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JOURNAL ARTICLE
Yaseen M Arabi, Hasan M Al-Dorzi, Omar Aldibaasi, Musharaf Sadat, Jesna Jose, Dina Muharib, Haifa Algethamy, Abdulrahman A Al-Fares, Fahad Al-Hameed, Ahmed Mady, Ayman Kharaba, Ali Al Bshabshe, Khalid Maghrabi, Khalid AlGhamdi, Ghulam Rasool, Adnan AlGhamdi, Ghaleb A Almekhlafi, Jamal Chalabi, Haifaa Ibrahim AlHumedi, Maram Hasan Sakkijha, Norah Khalid Alamrey, Amjad Sami Alaskar, Rabeah Hamad Alhutail, Kaouthar Sifaoui, Rakan Alqahtani, Ahmad S Qureshi, Mohammed Moneer Hejazi, Hatim Arishi, Samah AlQahtani, Amro Mohamed Ghazi, Saleh T Baaziz, Abeer Othman Azhar, Sara Fahad Alabbas, Mohammed AlAqeely, Ohoud AlOrabi, Aliaa Al-Mutawa, Maha AlOtaibi, Madiha Fawazy Elghannam, Mohammed Almaani, Sarah Fadel Buabbas, Wadiah Alawi M Alfilfil, Mohammed S Alshahrani, Joel Starkopf, Jean-Charles Preiser, Anders Perner, Jumana Hani AlMubarak, Wafa Mansoor Hazem, Talal Albrahim, Abdulaziz Al-Dawood
BACKGROUND: The optimal amount and timing of protein intake in critically ill patients are unknown. REPLENISH (Replacing Protein via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients) trial evaluates whether supplemental enteral protein added to standard enteral nutrition to achieve a high amount of enteral protein given from ICU day five until ICU discharge or ICU day 90 as compared to no supplemental enteral protein to achieve a moderate amount of enteral protein would reduce all-cause 90-day mortality in adult critically ill mechanically ventilated patients...
May 2, 2024: Trials
#2
JOURNAL ARTICLE
Javier Muñoz Laguna, Astrid Kurmann, Léonie Hofstetter, Emanuela Nyantakyi, Lauren Clack, Heejung Bang, Nadine E Foster, Julia Braun, Milo A Puhan, Mazda Farshad, Cesar A Hincapié
INTRODUCTION: Blinding is a methodologically important aspect in randomised controlled trials yet frequently overlooked in trials of spinal manual therapy interventions for back pain. To help inform the blinding methods of a future, double-placebo-controlled trial comparing spinal manual therapy and nerve root injection for lumbosacral radicular pain, we set four objectives: (1) to assess the feasibility of blinding participants, randomly allocated to an active or placebo-control spinal manual therapy intervention protocol, (2) to assess the feasibility of blinding outcome assessors within the trial, (3) to explore the influence of spinal manual therapy experience and low back pain on blinding, and (4) to explore factors contributing to perceptions about intervention assignment among participants and outcome assessors...
May 2, 2024: Pilot and Feasibility Studies
#3
JOURNAL ARTICLE
Jefferson Antonio Buendía, Diana Guerrero Patiño, Andrés Felipe Zuluaga Salazar
INTRODUCTION: Ventilator-associated pneumonia (VAP) presents a significant challenge in intensive care units (ICUs). Nebulized antibiotics, particularly colistin and tobramycin, are commonly prescribed for VAP patients. However, the appropriateness of using inhaled antibiotics for VAP remains a subject of debate among experts. This study aims to provide updated insights on the efficacy of adjunctive inhaled colistin and tobramycin through a comprehensive systematic review and meta-analysis...
May 2, 2024: BMC Pulmonary Medicine
#4
JOURNAL ARTICLE
Rashida Javed, Kanwal Mahadev, Harsha Gowda
No abstract text is available yet for this article.
