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https://www.readbyqxmd.com/read/30110348/differences-in-clinical-features-and-dengue-severity-between-local-and-migrant-chinese-with-dengue-infection-in-singapore
#1
Chuanhui Xu, Junxiong Pang, Jung Pu Hsu, Yee Sin Leo, David Chien Boon Lye
Dengue is endemic in Singapore but not China. We compared clinical features and disease severity of dengue between local and migrant Chinese, most of whom were construction workers, in Singapore. A retrospective study with all hospitalized dengue patients from 2005 to 2008 were performed, including 2609 local and 1195 migrant Chinese. Compared with local Chinese, migrant Chinese were younger. There were more males, but fewer had comorbidities. Migrant Chinese had more headache, eye pain, nausea and myalgia...
2018: PloS One
https://www.readbyqxmd.com/read/30109950/assessment-of-right-ventricular-function-in-the-research-setting-knowledge-gaps-and-pathways-forward-an-official-american-thoracic-society-research-statement
#2
Tim Lahm, Ivor S Douglas, Stephen L Archer, Harm J Bogaard, Naomi C Chesler, Francois Haddad, Anna R Hemnes, Steven M Kawut, Jeffrey A Kline, Todd M Kolb, Stephen C Mathai, Olaf Mercier, Evangelos D Michelakis, Robert Naeije, Rubin M Tuder, Corey E Ventetuolo, Antoine Vieillard-Baron, Norbert F Voelkel, Anton Vonk-Noordegraaf, Paul M Hassoun
BACKGROUND: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive syndromes is a significant determinant of short- and long-term outcomes. Although remarkable progress has been made in the understanding of RV function and failure since the meeting of the NIH Working Group on Cellular and Molecular Mechanisms of Right Heart Failure in 2005, significant gaps remain at many levels in the understanding of cellular and molecular mechanisms of RV responses to pressure and volume overload, in the validation of diagnostic modalities, and in the development of evidence-based therapies...
August 15, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/30109852/-clinical-guidelines-for-the-management-of-schizophrenia-%C3%AE-%C3%AE-community-service-level-interventions-and-the-role-of-primary-care
#3
M Margariti, M Hadjulis, M Lazaridou, G F Angelidis, V Fotopoulos, L Markaki, F Koulouri
Schizophrenia is one of the most disabling disorders globally, with a significant impact on the professional, social and personal functioning of those affected. Mortality rates are estimated to be 2-2.5 times greater than in the general population attributable to not only suicide but also physical illnesses, such as cardiovascular, metabolic and infectious diseases. Patients with schizophrenia have increased needs for health services which vary according to the stage of the illness and the way the disorder affects the patient...
April 2018: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/30109730/individualization-process-of-the-standardized-care-plan-in-acute-care-hospitalization-units-study-protocol
#4
Mònica Castellà-Creus, Pilar DELGado-Hito, Isabel Andrés-Martínez, Maria-Eulàlia Juvé-Udina
AIM: To understand the individualization process of the standardized care plan that nurses design for hospitalized patients. BACKGROUND: To apply the nursing process, it is advisable to use standardized care plans to standardize the diagnosis, planning and assessment stages. However, the fundamental element of this methodology is the individualization of the care plan. DESIGN: A qualitative study, framed within the constructivist paradigm and applying the Grounded Theory method, in accordance with Strauss and Corbin's approach...
August 14, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/30109455/the-implementation-of-a-longitudinal-pocus-curriculum-for-physicians-working-at-rural-outpatient-clinics-in-chiapas-mexico
#5
Annie Heffernan Rominger, Gerardo Antonio Aguilar Gomez, Patrick Elliott
BACKGROUND: Medical care in resource limited settings is challenging, particularly with limited access to diagnostic and imaging studies. The most portable and cost effective diagnostic imaging in these areas is ultrasound. Ultrasound is a very teachable skill with a short, single intensive training course and hands-on teaching; however, there are limited data on a longitudinal point-of-care ultrasound (POCUS) curriculum in resource limited settings. The goal of this intervention is to develop an effective longitudinal POCUS curriculum for local physicians working in rural clinics in the state of Chiapas, Mexico, and evaluate its effectiveness on patient care...
