keyword
MENU ▼
Read by QxMD icon Read
search

Anal cancer

keyword
https://www.readbyqxmd.com/read/28938543/predictive-clinical-model-of-tumor-response-after-chemoradiation-in-rectal-cancer
#1
Marisa D Santos, Cristina Silva, Anabela Rocha, Carlos Nogueira, Fernando Castro-Poças, António Araujo, Eduarda Matos, Carina Pereira, Rui Medeiros, Carlos Lopes
Survival improvement in rectal cancer treated with neoadjuvant chemoradiotherapy (nCRT) is achieved only if pathological response occurs. Mandard tumor regression grade (TRG) proved to be a valid system to measure nCRT response. The ability to predict tumor response before treatment may significantly have impact the selection of patients for nCRT in rectal cancer. The aim is to identify potential predictive pretreatment factors for Mandard response and build a clinical predictive model design. 167 patients with locally advanced rectal cancer were treated with nCRT and curative surgery...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28935189/early-closure-of-fistula-using-neo-adjuvant-intra-arterial-chemotherapy-in-locally-advanced-anal-cancer
#2
Wulfran Cacheux, Thibaud Koessler, Giacomo Puppa, Eugenio Fernandez, Lisa Ho, Pierre-Yves Dietrich, Thomas Zilli, Abdelkarim Said Allal, Bruno Roche, Frederic Ris, Arnaud Roth
BACKGROUND: Locally advanced anal cancer patients, especially with T4 disease and fistula, have a dismal prognosis. Neo-adjuvant intra-arterial chemotherapy before standard chemoradiation has been shown to be promising in this setting. AIMS: We are reporting results from a larger patient population. METHODS: From 2005 to 2015, 25 consecutive patients with locally advanced anal cancer, 18 of them fistulised, received intra-arterial chemotherapy...
September 5, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28931234/the-evva-cohort-study-anal-and-cervical-type-specific-human-papillomavirus-prevalence-persistence-and-cytologic-findings-in-women-living-with-hiv
#3
Alexandra de Pokomandy, Elaina Kaufman, Christina de Castro, Marie-Hélène Mayrand, Ann N Burchell, Marina Klein, Louise Charest, Manon Auger, Sophie Rodrigues-Coutlée, François Coutlée
Background: The risk of anal cancer due to high-risk human papillomavirus (HR-HPV) is higher in women living with human immunodeficiency virus (HIV) than in the general population. We present findings of cervical and anal HPV and cytologic tests at baseline in the EVVA cohort study and HPV persistence data 6 months after baseline. Methods: Semiannual visits included questionnaires, chart reviews, cervical/anal cytologic and cervical/anal HPV testing for 2 years...
August 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28931221/modeling-of-us-human-papillomavirus-hpv-seroprevalence-by-age-and-sexual-behavior-indicates-an-increasing-trend-of-hpv-infection-following-the-sexual-revolution
#4
Marc D Ryser, Anne Rositch, Patti E Gravitt
Background: The United States has experienced an increase in the incidence of human papillomavirus (HPV)-related cancers that are not screen-detectable. It has been hypothesized, but not directly demonstrated, that this is due to increasing HPV prevalence in the unvaccinated population. Methods: Female self-reported numbers of lifetime sex partners and HPV serology from the National Health and Nutrition Examination Survey (NHANES) were used to develop mathematical models of sexual partner acquisition and antibody dynamics...
September 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28926406/risk-factors-for-anal-hsil-in-hiv-positive-msm-is-targeted-screening-possible
#5
Matthijs L Siegenbeek van Heukelom, Elske Marra, Henry J C de Vries, Maarten F Schim van der Loeff, Jan M Prins
OBJECTIVE: HIV-positive men-who-have-sex-with-men (MSM) are at increased risk for developing anal squamous cell carcinoma (aSCC). Detection of precursor lesions of anal cancer (anal high-grade squamous intraepithelial lesions; HSIL) is cumbersome and expensive. Our objective was to identify potential risk factors for anal HSIL in HIV-positive MSM to develop more stringent screening criteria. DESIGN: We studied a cohort of MSM screened by high-resolution anoscopy (HRA) at three HIV clinics in Amsterdam, the Netherlands...
