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Nephrolithiasis transplant donor

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https://www.readbyqxmd.com/read/29553430/the-radiological-evaluation-process-of-the-potential-live-kidney-donor-assessment-programme-at-al-shifa-hospital-study-and-clinical-audit
#1
Musallam Abukhalil, Osama Mehjez, Mohammed Aladdam, Bettina Bottcher, Sobhi Skaik, Mohammed Matter
BACKGROUND: In 2013, al-Shifa Hospital, the largest hospital in the Gaza Strip, introduced an assessment programme for potential kidney donors on the basis of medical and radiological evaluation. The aims of this study and an associated clinical audit were to examine the final outcome of the potential live kidney donors assessment programme, to review the findings and determine the level of accuracy of the radiological evaluations, to assess the completeness and standard of radiological record keeping, and to evaluate adherence to guidelines...
February 21, 2018: Lancet
https://www.readbyqxmd.com/read/29536032/a-successful-approach-to-kidney-transplantation-in-patients-with-enteric-secondary-hyperoxaluria
#2
Joke I Roodnat, Anneke M E de Mik-van Egmond, Wesley J Visser, Stefan P Berger, Wilbert A G van der Meijden, Felix Knauf, Madelon van Agteren, Michiel G H Betjes, Ewout J Hoorn
Background: Enteric hyperoxaluria due to malabsorption may cause chronic oxalate nephropathy and lead to end-stage renal disease. Kidney transplantation is challenging given the risk of recurrent calcium-oxalate deposition and nephrolithiasis. Methods: We established a protocol to reduce plasma oxalic acid levels peritransplantation based on reduced intake and increased removal of oxalate. The outcomes of 10 kidney transplantation patients using this protocol are reported...
December 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28579066/renal-transplantation-using-stone-bearing-deceased-donor-kidneys-experience-of-a-transplant-center-in-china
#3
Chuan-Bao Chen, Liang Zhao, Ming Han, Xiao-Ping Wang, Jian Zhou, Xiao-Peng Yuan, Chang-Xi Wang
OBJECTIVE: To evaluate the outcomes of transplantation of deceased donor stone-bearing kidneys. METHODS: A total of 32 patients who received renal transplantation at our center from July 2011 to June 2016 were included. Eight recipients received kidneys with incidental renal stone(s) (stone group). Twenty-four recipients received kidneys without renal stones (non-stone group). The transplantation outcomes of the 2 groups were compared. RESULTS: There was 1 case of postoperative urinary tract infection in the stone group, and 2 cases in the non-stone group...
September 2017: Urology
https://www.readbyqxmd.com/read/27800047/expanding-living-kidney-donor-criteria-with-ex-vivo-surgery-for-renal-anomalies
#4
Thomas B McGregor, Christie Rampersad, Premal Patel
INTRODUCTION: Renal transplantation remains the gold standard treatment for end-stage renal disease, with living donor kidneys providing the best outcomes in terms of allograft survival. As the number of patients on the waitlist continues to grow, solutions to expand the donor pool are ongoing. A paradigm shift in the eligibility of donors with renal anomalies has been looked at as a potential source to expand the living donor pool. We sought to determine how many patients presented with anatomic renal anomalies at our transplant centre and describe the ex-vivo surgical techniques used to render these kidneys suitable for transplantation...
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/26579303/controversies-related-to-living-kidney-donors
#5
REVIEW
Ahmed I Kamal, Ahmed M Harraz, Ahmed A Shokeir
BACKGROUND: Increasing the living-donor pool by accepting donors with an isolated medical abnormality (IMA) can significantly decrease the huge gap between limited supply and rising demand for organs. There is a wide range of variation among different centres in dealing with these categories of donors. We reviewed studies discussing living kidney donors with IMA, including greater age, obesity, hypertension, microscopic haematuria and nephrolithiasis, to highlight the effect of these abnormalities on both donor and recipient sides from medical and surgical perspectives...