August 15, 2018: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/30109437/latest-clinical-recommendations-on-valproate-use-for-migraine-prophylaxis-in-women-of-childbearing-age-overview-from-european-medicines-agency-and-european-headache-federation
#6
Efstratia Vatzaki, Sabine Straus, Jean-Michel Dogne, Juan Garcia Burgos, Thomas Girard, Paolo Martelletti
Migraine is a common and burdensome neurological condition which affects mainly female patients during their childbearing years. Valproate has been widely used for the prophylaxis of migraine attacks and is also included in the main European Guidelines. Previous (2014) European recommendations on limiting the use of valproate in women of childbearing age did not achieve their objective in terms of limiting the use of valproate in women of childbearing age and raising awareness regarding the hazardous effect of valproate to children exposed in utero...
August 14, 2018: Journal of Headache and Pain
https://www.readbyqxmd.com/read/30109278/operating-room-staff-and-surgeon-documentation-curriculum-improves-wound-classification-accuracy
#7
Joseph W Gorvetzian, Katharine E Epler, Samuel Schrader, Joshua M Romero, Ronald Schrader, Alissa Greenbaum, Rohini McKee
Background: Misclassification of wounds in the operating room (OR) can adversely affect surgical site infection (SSI) reporting and reimbursement. This study aimed to measure the effects of a curriculum on documentation of surgical wound classification (SWC) for operating room staff and surgeons. Methods: Accuracy of SWC was determined by comparing SWC documented by OR staff during the original operation to SWC determined by in-depth chart review. Patients 18 years or older undergoing inpatient surgical procedures were included...
August 2018: Heliyon
https://www.readbyqxmd.com/read/30109239/prevalence-of-posttraumatic-stress-disorder-symptoms-among-young-athletes-after-anterior-cruciate-ligament-rupture
#8
Ajay S Padaki, Manish S Noticewala, William N Levine, Christopher S Ahmad, Michael K Popkin, Charles A Popkin
Background: The risk of depression and the fear of reinjury were documented in recent investigations of patients after anterior cruciate ligament (ACL) ruptures. The extent of psychological trauma accompanying these injuries among young athletes, however, has never been assessed. Hypothesis: Posttraumatic stress disorder (PTSD) symptoms after ACL injury are present among young athletes with high athletic identities. Study Design: Case series; Level of evidence, 4...
July 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/30109157/construction-of-an-electrocardiogram-database-including-12-lead-waveforms
#9
Dahee Chung, Junggu Choi, Jong-Hwan Jang, Tae Young Kim, JungHyun Byun, Hojun Park, Hong-Seok Lim, Rae Woong Park, Dukyong Yoon
Objectives: Electrocardiogram (ECG) data are important for the study of cardiovascular disease and adverse drug reactions. Although the development of analytical techniques such as machine learning has improved our ability to extract useful information from ECGs, there is a lack of easily available ECG data for research purposes. We previously published an article on a database of ECG parameters and related clinical data (ECG-ViEW), which we have now updated with additional 12-lead waveform information...
July 2018: Healthcare Informatics Research
https://www.readbyqxmd.com/read/30109151/temporal-segmentation-for-capturing-snapshots-of-patient-histories-in-korean-clinical-narrative
#10
Wangjin Lee, Jinwook Choi
Objectives: Clinical discharge summaries provide valuable information about patients' clinical history, which is helpful for the realization of intelligent healthcare applications. The documents tend to take the form of separate segments based on temporal or topical information. If a patient's clinical history can be seen as a consecutive sequence of clinical events, then each temporal segment can be seen as a snapshot, providing a certain clinical context at a specific moment. This study aimed to demonstrate a temporal segmentation method of Korean clinical narratives for identifying textual snapshots of patient history as a proof-of-a-concept...
