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Danielle A J M Schoenaker, Emily Brennan, Melanie A Wakefield, Sarah J Durkin
BACKGROUND: Social denormalisation of smoking can provide an environment that helps smokers to quit. This study examined which of three measures of anti-smoking social norms have the greatest influence on quitting-related cognitions and behaviours, and if this influence differs according to socioeconomic status (SES). METHODS: The Victorian Tracking Survey measured social norms among 1,348 (n(weighted) = 1,373) Australian adult smokers (aged 18-59) between 2012 and 2014, who were followed-up one week later...
2018: PloS One
Elzo Pereira Pinto Junior, Líllian de Queiroz Costa, Silvia Morgana Araujo de Oliveira, Maria Guadalupe Medina, Rosana Aquino, Marcelo Gurgel Carlos da Silva
This study analyses expenditure trends in Hospitalizations for Ambulatory Care Sensitive Conditions (ACSCs) in children. It is an ecological time-series study, including hospitalizations of children under five in Bahia, between 2000 and 2012. We calculate the annual ACSC rates, as well as the total and average expenditure on these hospitalizations. We construct linear regression analysis models for the temporal trends. Between 2000 and 2012, 810,831 ACSC hospitalizations for the under-fives were recorded in Bahia...
December 2018: Ciência & Saúde Coletiva
Shree Ram Lamichhane, Thanuja Thachil, Paolo De Ieso, Harriet Gee, Simon Andrew Moss, Natalie Milic
Background: MicroRNAs (miRNAs) have been found to play an important role in the development and outcomes for multiple human cancers. Their role as a prognostic biomarker in non-small-cell lung cancer (NSCLC) remains unclear. This meta-analysis aims to clarify the role of various miRNAs in the survival of NSCLC patients. Materials and Methods: All studies were identified through medical database search engines. A meta-analysis was conducted to assess the correlation between miRNAs expressions and overall survival among those NSCLC studies...
2018: Disease Markers
Miao Zhang, Allison F Gillaspy, Jenny R Gipson, Benjamin R Cassidy, Jessica L Nave, Misty F Brewer, Julie A Stoner, Jie Chen, Douglas A Drevets
MicroRNA (miR) miR-155 modulates microglial activation and polarization, but its role in activation of microglia during bacterial brain infection is unclear. We studied miR-155 expression in brains of C57BL/6 (B6.WT) mice infected i.p. with the neuro-invasive bacterial pathogen Listeria monocytogenes ( L. monocytogenes ). Infected mice were treated with ampicillin starting 2 days (d) post-infection (p.i.) and analyzed 3d, 7d, and 14d p.i. Virulent L. monocytogenes strains EGD and 10403s upregulated miR-155 in whole brain 7 d p...
2018: Frontiers in Immunology
Yu Hashimoto, Hidenori Ogata, Ryo Yamasaki, Takakazu Sasaguri, Senri Ko, Kenichiro Yamashita, Zhang Xu, Takuya Matsushita, Takahisa Tateishi, Shin'ichi Akiyama, Shoichi Maruyama, Akifumi Yamamoto, Jun-Ichi Kira
Background: Several case reports have described the concurrence of chronic inflammatory demyelinating polyneuropathy (CIDP) and membranous nephropathy (MN). The presence of autoantibodies against podocyte antigens phospholipase A2 receptor (PLA2R) and thrombospondin type 1 domain containing 7A (THSD7A) in MN suggests an autoimmune mechanism. Some CIDP patients also harbor autoantibodies against paranodal proteins such as neurofascin 155 (NF155) and contactin-1 (CNTN1). We investigated the relationship between CIDP and MN by assaying autoantibodies against paranodal and podocyte antigens in a CIDP patient with MN, and by a literature survey on the clinical features of CIDP with MN...
2018: Frontiers in Neurology
Jonathan L Dunnum, Bryan S McLean, Robert C Dowler
As a periodic assessment of the mammal collection resource, the Systematic Collections Committee (SCC) of the American Society of Mammalogists undertakes decadal surveys of the collections held in the Western Hemisphere. The SCC surveyed 429 collections and compiled a directory of 395 active collections containing 5,275,155 catalogued specimens. Over the past decade, 43 collections have been lost or transferred and 38 new or unsurveyed collections were added. Growth in number of total specimens, expansion of genomic resource collections, and substantial gains in digitization and web accessibility were documented, as well as slight shifts in proportional representation of taxonomic groups owing to increasingly balanced geographic representation of collections relative to previous surveys...