May 2, 2024: Archives of Disease in Childhood. Education and Practice Edition
#5
JOURNAL ARTICLE
Stefan Bögli, Marina Sandra Cherchi, Ihsane Olakorede, Andrea Lavinio, Erta Beqiri, Ethan Moyer, Dick Moberg, Peter Smielewski
The Root SedLine Device is used for continuous electroencephalography (cEEG) based sedation monitoring in intensive care patients. The cEEG traces can be collected for further processing and calculation of relevant metrics not already provided. Depending on the device settings during acquisition, the acquired traces may be distorted by max/min values cropping or high digitization error. We aimed to systematically assess the impact of those distortions on metrics used for clinical research in the field of neuromonitoring...
May 2, 2024: Physiological Measurement
#6
JOURNAL ARTICLE
Kartika Palar, Lila A Sheira, Edward A Frongillo, Asher A O'Donnell, Tessa M Nápoles, Mark Ryle, Simon Pitchford, Kim Madsen, Beth Phillips, Elise D Riley, Sheri D Weiser
BACKGROUND: Policy support for "Food is Medicine"-medically tailored meals or groceries to improve health-is rapidly growing. No randomized trials have heretofore investigated the benefits of medically tailored food programs for people living with HIV (PLHIV). METHODS: The CHEFS-HIV pragmatic randomized trial included PLHIV who were clients of Project Open Hand (POH), a San Francisco-based nonprofit food organization. The intervention arm (n = 93) received comprehensive medically tailored meals, groceries, and nutritional education...
May 2, 2024: Journal of Infectious Diseases
#7
JOURNAL ARTICLE
Florian G Scurt, Angela Ernst, Alexandra Korda, Carl-Ludwig Fischer-Fröhlich, Anke Schwarz, Jan U Becker, Christos Chatzikyrkou
BACKGROUND: Kidney biopsies are routinely used for diagnostic and prognostic purposes but their utility in the intensive care unit (ICU) setting is limited. We investigated the associations of clinical and histopathological risk factors with ICU-acute kidney injury (AKI) in donors with brain death (DBD) with kidneys of lower quality and procurement biopsies. METHODS: Overall, 221 donors with brain death, 239 biopsies and 197 recipients were included. The biopsies were reread and scored according to the Banff recommendations...
May 2, 2024: Journal of Nephrology
#8
REVIEW
Maritta Välimäki, Tella Lantta, Raija Kontio
BACKGROUND: Aggressive or violent behaviour is often associated with people with schizophrenia in common perceptions of the disease. Risk assessment methods have been used to identify and evaluate the behaviour of those individuals who are at the greatest risk of perpetrating aggression or violence or characterise the likelihood to commit acts. Although many different interventions have been developed to decrease aggressive or violent incidences in inpatient care, staff working in inpatient settings seek easy-to-use methods to decrease patient aggressive events...
May 2, 2024: Cochrane Database of Systematic Reviews
#9
JOURNAL ARTICLE
Ashleigh E Butler, Tracy A Pasek, Tara-Jane Clark, Elizabeth G Broden
Caring for children and their families at the end-of-life is an essential but challenging aspect of care in the PICU. During and following a child's death, families often report a simultaneous need for protected privacy and ongoing supportive presence from staff. Balancing these seemingly paradoxical needs can be difficult for PICU staff and can often lead to the family feeling intruded upon or abandoned during their end-of-life experience. In this "Pediatric Critical Care Medicine Perspectives" piece, we reframe provision of privacy at the end-of-life in the PICU and describe an essential principle that aims to help the interprofessional PICU team simultaneously meet these two opposing family needs: "Supported Privacy...