September 18, 2017: AIDS
https://www.readbyqxmd.com/read/28926109/role-of-viruses-in-gastrointestinal-cancer
#6
REVIEW
Habibollah Mirzaei, Hossein Goudarzi, Gita Eslami, Ebrahim Faghihloo
Gastrointestinal cancers are a global public health problem, which represent a vast majority of all cancer-caused deaths in both men and women. On the other hand, viral pathogens have been long implicated as etiological factors in the onset of certain human cancers, including gastrointestinal tumors. In this regard, Human Papilloma Virus (HPV), Epstein - Barr Virus (EBV) and John Cunningham Virus (JCV) have been more strongly suggested to be involved in gastrointestinal carcinogenesis; so that, the association of HPV with oropharyngeal and anal cancers and also the association of EBV with gastric cancer have been etiologically confirmed by epidemiological and experimental investigations...
September 19, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28924962/the-impact-of-tumour-distance-from-the-anal-verge-on-clinical-management-and-outcomes-in-patients-having-a-curative-resection-for-rectal-cancer
#7
Muhammad Amir Saeed Khan, Chin W Ang, Abdul Rahman Hakeem, Nigel Scott, Rick Nigel Saunders, Ian Botterill
AIM: The clinico-oncological significance of the distance of rectal cancer from the anal verge is unclear and not well reported. The aim of this study is to assess the influence of the rectal cancer distance from the anal verge on clinical management and long-term outcomes after curative resection in a specialised colorectal cancer unit. METHODS: Prospectively collected data on patients who underwent primary rectal cancer treatment at our unit between January 2005 and December 2010 were analysed...
September 18, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28923226/randomized-clinical-trials-in-localized-anal-cancer
#8
REVIEW
Clayton A Smith, Lisa A Kachnic
Management of anal carcinoma began as abdominoperineal resection and has evolved to combined chemotherapy and radiation. Early randomized trials demonstrated superior clinical outcomes of combined modality therapy over radiotherapy alone. Subsequent trials investigated alterations in the standard backbone of radiotherapy concurrent with 5-fluorouracil and mitomycin C with intent to maintain clinical outcomes while reducing treatment-related morbidity. The addition of intensity-modulated radiotherapy to radiation planning and delivery has subsequently reduced acute toxicity and detrimental treatment breaks...
October 2017: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/28918994/meaningful-methods-for-increasing-human-papillomavirus-vaccination-rates-an%C3%A2-integrative-literature-review
#9
Kristin Vollrath, Susan Thul, Jenny Holcombe
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States and is a well-known cause of oropharyngeal, cervical, vaginal, vulvar, penile, and anal cancers. Despite the proven efficacy of the HPV vaccine, vaccination rates remain persistently low. Much literature has focused on attitudes toward the HPV vaccine; however, researchers have also investigated strategies clinicians can use to improve vaccination attitudes and acceptance. Such strategies include provider education, vaccine reminder/recall, and chart audit and feedback...
September 14, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28918425/definitive-chemoradiotherapy-for-anal-carcinoma-long-term-results-based-on-consistent-time-to-event-endpoints
#10
Francesca De Felice, Maria Teresa Martinetti, Simone Orelli, Nadia Bulzonetti, Daniela Musio, Vincenzo Tombolini
AIM: To report the long-term results after definitive chemoradiotherapy (CRT) for anal carcinoma, using consistent time-to-event endpoints. METHODS AND MATERIALS: Anal carcinoma patient charts were reviewed. All patients received definitive CRT. Overall survival (OS), local failure-free survival (LFFS), locoregional failure-free survival (LRFFS), distant metastasis-free survival (DMFS), and anal dysfunction-free survival (ADFS) were estimated. RESULTS: In total, 65 patients were included...
