Read by QxMD icon Read


Shih-Yi Sheu, Cheng-Wen Huang, Jhen-Ci Chen, Zih-Han Chen, Wen-Ming Chen
A bacterial strain, designated Jyi-02T , was isolated from a flooded rice field in Taiwan and characterized using the polyphasic taxonomy approach. Cells of strain Jyi-02T were aerobic, Gram-stain-negative, rod-shaped, non-motile and formed yellowish orange coloured colonies. Growth occurred at 10-40 °C (optimum, 20 °C) and pH 5.0-9.0 (optimum, pH 7.0) and in the presence of 0-1.0 % NaCl (optimum, 0 %, w/v). The major fatty acids (>10 %) of strain Jyi-02T were C18 : 1ω7c, summed feature 3 (C16 : 1ω7c and/or C16 : 1ω6c) and C14 : 0 2-OH...
May 18, 2018: International Journal of Systematic and Evolutionary Microbiology
Fan Liu, Jin Tu, Xiaorui Wang, Jiaqiang Wang, Yanbing Gong, Mengmeng Han, Xianxi Dang, Qiuyan Liao, Qian Peng, Qianqian Li, Zhen Li
Two isomers of mm-TPE(PI)2 and pp-TPE(PI)2, constructed by the two same aromatic blocks of tetraphenylethene and phenanthro[9,10-d]imidazole, exhibit totally different mechanoluminescence, as a result of the ignorable different linkage positions on the tetraphenylethene moiety. Detailed analysis and theoretical calculations demonstrate the structure-packing-property relationship of organic mechanoluminescent luminogens, with the emphasis on the important role of molecular packing in the solid state.
May 16, 2018: Chemical Communications: Chem Comm
Zhiwei Chu, Zhuxin Fan, Xiang Zhang, Xiaofeng Tan, Dongxu Li, Guohua Chen, Qinghua Zhao
An aggregation-caused quenching (ACQ)-active polymer (PF), an aggregation-induced emission (AIE)-active polymer (PFTPE) and an aggregation-enhanced emission (AEE)-active polymer (PTTPE) were synthesized by tetraphenylethane (TPE), fluorene and thiophene moieties. Polyurethane (PU) foams modified by PF, PFTPE and PTTPE, namely PU-PF, PU-PFTPE and PU-PTTPE, using ultrasonication-assisted method have been prepared. A comparative study of PU-PF, PU-PFTPE and PU-PTTPE for detection explosives had been performed, and significant fluorescence quenching was observed with the introduction of PA solutions...
May 15, 2018: Sensors
Maude Desroches, Jean-François Morin
Seven π-extended derivatives of the known tetraphenylethylene (TPE) have been studied for their aggregation-induced emission properties. Modulation of the emission properties of these anthanthrone-based luminogens has been accomplished through simple chemical modifications on four different positions of the anthanthrone core. The optical properties, along with X-ray diffraction and DFT-optimized structures, were studied. This work provides a new, easily accessible bridging unit for the TPE framework with a red-shifted emission...
May 10, 2018: Organic Letters
Enbo Yang, Joy Li, Michael Cho, Shu Xiao
Ultrashort electric pulses (ns-ps) are useful in gaining understanding as to how pulsed electric fields act upon biological cells, but the electric field intensity to induce biological responses is typically higher than longer pulses and therefore a high voltage ultrashort pulse generator is required. To deliver 1 ns pulses with sufficient electric field but at a relatively low voltage, we used a glass-encapsulated tungsten wire triple-point electrode (TPE) at the interface among glass, tungsten wire, and water when it is immersed in water...
2018: BioMed Research International
Philipp Y Maximov, Balkees Abderrahman, Sean W Fanning, Surojeet Sengupta, Ping Fan, Ramona F Curpan, Daniela Maria Quintana Rincon, Jeffery A Greenland, Shyamala S Rajan, Geoffrey L Greene, V Craig Jordan
Estrogen therapy was used to treat advanced breast cancer in postmenopausal women for decades until the introduction of tamoxifen. Resistance to long-term estrogen deprivation (LTED) with tamoxifen and aromatase inhibitors used as a treatment for breast cancer inevitably occurs, but unexpectedly low dose estrogen can cause regression of breast cancer and increase disease free survival in some patients. This therapeutic effect is attributed to estrogen-induced apoptosis in LTED breast cancer. Here we describe modulation of the estrogen receptor liganded with antiestrogens (endoxifen, 4-hydroxytamoxifen) and an estrogenic triphenylethylene (TPE) EthoxyTPE (EtOXTPE) on estrogen-induced apoptosis in LTED breast cancer cells...
May 8, 2018: Molecular Pharmacology
Weihua Zhuang, Yangyang Xu, Gaocan Li, Jun Hu, Boxuan Ma, Tao Yu, Xin Su, Yunbing Wang
Intelligent polymeric micelles for tumor targeting antitumor drug delivery and bioimaging have drawn a broad attention due to the reduced systemic toxicity, enhanced efficacy of drugs and potential application of tumor diagnosis. Herein, we developed a multifunctional polymeric micelle system based on pH and redox dual responsive mPEG-P (TPE- co-AEMA) copolymer for stimuli triggered drug release and aggregation-induced emission (AIE) active imaging. These mPEG-P (TPE- co-AEMA) based micelles showed excellent biocompatibility and emission property, exhibiting great potential application for cellular imaging...