May 1, 2024: Pediatric Critical Care Medicine
#10
JOURNAL ARTICLE
Isabela Landsteiner, Jonathan A Pinheiro, Nicole Felix, Douglas Mesadri Gewehr, Rhanderson Cardoso
BACKGROUND: Coronavirus disease 2019 (COVID-19) is associated with hypercoagulability. It remains uncertain whether ongoing anticoagulation for atrial fibrillation (AF) in patients who later contract COVID-19 improves clinical outcomes. OBJECTIVES: To compare chronic oral anticoagulation with no previous anticoagulation in patients with AF who contracted a COVID-19 infection concerning the outcomes of all-cause mortality, COVID-19 mortality, intensive care unit (ICU) admission, and hospitalization...
2024: Arquivos Brasileiros de Cardiologia
#11
REVIEW
Hamza Al Balushi, Junaid Ahmed, Laksh Kumar Ahuja, Fnu Barkha, Mohamed Ishraq Shafeeq, Amna B Baluch, Yahya Altinkaynak, Shenouda Abdallah, Hamza Islam, Rabia Islam, Abdur Rehman, Abdullah Shehryar, Ali Raza
Chronic pancreatitis (CP), an inflammatory disease characterized by irreversible pancreatic changes and progressive fibrosis, significantly impairs patients' quality of life. This systematic review aims to assess the efficacy of antioxidant therapy in enhancing the quality of life of CP patients. Focusing on the role of oxidative stress in CP pathogenesis, we explored several databases for studies evaluating the impact of antioxidant supplementation. The review included randomized controlled trials and cohort studies reporting pain frequency, intensity, and overall quality of life measures...
April 2024: Curēus
#12
REVIEW
Yoshiyasu Ito, Rie Oe, Shota Sakai, Yayoi Fujiwara, Hiroshi Kishimoto
Intensive care unit (ICU) nurses' professional autonomy is a critical factor affecting their ability to sustainably provide high-quality care to patients who are critically ill and to their families. However, in the absence of a systematic or scoping review of ICU nurses' professional autonomy, limited information and evidence are available on this topic. The aim of this scoping review was to clarify the extent and type of evidence on ICU nurses' professional autonomy. This scoping review was conducted in accordance with the Joanna Briggs Institute methodology for scoping reviews...
March 2024: Curēus
#13
JOURNAL ARTICLE
Radha Sharma, Atushi Patel, Tanvi Ojha, Lesley A Pablo, Tina Vosoughi, Carolyn Ziegler, Krishihan Sivapragasam, Andrew D Pinto, David Jenkins, Banafshe Hosseini
BACKGROUND: A significant aspect of the SARS-CoV-2 pathology involves oxidative stress, characterized by an imbalance between the production of harmful free radicals and the body's antioxidant defenses. With the ongoing evolution of SARS-CoV-2, the investigation into non-virus-specific therapeutic options, such as antioxidant therapy, has gained importance. OBJECTIVES: This systematic review and meta-analysis aimed to summarize data from randomized control trials (RCTs) to evaluate the effectiveness and safety of antioxidant therapy in patients with SARS-CoV-2 infection...
May 2024: Current Developments in Nutrition
#14
JOURNAL ARTICLE
Tim Gossye, Dimitri Buytaert, Peter V Smeets, Lieve Morbée, Elke Vereecke, Pieter-Jan Kellens, Eric Achten, Klaus Bacher
BACKGROUND: A physical scatter grid is not often used in pelvic bedside examinations. However, multiple studies regarding scatter correction software (SC SW) are available for mobile chest radiography but the results are unclear for pelvic radiography. PURPOSE: We evaluated SC SW of Fujifilm (Virtual Grid) on gridless pelvic radiographs obtained from a human Thiel-embalmed body to investigate the potential of Virtual Grid in pelvic bedside examinations. METHODS: Gridless, Virtual Grid, and physical grid pelvic radiographs of a female Thiel-embalmed body were collected with a broad range of tube loads...
