg, Fraser J Leversedge, Bauback Safa, Gregory Buncke
Processed nerve allografts (PNAs) have been demonstrated to have improved clinical results compared with hollow conduits for reconstruction of digital nerve gaps less than 25 mm; however, the use of PNAs for longer gaps warrants further clinical investigation. Long nerve gaps have been traditionally hard to study because of low incidence. The advent of the RANGER registry, a large, institutional review board-approved, active database for PNA (Avance Nerve Graft; AxoGen, Inc, Alachua, FL) has allowed evaluation of lower incidence subsets...
March 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28325428/complete-section-of-proper-palmar-digital-pedicles-correlation-between-arterial-patency-and-sensory-recovery
#2
G Pomares, F Dap, G Dautel
Wounds to proper palmar digital (PPD) pedicles are frequent surgical emergencies. A correlation between arterial patency and nerve regeneration, however, has never been demonstrated. Forty-seven patients presenting complete section of a PPD pedicle and having undergone surgical repair of both elements were followed-up at a minimum of one year postoperatively. Doppler ultrasound examination studied arterial patency as well as the degree of stenosis. Neurological examination determined the BMRC score and the existence of cold intolerance, symptomatic neuroma and neurogenic pain...
April 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28319458/quality-of-life-in-807-patients-with-vestibular-schwannoma-comparing-treatment-modalities
#3
Géke Soulier, Bibian M van Leeuwen, Hein Putter, Jeroen C Jansen, Martijn J A Malessy, Peter Paul G van Benthem, Andel G L van der Mey, Anne M Stiggelbout
Objective In vestibular schwannoma treatment, the choice among treatment modalities is controversial. The first aim of this study was to examine the quality of life of patients with vestibular schwannoma having undergone observation, radiation therapy, or microsurgical resection. The second aim was to examine the relationship between perceived symptoms and quality of life. Last, the association between quality of life and time since treatment was studied. Study Design Cross-sectional study. Setting Tertiary referral center...
March 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28296312/two-year-experience-with-the-commercial-gamma-knife-check-software
#4
Andy Yuanguang Xu, Jagdish Bhatnagar, Greg Bednarz, Josef Novotny, John Flickinger, L Dade Lunsford, M Saiful Huq
The Gamma Knife Check software is an FDA approved second check system for dose calculations in Gamma Knife radiosurgery. The purpose of this study was to evaluate the accuracy and the stability of the commercial software package as a tool for independent dose verification. The Gamma Knife Check software version 8.4 was commissioned for a Leksell Gamma Knife Perfexion and a 4C unit at the University of Pittsburgh Medical Center in May 2012. Independent dose verifications were performed using this software for 319 radiosurgery cases on the Perfexion and 283 radiosurgery cases on the 4C units...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28293490/regenerative-peripheral-nerve-interfaces-for-the-treatment-of-postamputation-neuroma-pain-a-pilot-study
#5
Shoshana L Woo, Theodore A Kung, David L Brown, James A Leonard, Brian M Kelly, Paul S Cederna
BACKGROUND: Originally designed for prosthetic control, regenerative peripheral nerve interfaces (RPNIs) prevent neuroma formation by providing free muscle grafts as physiological targets for peripheral nerve ingrowth. We report the first series of patients undergoing RPNI implantation for treatment of symptomatic postamputation neuromas. METHODS: A retrospective case series of all amputees undergoing RPNI implantation for treatment of symptomatic neuromas between November 2013 and June 2015 is presented...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28265395/orbital-rhabdomyosarcoma-and-traumatic-neuroma-following-enucleation-for-a-uveal-schwannoma-in-a-dog-a-case-report
#6
Jessica E McDonald, Amy M Knollinger, Leandro B Teixeira, Richard R Dubielzig
A 4-year-old, female spayed Siberian husky with history of a uveal schwannoma presented for orbital swelling 9 months after enucleation. A second, malignant tumor developed in the same orbit. Therefore, uveal schwannomas may warrant early surgical intervention in the dog.
March 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28264236/influencing-factors-analysis-of-facial-nerve-function-after-the-microsurgical-resection-of-acoustic-neuroma
#7
WenMing Hong, HongWei Cheng, XiaoJie Wang, ChunGuo Feng
OBJECTIVE: To explore and analyze the influencing factors of facial nerve function retainment after microsurgery resection of acoustic neurinoma. METHODS: Retrospective analysis of our hospital 105 acoustic neuroma cases from October, 2006 to January 2012, in the group all patients were treated with suboccipital sigmoid sinus approach to acoustic neuroma microsurgery resection. We adopted researching individual patient data, outpatient review and telephone followed up and the House-Brackmann grading system to evaluate and analyze the facial nerve function...
