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XiDa Liang, Yi Wang, LiMei Liu, Meng Gao, YanPing Yu, ZengYi Wang, JinQiu Chen, XinXin Liu, Wu Liu
BACKGROUND AND OBJECTIVE: To investigate changes in the pattern of metamorphopsia in patients after idiopathic macular hole (MH) surgery and the relationship between metamorphopsia, visual acuity (VA), and macular parameters. PATIENTS AND METHODS: This prospective, interventional study included 53 eyes of 53 patients with idiopathic full-thickness MH. The severity of metamorphopsia was quantified using M-CHARTs. Minimal and basal diameter of MH and disrupted length of ellipsoid zone were measured using spectral-domain optical coherence tomography...
August 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Jianbo Mao, Dong Fang, Yiqi Chen, Jiwei Tao, Mengai Wu, Sulan Wu, Pengfei Wang, Yun Zhang, Lijun Shen
BACKGROUND AND OBJECTIVE: To investigate the predictive factors of visual acuity (VA) after cataract surgery in patients with retinitis pigmentosa (RP). PATIENTS AND METHODS: Retrospective, observational study. The authors reviewed a consecutive series of 70 patients (109 eyes) with RP who underwent cataract surgery. The changes in best-corrected visual acuity (BCVA) before and 3 months after surgery were measured. The relationship between preoperative ellipsoid zone (EZ) conditions, external limiting membrane (ELM) conditions, central macular thickness (CMT), and postoperative BCVA were investigated...
August 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Mumin Hocaoglu, Isil Sayman Muslubas, M Giray Ersoz, Serra Arf, Murat Karacorlu
BACKGROUND AND OBJECTIVE: To report anatomical and functional outcomes of surgery in each of the eyes in cases of bilateral macular hole (MH). PATIENTS AND METHODS: The anatomical and functional results for 42 patients with bilateral idiopathic MH were evaluated retrospectively. First-operated and fellow eyes were compared at various time points for preoperative characteristics and postoperative outcomes. RESULTS: Anatomical success was achieved in all patients after a single operation, and no reopening of an initially closed MH was observed during the follow-up period...
August 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Alec L Amram, Murtaza M Mandviwala, William C Ou, Charles C Wykoff, Ankoor R Shah
BACKGROUND AND OBJECTIVE: To investigate predictors of visual outcomes in patients who underwent vitrectomy for full-thickness macular hole (FTMH) with at least 1 year of follow-up. PATIENTS AND METHODS: Retrospective, noncomparative, consecutive case series of 132 eyes of 122 patients who underwent surgical repair of idiopathic FTMH with at least 1 year of follow-up. Predictors of visual acuity (VA) outcomes were analyzed using linear regression. RESULTS: Mean follow-up time was 22...
August 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Alex H S Harris, Alfred C Kuo, Kevin J Bozic, Edmund Lau, Thomas Bowe, Shalini Gupta, Nicholas J Giori
BACKGROUND: The American Joint Replacement Registry (AJRR) Total Joint Risk Calculator uses demographic and clinical parameters to provide risk estimates for 90-day mortality and 2-year periprosthetic joint infection (PJI). The tool is intended to help surgeons counsel their Medicare-eligible patients about their risk of death and PJI after total joint arthroplasty (TJA). However, for a predictive risk model to be useful, it must be accurate when applied to new patients; this has yet to be established for this calculator...
September 2018: Clinical Orthopaedics and related Research
Jiabing Huang, Pengfei Chen, Xinqun Hu, Jianjun Tang, Zhenfei Fang
RATIONALE: Cardiogenic shock secondary to aortic stenosis (AS) is a challenging problem owing to the high mortality associated with treatment, and successful treatment of such patients has been rare. PATIENT CONCERNS: A 77-year-old man presented with exercise intolerance and progressive exertional dyspnea and chest pain. The patient was suffered from cardiogenic shock after percutaneous coronary intervention. DIAGNOSIS: He was diagnosed by transthoracic echocardiography (TTE) and coronary angiogram...
August 2018: Medicine (Baltimore)
Dirk W Donker, Daniel Brodie, José P S Henriques, Michael Broomé
Short-term mechanical support by veno-arterial extracorporeal membrane oxygenation (VA ECMO) is more and more applied in patients with severe cardiogenic shock. A major shortcoming of VA ECMO is its variable, but inherent increase of left ventricular (LV) mechanical load, which may aggravate pulmonary edema and hamper cardiac recovery. In order to mitigate these negative sequelae of VA ECMO, different adjunct LV unloading interventions have gained a broad interest in recent years. Here, we review the whole spectrum of percutaneous and surgical techniques combined with VA ECMO reported to date...
