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https://www.readbyqxmd.com/read/30303048/culturing-practices-and-the-care-of-the-urinary-catheter-in-reducing-nhsn-defined-catheter-associated-urinary-tract-infections-the-tale-of-two-teaching-hospitals
#1
Ana Cecilia Bardossy, Takiah Williams, Karen Jones, Susan Szpunar, Marcus Zervos, George Alangaden, Katherine Reyes, Mohamad G Fakih
We compared interventions to improve urinary catheter care and urine culturing in adult intensive care units of 2 teaching hospitals. Compared to hospital A, hospital B had lower catheter utilization, more compliance with appropriate indications and maintenance, but higher urine culture use and more positive urine cultures per 1,000 patient days.
October 10, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/30295792/rcpaqap-audit-of-antimicrobial-reporting-in-australian-and-new-zealand-laboratories-opportunities-for-laboratory-contribution-to-antimicrobial-stewardship
#2
Maryza Graham, Debra A Walker, Elizabeth Haremza, Arthur J Morris
Objectives: A 2017 laboratory survey conducted by the Royal College of Pathologists of Australasia Quality Assurance Programs (RCPAQAP) asked participants which antimicrobials they would report for given organisms in either blood or urine cultures in order to identify opportunities for improvement of antimicrobial reporting. Methods: Over-reporting was defined as reporting of broad-spectrum antimicrobials on isolates susceptible to narrow-spectrum antimicrobials...
October 5, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/30292891/does-the-use-of-adjunct-urine-lam-in-hiv-infected-hospitalized-patients-reduce-the-utilization-of-health-care-resources-a-post-hoc-analysis-of-the-lam-multi-country-randomized-control-trial
#3
Poobalan Naidoo, Aliasgar Esmail, Jonathan G Peter, Malika Davids, Mohammed Fadul, Keertan Dheda
BACKGROUND: The World Health Organisation (WHO) recommends the use of adjunctive urine lipopolysaccharide lipoarabinomannan (LAM) testing in hospitalized HIV-infected persons with suspected tuberculosis (TB) and a CD4 count <100 cells/ml. However, the recommendation is conditional and uptake by individual treatment programs depends on perceived additional benefit. The aim of this study was to determine if adjunctive LAM testing had additional clinical benefits including reduction in health care-related use of resources...
October 4, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/30236062/urine-cultures-in-a-long-term-care-facility-ltcf-time-for-improvement
#4
J Haaijman, E E Stobberingh, L W van Buul, C M P M Hertogh, H Horninge
BACKGROUND: Urinary tract infections (UTIs) are the most prevalent infections in long-term care facilities (LTCFs). Numerous studies have described the problem of inadequate UTI diagnosis and treatment. We assessed the role of urine cultures in the diagnosis and treatment of UTIs in a LTCF. METHODS: In a 370-bed non-academic LTCF a retrospective assessment of antibiotic (AB) prescriptions for UTIs and urine cultures was performed from July 2014 to January 2016. The reasons why physicians, including 11 nursing home physicians and 2 junior doctors, ordered urine cultures were recorded using questionnaires...
September 20, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/30209351/urinary-tract-infection-is-common-in-vlbw-infants
#5
Caitlin M Drumm, Javedan N Siddiqui, Sameer Desale, Jayashree Ramasethu
OBJECTIVE: Determine the significance of urinary tract infection (UTI) as a cause of late onset sepsis (LOS) in very low birth weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU). STUDY DESIGN: Analysis of blood, cerebrospinal fluid and urine culture results in VLBW infants >72-h old, admitted to the Georgetown University Hospital NICU between 2005 and 2015. RESULT: Of 527 VLBW infants, 297 (56.4%) underwent 911 evaluations for LOS; only one-third included urine cultures...