July 2018: Healthcare Informatics Research
https://www.readbyqxmd.com/read/30108204/long-term-outcome-of-splanchnic-vein-thrombosis-in-cirrhosis
#11
Marco Senzolo, Nicoletta Riva, Francesco Dentali, Kryssia Rodriguez-Castro, Maria Teresa Sartori, Soo-Mee Bang, Ida Martinelli, Sam Schulman, Adriano Alatri, Jan Beyer-Westendorf, Matteo Nicola Dario Di Minno, Walter Ageno
INTRODUCTION: Little is known about the long-term outcome of cirrhotic patients with splanchnic vein thrombosis (SVT). This prospective cohort study aimed to describe the clinical presentation, bleeding incidence, thrombotic events, and mortality in patients with SVT associated with cirrhosis. METHODS: Among 604 consecutive patients with SVT enrolled over 2 years, 149 had cirrhosis. Major bleeding, thrombotic events, and all-cause mortality were recorded during a 2-year follow-up...
August 15, 2018: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/30108008/optimal-medical-management-before-lower-extremity-bypass-for-claudication-in-the-veteran-population
#12
Christopher R Williams, Angela Jellison, Luke Martin, Chong Zhang, Angela P Presson, Larry W Kraiss, Benjamin S Brooke
OBJECTIVE: Optimizing medical management through glucose control, smoking cessation, and drug therapy (ie, antiplatelet and statin agents) is recommended as first-line therapy for patients with claudication. The aims of this study were to determine how frequently veterans with claudication received optimal medical management (OMM) before undergoing elective open lower extremity bypass procedures nationwide and whether preoperative OMM was associated with improved surgical outcomes. METHODS: We reviewed all patients within the Veterans Affairs (VA) Surgical Quality Improvement Program database who underwent elective open lower extremity bypass procedures for claudication at nationwide VA medical centers from 2005 until 2015...
August 11, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/30107929/isolated-mechanical-aortic-valve-replacement-in-rheumatic-patients-in-a-low-to-middle-income-country
#13
Jacques Scherman, Rodgers Manganyi, Paul Human, Timothy Pennel, Andre Brooks, Johan Brink, Peter Zilla
OBJECTIVE: Although the results of aortic valve replacement are well documented for industrialized countries, the outcome in patients with rheumatic aortic valve disease in low- to middle-income countries is less well explored. The aim of this study was to determine the long-term survival and clinical outcomes after isolated aortic valve replacement in patients with rheumatic heart disease in a Sub-Saharan country where follow-up of indigent patients is often challenging. METHODS: A retrospective review of 969 aortic valve replacements performed between 2003 and 2013 was conducted at Cape Town's Groote Schuur Hospital...
July 20, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/30107889/what-are-the-required-components-of-pre-and-post-test-counseling
#14
REVIEW
Britton D Rink, Jeffrey A Kuller
Prenatal care providers are faced with a myriad of decisions about how to offer genetic screening and testing in ways that are appropriate to their patient population and their workflow. Among the critical issues brought to the forefront of rapidly advancing genetic and genomic technologies is the importance of pre- and post-test counseling. This document is a synthesis of proceedings of a workshop sponsored by the American College of Obstetricians and Gynecologists, the American College of Medical Genetics and Genomics, and the Society for Maternal-Fetal Medicine, on January 24-25, 2017, during which invited experts discussed required components of pre- and post-test counseling and associated concerns in the provision of prenatal care...
July 26, 2018: Seminars in Perinatology
https://www.readbyqxmd.com/read/30107886/predicting-non-home-discharge-in-epithelial-ovarian-cancer-patients-external-validation-of-a-predictive-model
#15
Elizabeth V Connor, Erica M Newlin, J Eric Jelovsek, Mariam M AlHilli
OBJECTIVE: To externally validate a model predicting non-home discharge in women undergoing primary cytoreductive surgery (CRS) for epithelial ovarian cancer (EOC). METHODS: Women undergoing primary CRS via laparotomy for EOC at three tertiary medical centers in an academic health system from January 2010 to December 2015 were included. Patients were excluded if they received neoadjuvant chemotherapy, had a non-epithelial malignancy, were not undergoing primary cytoreduction, or lacked documented model components...
