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appropriate urine culture

Giovanni Lorenzin, Giorgio Piccinelli, Lucrezia Carlassara, Francesco Scolari, Francesca Caccuri, Arnaldo Caruso, Maria Antonia De Francesco
Background: Myroides spp. are common environmental organisms and they can be isolated predominantly in water, soil, food and in sewage treatment plants. In the last two decades, an increasing number of infections such as urinary tract infections and skin and soft tissue infections, caused by these microorganisms has been reported. Selection of appropriate antibiotic therapy to treat the infections caused by Myroides spp . is difficult due to the production of a biofilm and the organism's intrinsic resistance to many antibiotic classes...
2018: Antimicrobial Resistance and Infection Control
Neelima Angaali, Laxmi Vemu, Chavali Padmasri, Neeraja Mamidi, Vijay Dharma Teja
INTRODUCTION: Urinary tract infections (UTIs) are the most common infectious diseases occurring in either the community or healthcare setting. Turnaround time for urine culture is about 24 h, and antimicrobial susceptibility testing (AST) requires another 24 h. Consequently, initial antibiotic therapy is mostly empirical. MATERIALS AND METHODS: This study was conducted at Nizam's Institute of Medical Sciences, Hyderabad. Turbid urine samples which showed pus cells and Gram-negative (GN) bacilli of single morphotype were included...
July 2018: Journal of Laboratory Physicians
Stanislas Abrard, Benoit Cousin, Thomas Reydel, Myriam Ammi, Laurent Beydon
Introduction: Aortitis is rare. The etiological diagnosis is difficult but essential for treatment. Even with appropriate treatment mortality remains high. We present a case of pneumococcal aortitis followed by a brief review of the literature. Presentation of Case: In this case, the aortic disease was characterized by multiple inflammatory aneurysms. Blood cultures were negative but urine was tested for the presence of pneumococcal urinary antigen postoperatively was positive...
2018: IDCases
Antonio Morales, Manuel Campos, Jose M Juarez, Bernardo Canovas-Segura, Francisco Palacios, Roque Marin
BACKGROUND: Local cumulative antibiograms are useful tools with which to select appropriate empiric or directed therapies when treating infectious diseases at a hospital. However, data represented in traditional antibiograms are static, incomplete and not well adapted to decision-making. METHODS: We propose a decision support method for empiric antibiotic therapy based on the Number Needed to Fail (NNF) measure. NNF indicates the number of patients that would need to be treated with a specific antibiotic for one to be inadequately treated...
August 2018: Journal of Biomedical Informatics
Bernd Rosenhammer, Philipp J Spachmann, Maximilian Burger, Hans-Martin Fritsche, Marco J Schnabel
BACKGROUND: Acute renal colic (ARC) is an emergency that can mostly be treated conservatively, but can be life threatening in combination with urinary tract infection (UTI). Assessment for infection includes white blood cell (WBC) count and C-reactive protein (CRP), but these parameters are often unspecifically elevated and might lead to antibiotic over-therapy. In times of increasing antibiotic resistance, however, unnecessary antibiotic therapy should be avoided. OBJECTIVES: The goal of the study was to investigate the prevalence of UTI proven by urine culture (UC) in patients with ARC and to identify predictive factors in the emergency setting...
June 21, 2018: Journal of Emergency Medicine
Peter Daley, David Garcia, Raheel Inayatullah, Carla Penney, Sarah Boyd
DESIGNWe conducted a randomized, parallel, unblinded, superiority trial of a laboratory reporting intervention designed to reduce antibiotic treatment of asymptomatic bacteriuria (ASB).METHODSResults of positive urine cultures from 110 consecutive inpatients at 2 urban acute-care hospitals were randomized to standard report (control) or modified report (intervention). The standard report included bacterial count, bacterial identification, and antibiotic susceptibility information including drug dosage and cost...
July 2018: Infection Control and Hospital Epidemiology
Dong Chen, Yuyan Zhang, Jian Huang, Xiongfa Liang, Tao Zeng, Chuangxin Lan, Xiaolu Duan, Zhijian Zhao, Guohua Zeng, Hans-Göran Tiselius, Xiaogang Lu, Wenqi Wu
PURPOSE: The characteristics and resistance patterns of urine bacteriology in patients with urinary tract stones have not been extensively studied. This study aims to investigate the microbial spectrum and antibiotic resistance of uropathogens isolated from urinary tract infections in patients with urinary stones and provide a basis for appropriate antimicrobial treatments. METHODS: The results of positive bladder midstream urine cultures and their antimicrobial susceptibility were retrospectively analysed from hospitalised patients with diagnosis of urinary calculi and urinary tract infections between January 2010 and December 2015...