September 12, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/30186011/a-prospective-study-of-fungal-colonization-and-invasive-fungal-disease-in-long-term-mechanically-ventilated-patients-in-a-respiratory-intensive-care-unit
#6
Amartya Chakraborti, Anand Jaiswal, Pushpendra Kumar Verma, Ritu Singhal
Background: Long-term mechanical ventilation in an Intensive Care Unit (ICU) exposes the patient to fungal colonization and invasive fungal disease due to the presence of indwelling catheters, administration of broad-spectrum antibiotics, and intravenous corticosteroids. A study is hence required to study the risk factors and incidence of fungal infection in these patients. Methods: A prospective observational study was carried out in the respiratory ICU of a tertiary care hospital for a period of approximately 1 year in which patients on mechanical ventilation (>7 days) were enrolled...
August 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/30182079/clinical-characteristics-of-postoperative-febrile-urinary-tract-infections-after-ureteroscopic-lithotripsy
#7
Jin Woo Kim, You Jin Lee, Jae-Wook Chung, Yun-Sok Ha, Jun Nyung Lee, Eun Sang Yoo, Tae Gyun Kwon, Bum Soo Kim
Purpose: Ureteroscopic lithotripsy (URS) is gaining popularity for the management of ureteral stones and even renal stones, with high efficacy and minimal invasiveness. Although this procedure is known to be safe and to have a low complication rate, febrile urinary tract infection (UTI) after URS is not rare. Therefore, we aimed to analyze the risk factors and causative pathogens of febrile UTI after URS. Materials and Methods: Between January 2013 and June 2015, 304 patients underwent URS for ureteral or renal stones...
September 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/30116443/acute-hepatic-failure-and-epididymitis-in-a-hispanic-patient-with-active-systemic-lupus-erythematosus
#8
Beau M Bailey, Kenneth S Ramos, Alice Johnson, Charlene Mitchell
Systemic lupus erythematosus (SLE) is an autoimmune disease known to affect a variety of organ systems. Patients with SLE are more prone to developing common infections that can mimic the complications of SLE. As such, it is essential to differentiate complications of SLE from infection to ensure appropriate management and to improve morbidity and mortality of this patient population. Here we present a 24-year-old, Hispanic male, with SLE complicated by dialysis-dependent end-stage renal disease and dilated cardiomyopathy...
September 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/30094005/-myroides-odoratimimus-urinary-tract-infection-in-an-immunocompromised-patient-an-emerging-multidrug-resistant-micro-organism
#9
Giovanni Lorenzin, Giorgio Piccinelli, Lucrezia Carlassara, Francesco Scolari, Francesca Caccuri, Arnaldo Caruso, Maria Antonia De Francesco
Background: Myroides spp. are common environmental organisms and they can be isolated predominantly in water, soil, food and in sewage treatment plants. In the last two decades, an increasing number of infections such as urinary tract infections and skin and soft tissue infections, caused by these microorganisms has been reported. Selection of appropriate antibiotic therapy to treat the infections caused by Myroides spp . is difficult due to the production of a biofilm and the organism's intrinsic resistance to many antibiotic classes...
2018: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/30078966/direct-identification-and-susceptibility-testing-of-gram-negative-bacilli-from-turbid-urine-samples-using-vitek2
#10
Neelima Angaali, Laxmi Vemu, Chavali Padmasri, Neeraja Mamidi, Vijay Dharma Teja
INTRODUCTION: Urinary tract infections (UTIs) are the most common infectious diseases occurring in either the community or healthcare setting. Turnaround time for urine culture is about 24 h, and antimicrobial susceptibility testing (AST) requires another 24 h. Consequently, initial antibiotic therapy is mostly empirical. MATERIALS AND METHODS: This study was conducted at Nizam's Institute of Medical Sciences, Hyderabad. Turbid urine samples which showed pus cells and Gram-negative (GN) bacilli of single morphotype were included...