March 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28260461/traumatic-neuroma-causing-biliary-stricture-after-orthotopic-liver-transplant-treated-with-hepaticojejunostomy-a-case-report
#8
Aysen Terzi, Mahir Kirnap, Cigdem Sercan, Gokce Ozdemir, Binnaz Handan Ozdemir, Mehmet Haberal
Traumatic neuromas of the biliary tract have occasionally been reported to cause strictures at the cystic duct stump as a late complication of cholecystectomy with common bile duct exploration. The incidence of symptomatic traumatic biliary neuroma appears to be low after orthotopic liver transplant, as only 25 patients have been described previously in the English-language literature. Traumatic (amputation) neuroma is a reactive proliferation of pericholangial nerve fibers induced by injury, but it is not a true neoplasm...
February 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28258282/evaluation-of-auditory-pathways-using-dti-in-patients-treated-with-gamma-knife-radiosurgery-for-acoustic-neuroma-a%C3%A2-preliminary-report
#9
Serpil Kurtcan, Mustafa Aziz Hatiboglu, Alpay Alkan, Huseyin Toprak, Mehmet Hakan Seyithanoglu, Ayse Aralasmak, Bahar Atasoy, Omer Uysal
PURPOSE: We aimed to evaluate the change in bilateral auditory pathways using diffusion tensor imaging (DTI) after gamma knife radiosurgery (GKR) and to determine the relationship between the radiosurgical treatment variables and DTI findings. METHODS: In this study 13 patients with unilateral acoustic neuroma and 11 controls underwent routine magnetic resonance imaging (MRI) and DTI. The apparent diffusion coefficient (ADC) and fractional anisotropy (FA) were measured from the bilateral auditory pathways in all individuals before and after GKR...
March 3, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28249977/the-role-of-the-width-of-the-forefoot-in-the-development-of-morton-s-neuroma
#10
Y H Park, S M Jeong, G W Choi, H J Kim
AIMS: Morton's neuroma is common condition of the forefoot, but its aetiology remains unclear. Our aim was to evaluate the relationship between the width of the forefoot and the development of a Morton's neuroma. PATIENTS AND METHODS: Between January 2013 and May 2016, a total of 84 consecutive patients (17 men, 67 women) with a unilateral Morton's neuroma were enrolled into the study. The involved and uninvolved feet of each patient were compared. A control group of patients with symptoms from the foot, but without a neuroma who were matched for age, gender, affected side, and web space location, were enrolled...
March 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28239543/endobronchial-neurogenic-tumor-a-combination-of-traumatic-neuroma-and-neurofibroma
#11
Amit Tandon
Traumatic neuromas are uncommon and benign lesions arising from a peripheral nerve injury during surgery. Here we describe a case with histopathologic features of both a traumatic neuroma and neurofibroma in a patient without integumentary physical exam findings nor prior surgical history. A 54 year old male was admitted for surgical debridement of a foot ulcer. During pre-operative evaluation and review of imaging multiple CT scans revealed a stable, 4 mm endobronchial lesion in the left lower lobe. Given history of nicotine abuse, bronchoscopy was performed...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28237081/incidence-of-posterior-interosseous-nerve-trauma-during-creation-of-the-3-4-wrist-arthroscopy-portal-in-cadavers
#12
Andre Eu-Jin Cheah, Wei Le, Jeffrey Yao
PURPOSE: To describe histologic evidence of nerve trauma during the creation and use of the 3-4 portal. METHODS: Fourteen fresh-frozen cadaveric wrists were mounted on a custom-built frame that simulated a wrist arthroscopy traction tower. After the 3-4 portal was created in the usual manner, the skin was dissected off to identify possible trauma to the posterior interosseous nerve (PIN). Specimens were categorized into those where there was clearly no trauma to the PIN and those where trauma was possible...
February 22, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28235631/clinicopathologic-features-of-peripheral-nerve-sheath-tumors-involving-the-eye-and-ocular-adnexa
#13
Mingjuan L Zhang, Maria J Suarez, Thomas M Bosley, Fausto J Rodriguez
Peripheral nerve sheath tumors (PNSTs) are known to occur in the orbit and comprise 4% of all orbital tumors, but have not been well-studied in contemporary literature. Ninety specimens involving the eye and ocular adnexa (1979-2015) from 67 patients were studied. The mean age was 32.5years. Locations included orbit (58.9%), eyelid (60.0%) and other ocular adnexa. A large majority of specimens were neurofibromas (70.0%), followed by schwannomas (11.1%), neuromas (11.1%), granular cell tumors (n=4), nerve sheath myxomas (n=2), and malignant peripheral nerve sheath tumor (n=1)...