December 2011: Arab Journal of Urology
https://www.readbyqxmd.com/read/26398654/pelvic-kidney-for-living-transplantation-case-report-and-review-of-the-literature
#6
REVIEW
Tobias August Siemens, Itamara Pereira Danucalov, Alexandre Tortoza Bignelli, Sílvia Regina Hokazono, Luiz Sérgio Santos, Fernando Meyer, Ziliane Caetano Lopes Martins, Miguel Carlos Riella
INTRODUCTION: The difference between available kidneys and the number of patients on waiting list for kidney transplantation continues to grow. For this reason the trend is to use donors with expanded criteria, such as a pelvic kidney, as we describe below. CASE REPORT: Male patient 25 years-old with end-stage kidney disease, receives as a graft a pelvic kidney from his father, 49 years-old, known to have controlled systemic arterial hypertension and nephrolithiasis by history without new episodes in the last 10 years...
July 2015: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/26252291/left-lateral-sectionectomy-of-the-native-liver-and-combined-living-related-liver-kidney-transplantation-for-primary-hyperoxaluria-type-1
#7
Guo-Yong Chen, Si-Dong Wei, Zhong-Wu Zou, Gao-Feng Tang, Jian-Jun Sun, Shao-Tang Zhou
Primary hyperoxaluria type I (PH1), the most severe form of primary hyperoxalurias, is a liver disease of the metabolic defect in glyoxylate detoxification that can be corrected by liver transplantation. A 21-year-old man presented to our center after 4 months of regular hemodialysis for kidney failure caused by nephrolithiasis. A diagnosis of PH1 was confirmed by mutations of the AGXT gene. Left lateral sectionectomy of the native liver was performed; and auxiliary partial orthotopic liver transplantation (APOLT) and kidney transplantation were carried out synchronously using a living donor...
August 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/25833662/minimally-invasive-treatment-of-renal-transplant-nephrolithiasis
#8
He-jia Yuan, Dian-dong Yang, Yuan-shan Cui, Chang-ping Men, Zhen-li Gao, L Shi, Ji-tao Wu
PURPOSE: Urolithiasis is a rare complication of renal transplantation, and there is limited evidence to guide treatment. Management of stones in the transplanted kidney can be challenging. We present our experience in treating upper urinary tract (UUT) allograft lithiasis using minimally invasive procedures, with the aim of demonstrating their efficacy and safety in renal transplant recipients. METHODS: The records of 1615 patients undergoing kidney transplantation and follow-up in our center between August 2000 and July 2014 were reviewed...
December 2015: World Journal of Urology
https://www.readbyqxmd.com/read/25633514/preliminary-assessment-of-interand-intraobserver-reproducibility-and-normative-values-of-renal-mean-transit-time-mtt-and-parenchymal-transit-time-ptt-for-99mtc-etylenodicysteine
#9
Paweł Cichocki, Marian Surma, Wojciech Woźnicki, Małgorzata Bieńkiewicz, Anna Płachcińska, Jacek Kuśmierek
BACKGROUND: The clinical significance of MTT and PTT, determined by deconvolution of renographic curves, is arguable. Their usefulness in diagnosis of obstructive uro- and nephropathy, renovascular hypertension and monitoring of transplanted kidneys is pointed out, but susceptibility of deconvolution methods to errors resulting from "statistical noise" is also stressed. So far there are no reports on normative MTT values for 99mTc-EC, although such values were already determined for ¹³¹I-OIH, 99mTc-DTPA and 99mTc-MAG3...
2015: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/25366522/familial-hypomagnesemia-with-hypercalciuria-and-nephrocalcinosis-variable-phenotypic-expression-in-three-affected-sisters-from-mexican-ancestry
#10
María E Arteaga, Walter Hunziker, Audrey S M Teo, Axel M Hillmer, Osvaldo M Mutchinick
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis is a rare autosomal recessive renal disease caused by mutations in genes for the tight junction transmembrane proteins Claudin-16 (CLDN16) and Claudin-19 (CLDN19). We present the first case report of a Mexican family with three affected sisters carrying a p.Gly20Asp mutation in CLDN19 whose heterozygous mother showed evident hypercalciuria and normal low magnesemia without any other clinical, laboratory, and radiological symptoms of renal disease making of her an unsuitable donor...