August 16, 2018: Perfusion
Wen-Zhi Xiao, Gang Xiao, Qing-Yan Rong, Ling-Ling Wang
Auxetic materials, which possess a negative Poisson's ratio (NPR), have been a hot topic in materials science research. Through atomistic simulations, we theoretically rediscover a few novel two-dimensional (2D) VA-nitride (VA-N) binary compounds with δ-phosphorene-like structures. The structures in the δ-phase (except for δ-PN) exhibit better stability in terms of energy, thermodynamics, and mechanics with respect to their counterparts in the α- and β-phases. The structures in the δ-phase show semiconducting behaviors with direct band gaps falling in the visible light region...
August 16, 2018: Physical Chemistry Chemical Physics: PCCP
Alexander Robinson, Aniket S Rali, Zubair Shah, Travis Abicht, Eric Hockstad, Andrew Sauer
National trends suggest that less than one in four patients experiencing in-hospital cardiac arrest (IHCA) in the United States survive to discharge. This is especially relevant as the rates of IHCA are expected to rise in the years to come. Only a modest upward trend in survival to discharge among patients with IHCA over the past decade warrants evaluation of novel ideas to improve outcomes postcardiopulmonary resuscitation. One such idea is that the use of veno-arterial-extracorporeal membrane oxygenation (VA-ECMO) to augment standard advanced cardiac life support algorithm in patients with an identifiable and reversible cause of cardiac arrest would improve survival to discharge...
July 2018: Indian Journal of Critical Care Medicine
Yih-Chung Tham, Sing-Hui Lim, Yuan Shi, Miao-Li Chee, Ying Feng Zheng, Jacqueline Chua, Seang-Mei Saw, Paul Foster, Tin Aung, Tien Yin Wong, Ching-Yu Cheng
We evaluated the prevalence of visual impairment (VI) and blindness among Chinese adults in the Singapore Chinese Eye Study (SCES, 2009-2011), and compared the trends with the Tanjong Pagar Survey, Singapore (TPS), conducted a decade earlier. The SCES comprised of 3,353 Chinese adults aged ≥40 years (response rate, 72.8%). Participants underwent standardized examinations, including measurements of presenting, and best-corrected visual acuity (VA). Bilateral VI (VA < 20/40 to ≥20/200) and blindness (VA < 20/200) were defined based on the United States definition (better-seeing eye)...
August 15, 2018: Scientific Reports
Jolie Haun, Margeaux Chavez, Wendy Hathaway, Nicole Antinori, Christine Melillo, Bridget A Cotner, Julie McMahon-Grenz, Brian Zilka, Shilpa Patel-Teague, William Messina, Kim Nazi
BACKGROUND: The Veterans Health Administration (VHA) is making system-wide efforts to increase integrated use of health information technology (HIT), including My HealtheVet (MHV), the Veterans Affairs (VA) electronic patient portal, Vet Link kiosks, telehealth, and mobile apps. Integrated use of HIT can increase individual and system efficiency, maximize resources, and enhance patient outcomes. Prior research indicates that provider endorsement and reinforcement are key determinants of patient adoption of HIT...
August 15, 2018: JMIR Research Protocols
Jeffrey M Pyne, Aline Rabalais, Steve Sullivan
Moral injury in veterans with posttraumatic stress disorder includes symptoms of guilt and shame, and these symptoms are often not responsive to evidence-based mental health treatments. Clergy provide a pathway for relieving the guilt and shame. However, there is a long history of mistrust between clergy and mental health clinicians and not enough Veterans Health Administration chaplains to meet this need. The goal of this study was to gather qualitative interview data from relevant stakeholders regarding whether and how Veterans Affairs (VA) mental health clinicians and community clergy could collaborate to address moral injury issues such as guilt and shame in veterans being treated for posttraumatic stress disorder...
August 15, 2018: Journal of Health Care Chaplaincy
Clemente Paz-Filgueira, Elisa M Colombo
The visual performance of a reference group (RG) using diffuser filters was compared to a cataract-diagnosed group (CatG). Measurements of straylight (SL) parameter, photopic contrast sensitivity (CS), and visual acuity (VA) were carried out in both groups. Before the analysis, the performance of the instruments used for this purpose was tested. The RG was comprised of three healthy, young eyes (25-30 years old) while 59 subjects (aged 50-80 years old) with lens opacities were recruited for the CatG. Six diffuser conditions were tested in the RG...
July 1, 2018: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
José Gustavo Padrão Tavares, Paolo Ruggero Errante, Tânia Carmem Peñaranda Govato, Ênio Rodrigues Vasques, Renato Ribeiro Nogueira Ferraz, Murched Omar Taha, Francisco Sandro Menezes-Rodrigues, Afonso Caricati-Neto
PURPOSE: To investigate the cardioprotective effects of ischemic preconditioning (preIC) and postconditioning (postIC) in animal model of cardiac ischemia/reperfusion. METHODS: Adult rats were submitted to protocol of cardiac ischemia/reperfusion (I/R) and randomized into three experimental groups: cardiac I/R (n=33), preCI + cardiac I/R (n=7) and postCI + cardiac I/R (n=8). After this I/R protocol, the incidence of ventricular arrhythmia (VA), atrioventricular block (AVB) and lethality (LET) was evaluated using the electrocardiogram (ECG) analysis...