February 21, 2017: Human Pathology
https://www.readbyqxmd.com/read/28224625/the-effects-of-venous-ensheathment-on-facial-nerve-repair-in-the-rat
#14
Pei Chen, Christopher J Knox, Linli Yao, Chunli Li, Tessa A Hadlock
OBJECTIVE: To investigate the protective effect of autologous venous ensheathment on sutured rat facial nerve and to test whether the ensheathment could improve the functional recovery of repaired nerve and accuracy of axonal growth. STUDY DESIGN: In vivo study. METHODS: Forty-six rats were examined, with six rats serving as normal controls and 40 receiving facial nerve transection and suture repair (SR) or transection and suture repair with an additional venous ensheathment (VE)...
February 22, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28223839/ultrasound-guided-alcohol-neurolysis-and-radiofrequency-ablation-of-painful-stump-neuroma-effective-treatments-for-post-amputation-pain
#15
Xin Zhang, Yongming Xu, Jin Zhou, Shaofeng Pu, Yingying Lv, Yueping Chen, Dongping Du
BACKGROUND: Post-amputation pain (PAP) is highly prevalent after limb amputation, and stump neuromas play a key role in the generation of the pain. Presently, PAP refractory to medical management is frequently treated with minimally invasive procedures guided by ultrasound, such as alcohol neurolysis and radiofrequency ablation (RFA). OBJECTIVE: To record the immediate and long-term efficacy of alcohol neurolysis and RFA. We first used alcohol neurolysis and then, when necessary, we performed RFA on PAP patients...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28216859/prevalence-of-phantom-limb-pain-stump-pain-and-phantom-limb-sensation-among-the-amputated-cancer-patients-in-india-a-prospective-observational-study
#16
Arif Ahmed, Sushma Bhatnagar, Seema Mishra, Deepa Khurana, Saurabh Joshi, Syed Mehmood Ahmad
INTRODUCTION: The phantom limb pain (PLP) and phantom limb sensation (PLS) are very common among amputated cancer patients, and they lead to considerable morbidity. In spite of this, there is a lack of epidemiological data of this phenomenon among the Asian population. This study was done to provide the data from Indian population. METHODS: The prevalence of PLP, stump pain (SP), and PLS was prospectively analyzed from the amputated cancer patients over a period of 2 years in Dr...
January 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/28197545/active-nerve-regeneration-with-failed-target-reinnervation-drives-persistent-neuropathic-pain
#17
Wenrui Xie, Judith A Strong, Jun-Ming Zhang
Peripheral nerves can regenerate and, when injured, may cause neuropathic pain. We propose that the active regeneration process plays a pivotal role in the maintenance of neuropathic pain. In one commonly used rodent neuropathic pain model, pronounced pain behaviors follow ligation and cutting of the L5 spinal nerve. We found that the injured nerve regenerates into the sciatic nerve and functionally reinnervates target tissues: the regenerated nerve conducts electrical signals, mechanical responses, and tracers between the leg/hindpaw and axotomized sensory ganglion...
January 2017: ENeuro
https://www.readbyqxmd.com/read/28187056/operative-mortality-rates-of-acoustic-neuroma-surgery-a-national-cancer-database-analysis
#18
Shearwood McClelland, Ellen Kim, James D Murphy, Jerry J Jaboin
INTRODUCTION: Optimal acoustic neuroma (AN) management involves choosing between three treatment modalities: microsurgical excision, radiation, or observation with serial imaging. The reported in-hospital mortality rate of surgery for AN in the United States is 0.5%. However, there has yet to be a nationwide examination of the AN surgery mortality rate encompassing the period beyond initial hospital discharge. METHODS: The National Cancer Data Base (NCDB) from 2004 to 2013 identified AN patients receiving surgery...
February 9, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28178983/management-of-painful-clitoral-neuroma-after-female-genital-mutilation-cutting
#19
Jasmine Abdulcadir, Jean-Christophe Tille, Patrick Petignat
BACKGROUND: Traumatic neuromas are the result of regenerative disorganized proliferation of the proximal portion of lesioned nerves. They can exist in any anatomical site and are responsible for neuropathic pain. Post-traumatic neuromas of the clitoris have been described as an uncommon consequence of female genital mutilation/cutting (FGM/C). FGM/C involves partial or total removal of the female genital organs for non-therapeutic reasons. It can involve cutting of the clitoris and can cause psychological, sexual, and physical complications...
February 8, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28178141/a-non-surgical-approach-to-the-management-of-exposure-keratitis-due-to-facial-palsy-by-using-mini-scleral-lenses
#20
Victor Zaki
RATIONALE: This is a retrospective study aimed to determine the efficacy of mini-scleral contact lens in protecting the cornea and improving vision in cases of facial palsy. PATIENT CONCERNS: Patients with facial palsy get exposure keratitis because the cornea is dry. They feel pain, discomfort and excessive watering. If left untreated, it leads to permanent damage to the cornea and loss of good functional vision. Mini-scleral lens keep the cornea covered by saline solution all wearing hours...
February 2017: Medicine (Baltimore)
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