December 5, 2018: Journal of Mammalogy
Xiaohui Zhou, Ying Tian, Xiao Liu, Liping Huang, Yang Wen
  In this study, imidacloprid was degraded by sponge iron in aqueous solution via chemical reduction. The effects of initial pH, reaction time, and operating model were investigated. Lower of pH was advantageous to the reduction degradation reaction. The influence of agitation was investigated in terms of reaction kinetics and degradation yield. Imidacloprid degradation with agitation showed first-order reaction kinetics with a reaction rate of 0.0235 min-1 , and degradation without agitation possessed two distinctive kinetics regimes; a rapid reduction in the initial stage and a slower process until removal was complete...
December 1, 2018: Water Environment Research: a Research Publication of the Water Environment Federation
Jonathan Yip, Weibo Hao, Antoine Eskander, John M Lee
BACKGROUND: Previous studies on the impact of wait times for endoscopic sinus surgery (ESS) in medically recalcitrant chronic rhinosinusitis (rCRS) have not examined its influence on the 5 distinct symptoms domains of the 22-item Sino-Nasal Outcome Test (SNOT-22), and have not applied evidence-based surgical indications. Our primary study objective was to investigate the impact of ESS wait times on postoperative SNOT-22 global and symptom domain scores in patients with rCRS deemed "appropriate" surgical candidates...
December 10, 2018: International Forum of Allergy & Rhinology
S Lu, Q-S Liao, L Tang
OBJECTIVE: Osteosarcoma can form tumor osteoid tissue and bone tissue directly or indirectly through cartilage stage. It mainly occurs in children and adolescents with high mortality. MicroRNA (miRNA) possesses tissue sensitivity as tumor biomarker and plays a promoting or inhibitory role in tumor pathogenesis as oncogene or tumor suppressor gene. It was found that miR-155 was abnormally expressed in tumor and could be treated as a biomarker for cancer progression. However, miR-155 expression in osteosarcoma and related mechanism still remains unclear...
November 2018: European Review for Medical and Pharmacological Sciences
Ahmet Eser, Enis Ozkaya, Cigdem Yayla Abide, Tugba Eser, Gulcin Yildirim Eser, Faruk Abike, Ahter Tanay Tayyar, Mustafa Eroglu
PURPOSE: To analyze the effect of combined application of intravaginal PGE2 insert and intracervical Foley balloon catheter for induction of labor. METHODS: Patients with unfavorable cervices who required induction of labor from August 2017 to December 2017 were evaluated for the study. Three hundred and ten participants were randomly assigned to study (n:155) and control group (n:155). Nine patients in study group and seven patients in control group were excluded, because they declined to participate in the study...
December 7, 2018: Archives of Gynecology and Obstetrics
Joong-Myung Lee, Young-Suk Sim, Dae-Sung Choi
Purpose: This is a report on the outcomes associated with a consecutive series of 1,000 cementless hip arthroplasties utilizing the Bencox® hip stem-the first Korean-developed hip prosthesis. Materials and Methods: A consecutive series of 1,000 hip arthroplasties using the Bencox® hip stem were analyzed, starting from its initial release (September 2006) until June 2014. Patients in this consecutive series underwent surgery for fractures (n=552), arthritis (n=155), avascular necrosis (n=209), and revisions (n=84)...
December 2018: Hip & Pelvis
Kayla M Fast, Tracy W Keener, Shane Castleberry, Kenny D Jones, John D Larrimore, Caitlin A Long, Jon T Newburn, Nicholas C Pritchett, P Kiersten Schellhammer, Michael W Sandel
Bacteriophages Kwksand96 and Cane17 were isolated from Mycobacterium smegmatis mc2 155. M. smegmatis is host to the highest number of phages analyzed from one species. Both mycobacteriophages were isolated from soil in west Alabama. Kwksand96 and Cane17 belong to subclusters B1 and C1, respectively, based on mycobacteriophage nucleotide sequence similarity.
November 2018: Microbiology resource announcements
Slimane Choubane, Noujoud Gabed, Omar Khelil, Ben Amar Cheba
In this paper, we report Bacillus subtilis TLO3, which was isolated from olive tree rhizosphere and exhibits high amylolytic activity. The genome of Bacillus subtilis TLO3 contains 4,071 protein-coding sequences carried on one chromosome (4,232,155 bp) with an average G+C content of 44.1% and 119 RNA molecules. The gene encoding α-amylase was detected, as well as other genes related to starch and cellulose hydrolysis, making the strain a potential candidate for industrial treatment of starch and lignocellulose biomasses...
September 2018: Microbiology resource announcements
Stephen Taylor, Ming Fang
This article develops unbiased weighted variance and skewness estimators for overlapping return distributions. These estimators extend the variance estimation methods constructed in Bod et. al. (Applied Financial Economics 12:155-158, 2002) and Lo and MacKinlay (Review of Financial Studies 1:41-66, 1988). In addition, they may be used in overlapping return variance or skewness ratio tests as in Charles and Darné (Journal of Economic Surveys 3:503-527, 2009) and Wong (Cardiff Economics Working Papers, 2016)...