May 8, 2018: ACS Applied Materials & Interfaces
Xuedan Liu, Aisen Li, Weiqing Xu, Zhiyong Ma, Xinru Jia
We herein report a newly synthesized simple molecule, named TPE[double bond, length as m-dash]C4, with twisted D-A structure. TPE[double bond, length as m-dash]C4 showed two intrinsic emission bands ascribed to the locally excited (LE) state and the intramolecular charge transfer (ICT) state, respectively. In the crystal state, the LE emission band is usually observed. However, by applying hydrostatic pressure to the powder sample and the single crystal sample of TPE[double bond, length as m-dash]C4, dual-fluorescence (445 nm and 532 nm) was emerged under high pressure, owing to the pressure-induced emission band separation of the hybridized local and charge transfer excited state (HLCT)...
May 8, 2018: Physical Chemistry Chemical Physics: PCCP
Shun-Wen Cheng, Ting Han, Teng-Yung Huang, Yu-Hsin Chang Chien, Cheng-Liang Liu, Ben Zhong Tang, Guey-Sheng Liou
A novel aggregation enhanced emission (AEE)-active polyamide TPA-CN-TPE with a high photoluminesence characteristic was successfully synthesized by the direct polymerization of 4-cyanotriphenyl diamine (TPA-CN) and tetraphenylethene (TPE)-containing dicarboxylic acid. The obtained luminescent polyamide plays a significant role as the polymer electret layer in organic field-effect transistors (OFET)-type memory. The strong green emission of TPA-CN-TPE under ultraviolet (UV) irradiation can be directly absorbed by the pentacene channel, displaying a light-induced programming and voltage-driven erasing organic phototransistor-based non-volatile memory...
May 7, 2018: ACS Applied Materials & Interfaces
Jun Hu, Weihua Zhuang, Boxuan Ma, Xin Su, Tao Yu, Gaocan Li, Yanfei Hu, Yunbing Wang
Intelligent polymeric micelles have been developed as potential nanoplatforms for efficient drug delivery and diagnosis. Herein, we successfully prepared redox-sensitive polymeric micelles combined aggregation induced emission (AIE) imaging as an outstanding anticancer drug carrier system for simultaneous chemotherapy and bioimaging. The amphiphilic copolymer TPE-SS-PLAsp-b-PMPC could self-assemble into spherical micelles and these biomimetic micelles exhibited great biocompatibility and remarkable ability in anti-protein adsorption, showing great potential for biomedical application...
May 2, 2018: Bioconjugate Chemistry
Hye-Mee Kwon, In-Gu Jun, JungBok Lee, Young-Jin Moon, Kyeo-Woon Jung, Hye-Won Jeong, Yong-Seok Park, Jun-Gol Song, Gyu-Sam Hwang
Desensitisation with therapeutic plasma exchange (TPE) is essential for ABO-incompatible (ABO-I) liver transplants (LTs). However, excessive citrate load and coagulation disturbances after TPE have been poorly studied, in particular in cirrhotic patients with hypocapnic alkalosis, metabolic compensation and electrolyte imbalances. We retrospectively evaluated 1123 consecutive LT recipients (923 ABO-compatible [ABO-C], 200 ABO-I) from November 2008 to May 2015. TPE was generally performed a day before LT and blood sampling was performed before anaesthesia induction...
April 27, 2018: Scientific Reports
Jing Guan, Jianmin Li, Yang Wang, Zhiguang Liu, Xiaoping Long, Chanyuan Pan
To evaluate the clinical value of surfactant protein-A (SP-A) in exudate pleural effusion (EPE).
 Methods: This clinical study was prospective, observational and cross-sectional. Two hundred and fifteen patients with pleural effusion were divided into the transudate pleural effusions (TPE) group and the EPE group. TPE patients served as the control group. The concentrations of pleural effusions SP-A (SP-Apl) and serum SP-A (SP-Ase) were measured by ELISA, and receiver operator characteristic (ROC) curve and multivarate Cox analysis of SP-A was analysed for its clinical value...
March 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Sandip Biswas, Debabrata Jana, Gundam Sandeep Kumar, Subrata Maji, Pronab Kundu, Uttam Kumar Ghorai, Rajendra P Giri, Bidisa Das, Nitin Chattopadhyay, Binay K Ghorai, Somobrata Acharya
Luminescent materials containing both the mechanoluminescence and electroluminescence properties are the quest for sensing and optoelectronic applications. We report on the synthesis of a new tailor-made luminogen, 1,2-bis(4-(1-([1,1'-biphenyl]-4-yl)-2,2-diphenylvinyl)phenyl)-1,2-diphenylethene (TPE 5) using Suzuki coupling reaction with high yield. Aggregation induced emission (AIE) active complex TPE 5 forms supramolecular spherical aggregates at the air-water interface of a Langmuir trough. As a consequence, a large enhancement of luminescence is obtained from the mono and multilayer Langmuir Blodgett films of TPE 5 owing to the AIE effect...