February 2015: Renal Failure
https://www.readbyqxmd.com/read/24261656/stone-disease-in-living-related-renal-donors-long-term-outcomes-for-transplant-donors-and-recipients
#11
Emad Rizkala, Sarah Coleman, Christine Tran, Wahib Isac, Stuart M Flechner, David Goldfarb, Manoj Monga
BACKGROUND AND PURPOSE: Historically, patients wishing to donate their kidney to living related recipients were deemed ineligible if preoperative imaging demonstrated nephrolithiasis. We assess the outcomes of donors with nephrolithiasis and the outcomes of their recipients. METHODS: Donors undergoing nephrectomy between 2001 and 2011 who had nephrolithiasis on preoperative computed tomography (CT) imaging or a history of stone passage were identified. A retrospective chart review documented donor and recipient demographics, donor 24-hour urine collections, stone size and location, stone events after transplant, and graft function...
December 2013: Journal of Endourology
https://www.readbyqxmd.com/read/23998720/stone-disease-in-living-related-renal-donors-long-term-outcomes-for-transplant-donors-and-recipients
#12
Emad Rizkala, Sarah Coleman, Christine Tran, Wahib Isac, Stuart M Flechner, David Goldfarb, Manoj Monga
Introduction: Historically patients wishing to donate their kidney to living related recipients were deemed ineligible if pre-operative imaging demonstrated nephrolithiasis. We assess the outcomes of donors with nephrolithiasis and the outcomes of their recipients. Methods: Donors undergoing nephrectomy between 2001-2011 who had nephrolithiasis on preoperative CT imaging or a history of stone passage were identified. A retrospective chart review documented donor and recipient demographics, donor 24-hour urine collections, stone size and location, stone events following transplant and graft function...
September 2, 2013: Journal of Endourology
https://www.readbyqxmd.com/read/23026596/lithiasis-in-1-313-kidney-transplants-incidence-diagnosis-and-management
#13
M Ferreira Cassini, A J Cologna, M Ferreira Andrade, G J Lima, U Medeiros Albuquerque, A C Pereira Martins, S Tucci Junior
BACKGROUND: Renal transplantation remains the optimal treatment of patients with end-stage renal disease. Urinary lithiasis represents an unusual urologic complication in renal transplantation, with an incidence of <1%. Today, recipients of kidneys from deceased donors are more likely to receive grafts with undiagnosed lithiasis, which does not occur in patients from living donors, owing to screening with computerized tomography. OBJECTIVE: The aim of this study was to evaluate the incidence, diagnosis, and therapeutic management of renal lithiasis in transplanted kidneys at a single institution...
October 2012: Transplantation Proceedings
https://www.readbyqxmd.com/read/22922835/adult-with-primary-hyperoxaluria-type-1-regrets-not-receiving-preemptive-liver-transplantation-during-childhood-report-of-a-case
#14
Tomohide Hori, Toshimi Kaido, Nobuyuki Tamaki, Yasuko Toshimitsu, Kohei Ogawa, Shinji Uemoto
A 32-year-old male was suspected to have primary hyperoxaluria type 1 (PH1) and eventually underwent liver transplantation (LT). He was diagnosed with nephrolithiasis at 9 years of age. Right heminephrectomy was performed for a staghorn calculus. He underwent urethrotomy for urinary retention at 12 years of age. Percutaneous nephrolithotomy was performed for nephrolithiasis when he was 16 years of age. He underwent frequent extracorporeal shock wave lithotripsy for recurrent nephrolithiasis from 18 to 24 years of age...
October 2013: Surgery Today
https://www.readbyqxmd.com/read/22755404/living-donor-kidney-transplantation-at-the-university-of-michigan
#15
David D Lee, Christie W Gooden, Satish N Nadig, Christopher J Sonnenday, Chad Abbott, John C Magee, Michael J Englesbe, Jeff D Punch, Milagros Samaniego, Robert M Merion, Randall S Sung
Since renal transplantation is the definitive therapy for most patients with end stage renal disease, we have the challenge of meeting the needs of this rapidly growing population. Currently greater than 1000 patients are waiting for kidney transplantation at the University of Michigan. To meet this demand we have aggressively expanded the donor pool from both deceased and living donors. The focus of this update has been the evolving living donor program at the University of Michigan. In light of the rising rates of obesity in America, we have developed a specialized evaluation to assess potential obese donors...