August 11, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/30107875/algorithm-for-treatment-of-chronic-spontaneous-urticaria-with-omalizumab
#16
J Spertino, E Rozas Muñoz, L Curto Barredo, I Figueras Nart, A Gimenez Arnau, E Serra Baldrich, M Bonfill-Ortí, V Expósito-Serrano, A Guilabert, G Melé Ninot, M Villar Buil, J Garcias Ladaria, X García Navarro, M Vilavella, I Bielsa Marsol, G Aparicio Ortiz, C Baliu Piqué, A Álvarez Abella, N Lamas Domenech, J M Mascaró, S Gómez, J I Torné Gutiérrez, A Vicente Villa
BACKGROUND AND OBJECTIVE: Pivotal trials with omalizumab for treatment of chronic spontaneous urticaria (CSU) are generally run over 12 to 24weeks. However, in clinical practice, many patients need longer treatment. In this article, we present an algorithm for treatment with omalizumab. MATERIAL AND METHODS: The consensus document we present is the result of a series of meetings by the CSU working group of "Xarxa d'Urticària Catalana i Balear" (XUrCB) at which data from the recent literature were presented, discussed, compared, and agreed upon...
August 11, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/30107809/the-heidelberg-milestones-communication-approach-mca-for-patients-with-prognosis-12-months-protocol-for-a-mixed-methods-study-including-a-randomized-controlled-trial
#17
Anja Siegle, Matthias Villalobos, Jasmin Bossert, Katja Krug, Laura Hagelskamp, Johannes Krisam, Violet Handtke, Nicole Deis, Jana Jünger, Michel Wensing, Michael Thomas
BACKGROUND: The care needs of patients with a limited prognosis (<12 months median) are complex and dynamic. Patients and caregivers must cope with many challenges, including physical symptoms and disabilities, uncertainty. and compromised self-efficacy. Healthcare is often characterized by disruptions in the transition between healthcare providers. The Milestones Communication Approach (MCA) is a structured, proactive, interprofessional concept that involves physicians and nurses and is aimed at providing coherent care across the disease trajectory...
August 14, 2018: Trials
https://www.readbyqxmd.com/read/30107800/how-and-why-weight-stigma-drives-the-obesity-epidemic-and-harms-health
#18
A Janet Tomiyama, Deborah Carr, Ellen M Granberg, Brenda Major, Eric Robinson, Angelina R Sutin, Alexandra Brewis
BACKGROUND: In an era when obesity prevalence is high throughout much of the world, there is a correspondingly pervasive and strong culture of weight stigma. For example, representative studies show that some forms of weight discrimination are more prevalent even than discrimination based on race or ethnicity. DISCUSSION: In this Opinion article, we review compelling evidence that weight stigma is harmful to health, over and above objective body mass index. Weight stigma is prospectively related to heightened mortality and other chronic diseases and conditions...
August 15, 2018: BMC Medicine
https://www.readbyqxmd.com/read/30107762/comparative-effectiveness-of-avelumab-versus-chemotherapy-in-merkel-cell-carcinoma-innovative-use-of-patient-insights
#19
Murtuza Bharmal, Alexia Marrel, Meliessa Hennessy, Fatoumata Fofana, Jérémy Lambert, Benoit Arnould
AIM: To assess patient experience with chemotherapy and avelumab in metastatic Merkel cell carcinoma (mMCC). METHODS: In the JAVELIN Merkel 200 trial, chemotherapy-refractory mMCC patients could participate in optional qualitative interviews at baseline documenting recollection of previous chemotherapy experience, and at weeks 13/25 documenting current experience with avelumab. Functional Assessment of Cancer Therapy subscale for melanoma questionnaire (FACT-M) was administered in parallel...
August 15, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/30107698/-the-current-review-and-prospects-of-the-genetic-study-and-clinical-treatment-of-adolescent-idiopathic-scoliosis
#20
Y Qiu
This review mainly focused on the etiology and the surgical strategy for adolescent idiopathic scoliosis (AIS) treatment. Genome-wide association study on the etiology of AIS using samples from more than 5 000 patients and 6 000 normal controls showed two genes: LBX1-AS1 on 10q24.32 and TNIK on 3q26.2 highly related to AIS initiation and progression. Regarding the conservative treatment of AIS, bracing is the only well-documented effective non-operative management in the early stage of AIS. For the patients with Cobb angle smaller than 80°, balancing spine, saving fusion level and restoring thoracic kyphosis are the basic objectives in surgical management...
August 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
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