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Amal M Badawoud, Mary Martha Stewart, Margarita Orzolek, Krista L Donohoe, Patricia W Slattum
Objective The resident-directed medication administration program (RDMA) is a personalized medication approach designed to improve the medication administration process in long-term care facilities (LTCFs). This evaluation aimed to document staff experience with the RDMA program compared with staff working in facilities using a facility-directed medication administration program (FDMA). Design This descriptive program evaluation invited staff members to share their experiences with the medication administration process through an anonymous survey...
October 1, 2018: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
Joost Verbeek, Mickaël Hiligsmann, Americo Cicchetti, Marco Marchetti
OBJECTIVES: The emergence of new medical technologies and budget restrictions has led to a substantial increase in the use of hospital-based health technology assessment (HB-HTA). This qualitative study explores whether there is a possibility and interest to realize the collection and dissemination of HB-HTA reports on an international scale by exploring the opinions from HB-HTA experts. METHODS: A survey was designed and sent to an international group of experts knowledgeable in HB-HTA from eighteen different countries...
October 16, 2018: International Journal of Technology Assessment in Health Care
Ludovic Trinquart, Adam G Dunn, Florence T Bourgeois
BACKGROUND: Prospective trial registration is a powerful tool to prevent reporting bias. We aimed to determine the extent to which published randomized controlled trials (RCTs) were registered and registered prospectively. METHODS: We searched MEDLINE and EMBASE from January 2005 to October 2017; we also screened all articles cited by or citing included and excluded studies, and the reference lists of related reviews. We included studies that examined published RCTs and evaluated their registration status, regardless of medical specialty or language...
October 16, 2018: BMC Medicine
Jennifer M Re, Suzanne Dean, Jimmy Mullaert, Antoine Guedeney, Samuel Menahem
BACKGROUND: Mothers and infants are exposed to multiple stresses when cardiac surgery is required for the infant. This study reviewed infant responsiveness using a standardized objective observational measure of social withdrawal and explored its association with measures of maternal distress. METHODS: Mother-infant pairs involving infants surviving early cardiac surgery were assessed when the infant was aged two months. Infant social withdrawal was measured using the Alarm Distress Baby Scale...
November 2018: World Journal for Pediatric & Congenital Heart Surgery
Mallik Greene, Chakkarin Burudpakdee, Michael Behling, Arpamas Seetasith, Holly Krasa
OBJECTIVE: Patient support programs, such as the ASSURE Program for long-acting injectable aripiprazole, are designed to help support access to medications, including long-acting injectable (LAI) antipsychotics for patients with schizophrenia. We conducted the study to evaluate adherence to long-acting injectable aripiprazole among patients utilizing the program local care centers (LCC). METHODS: We utilized data collected from participating LCC between October 2014 and February 2018...
October 16, 2018: Current Medical Research and Opinion
Samaher Sweity, Andrew Finlay, Charlotte Lees, Adam Monk, Toshi Sherpa, Derick Wade
OBJECTIVE: To determine the short-term effects of supplying hospital inpatients with earplugs and eye masks, preparatory to a full-scale trial. DESIGN: A single-centre, open-label, two-arm, parallel group, randomized-controlled trial. SETTING: A total of 13 medical and surgical wards in a large teaching hospital in the United Kingdom. PARTICIPANTS: Everyone admitted to hospital aged 18 years or older, who stayed overnight and had the mental capacity and sufficient understanding of English to give consent, the ability to complete the study questionnaire and the ability to use earplugs and eye masks unaided was considered...
October 15, 2018: Clinical Rehabilitation
Lorraine Johnson, Mira Shapiro, Jennifer Mankoff
Lyme disease is caused by the bacteria borrelia burgdorferi and is spread primarily through the bite of a tick. There is considerable uncertainty in the medical community regarding the best approach to treating patients with Lyme disease who do not respond fully to short-term antibiotic therapy. These patients have persistent Lyme disease symptoms resulting from lack of treatment, under-treatment, or lack of response to their antibiotic treatment protocol. In the past, treatment trials have used small restrictive samples and relied on average treatment effects as their measure of success and produced conflicting results...