July 2018: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/29998060/pneumococcal-urinary-antigen-test-a-tool-for-pneumococcal-aortitis-diagnosis
#11
Stanislas Abrard, Benoit Cousin, Thomas Reydel, Myriam Ammi, Laurent Beydon
Introduction: Aortitis is rare. The etiological diagnosis is difficult but essential for treatment. Even with appropriate treatment mortality remains high. We present a case of pneumococcal aortitis followed by a brief review of the literature. Presentation of Case: In this case, the aortic disease was characterized by multiple inflammatory aneurysms. Blood cultures were negative but urine was tested for the presence of pneumococcal urinary antigen postoperatively was positive...
2018: IDCases
https://www.readbyqxmd.com/read/29981885/a-decision-support-system-for-antibiotic-prescription-based-on-local-cumulative-antibiograms
#12
Antonio Morales, Manuel Campos, Jose M Juarez, Bernardo Canovas-Segura, Francisco Palacios, Roque Marin
BACKGROUND: Local cumulative antibiograms are useful tools with which to select appropriate empiric or directed therapies when treating infectious diseases at a hospital. However, data represented in traditional antibiograms are static, incomplete and not well adapted to decision-making. METHODS: We propose a decision support method for empiric antibiotic therapy based on the Number Needed to Fail (NNF) measure. NNF indicates the number of patients that would need to be treated with a specific antibiotic for one to be inadequately treated...
August 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29937071/prospective-evaluation-of-predictive-parameters-for-urinary-tract-infection-in-patients-with-acute-renal-colic
#13
Bernd Rosenhammer, Philipp J Spachmann, Maximilian Burger, Hans-Martin Fritsche, Marco J Schnabel
BACKGROUND: Acute renal colic (ARC) is an emergency that can mostly be treated conservatively, but can be life threatening in combination with urinary tract infection (UTI). Assessment for infection includes white blood cell (WBC) count and C-reactive protein (CRP), but these parameters are often unspecifically elevated and might lead to antibiotic over-therapy. In times of increasing antibiotic resistance, however, unnecessary antibiotic therapy should be avoided. OBJECTIVES: The goal of the study was to investigate the prevalence of UTI proven by urine culture (UC) in patients with ARC and to identify predictive factors in the emergency setting...
September 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29804552/modified-reporting-of-positive-urine-cultures-to-reduce-inappropriate-treatment-of-asymptomatic-bacteriuria-among-nonpregnant-noncatheterized-inpatients-a-randomized-controlled-trial
#14
Peter Daley, David Garcia, Raheel Inayatullah, Carla Penney, Sarah Boyd
DESIGNWe conducted a randomized, parallel, unblinded, superiority trial of a laboratory reporting intervention designed to reduce antibiotic treatment of asymptomatic bacteriuria (ASB).METHODSResults of positive urine cultures from 110 consecutive inpatients at 2 urban acute-care hospitals were randomized to standard report (control) or modified report (intervention). The standard report included bacterial count, bacterial identification, and antibiotic susceptibility information including drug dosage and cost...
July 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29790623/the-analysis-of-microbial-spectrum-and-antibiotic-resistance-of-uropathogens-isolated-from-patients-with-urinary-stones
#15
Dong Chen, Yuyan Zhang, Jian Huang, Xiongfa Liang, Tao Zeng, Chuangxin Lan, Xiaolu Duan, Zhijian Zhao, Guohua Zeng, Hans-Göran Tiselius, Xiaogang Lu, Wenqi Wu
PURPOSE: The characteristics and resistance patterns of urine bacteriology in patients with urinary tract stones have not been extensively studied. This study aims to investigate the microbial spectrum and antibiotic resistance of uropathogens isolated from urinary tract infections in patients with urinary stones and provide a basis for appropriate antimicrobial treatments. METHODS: The results of positive bladder midstream urine cultures and their antimicrobial susceptibility were retrospectively analysed from hospitalised patients with diagnosis of urinary calculi and urinary tract infections between January 2010 and December 2015...
