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Stroke sleep

Matías Otto-Yáñez, Rodrigo Torres-Castro, Joaquín Nieto-Pino, Mercedes Mayos
Stroke, one of the main causes of disability and death worldwide, is frequently associated to the obstructive sleep apnea-hypopnea syndrome. This sleep disorder has been demonstrated to be an independent risk factor for stroke, and therefore its investigation and treatment has been recommended for patients with stroke. Mechanisms relating these two clinical disorders include: oxidative stress, cerebral blood flow alterations, autonomic dysfunction, and hypercoagulability, as well as patent foramen ovale, blood pressure, and heart rhythm disorders...
2018: Medicina
Sira Thiel, Franziska Lettau, Protazy Rejmer, Cristina Rossi, Sarah R Haile, Esther I Schwarz, Anna S Stöberl, Noriane A Sievi, Andreas Boss, Anton S Becker, Sebastian Winklhofer, John R Stradling, Malcolm Kohler
Introduction: Impaired cerebral vascular reactivity (CVR) increases long-term stroke risk. Obstructive sleep apnoea (OSA) is associated with peripheral vascular dysfunction and vascular events. The aim of this trial was to evaluate the effect of continuous positive airway pressure (CPAP) withdrawal on CVR. Methods: 41 OSA patients (88% male, mean age 57±10 yrs.) were randomised to subtherapeutic, or continuation of therapeutic, CPAP. At baseline, and after two weeks, patients underwent a sleep study and magnetic resonance imaging (MRI)...
November 28, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Hayato Tada, Masa-Aki Kawashiri, Kenji Yasuda, Masakazu Yamagishi
OBJECTIVE: We aimed to investigate the association between questionnaires related to lifestyle habits and atherosclerotic cardiovascular diseases (ASCVD). DESIGN: Cross-sectional observational study. SETTINGS: Community-based medical checkups, called specific health checkups started in Japan since 2008. This checkup includes standard medical examinations as well as a specific questionnaire related to lifestyle habits. PARTICIPANTS: Overall, 47,842 subjects (males = 16,913, 35...
2018: PloS One
Devin L Brown, Xiaqing Jiang, Chengwei Li, Erin Case, Cemal B Sozener, Ronald D Chervin, Lynda D Lisabeth
OBJECTIVE/BACKGROUND: To assess (1) pre and post-stroke screening for sleep apnea (SA) within a population-based study without an academic medical center, and (2) ethnic differences in post-stroke sleep apnea screening among Mexican Americans (MAs) and non-Hispanic whites (NHWs). PATIENTS/METHODS: MAs and NHWs with stroke in the Brain Attack Surveillance in Corpus Christi project (2011-2015) were interviewed shortly after stroke about the pre-stroke period, and again at approximately 90 days after stroke in reference to the post-stroke period...
September 27, 2018: Sleep Medicine
J Howard Jaster, Josef Zamecnik, Aldo Bruno Giannì, Giulia Ottaviani
INTRODUCTION: In 2015, a multinational randomized controlled phase IV clinical trial of adaptive servoventilation for the management of heart failure with central sleep apnea was halted in progress because more patients in the study group were dying than in the control group. One year later, another large clinical trial reported results on the effectiveness of continuous positive airway pressure (CPAP) in preventing sudden death and other cardiovascular events such as heart attack and stroke in patients with preexisting vascular disease as well as obstructive sleep apnea...
October 26, 2018: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
Houzhen Tuo, Zelong Tian, Xiaoyang Ma, Yinong Cui, Yun Xue, Jingjing Che, Chunling Xu, Kui Chen, Yongbo Zhang, Liyan Zhang, Hongyan Bi, Weidong Le, William Ondo
BACKGROUND: Recent studies have suggested that cerebral ischemic infarction may contribute to the development of restless legs syndrome (RLS). This study analyzed the clinical and radiological profiles of RLS with onset after acute lacunar infarction. METHODS: In this retrospective study we enrolled 244 consecutive patients with acute lacunar infarction between January 2012 and June 2014. RLS was identified and evaluated based on the International RLS Rating Scale (IRLS-RS)...
June 26, 2018: Sleep Medicine
Tomohiko Shiina, Keisuke Suzuki, Madoka Okamura, Takeo Matsubara, Koichi Hirata
BACKGROUND: The clinical-radiological correlation between restless legs syndrome (RLS) or its variants and acute ischemic stroke remains unclear. METHODS: This study prospectively included 104 consecutive patients with acute ischemic stroke, confirmed by diffusion-weighted imaging. The frequency and clinical characteristics of RLS or RLS variants were evaluated according to the International RLS Study Group criteria, as was the topography of the associated lesions...