October 12, 2018: Healthcare (Basel, Switzerland)
Francesco Di Gennaro, Luigi Pisani, Nicola Veronese, Damiano Pizzol, Valeria Lippolis, Annalisa Saracino, Laura Monno, Michaëla A M Huson, Roberto Copetti, Giovanni Putoto, Marcus J Schultz
Background : Chest ultrasound (CUS) has been shown to be a sensitive and specific imaging modality for pneumothorax, pneumonia, and pleural effusions. However, the role of chest ultrasound in the diagnosis of thoracic tuberculosis (TB) is uncertain. We performed a systematic search in the medical literature to better define the potential role and value of chest ultrasound in diagnosing thoracic tuberculosis. Aim : To describe existing literature with regard to the diagnostic value of chest ultrasound in thoracic tuberculosis...
October 12, 2018: International Journal of Environmental Research and Public Health
Guilherme H Saito, Austin E Sanders, Martin J O'Malley, Jonathan T Deland, Scott J Ellis, Constantine A Demetracopoulos
BACKGROUND: Patient-specific instrumentation (PSI) for TAA is a novel technology with several potential benefits. The primary goal of this study was to compare the use of PSI with the standard referencing guide (SRG) in regards to accuracy of tibial implant positioning. Operative time, fluoroscopy time and accuracy of PSI preoperative reports were also evaluated. METHODS: A retrospective analysis of 99 patients who underwent a primary TAA with the INFINITY prosthesis (Wright Medical, Memphis, TN) was performed...
February 16, 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Nicola Krähenbühl, Maxwell W Weinberg, Beat Hintermann, Justin M Haller, Charles L Saltzman, Alexej Barg
BACKGROUND: Chronic injuries of the distal tibio-fibular syndesmosis often present with non-specific clinical and radiographic findings. If chronic instability to the distal tibio-fibular syndesmosis is verified, various reconstruction options are available. The purpose of this article is to give a systematic review of current surgical treatment options in patients with chronic syndesmotic injury. METHODS: Three major medical databases were searched from inception through December 12, 2017: PubMed, ScienceDirect, and SpringerLink...
August 30, 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Melissa Anne Wright, Daniel Steffens, Ravi Lee Huilgol
BACKGROUND: The prevalence of peripheral arterial disease (PAD) in Australia is currently poorly characterized. The risk factor profile for PAD is changing with the population ageing, diabetes increasing and smoking rates declining. The management of PAD is also evolving, with advances in medical management and endovascular technique. The trends in PAD prevalence and surgical management have implications for preventative medicine, the Australian health system and vascular surgery. We report and analyse trends in PAD surgical intervention performed between 2001 and 2015...
October 15, 2018: ANZ Journal of Surgery
Peter Langhorne, Janice M Collier, Patricia J Bate, Matthew Nt Thuy, Julie Bernhardt
BACKGROUND: Very early mobilisation (VEM) is performed in some stroke units and recommended in some acute stroke clinical guidelines. However, it is unclear whether very early mobilisation independently improves outcome after stroke. OBJECTIVES: To determine whether very early mobilisation (started as soon as possible, and no later than 48 hours after onset of symptoms) in people with acute stroke improves recovery (primarily the proportion of independent survivors) compared with usual care...
October 16, 2018: Cochrane Database of Systematic Reviews
Jan Nilsson, Maria Engström, Jan Florin, Ann Gardulf, Marianne Carlsson
BACKGROUND: The Nurse Professional Competence (NPC) Scale with 88-items has been used to measure self-reported competence among nursing students and registered nurses in many national and international nursing research projects. However, a shorter version of the scale with maintained quality has been requested to further enhance its usability. OBJECTIVES: To develop and evaluate the construct validity and internal consistency of a shorter version of the NPC Scale...
September 29, 2018: Nurse Education Today
Ashraf F Hefny, Adel Z Ayad, Nikolay Matev, Masoud O Bashir
INTRODUCTION: Psyllium in granular dosage form is used as an over - the counter safe laxative drug. It has a considerable hygroscopic propriety which allows it to retain water and expands rapidly to become many times of its original size. PRESENTATION OF THE CASE: 21-year-old man presented to the Emergency Department complaining of lower abdominal pain and constipation for five days. He was discharged home on Psyllium for treatment of the constipation. Two days later, he returned to the Emergency Department complaining of increased abdominal distension without passing any stools...