June 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29777488/no-need-for-a-urine-culture-in-elderly-hospitalized-patients-with-a-negative-dipstick-test-result
#16
Zvi Shimoni, Vered Hermush, Joseph Glick, Paul Froom
To determine the clinical utility/disutility of canceling urine cultures in elderly patients with a negative dipstick. The cohort included consecutive patients aged ≥ 65 years hospitalized in internal medicine departments with an admission urinalysis and urine culture (January 1, 2014 to December 31, 2016). We calculated the sensitivity of the dipstick (either a trace leukocyte esterase or a positive nitrite test result) to detect patients with bacteriuria, and the decrease in urine cultures resulting from cancelation in patients with a negative dipstick...
August 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29769025/use-of-diagnostic-tests-and-the-appropriateness-of-the-treatment-decision-in-patients-with-suspected-urinary-tract-infection-in-primary-care-in-denmark-observational-study
#17
Gloria Córdoba, Anne Holm, Tina Møller Sørensen, Volkert Siersma, Håkon Sandholdt, Marjukka Makela, Niels Frimodt-Møller, Lars Bjerrum
BACKGROUND: Inappropriate prescription of antibiotics is the leading driver of antimicrobial resistance (AMR). The majority of antibiotics are prescribed in primary care. Understanding how general practitioners (GPs) use diagnostic tests and the effect on treatment decision under daily practice conditions is important to reduce inappropriate prescription of antibiotics. The aim of the study was to investigate the use of diagnostic tests in primary care patients with suspected urinary tract infection (UTI) and to assess the appropriateness of the treatment decision (TD) under daily practice conditions in Denmark...
May 16, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29713357/torch-toxoplasmosis-rubella-cytomegalovirus-and-herpes-simplex-virus-screening-of-small-for-gestational-age-and-intrauterine-growth-restricted-neonates-efficacy-study-in-a-single-institute-in-korea
#18
Mi Hae Chung, Chan Ok Shin, Juyoung Lee
Purpose: Routine screening for toxoplasmosis, rubella, cytomegalovirus (CMV), and herpes simplex virus (TORCH) in intrauterine growth restriction (IUGR) and small for gestational age (SGA) neonates has become a common practice. However, the incidence of TORCH varies across countries, and the cost of TORCH testing may be disadvantageous compared to disease-specific screening. To evaluate the efficacy of TORCH screening, the medical charts of IUGR or SGA neonates born in a single institution in Bucheon, Korea from 2011 to 2015 were reviewed...
April 2018: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29708840/prevalence-and-antimicrobial-susceptibility-of-ureaplasma-spp-and-mycoplasma-hominis-in-asymptomatic-individuals-in-korea
#19
Jin Bong Choi, Seung-Ju Lee, Mi-Kyung Lee, Sung-Jong Lee, Dong Choon Park, Hee Youn Kim, Dong Sup Lee, Hyun-Sop Choe
This study investigated the prevalence and antibiotic resistance of Ureaplasma spp. and Mycoplasma hominis isolated from asymptomatic individuals in Korea. Endocervical swabs from women and urine from men, from a total of 5,781 asymptomatic individuals, were analyzed using a Mycoplasma IST2 Kit. Of the 4,825 specimens tested from females, 486 (10.1%) were positive culture. In these positive specimens, 437 (9.1%) were positive only for Ureaplasma spp., 17 (0.4%) were positive only for M. hominis, and 32 (0.7%) were positive for both Ureaplasma spp...
April 30, 2018: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29695265/antimicrobial-resistance-among-clinically-relevant-bacterial-isolates-in-accra-a-retrospective-study
#20
Jibril Mohammed, Yaovi Mahuton Gildas Hounmanou, Line Elnif Thomsen
OBJECTIVE: The aim of this study was to determine the antimicrobial resistance pattern of bacterial isolates from different specimens at various hospitals and private diagnostic service laboratories in Ghana. RESULTS: A retrospective data of culture and sensitivity test results from 2016 were extracted from the microbiology record book of six laboratories in Accra, Ghana. The data included type of clinical specimen, sex of patient, name of bacterial isolate and antibiotic resistance profile...
April 25, 2018: BMC Research Notes
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