September 16, 2017: Oncology
https://www.readbyqxmd.com/read/28903619/the-volume-of-pet-defined-active-bone-marrow-spared-predicts-acute-hematologic-toxicities-in-anal-cancer-patients-receiving-concurrent-chemoradiotherapy
#11
Christopher Freese, Mickaela Sudhoff, Luke Lewis, Michael Lamba, Jordan Kharofa
No abstract text is available yet for this article.
September 13, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28900991/-transanal-endoscopic-microsurgery-for-treatment-of-rectal-neuroendocrine-tumors
#12
Qianqian Shao, Guole Lin, Huizhong Qiu
OBJECTIVE: To assess the efficacy of full-thickness excision using transanal endoscopic microsurgery (TEM) in the treatment of rectal neuroendocrine tumors (NET). METHODS: Clinicopathological and follow-up data of 90 rectal NET patients who underwent TEM between December 2006 and December 2016 at our department were retrospectively analyzed. TEM was performed as primary excision in 66 patients and as the second complete surgery because of suspected positive margin of samples after colonoscopic polypectomy in 24 patients...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28900786/the-pattern-of-secondary-cancers-in-patients-with-kaposi-sarcoma-in-the-united-states
#13
Vivek Kumar, Mohit Garg, Neha Chaudhary, Parita Soni, Charalampos S Floudas, Chiemeziem Nwanyanwu, Abhinav Chandra
PURPOSE: In the U.S., Kaposi sarcoma (KS) occurs mostly in HIV-infected patients, who are also at increased risk of developing secondary cancers. The trends in secondary cancer risk are unclear in the HAART era. METHODS: We extracted data from the SEER database on patients diagnosed with KS between 1981 and 2013, stratified into the pre-HAART (1981-1995) and HAART (1996-2013) eras. We compared the risk of secondary cancer in KS patients and the general population, and estimated the absolute risk...
September 12, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28899625/cost-effectiveness-of-hpv-vaccination-in-the-context-of-high-cervical-cancer-incidence-and-low-screening-coverage
#14
Triin Võrno, Katrin Lutsar, Anneli Uusküla, Lee Padrik, Terje Raud, Rainer Reile, Oliver Nahkur, Raul-Allan Kiivet
BACKGROUND: Estonia has high cervical cancer incidence and low screening coverage. We modelled the impact of population-based bivalent, quadrivalent or nonavalent HPV vaccination alongside cervical cancer screening. METHODS: A Markov cohort model of the natural history of HPV infection was used to assess the cost-effectiveness of vaccinating a cohort of 12-year-old girls with bivalent, quadrivalent or nonavalent vaccine in two doses in a national, school-based vaccination programme...
September 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28898333/-usefulness-of-imaging-studies-in-prostate-cancer-analysis-of-241-patients
#15
Nagel Martínez M, Carlos Calvo, Álvaro Ibarra, Christian Ramos, Norman Zambrano
BACKGROUND: The role of staging studies in patients with prostate cancer (PCa) is a topic of discussion. AIM: To evaluate the usefulness of imaging studies in patients with prostate cancer. MATERIAL AND METHODS: We reviewed the pathology service records to identify patients with prostate cancer diagnosed between 2003 and 2013. We reviewed the electronic medical records of those patients identified as having a prostate cancer. Patients were grouped according D’amico’s classification of cancer dissemination risk...
May 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28891852/condyloma-acuminatum-anal-intraepithelial-neoplasia-and-anal-cancer-in-the-setting-of-hiv-do-we-really-understand-the-risk
#16
Edward A Fazendin, Alexander J Crean, Jessica M Fazendin, Robert J Kucejko, Harkenwar S Gill, Juan L Poggio, David E Stein
BACKGROUND: The gold standard for surveillance of patients with anal lesions is unclear. OBJECTIVE: The aim of this study was to stratify patients for risk of progression of disease and to determine appropriate intervals for surveillance of patients with anal disease. DESIGN: This was a retrospective chart review for patients treated for anal lesions between 2007 and 2014. Only patients with ≥1 year of follow-up from index evaluation, pathology, documented physical examination, and anoscopy findings were included for analysis...