2018: Swiss journal of economics and statistics
Eric A Franzosa, Alexandra Sirota-Madi, Julian Avila-Pacheco, Nadine Fornelos, Henry J Haiser, Stefan Reinker, Tommi Vatanen, A Brantley Hall, Himel Mallick, Lauren J McIver, Jenny S Sauk, Robin G Wilson, Betsy W Stevens, Justin M Scott, Kerry Pierce, Amy A Deik, Kevin Bullock, Floris Imhann, Jeffrey A Porter, Alexandra Zhernakova, Jingyuan Fu, Rinse K Weersma, Cisca Wijmenga, Clary B Clish, Hera Vlamakis, Curtis Huttenhower, Ramnik J Xavier
The inflammatory bowel diseases (IBDs), which include Crohn's disease (CD) and ulcerative colitis (UC), are multifactorial chronic conditions of the gastrointestinal tract. While IBD has been associated with dramatic changes in the gut microbiota, changes in the gut metabolome-the molecular interface between host and microbiota-are less well understood. To address this gap, we performed untargeted metabolomic and shotgun metagenomic profiling of cross-sectional stool samples from discovery (n = 155) and validation (n = 65) cohorts of CD, UC and non-IBD control patients...
December 10, 2018: Nature Microbiology
Elizabeth G Clement, Sarah Horvath, Arden McAllister, Nathanael C Koelper, Mary D Sammel, Courtney A Schreiber
OBJECTIVE: To document the terminology patients hear during the treatment course for a nonviable pregnancy and to ask patients their perceived clarity and preference of terminology to identify a patient-centered lexicon. METHODS: We performed a preplanned substudy survey of English-speaking participants in New York, Pennsylvania, and California at the time of enrollment in a randomized multisite trial of medical management of first-trimester early pregnancy loss...
December 4, 2018: Obstetrics and Gynecology
Christopher W Liu, Anuj Bhatia, Arlene Buzon-Tan, Susan Walker, Dharini Ilangomaran, Jamal Kara, Lakshmikumar Venkatraghavan, Atul J Prabhu
BACKGROUND: The recreational and medical use of cannabinoids has been increasing. While most studies and reviews have focused on the role of cannabinoids in the management of acute pain, no study has examined the postoperative outcomes of surgical candidates who are on cannabinoids preoperatively. This retrospective cohort study examined the impact of preoperative cannabinoid use on postoperative pain scores and pain-related outcomes in patients undergoing major orthopedic surgery. METHODS: Outcomes of patients who had major orthopedic surgery at our hospital between April 1, 2015 and June 30, 2017 were reviewed...
December 7, 2018: Anesthesia and Analgesia
Shulan Qu, Yunhui Shen, Mengjie Wang, Xiaoyu Wang, Yifu Yang
Ulcerative colitis (UC) is a major form of inflammatory bowel disease which involved mucosal immune dysfunction. Cinnamaldehyde (CA) is major active compound from cinnamon, a useful traditional medicine in Asia which shows superior antibacterial and anti-inflammatory activity. In this study, we investigated the effects of CA on UC both in vivo and in vitro. We showed that CA attenuated the symptoms of DSS-induced colitis, including loss of body weights, disease activity index (DAI), shortening of the colon lengths and infiltration of inflammatory cells...
December 6, 2018: International Immunopharmacology
Rafael Oliveira, João Brito, Alexandre Martins, Bruno Mendes, Francisco Calvete, Sandro Carriço, Ricardo Ferraz, Mário Marques
Top European soccer teams that play in UEFA competitions often participate in one, two- or three-games per week. Therefore, it is necessary to understand the variations in training load (TL) according to each team's competitive schedule. The aim of this study was to quantify internal and external TLs within five microcycles: M4 and M5 - one-game weeks; M1 and M3 - two-game weeks; M2 - three-game week). The sample consisted of thirteen elite soccer players. A global positioning system (GPS) was used to measure the total distance covered and distances of different exercise training zones (1-5), the session ratings of perceived exertion (s-RPE) scores and the amount of creatine kinase (CK) created during daily training sessions for the 2015-2016 in-season period...
December 6, 2018: Physiology & Behavior
Kathleen Broderick, Rita Lusk, James Hinderer, Justin Griswold, Rose Boll, Marc Garland, Lawrence Heilbronn, Saed Mirzadeh
In this paper, we describe the 147 Pm production yields and level of impurities from several targets that consisted of milligram quantities of highly enriched 146 Nd oxide irradiated at the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory for durations ranging from 24 to 180 h. A comparison between theoretical and experimental data are also presented, and attempts were made to empirically evaluate the neutron capture cross-sections of 41.3-d 148m Pm and 5.4-d 148g Pm. For a one-cycle irradiation (~24 days), 147 Pm yield reaches a maximum value of 101...
October 31, 2018: Applied Radiation and Isotopes
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