April 26, 2018: ACS Applied Materials & Interfaces
Harleen Dehal, Michael Adashek
Objective: To emphasize the role of apheresis in management of pancreatitis. Methods: The clinical course of a patient admitted for hypertriglyceridemia-induced pancreatitis (HTGP) complicated by multiorgan dysfunction is described, who demonstrated dramatic improvement in his clinical status after total plasma exchange (TPE). In addition, the current guidelines for TPE and the alternative treatment options for HTGP are also presented. Results: A patient presenting with pancreatitis associated with severe systemic inflammatory response was admitted to our hospital with an initial triglyceride level of 1181 mg/dL...
2018: Case Reports in Medicine
Mizuho Nishio, Mitsuo Nishizawa, Osamu Sugiyama, Ryosuke Kojima, Masahiro Yakami, Tomohiro Kuroda, Kaori Togashi
We aimed to evaluate a computer-aided diagnosis (CADx) system for lung nodule classification focussing on (i) usefulness of the conventional CADx system (hand-crafted imaging feature + machine learning algorithm), (ii) comparison between support vector machine (SVM) and gradient tree boosting (XGBoost) as machine learning algorithms, and (iii) effectiveness of parameter optimization using Bayesian optimization and random search. Data on 99 lung nodules (62 lung cancers and 37 benign lung nodules) were included from public databases of CT images...
2018: PloS One
Ningwei Sun, Kaixin Su, Ziwei Zhou, Ye Yu, Xuzhou Tian, Daming Wang, Xiaogang Zhao, Hongwei Zhou, Chunhai Chen
Electrofluorochromism has attracted great attention due to the intelligence optoelectronic and sensing applications. The intrinsically switchable fluorophores with high solid-state fluorescence are regarded as key for ideal electrofluorochromic materials. Here, we reported an AIE-active polyamide with diphenylamine and tetraphenylethlene units, showing high fluorescence quantum yield up to 69.1% for the solid polymer film and stable electrochemical cycling stability. The polyamide exhibited reversible color and emission switching even in hundreds of cycles, and the fluorescence on/off contrast ratio was determined up to 417, which is the highest value to our knowledge...
April 19, 2018: ACS Applied Materials & Interfaces
Neng Yan, Sheng Xie, Ben Zhong Tang, Wen-Xiong Wang
We employed a fluorogenic Ag+ sensor, tetrazole-functionalized tetraphenylethylene derivative 1 (TEZ-TPE-1), to investigate the dissolution kinetics of AgNPs and AgNWs in aquatic environments. Real-time and quantitative monitoring of Ag+ release was achieved by using the proposed method, which agreed well with the conventional ICP-MS detection method.
April 18, 2018: Chemical Communications: Chem Comm
Yanxia Chen, Xuehong Min, Xiqi Zhang, Feilong Zhang, Simeng Lu, Li-Ping Xu, Xiaoding Lou, Fan Xia, Xueji Zhang, Shutao Wang
Superwettable microchips with superhydrophilic microwells on superhydrophobic substrate have attracted increasing attention in fluorescence-based biological and medical diagnostics. However, traditional fluorophores often suffer from the aggregation-caused quenching (ACQ) problem at high concentration or in aggregated state. Here, we developed an AIE-based superwettable microchip by combining the evaporation-induced enrichment of superwettable microchips and the aggregation-induced emission of AIEgens together into one chip...
April 7, 2018: Biosensors & Bioelectronics
Aynur Soyuöz, Ömer Karadağ, Tülay Karaağaç, Levent Kılıç, Şule Apraş Bilgen, Osman İlhami Özcebe
Objective: Therapeutic plasma exchange (TPE) offers an alternative therapeutic modality for patients with systemic lupus erythematosus (SLE) and primary antiphospholipid syndrome (APS). However, there is conflicting evidence regarding its efficacy in different sub-phenotypes. This study aimed to investigate the main clinical characteristics and outcomes of patients with different phenotypes of SLE and APS treated with TPE at a tertiary care center. Methods: The database of the Blood and Apheresis Unit between 2001 and 2013 was screened for patients with SLE and primary APS...
March 2018: European Journal of Rheumatology
Sascha Knauf, Simone Lüert, David Šmajs, Michal Strouhal, Idrissa S Chuma, Sieghard Frischmann, Mohammed Bakheit
We show proof of concept for gene targets (polA, tprL, and TP_0619) that can be used in loop-mediated isothermal amplification (LAMP) assays to rapidly differentiate infection with any of the three Treponema pallidum subspecies (pallidum (TPA), pertenue (TPE), and endemicum (TEN)) and which are known to infect humans and nonhuman primates (NHPs). Four TPA, six human, and two NHP TPE strains, as well as two human TEN strains were used to establish and validate the LAMP assays. All three LAMP assays were highly specific for the target DNA...
April 12, 2018: PLoS Neglected Tropical Diseases
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"