October 8, 2018: International Journal of Surgery Case Reports
Su Woan Wo, Lai Choo Ong, Wah Yun Low, Pauline Siew Mei Lai
Because of the nature of epilepsy, and the unpredictability of seizure recurrence, epilepsy requires long-term treatment with medications. As a consequence, epilepsy has a negative pervasive impact in children with epilepsy (CWE), and their parents. Hence, our aim was to explore the needs and challenges of parents and their CWE. In-depth interviews (IDIs) were conducted with 15 families (12 mothers and 3 fathers) and 15 CWE (aged 8-18 years). Data were transcribed verbatim and thematically analyzed using the descriptive phenomenology approach...
October 12, 2018: Epilepsy & Behavior: E&B
Alisson R Teles, Spencer Montgomery, Kenneth C Thomas
BACKGROUND: Necrotizing fasciitis (NF) is a surgical diagnosis characterized by a rapidly progressive soft tissue infection, widespread tissue necrosis, and associated systemic illness. Friability of the superficial fascia, dishwater-gray exudate, and absence of pus are surgical characteristics of this diagnosis. Due to the rapid progression of the infection, early recognition and aggressive surgical debridement are crucial to reduce mortality. Despite being commonly seen by general, plastic, and orthopedic surgeons, NF is an extremely rare spine surgery emergency...
October 12, 2018: World Neurosurgery
Saumya M Shah, Jennifer M Martinez-Thompson, Nancy N Diehl, Brian G Mohney
PURPOSE: To describe the prevalence and clinical features of a common but underrecognized disorder of adult vertical strabismus. METHODS: The medical records of all adult (>19 years of age) residents of Olmsted County, Minnesota, diagnosed with nonparalytic, small-angle hypertropia (NPSAH) from January 1, 1985, through December 31, 2004, were retrospectively reviewed for demographic and clinical features. RESULTS: Of 753 patients diagnosed with adult-onset strabismus, 99 (13...
October 12, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
M Sheikh Mohamed, Srivani Veeranarayanan, Toru Maekawa, D Sakthi Kumar
Cancer is a highly intelligent system of cells, that works together with the body to thrive and subsequently overwhelm the host in order for its survival. Therefore, treatment regimens should be equally competent to outsmart these cells. Unfortunately, it is not the case with current therapeutic practices, the reason why it is still one of the most deadly adversaries and an imposing challenge to healthcare practitioners and researchers alike. With rapid nanotechnological interventions in the medical arena, the amalgamation of diagnostic and therapeutic functionalities into a single platform, theranostics provides a never before experienced hope of enhancing diagnostic accuracy and therapeutic efficiency...
October 12, 2018: Advanced Drug Delivery Reviews
Sarah A Mbayei, Amanda Faulkner, Christine Miner, Karen Edge, Victor Cruz, Sandra A Peña, Kathy Kudish, Joan Coleman, Eva Pradhan, Stepy Thomas, Stacey Martin, Tami H Skoff
Background: The incidence of pertussis in the United States has increased in recent years. While characteristics of severe pertussis infection have been described in infants, fewer data are available in older children and adults. In this analysis, we characterize pertussis infections in hospitalized patients of all ages. Methods: Cases of pertussis with cough onset from January 1, 2011 through December 31, 2015 from 7 U.S. Emerging Infections Program Network states were reviewed...
October 15, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Margreet S H Wortman, Joran Lokkerbol, Johannes C van der Wouden, Bart Visser, Henriëtte E van der Horst, Tim C Olde Hartman
BACKGROUND: In primary and secondary care medically unexplained symptoms (MUS) or functional somatic syndromes (FSS) constitute a major burden for patients and society with high healthcare costs and societal costs. Objectives were to provide an overview of the evidence regarding the cost-effectiveness of interventions for MUS or FSS, and to assess the quality of these studies. METHODS: We searched the databases PubMed, PsycINFO, the National Health Service Economic Evaluation Database (NHS-EED) and the CEA registry to conduct a systematic review...
2018: PloS One
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