June 2018: International Journal of Clinical Practice
Zvi Shimoni, Vered Hermush, Joseph Glick, Paul Froom
To determine the clinical utility/disutility of canceling urine cultures in elderly patients with a negative dipstick. The cohort included consecutive patients aged ≥ 65 years hospitalized in internal medicine departments with an admission urinalysis and urine culture (January 1, 2014 to December 31, 2016). We calculated the sensitivity of the dipstick (either a trace leukocyte esterase or a positive nitrite test result) to detect patients with bacteriuria, and the decrease in urine cultures resulting from cancelation in patients with a negative dipstick...
August 2018: European Journal of Clinical Microbiology & Infectious Diseases
Gloria Córdoba, Anne Holm, Tina Møller Sørensen, Volkert Siersma, Håkon Sandholdt, Marjukka Makela, Niels Frimodt-Møller, Lars Bjerrum
BACKGROUND: Inappropriate prescription of antibiotics is the leading driver of antimicrobial resistance (AMR). The majority of antibiotics are prescribed in primary care. Understanding how general practitioners (GPs) use diagnostic tests and the effect on treatment decision under daily practice conditions is important to reduce inappropriate prescription of antibiotics. The aim of the study was to investigate the use of diagnostic tests in primary care patients with suspected urinary tract infection (UTI) and to assess the appropriateness of the treatment decision (TD) under daily practice conditions in Denmark...
May 16, 2018: BMC Family Practice
Mi Hae Chung, Chan Ok Shin, Juyoung Lee
Purpose: Routine screening for toxoplasmosis, rubella, cytomegalovirus (CMV), and herpes simplex virus (TORCH) in intrauterine growth restriction (IUGR) and small for gestational age (SGA) neonates has become a common practice. However, the incidence of TORCH varies across countries, and the cost of TORCH testing may be disadvantageous compared to disease-specific screening. To evaluate the efficacy of TORCH screening, the medical charts of IUGR or SGA neonates born in a single institution in Bucheon, Korea from 2011 to 2015 were reviewed...
April 2018: Korean Journal of Pediatrics
Jin Bong Choi, Seung-Ju Lee, Mi-Kyung Lee, Sung-Jong Lee, Dong Choon Park, Hee Youn Kim, Dong Sup Lee, Hyun-Sop Choe
This study investigated the prevalence and antibiotic resistance of Ureaplasma spp. and Mycoplasma hominis isolated from asymptomatic individuals in Korea. Endocervical swabs from women and urine from men, from a total of 5,781 asymptomatic individuals, were analyzed using a Mycoplasma IST2 Kit. Of the 4,825 specimens tested from females, 486 (10.1%) were positive culture. In these positive specimens, 437 (9.1%) were positive only for Ureaplasma spp., 17 (0.4%) were positive only for M. hominis, and 32 (0.7%) were positive for both Ureaplasma spp...
April 30, 2018: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
Jibril Mohammed, Yaovi Mahuton Gildas Hounmanou, Line Elnif Thomsen
OBJECTIVE: The aim of this study was to determine the antimicrobial resistance pattern of bacterial isolates from different specimens at various hospitals and private diagnostic service laboratories in Ghana. RESULTS: A retrospective data of culture and sensitivity test results from 2016 were extracted from the microbiology record book of six laboratories in Accra, Ghana. The data included type of clinical specimen, sex of patient, name of bacterial isolate and antibiotic resistance profile...
April 25, 2018: BMC Research Notes
Shreya Basu, Mandira Mukherjee
BACKGROUND: Co-resistance against fluroquinolone(FQ) and β-lactams cause treatment complications in infections caused by uropathogenic E.coli(UPEC).This study aims to detect coexistence and co-transmission of plasmid-mediated quinolone resistant(PMQR) and extended spectrum β-lactamases (ESBLs) in UPECs from Kolkata,India. METHODS: E. coli was detected biochemically from urine culture positive samples. Antibiotic resistance and ESBL production was confirmed by disk diffusion assay...
March 31, 2018: Journal of Global Antimicrobial Resistance
Suzan Gunduz, Hatice Uludağ Altun
Background: Knowledge of local antimicrobial resistance patterns is essential for evidence- based empirical antibiotic prescribing. We aimed to investigate the distribution and changes in causative agents of urinary tract infections in children and the resistance rates, and to recommend the most appropriate antibiotics. Methods: In this retrospective study, we evaluated causative agents and antimicrobial resistance in urine isolates from the positive community from September 2014 to April 2016 in a single hospital in Ankara, Turkey...