November 18, 2018: Acta Neurologica Scandinavica
Xilin Li, Ahmed Al-Ani, Sai Ho Ling
Patients with sleep apnea (SA) are at increased risk of stroke and cardiovascular disease. Diagnosis of sleep apnea depends on the standard overnight polysomnography (PSG). In this study, the DREAM Apnea Database was used to evaluate the importance of the various features proposed in the literature for the analysis of sleep apnea. Various timeand frequency- domain features that include wavelet and power spectral density were extracted from ECG, EMG, EEG, airflow, SaO2, abdominal and thoracic recordings. Evaluation measures of one-way analysis of variance (ANOVA) and Rank-Sum test were used to test the performance of different features...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
J Słomko, M Zawadka-Kunikowska, J J Klawe, M Tafil-Klawe, J Newton, P Zalewski
In this study we set out to understand is sleep fragmentation affects the cardiovascular regulation and circadian variability of core body temperature more or less than sleep deprivation. 50 healthy men (age 29.0+/-3.1 years; BMI 24.3+/-2.1 kg/m(2)) participated in a 3-day study that included one adaptative night and one experimental night involving randomization to: sleep deprivation (SD) and sleep fragmentation (SF). The evaluation included hemodynamic parameters, measures of the spectral analysis of heart rate and blood pressure variability, and the sensitivity of arterial baroreflex function...
November 14, 2018: Physiological Research
Clare L Fraser
PURPOSE OF REVIEW: Obstructive sleep apnea (OSA) is increasing in prevalence. The intermittent hypoxia of OSA has wide-ranging effects on a patient's general health outcomes. However, gold-standard investigations and treatment are expensive and a significant burden on patients. Therefore, OSA research remains focused on improving the means of diagnosing and treating OSA, in high-risk-associated conditions. This review is to provide an update on the advances in the field of OSA. RECENT FINDINGS: There has been recent debate about the best practice for diagnosis and treatment of OSA...
November 9, 2018: Current Opinion in Neurology
Xue Li, Xiuyu Pang, Zhipeng Liu, Qiao Zhang, Changhao Sun, Jianjun Yang, Ying Li
BACKGROUND: The joint effect of daytime naps and night sleep on the risk of stroke has not been clarified. Our research aimed to verify this relationship based on data from a large sample-sized cross-sectional study and a cohort study. METHODS: The cross-sectional study included 7887 subjects, aged 20-74 years. Using stratified random sampling, 1928 individuals were selected for the cohort study. We then followed up with these individuals for an average of 4.94 years and collected detailed sleep information with the Pittsburgh Sleep Quality Index (PSQI)...
May 24, 2018: Sleep Medicine
HyunSoo Oh, JinA Mo, Whasook Seo
AIM: To review and identify correlates of cognitive impairment in chronic kidney failure patients on hemodialysis. BACKGROUND: The literature is consistent regarding the high prevalence of cognitive impairment among chronic kidney failure patients on hemodialysis and its dependence on multidimensional risk factors. DESIGN: Systematic review and meta-analysis based on Cochrane Handbook and PRISMA. DATA SOURCES: Electronic searches of the MEDLINE, EMBASE, Cochrane Library databases and major Korean databases were used...
November 8, 2018: Journal of Advanced Nursing
Emily R Rosario, Stephanie E Kaplan, Sepehr Khonsari, Garrett Vazquez, Niyant Solanki, Melanie Lane, Hiriam Brownell, Sheila S Rosenberg
Background: While research suggests a benefit of hyperbaric oxygen therapy (HBOT) for neurologic injury, controlled clinical trials have not been able to clearly define the benefits. Objective: To investigate the effects of HBOT on physical and cognitive impairments resulting from an ischemic stroke. Methods: Using a within-subject design a baseline for current functional abilities was established over a 3-month period for all subjects (n=7)...