2011: Clinical Transplants
https://www.readbyqxmd.com/read/22555113/practice-patterns-in-evaluation-of-living-kidney-donors-in-united-network-for-organ-sharing-approved-kidney-transplant-centers
#16
Amarpali Brar, Rahul M Jindal, Kevin C Abbott, Frank P Hurst, Moro O Salifu
INTRODUCTION: The current pattern of evaluation for living kidney donors was investigated. METHODS: We designed a 37-question electronic survey to collect information about living kidney donor evaluation. Of the 181 United Network for Organ Sharing (UNOS)-approved centers, 72 responded. Survey responses were coded and downloaded into SPSS. Data was expressed as means and standard deviations or the percentage of centers with specific responses. RESULTS: 66% of the centers used a cut-off of <80 ml/min for exclusion of living kidney donors...
2012: American Journal of Nephrology
https://www.readbyqxmd.com/read/22168332/incidental-kidney-stones-a-single-center-experience-with-kidney-donor-selection
#17
Irene K Kim, Jane C Tan, Jessica Lapasia, Arvand Elihu, Stephan Busque, Marc L Melcher
The presence of kidney stones has been a relative contraindication for living donation. With the widespread use of more sensitive imaging techniques as part of the routine living donor workup, kidney stones are more frequently detected, and their clinical significance in this setting is largely unknown. Records from 325 potential kidney donors who underwent MRA or CT-angiography were reviewed; 294 proceeded to donation. The prevalence of kidney stones found incidentally during donor evaluation was 7.4% (24 of 325)...
July 2012: Clinical Transplantation
https://www.readbyqxmd.com/read/22050494/renal-transplant-lithiasis-analysis-of-our-series-and-review-of-the-literature
#18
REVIEW
Konstantinos G Stravodimos, Stefanos Adamis, Stavros Tyritzis, Zavos Georgios, Constantinos A Constantinides
BACKGROUND AND PURPOSE: Renal transplant lithiasis represents a rather uncommon complication. Even rare, it can result in significant morbidity and a devastating loss of renal function if obstruction occurs. We present our experience with graft lithiasis in our series of renal transplantations and review the literature regarding the epidemiology, pathophysiology, and current therapeutic strategies in the management of renal transplant lithiasis. PATIENTS AND METHODS: In a retrospective analysis of a consecutive series of 1525 renal transplantations that were performed between January 1983 and March 2007, 7 patients were found to have allograft lithiasis...
January 2012: Journal of Endourology
https://www.readbyqxmd.com/read/21959214/screening-and-follow-up-of-living-kidney-donors-a-systematic-review-of-clinical-practice-guidelines
#19
REVIEW
Allison Tong, Jeremy R Chapman, Germaine Wong, Jeanine de Bruijn, Jonathan C Craig
To minimize the health risks faced by living kidney donors, multiple clinical practice guidelines have been developed on the assessment and care of potential donors. This study aims to compare the quality, scope, and consistency of these guidelines. We searched for guidelines on living kidney donation in electronic databases, guideline registries, and relevant Web sites to February 21, 2011. Methodological quality was assessed using the Appraisal of Guidelines for Research and Education (AGREE) instrument. Textual synthesis was used to compare guideline recommendations...
November 15, 2011: Transplantation
https://www.readbyqxmd.com/read/21711138/ex-vivo-ureteroscopy-at-the-time-of-live-donor-nephrectomy
#20
George R Schade, J Stuart Wolf, Gary J Faerber
BACKGROUND AND PURPOSE: Potential transplant renal allograft recipients exceed the number of donors. Our institution now considers patients with small, unilateral, nonobstructing, incidental renal calculi for possible renal donation. We adopted ex-vivo ureteroscopy (ExURS) to render these kidneys stone free at the time of renal transplantation. We examined the safety and efficacy of ExURS. PATIENTS AND METHODS: After confirming a lack of significant metabolic defects on 24-hour urinalysis, 23 patients with small nonobstructing unilateral nephrolithiasis detected on preoperative CT angiography underwent donor nephrectomy...
September 2011: Journal of Endourology
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