May 1, 2024: Journal of Applied Clinical Medical Physics
#15
JOURNAL ARTICLE
Jessica Davidson, Yogangi Malhotra, Rebecca Shay, Athis Arunachalam, David Sink, James S Barry, Jeffrey Meyers
The American Academy of Pediatrics (AAP) Standards for Levels of Neonatal Care, published in 2023, highlights key components of a Neonatal Patient Safety and Quality Improvement Program (NPSQIP). A comprehensive Neonatal Intensive Care Unit (NICU) quality and safety infrastructure (QSI) is based on four foundational domains: quality improvement, quality assurance, safety culture, and clinical guidelines. This paper serves as an operational guide for NICU clinical leaders and quality champions to navigate these domains and develop their local QSI to include the AAP NPSQIP standards...
April 23, 2024: Seminars in Perinatology
#16
REVIEW
Cristina Reguera-Carrasco, Sergio Barrientos-Trigo
OBJECTIVE: To establish an evidence-based recommendation on the use of validated scoring systems that measure nursing workload in relation to the complexity of care in adult Intensive Care Units. METHODS: A systematic review based on the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) was conducted (PROSPERO registration: CRD42021251272). We searched for validation studies until July 2023 using the bibliographic databases CINAHL, Scopus, Pubmed, WOS, Cochrane Database, SCIELO, Cuiden and Cuidatge...
April 30, 2024: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
#17
JOURNAL ARTICLE
Yujin Kim, Dong-Hee Kim
The mortality rates among critically ill patients with COVID-19 have been high. The national and institutional infection control policies and resource shortages caused by the pandemic led patients to undergo deaths without dignity and inevitably changed intensive care unit (ICU) end-of-life care (EOLC) practices. This study explores ICU nurses' experiences of providing EOLC for patients with COVID-19 who died. Eight nurses participated in a qualitative phenomenological study. Semi-structured interviews were conducted from July to September 2022...
June 2024: Nursing & Health Sciences
#18
JOURNAL ARTICLE
Nan Lin, Meng Lv, Shujun Li, Yujun Xiang, Jiahuan Li, Hongzhen Xu
OBJECTIVES: To create a nomogram for early delirium detection in pediatric patients following cardiopulmonary bypass. RESEARCH METHODOLOGY/DESIGN: This prospective, observational study was conducted in the Cardiac Intensive Care Unit at a Children's Hospital, enrolling 501 pediatric patients from February 2022 to January 2023. Perioperative data were systematically collected through the hospital information system. Postoperative delirium was assessed using the Cornell Assessment of Pediatric Delirium (CAPD)...
April 30, 2024: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
#19
REVIEW
Jobbe Pl Leenen, Lisette Schoonhoven, Gijs A Patijn
PURPOSE OF REVIEW: Wearable wireless sensors for continuous vital signs monitoring (CVSM) offer the potential for early identification of patient deterioration, especially in low-intensity care settings like general wards. This study aims to review advances in wearable CVSM - with a focus on the general ward - highlighting the technological characteristics of CVSM systems, user perspectives and impact on patient outcomes by exploring recent evidence. RECENT FINDINGS: The accuracy of wearable sensors measuring vital signs exhibits variability, especially notable in ambulatory patients within hospital settings, and standard validation protocols are lacking...
June 1, 2024: Current Opinion in Critical Care
#20
JOURNAL ARTICLE
Jobbe Pl Leenen, Lisette Schoonhoven, Gijs A Patijn
PURPOSE OF REVIEW: Wearable wireless sensors for continuous vital signs monitoring (CVSM) offer the potential for early identification of patient deterioration, especially in low-intensity care settings like general wards. This study aims to review advances in wearable CVSM - with a focus on the general ward - highlighting the technological characteristics of CVSM systems, user perspectives and impact on patient outcomes by exploring recent evidence. RECENT FINDINGS: The accuracy of wearable sensors measuring vital signs exhibits variability, especially notable in ambulatory patients within hospital settings, and standard validation protocols are lacking...
April 8, 2024: Current Opinion in Critical Care
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