July 2018: Acta Cirúrgica Brasileira
Theresa Nguyen Wenker, Mimi C Tan, Yan Liu, Hashem B El-Serag, Aaron P Thrift
BACKGROUND: Efforts to reduce mortality from esophageal adenocarcinoma (EA) have focused on screening and surveillance of Barrett's esophagus (BE). AIMS: We sought to determine the frequency of prior diagnosis of BE in patients with EA and to evaluate the impact of a prior BE diagnosis on mortality in EA patients. METHODS: This was a retrospective cohort study of patients diagnosed with EA in the VA during 2002-2016. We compared the distributions of EA stage and receipt of treatment between EA patients with and without a prior BE diagnosis and used Cox proportional hazards models to compare mortality risk (all-cause and cancer specific) unadjusted and adjusted for stage and treatment to assess their impact on any survival differences...
August 14, 2018: Digestive Diseases and Sciences
Christopher R Williams, Angela Jellison, Luke Martin, Chong Zhang, Angela P Presson, Larry W Kraiss, Benjamin S Brooke
OBJECTIVE: Optimizing medical management through glucose control, smoking cessation, and drug therapy (ie, antiplatelet and statin agents) is recommended as first-line therapy for patients with claudication. The aims of this study were to determine how frequently veterans with claudication received optimal medical management (OMM) before undergoing elective open lower extremity bypass procedures nationwide and whether preoperative OMM was associated with improved surgical outcomes. METHODS: We reviewed all patients within the Veterans Affairs (VA) Surgical Quality Improvement Program database who underwent elective open lower extremity bypass procedures for claudication at nationwide VA medical centers from 2005 until 2015...
August 11, 2018: Journal of Vascular Surgery
Jeffrey P Gordon, Jackson J Liang, Rajeev Pathak, Erica S Zado, Fermin C Garcia, Matthew D Hutchinson, Pasquale Santangeli, Robert D Schaller, David S Frankel, Francis E Marchlinski, Gregory E Supple
BACKGROUND: Catheter ablation of ventricular arrhythmias (VA) from the papillary muscles (PM) is challenging due to limited catheter stability and contact on the PMs with their anatomic complexity and mobility. OBJECTIVE: To evaluate the effectiveness of cryoablation as an adjunctive therapy for PM VAs when radiofrequency (RF) ablation has failed. METHODS: We evaluated a retrospective series of patients who underwent cryoablation for PM VAs when RF ablation had failed...
August 14, 2018: Journal of Cardiovascular Electrophysiology
Jason J Sico, Fitsum Baye, Laura J Myers, John Concato, Jared Ferguson, Eric M Cheng, Farid Jadbabaie, Zhangsheng Yu, Gregory Arling, Alan J Zillich, Mathew J Reeves, Linda S Williams, Dawn M Bravata
Background: American Heart Association/American Stroke Association expert consensus guidelines recommend consideration of cardiac stress testing to screen for occult coronary heart disease (CHD) among patients with ischemic stroke/TIA who have a high-risk Framingham Cardiac Risk Score (FCRS). Whether this guideline is being implemented in routine clinical practice, and the association of its implementation with mortality, is less clear. Methods: Study participants were Veterans with stroke/TIA (n = 11,306) during fiscal year 2011 who presented to a VA Emergency Department or who were admitted...
June 2018: Neurology. Clinical Practice
Zhen Yang, Shi Gu, Nicolas Honnorat, Kristin A Linn, Russell T Shinohara, Irem Aselcioglu, Steven Bruce, Desmond J Oathes, Christos Davatzikos, Theodore D Satterthwaite, Danielle S Bassett, Yvette I Sheline
Despite widespread use of cognitive behavioral therapy (CBT) in clinical practice, its mechanisms with respect to brain networks remain sparsely described. In this study, we applied tools from graph theory and network science to better understand the transdiagnostic neural mechanisms of this treatment for depression. A sample of 64 subjects was included in a study of network dynamics: 33 patients (15 MDD, 18 PTSD) received longitudinal fMRI resting state scans before and after 12 weeks of CBT. Depression severity was rated on the Montgomery-Asberg Depression Rating Scale (MADRS)...
August 13, 2018: Molecular Psychiatry
Tracy A Becerra-Culqui, Darios Getahun, Vicki Chiu, Lina S Sy, Hung Fu Tseng
: media-1vid110.1542/5803567555001PEDS-VA_2018-0120 Video Abstract BACKGROUND: Increasing vaccination of pregnant women makes it important to assess safety events potentially linked to prenatal vaccination. This study investigates the association between prenatal tetanus, diphtheria, acellular pertussis (Tdap) vaccination and autism spectrum disorder (ASD) risk in offspring. METHODS: This is a retrospective cohort study of mother-child pairs with deliveries January 1, 2011 to December 31, 2014 at Kaiser Permanente Southern California hospitals...
August 13, 2018: Pediatrics
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