2018: Neurology Research International
Irene L Katzan, Andrew Schuster, Christopher Newey, Ken Uchino, Brittany Lapin
OBJECTIVES: To compare the degrees to which 8 domains of health are affected across types of cerebrovascular events and to identify factors associated with domain scores in different event types. METHODS: This was an observational cohort study of 2,181 patients with ischemic stroke, intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), or TIA in a cerebrovascular clinic from February 17, 2015, to June 2, 2017 who completed Quality of Life in Neurologic Disorders executive function and the following Patient-Reported Outcomes Measurement Information System scales as part of routine care: physical function, satisfaction with social roles, fatigue, anxiety, depression, pain interference, and sleep disturbance...
October 31, 2018: Neurology
Matthew P Pase
No abstract text is available yet for this article.
October 30, 2018: Neurology
Tetyana Kendzerska, Richard S Leung, Shawn D Aaron, Najib Ayas, Jacqueline S Sandoz, Andrea S Gershon
RATIONALE: The combined impact of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) on cardiovascular outcomes remains controversial. OBJECTIVES: We determined whether the combined presence of COPD and severe obstructive sleep apnea (OSA) defined by the apnea-hypopnea index (AHI) or degree of nocturnal hypoxemia is associated with increased hazard of cardiovascular events and mortality. METHODS: Prospectively collected data from adults with suspected OSA who underwent sleep study between 1994 and 2010 were linked to provincial administrative data-to determine a presence of COPD and composite outcome...
October 29, 2018: Annals of the American Thoracic Society
Chun Shing Kwok, Evangelos Kontopantelis, George Kuligowski, Matthew Gray, Alan Muhyaldeen, Christopher P Gale, George M Peat, Jacqueline Cleator, Carolyn Chew-Graham, Yoon Kong Loke, Mamas Andreas Mamas
Background There is growing evidence that sleep duration and quality may be associated with cardiovascular harm and mortality. Methods and Results We conducted a systematic review, meta-analysis, and spline analysis of prospective cohort studies that evaluate the association between sleep duration and quality and cardiovascular outcomes. We searched MEDLINE and EMBASE for these studies and extracted data from identified studies. We utilized linear and nonlinear dose-response meta-analysis models and used DerSimonian-Laird random-effects meta-analysis models of risk ratios, with inverse variance weighting, and the I2 statistic to quantify heterogeneity...
August 7, 2018: Journal of the American Heart Association
Mari Takala, Juha Puustinen, Esa Rauhala, Anu Holm
OBJECTIVES: Sleep-Disordered Breathing (SDB) is frequent in stroke patients. Polysomnography (PSG) and cardiorespiratory polygraphy are used to confirm SDB, but the need for PSG exceeds the available resources for systematic testing. Therefore, a simple and robust pre-screening instrument is necessary to identify the patients with an urgent need for a targeted PSG. The aim of this systematic review was to identify and evaluate the available methods to pre-screen stroke patients possibly suffering from SDB...
October 29, 2018: Brain and Behavior
John T Schousboe, Allyson M Kats, Lisa Langsetmo, Tien N Vo, Brent C Taylor, Ann V Schwartz, Peggy M Cawthon, Cora E Lewis, Elizabeth Barrett-Connor, Andrew R Hoffman, Eric S Orwoll, Kristine E Ensrud
Background Visceral adipose tissue ( VAT ) and other measures of central obesity predict incident atherosclerotic cardiovascular disease ( ASCVD ) events in middle-aged individuals, but these associations are less certain in older individuals age 70 years and older. Our objective was to estimate the associations of VAT and the android-gynoid fat mass ratio, another measure of central obesity, with incident ASCVD events among a large cohort of older men. Methods and Results Two thousand eight hundred ninety-nine men (mean [ SD ] age 76...
August 21, 2018: Journal of the American Heart Association
Dawn M Bravata, Jason Sico, Carlos A Vaz Fragoso, Edward J Miech, Marianne S Matthias, Rachel Lampert, Linda S Williams, John Concato, Cristina S Ivan, J D Fleck, Lauren Tobias, Charles Austin, Jared Ferguson, Radu Radulescu, Lynne Iannone, Susan Ofner, Stanley Taylor, Li Qin, Christine Won, H Klar Yaggi
Background Obstructive sleep apnea ( OSA ) is common among patients with acute ischemic stroke and transient ischemic attack. We evaluated whether continuous positive airway pressure for OSA among patients with recent ischemic stroke or transient ischemic attack improved clinical outcomes. Methods and Results This randomized controlled trial among patients with ischemic stroke/transient ischemic attack compared 2 strategies (standard or enhanced) for the diagnosis and treatment of OSA versus usual care over 1 year...
August 21, 2018: Journal of the American Heart Association
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