October 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28891266/analysis-of-outcomes-achieved-with-squamous-cell-carcinomas-of-the-anus-in-a-single-university-hospital-over-the-last-two-decades-clinical-response-rate-relapse-and-survival-of-190-patients
#17
Gianpiero Gravante, James Andrew Stephenson, Mohamed Elshaer, Ahmed Osman, Subramaniam Vasanthan, Joseph H Mullineux, Mohamed Akil Dilawar Gani, David Sharpe, Justin Yeung, Michael Norwood, Andrew Miller, Kirsten Boyle, David Hemingway
BACKGROUND AND OBJECTIVES: We reviewed our series of anal squamous cell carcinomas (ASCC) treated over the last two decades. METHODS: ASCC patients undergoing treatment at the Leicester Royal Infirmary between 1998 and 2016 were selected. Age, gender, pathological tumor characteristics, treatment adopted, the overall survival (OS), cancer-specific survival (CSS), and disease-free survival (DFS) at 5-year follow-up were recorded and calculated. RESULTS: A total of 190 ASCC were reviewed, of these 64...
September 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28884454/prevalence-of-patient-reported-gastrointestinal-symptoms-and-agreement-with-clinician-toxicity-assessments-in-radiation-therapy-for-anal-cancer
#18
Ashlyn Tom, Antonia V Bennett, Diana Rothenstein, Ethel Law, Karyn A Goodman
PURPOSE: Gastrointestinal (GI) symptoms pose a significant burden to patients receiving chemoradiation therapy (CRT) for anal cancer; however, the impact of symptoms from the patient perspective has not been quantified. This retrospective study examined and compared patient and clinician reports of acute GI toxicity during CRT. MATERIALS AND METHODS: Patients treated with definitive RT using intensity-modulated radiation therapy for anal cancer between 9/09 and 11/12 were reviewed...
September 7, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28883706/simple-instruments-facilitating-achievement-of-transanal-total-mesorectal-excision-in-male-patients
#19
Chang Xu, Hua-Yu Song, Shao-Liang Han, Shi-Chang Ni, Hu-Xiang Zhang, Chun-Gen Xing
AIM: To assess the efficacy of a modified approach with transanal total mesorectal excision (taTME) using simple customized instruments in male patients with low rectal cancer. METHODS: A total of 115 male patients with low rectal cancer from December 2006 to August 2015 were retrospectively studied. All patients had a bulky tumor (tumor diameter ≥ 40 mm). Forty-one patients (group A) underwent a classical approach of transabdominal total mesorectal excision (TME) and transanal intersphincteric resection (ISR), and the other 74 patients (group B) underwent a modified approach with transabdominal TME, transanal ISR, and taTME...
August 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28882511/-doses-to-organs-at-risk-for-conformational-and-stereotactic-radiotherapy-bladder
#20
L Duvergé, J Castelli, T Lizée, R de Crevoisier, D Azria
Bladder dose constraints in case of conformational radiotherapy/intensity-modulated radiotherapy and stereotactic radiotherapy are reported from the literature, in particular from the French radiotherapy society RECORAD recommendations, according to the treated pelvic tumor sites. The dose-volume effect on urinary toxicity is not clearly demonstrated, making difficult to establish absolute dose constraints for the bladder. In case of high-dose prostate cancer radiotherapy, the bladder dose constraints are: V60Gy<50% and maximum dose<80Gy for standard fractionation and V60Gy<5%, V48Gy<25% and V41Gy<50% for moderate hypofractionation (20 fractions of 3Gy)...
September 4, 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
keyword
keyword
1629
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"