2018: Global health research and policy
Z Meidani, G A Mousavi, D Kheirkhah, N Benar, M R Maleki, M Sharifi, A Farrokhian
Studies indicate there are a variety of contributing factors affecting physician test ordering behaviour. Identifying these behaviours allows development of behaviour-based interventions. Methods Through a pilot study, the list of contributing factors in laboratory tests ordering, and the most ordered tests, were identified, and given to 50 medical students, interns, residents and paediatricians in questionnaire form. The results showed routine tests and peer or supervisor pressure as the most influential factors affecting physician ordering behaviour...
December 2017: Journal of the Royal College of Physicians of Edinburgh
Jurate Noreikaite, Patrick Jones, John Fitzpatrick, Ramachandran Amitharaj, Amelia Pietropaolo, Nikhil Vasdev, David Chadwick, Bhaskar K Somani, Bhavan Prasad Rai
BACKGROUND: Infection-related complications secondary to quinolone resistance have been on the rise following transrectal ultrasound-guided biopsy of the prostate (TRUSBP). The aim of this review was to compare the efficacy of fosfomycin with quinolone-based antibiotic prophylaxis for TRUSBP. METHODS: A systematic review in line with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) and Cochrane guidelines was conducted. All studies comparing fosfomycin vs...
June 2018: Prostate Cancer and Prostatic Diseases
Christopher C Butler, Nick A Francis, Emma Thomas-Jones, Mirella Longo, Mandy Wootton, Carl Llor, Paul Little, Michael Moore, Janine Bates, Timothy Pickles, Nigel Kirby, David Gillespie, Kate Rumsby, Curt Brugman, Micaela Gal, Kerenza Hood, Theo Verheij
BACKGROUND: The effectiveness of using point-of-care (POC) urine culture in primary care on appropriate antibiotic use is unknown. AIM: To assess whether use of the Flexicult™ SSI-Urinary Kit, which quantifies bacterial growth and determines antibiotic susceptibility at the point of care, achieves antibiotic use that is more often concordant with laboratory culture results, when compared with standard care. DESIGN AND SETTING: Individually randomised trial of females with uncomplicated urinary tract infection (UTI) in primary care research networks (PCRNs) in England, the Netherlands, Spain, and Wales...
April 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
T M Sørensen, C R Bjørnvad, G Cordoba, P Damborg, L Guardabassi, V Siersma, L Bjerrum, L R Jessen
BACKGROUND: Clinical signs of urinary tract disease in dogs often lead to prescription of antibiotics. Appropriate diagnostic work-up could optimize treatment and reduce the risk of inappropriate use of antibiotics. HYPOTHESIS/OBJECTIVES: To describe and evaluate the impact of diagnostic work-up on decision to treat (DTT) and choice of antibiotic treatment (COT) for dogs presenting with clinical signs of urinary tract disease. ANIMALS: One hundred and fifty-one dogs presenting to 52 Danish veterinary practices...
March 2018: Journal of Veterinary Internal Medicine
Christine M Chu, Jerry L Lowder
Urinary tract infections are the most common outpatient infections, but predicting the probability of urinary tract infections through symptoms and test results can be complex. The most diagnostic symptoms of urinary tract infections include change in frequency, dysuria, urgency, and presence or absence of vaginal discharge, but urinary tract infections may present differently in older women. Dipstick urinalysis is popular for its availability and usefulness, but results must be interpreted in context of the patient's pretest probability based on symptoms and characteristics...
July 2018: American Journal of Obstetrics and Gynecology
Cagri Senocak, Cihat Ozcan, Tolga Sahin, Gulden Yilmaz, Ekrem Ozyuvali, Selcuk Sarikaya, Berkan Resorlu, Ural Oguz, Omer Faruk Bozkurt, Ali Unsal, Oztug Adsan
PURPOSE: To determine the perioperative risk factors for postoperative infections among patients undergoing flexible uretero-renoscopy with laser lithotripsy (FURSLL). In addition, the resistance patterns of pathogens isolated from positive preoperative urine cultures were investigated. MATERIALS AND METHODS: We retrospectively reviewed data from 492 consecutive patients who had undergone FURSLL for stone disease in our department. Postoperative infection was defined as fever (? 38°C) with pyuria (? 10 white blood cells per high power field), or systemic inflammatory response syndrome, or sepsis...
July 10, 2018: Urology Journal
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